NP-MRD: Showing NP-Card for (5R,7R,8R,9R,10S)-15,16-Epoxy-7,9-dihydroxylabdan-13(16),14-dien-3,6-dione (NP0353188)

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Record Information

Version

2.0

Created at

2026-02-18 16:46:15 UTC

Updated at

2026-02-18 20:01:44 UTC

NP-MRD ID

NP0353188

Natural Product DOI

https://doi.org/10.57994/7606

Secondary Accession Numbers

None

Natural Product Identification

Common Name

(5R,7R,8R,9R,10S)-15,16-Epoxy-7,9-dihydroxylabdan-13(16),14-dien-3,6-dione

Description

(5R,7R,8R,9R,10S)-15,16-Epoxy-7,9-dihydroxylabdan-13(16),14-dien-3,6-dione was first documented in 2019 (PMID: 31503485).

Structure

MOL SDF PDB SMILES InChI


  Mrv2104 03192313582D          

 26 28  0  0  1  0            999 V2000
    1.4289   -0.8250    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -1.2375    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.0000   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000   -2.4750    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -1.2375    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -1.4289   -1.6500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -0.4125    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.4289    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -0.0000    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.5303    0.6320    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5303    0.6320    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2481    1.4072    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5643    1.5505    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9260    2.2920    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7430    2.1772    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.8862    1.3647    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1578    0.9774    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.7145    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -1.6500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8163   -2.3784    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0416   -2.3784    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  2  1  1  1  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  5  3  1  0  0  0  0
  5  6  1  6  0  0  0
  7  5  1  0  0  0  0
  7  8  1  1  0  0  0
  7  9  1  0  0  0  0
  9 10  1  1  0  0  0
  9 11  1  6  0  0  0
 11 12  1  0  0  0  0
 12 13  1  0  0  0  0
 13 14  2  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  2  0  0  0  0
 13 17  1  0  0  0  0
  9 18  1  0  0  0  0
 18  2  1  0  0  0  0
 18 19  1  6  0  0  0
 18 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  2  0  0  0  0
 22 24  1  0  0  0  0
  2 24  1  0  0  0  0
 24 25  1  0  0  0  0
 24 26  1  0  0  0  0
M  END


  Mrv2104 03192313582D          

 26 28  0  0  1  0            999 V2000
    1.4289   -0.8250    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -1.2375    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.0000   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000   -2.4750    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -1.2375    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -1.4289   -1.6500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -0.4125    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.4289    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -0.0000    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.5303    0.6320    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5303    0.6320    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2481    1.4072    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5643    1.5505    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9260    2.2920    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7430    2.1772    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.8862    1.3647    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1578    0.9774    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.7145    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -1.6500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8163   -2.3784    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0416   -2.3784    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  2  1  1  1  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  5  3  1  0  0  0  0
  5  6  1  6  0  0  0
  7  5  1  0  0  0  0
  7  8  1  1  0  0  0
  7  9  1  0  0  0  0
  9 10  1  1  0  0  0
  9 11  1  6  0  0  0
 11 12  1  0  0  0  0
 12 13  1  0  0  0  0
 13 14  2  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  2  0  0  0  0
 13 17  1  0  0  0  0
  9 18  1  0  0  0  0
 18  2  1  0  0  0  0
 18 19  1  6  0  0  0
 18 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  2  0  0  0  0
 22 24  1  0  0  0  0
  2 24  1  0  0  0  0
 24 25  1  0  0  0  0
 24 26  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0353188

> <DATABASE_NAME>
NP-MRD

> <SMILES>
[H][C@@]12C(=O)[C@H](O)[C@@H](C)[C@](O)(CCC3=COC=C3)[C@@]1(C)CCC(=O)C2(C)C

> <INCHI_IDENTIFIER>
InChI=1S/C20H28O5/c1-12-15(22)16(23)17-18(2,3)14(21)6-8-19(17,4)20(12,24)9-5-13-7-10-25-11-13/h7,10-12,15,17,22,24H,5-6,8-9H2,1-4H3/t12-,15-,17+,19+,20-/m1/s1

> <INCHI_KEY>
PJGZGIKJCNSSNE-GRAJNTMJSA-N

> <FORMULA>
C20H28O5

> <MOLECULAR_WEIGHT>
348.439

> <EXACT_MASS>
348.193674002

$$$$

HEADER    PROTEIN                                 19-MAR-23   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   19-MAR-23         0                                  
HETATM    1  H   UNK     0       2.667  -1.540   0.000  0.00  0.00           H+0
HETATM    2  C   UNK     0       1.334  -2.310   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      -0.000  -3.080   0.000  0.00  0.00           C+0
HETATM    4  O   UNK     0      -0.000  -4.620   0.000  0.00  0.00           O+0
HETATM    5  C   UNK     0      -1.334  -2.310   0.000  0.00  0.00           C+0
HETATM    6  O   UNK     0      -2.667  -3.080   0.000  0.00  0.00           O+0
HETATM    7  C   UNK     0      -1.334  -0.770   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0      -2.667   0.000   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       0.000  -0.000   0.000  0.00  0.00           C+0
HETATM   10  O   UNK     0       0.990   1.180   0.000  0.00  0.00           O+0
HETATM   11  C   UNK     0      -0.990   1.180   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0      -0.463   2.627   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       1.053   2.894   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       1.729   4.278   0.000  0.00  0.00           C+0
HETATM   15  O   UNK     0       3.254   4.064   0.000  0.00  0.00           O+0
HETATM   16  C   UNK     0       3.521   2.547   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       2.161   1.824   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       1.334  -0.770   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       1.334   0.770   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0       2.667  -0.000   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0       4.001  -0.770   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0       4.001  -2.310   0.000  0.00  0.00           C+0
HETATM   23  O   UNK     0       5.335  -3.080   0.000  0.00  0.00           O+0
HETATM   24  C   UNK     0       2.667  -3.080   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0       3.390  -4.440   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0       1.944  -4.440   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3   18   24                                             
CONECT    3    2    4    5                                                  
CONECT    4    3                                                            
CONECT    5    3    6    7                                                  
CONECT    6    5                                                            
CONECT    7    5    8    9                                                  
CONECT    8    7                                                            
CONECT    9    7   10   11   18                                             
CONECT   10    9                                                            
CONECT   11    9   12                                                       
CONECT   12   11   13                                                       
CONECT   13   12   14   17                                                  
CONECT   14   13   15                                                       
CONECT   15   14   16                                                       
CONECT   16   15   17                                                       
CONECT   17   16   13                                                       
CONECT   18    9    2   19   20                                             
CONECT   19   18                                                            
CONECT   20   18   21                                                       
CONECT   21   20   22                                                       
CONECT   22   21   23   24                                                  
CONECT   23   22                                                            
CONECT   24   22    2   25   26                                             
CONECT   25   24                                                            
CONECT   26   24                                                            
MASTER        0    0    0    0    0    0    0    0   26    0   56    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₂₀H₂₈O₅

Average Mass

348.4390 Da

Monoisotopic Mass

348.19367 Da

IUPAC Name

Not Available

Traditional Name

Not Available

CAS Registry Number

Not Available

SMILES

[H][C@@]12C(=O)[C@H](O)[C@@H](C)[C@](O)(CCC3=COC=C3)[C@@]1(C)CCC(=O)C2(C)C

InChI Identifier

InChI=1S/C20H28O5/c1-12-15(22)16(23)17-18(2,3)14(21)6-8-19(17,4)20(12,24)9-5-13-7-10-25-11-13/h7,10-12,15,17,22,24H,5-6,8-9H2,1-4H3/t12-,15-,17+,19+,20-/m1/s1

InChI Key

PJGZGIKJCNSSNE-GRAJNTMJSA-N

Experimental Spectra

Spectrum Type	Description	Depositor Email	Depositor Organization	Depositor	Deposition Date	View

Predicted Spectra

Not Available

Chemical Shift Submissions

Spectrum Type	Description	Depositor Email	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹H NMR Spectrum (1D, 600.0, Chloroform-d, simulated)	[email protected]	Not Available	Not Available	2026-02-18	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 150.0, Chloroform-d, simulated)	[email protected]	Not Available	Not Available	2026-02-18	View Spectrum

Species

Species of Origin

Species Name	Source	Reference
Leonurus japonicus		Not Available

Chemical Taxonomy

Classification

Not classified

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source

External Links

Not Available

References

General References

Showing NP-Card for (5R,7R,8R,9R,10S)-15,16-Epoxy-7,9-dihydroxylabdan-13(16),14-dien-3,6-dione (NP0353188)

MOL for NP0353188 ((5R,7R,8R,9R,10S)-15,16-Epoxy-7,9-dihydroxylabdan-13(16),14-dien-3,6-dione)

3D MOL for NP0353188 ((5R,7R,8R,9R,10S)-15,16-Epoxy-7,9-dihydroxylabdan-13(16),14-dien-3,6-dione)

3D SDF for NP0353188 ((5R,7R,8R,9R,10S)-15,16-Epoxy-7,9-dihydroxylabdan-13(16),14-dien-3,6-dione)

3D-SDF for NP0353188 ((5R,7R,8R,9R,10S)-15,16-Epoxy-7,9-dihydroxylabdan-13(16),14-dien-3,6-dione)

PDB for NP0353188 ((5R,7R,8R,9R,10S)-15,16-Epoxy-7,9-dihydroxylabdan-13(16),14-dien-3,6-dione)

3D PDB for NP0353188 ((5R,7R,8R,9R,10S)-15,16-Epoxy-7,9-dihydroxylabdan-13(16),14-dien-3,6-dione)

SMILES for NP0353188 ((5R,7R,8R,9R,10S)-15,16-Epoxy-7,9-dihydroxylabdan-13(16),14-dien-3,6-dione)

INCHI for NP0353188 ((5R,7R,8R,9R,10S)-15,16-Epoxy-7,9-dihydroxylabdan-13(16),14-dien-3,6-dione)

Structure for NP0353188 ((5R,7R,8R,9R,10S)-15,16-Epoxy-7,9-dihydroxylabdan-13(16),14-dien-3,6-dione)

3D Structure for NP0353188 ((5R,7R,8R,9R,10S)-15,16-Epoxy-7,9-dihydroxylabdan-13(16),14-dien-3,6-dione)