| Record Information |
|---|
| Version | 2.0 |
|---|
| Created at | 2024-09-11 10:34:59 UTC |
|---|
| Updated at | 2024-09-11 10:34:59 UTC |
|---|
| NP-MRD ID | NP0337379 |
|---|
| Secondary Accession Numbers | None |
|---|
| Natural Product Identification |
|---|
| Common Name | Thaumatin |
|---|
| Description | Traumatin, also known as 12-oxo-10t-12:1 Or Delta(10)-oda, belongs to the class of organic compounds known as medium-chain fatty acids. These are fatty acids with an aliphatic tail that contains between 4 and 12 carbon atoms. Thus, traumatin is considered to be a fatty acid lipid molecule. Traumatin is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral. Traumatin is an odorless tasting compound. Outside of the human body, Traumatin has been detected, but not quantified in, fruits. This could make traumatin a potential biomarker for the consumption of these foods. Thaumatin has been approved as a sweetener in the European Union (E957), Israel, and Japan. The thaumatin protein is considered a prototype for a pathogen-response protein domain. The proteins are involved in systematically acquired resistance and stress response in plants, although their precise role is unknown. This thaumatin domain has been found in species as diverse as rice and Caenorhabditis elegans. ; Thaumatin production is induced in katemfe in response to an attack upon the plant by viroid pathogens. ; Thaumatin is a low-calorie (virtually calorie-free) protein sweetener and flavour modifier. Thaumatins are pathogenesis related (PR) proteins, which are induced by various agents ranging from ethylene to pathogens, are structurally diverse and apparently ubiquitous in plants: They include thaumatin, osmotin, tobacco major and minor PR proteins, alpha-amylase/trypsin inhibitor, and P21 and PWIR2 soybean and wheat leaf proteins. Thaumatin is an intensely sweet tasting protein (on a molar basis about 100,000 times as sweet as sucrose) found in the West African shrub Thaumatococcus daniellii: It is induced by attack by viroids, which are single-stranded unencapsulated RNA molecules that do not code for protein. In the United States, it is a Generally Recognized as Safe flavoring agent (FEMA GRAS 3732). Thaumatin was first documented in 1979 (PMID: 16660762). Sweetener (5,000 times sweeter than sucrose), flavour enhancer for coffee, peppermint flavours etc. |
|---|
| Structure | InChI=1S/C12H20O3/c13-11-9-7-5-3-1-2-4-6-8-10-12(14)15/h7,9,11H,1-6,8,10H2,(H,14,15)/b9-7+ |
|---|
| Synonyms | | Value | Source |
|---|
| (10E)-12-Oxododecenoic acid | ChEBI | | (e)-12-Oxododec-10-enoic acid | ChEBI | | 12-oxo-(e)-10-Dodecenoic acid | ChEBI | | 12-oxo-10E-Dodecenoic acid | ChEBI | | 12-oxo-10t-12:1 | ChEBI | | 12-oxo-10t-C12:1 | ChEBI | | 12-oxo-Dodec-10t-enoic acid | ChEBI | | 12-oxo-Dodec-10t-ensaeure | ChEBI | | 12-oxo-trans-Dodec-10-enoic acid | ChEBI | | Delta(10)-ODA | ChEBI | | (10E)-12-Oxododecenoate | Generator | | (e)-12-Oxododec-10-enoate | Generator | | 12-oxo-(e)-10-Dodecenoate | Generator | | 12-oxo-10E-Dodecenoate | Generator | | 12-oxo-Dodec-10t-enoate | Generator | | 12-oxo-trans-Dodec-10-enoate | Generator | | Δ(10)-oda | Generator | | (10E)-12-Oxododec-10-enoic acid | HMDB | | (e)-12-oxo-10-Dodecanoic acid | HMDB | | 12-oxo-(e)-10-Dodecanoic acid | HMDB | | 12-oxo-10(e)-Dodecenoic acid | HMDB | | Delta10-Oda | HMDB | | Traumatic half aldehyde | HMDB | | Traumatin | ChEBI | | (10E)-12-Oxo-10-dodecenoic acid | HMDB | | 12-Oxo-trans-10-dodecenoic acid | HMDB |
| Show more...
|---|
| Chemical Formula | C12H20O3 |
|---|
| Average Mass | 212.2854 Da |
|---|
| Monoisotopic Mass | 212.14124 Da |
|---|
| IUPAC Name | (10E)-12-oxododec-10-enoic acid |
|---|
| Traditional Name | traumatin |
|---|
| CAS Registry Number | Not Available |
|---|
| SMILES | OC(=O)CCCCCCCC\C=C\C=O |
|---|
| InChI Identifier | InChI=1S/C12H20O3/c13-11-9-7-5-3-1-2-4-6-8-10-12(14)15/h7,9,11H,1-6,8,10H2,(H,14,15)/b9-7+ |
|---|
| InChI Key | INMKWUNQKOWGEZ-VQHVLOKHSA-N |
|---|
| Experimental Spectra |
|---|
|
| Not Available |
|---|
| Predicted Spectra |
|---|
|
| Not Available |
|---|
| Chemical Shift Submissions |
|---|
|
| Not Available |
|---|
| Species |
|---|
| Species of Origin | Not Available |
|---|
| Chemical Taxonomy |
|---|
| Description | Belongs to the class of organic compounds known as medium-chain fatty acids. These are fatty acids with an aliphatic tail that contains between 4 and 12 carbon atoms. |
|---|
| Kingdom | Organic compounds |
|---|
| Super Class | Lipids and lipid-like molecules |
|---|
| Class | Fatty Acyls |
|---|
| Sub Class | Fatty acids and conjugates |
|---|
| Direct Parent | Medium-chain fatty acids |
|---|
| Alternative Parents | |
|---|
| Substituents | - Medium-chain fatty acid
- Unsaturated fatty acid
- Straight chain fatty acid
- Enal
- Alpha,beta-unsaturated aldehyde
- Monocarboxylic acid or derivatives
- Carboxylic acid
- Carboxylic acid derivative
- Organic oxygen compound
- Organic oxide
- Hydrocarbon derivative
- Organooxygen compound
- Carbonyl group
- Aldehyde
- Aliphatic acyclic compound
|
|---|
| Molecular Framework | Aliphatic acyclic compounds |
|---|
| External Descriptors | |
|---|
| Physical Properties |
|---|
| State | Not Available |
|---|
| Experimental Properties | | Property | Value | Reference |
|---|
| Melting Point | Not Available | Not Available | | Boiling Point | Not Available | Not Available | | Water Solubility | Not Available | Not Available | | LogP | Not Available | Not Available |
|
|---|
| Predicted Properties | |
|---|
