Record Information |
---|
Version | 2.0 |
---|
Created at | 2024-09-10 22:47:22 UTC |
---|
Updated at | 2024-09-10 22:47:22 UTC |
---|
NP-MRD ID | NP0334853 |
---|
Secondary Accession Numbers | None |
---|
Natural Product Identification |
---|
Common Name | L-Canavanine |
---|
Description | L-Canavanine belongs to the class of organic compounds known as alpha amino acids. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon). L-Canavanine was first documented in 2006 (PMID: 30000890). Based on a literature review a significant number of articles have been published on L-Canavanine (PMID: 33032148) (PMID: 32839635) (PMID: 38941218) (PMID: 38577885) (PMID: 37852416) (PMID: 36173493). |
---|
Structure | InChI=1/C5H12N4O3/c6-3(4(10)11)1-2-12-9-5(7)8/h3H,1-2,6H2,(H,10,11)(H4,7,8,9) |
---|
Synonyms | Not Available |
---|
Chemical Formula | C5H12N4O3 |
---|
Average Mass | 176.1760 Da |
---|
Monoisotopic Mass | 176.09094 Da |
---|
IUPAC Name | 2-amino-4-{[(diaminomethylidene)amino]oxy}butanoic acid |
---|
Traditional Name | DL-canavanine |
---|
CAS Registry Number | Not Available |
---|
SMILES | NC(CCON=C(N)N)C(O)=O |
---|
InChI Identifier | InChI=1/C5H12N4O3/c6-3(4(10)11)1-2-12-9-5(7)8/h3H,1-2,6H2,(H,10,11)(H4,7,8,9) |
---|
InChI Key | FSBIGDSBMBYOPN-UHFFFAOYNA-N |
---|
Experimental Spectra |
---|
|
| Not Available | Predicted Spectra |
---|
|
| Not Available | Chemical Shift Submissions |
---|
|
| Not Available | Species |
---|
Species of Origin | Not Available |
---|
Chemical Taxonomy |
---|
Description | This compound belongs to the class of organic compounds known as alpha amino acids. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon). |
---|
Kingdom | Organic compounds |
---|
Super Class | Organic acids and derivatives |
---|
Class | Carboxylic acids and derivatives |
---|
Sub Class | Amino acids, peptides, and analogues |
---|
Direct Parent | Alpha amino acids |
---|
Alternative Parents | |
---|
Substituents | - Alpha-amino acid
- Fatty acid
- Guanidine
- Amino acid
- Carboxylic acid
- Monocarboxylic acid or derivatives
- Organopnictogen compound
- Primary amine
- Organooxygen compound
- Organonitrogen compound
- Organic nitrogen compound
- Primary aliphatic amine
- Organic oxygen compound
- Carbonyl group
- Amine
- Hydrocarbon derivative
- Organic oxide
- Aliphatic acyclic compound
|
---|
Molecular Framework | Aliphatic acyclic compounds |
---|
External Descriptors | Not Available |
---|
Physical Properties |
---|
State | Not Available |
---|
Experimental Properties | Property | Value | Reference |
---|
Melting Point | Not Available | Not Available | Boiling Point | Not Available | Not Available | Water Solubility | Not Available | Not Available | LogP | Not Available | Not Available |
|
---|
Predicted Properties | |
---|
General References | - Almuhayawi MS, Hassan AHA, Al Jaouni SK, Alkhalifah DHM, Hozzein WN, Selim S, AbdElgawad H, Khamis G: Influence of elevated CO2 on nutritive value and health-promoting prospective of three genotypes of Alfalfa sprouts (Medicago Sativa). Food Chem. 2021 Mar 15;340:128147. doi: 10.1016/j.foodchem.2020.128147. Epub 2020 Sep 23. [PubMed:33032148 ]
- Dwarka D, Agoni C, Mellem JJ, Soliman ME, Baijnath H: Identification of potential SARS-CoV-2 inhibitors from South African medicinal plant extracts using molecular modelling approaches. S Afr J Bot. 2020 Sep;133:273-284. doi: 10.1016/j.sajb.2020.07.035. Epub 2020 Aug 19. [PubMed:32839635 ]
- Chiang Wong H, Gonzalez Guzman MDC, Gonzalez Saldana P: [Primary immune thrombocytopenia linked to the ingestion of guinea pigs (Cavia porcellus) causality or coincidence?]. Rev Fac Cien Med Univ Nac Cordoba. 2024 Jun 28;81(2):391-402. doi: 10.31053/1853.0605.v81.n2.44592. [PubMed:38941218 ]
- Chatterjee S, Fellner M, Rankin J, Thomas MG, J S Rifayee SB, Christov CZ, Hu J, Hausinger RP: Structural, Spectroscopic, and Computational Insights from Canavanine-Bound and Two Catalytically Compromised Variants of the Ethylene-Forming Enzyme. Biochemistry. 2024 Apr 16;63(8):1038-1050. doi: 10.1021/acs.biochem.4c00031. Epub 2024 Apr 5. [PubMed:38577885 ]
- Bhowal P, Roy B, Ganguli S, Igloi GL, Banerjee R: Elucidating the structure-function attributes of a trypanosomal arginyl-tRNA synthetase. Mol Biochem Parasitol. 2023 Dec;256:111597. doi: 10.1016/j.molbiopara.2023.111597. Epub 2023 Oct 16. [PubMed:37852416 ]
- Artiles-Ortega E, de la Fe-Rodriguez PY, Reguera-Barreto B, Lima-Orozco R, Fievez V: In vitro rumen degradability of tropical legumes and their secondary metabolites depends on inoculum source. Trop Anim Health Prod. 2022 Sep 29;54(5):330. doi: 10.1007/s11250-022-03327-z. [PubMed:36173493 ]
- Mardani-Korrani H, Nakayasu M, Yamazaki S, Aoki Y, Kaida R, Motobayashi T, Kobayashi M, Ohkama-Ohtsu N, Oikawa Y, Sugiyama A, Fujii Y: L-Canavanine, a Root Exudate From Hairy Vetch (Vicia villosa) Drastically Affecting the Soil Microbial Community and Metabolite Pathways. Front Microbiol. 2021 Sep 27;12:701796. doi: 10.3389/fmicb.2021.701796. eCollection 2021. [PubMed:34646244 ]
- Authors unspecified: Alfalfa.. 2006. [PubMed:30000890 ]
- Ntuli SSBN, Gelderblom WCA, Katerere DR: The mutagenic and antimutagenic activity of Sutherlandia frutescens extracts and marker compounds. BMC Complement Altern Med. 2018 Mar 15;18(1):93. doi: 10.1186/s12906-018-2159-z. [PubMed:29544492 ]
- Onselen RV, Downing S, Kemp G, Downing T: Investigating beta-N-Methylamino-l-alanine Misincorporation in Human Cell Cultures: A Comparative Study with Known Amino Acid Analogues. Toxins (Basel). 2017 Dec 14;9(12):400. doi: 10.3390/toxins9120400. [PubMed:29240689 ]
|
---|