Record Information |
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Version | 2.0 |
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Created at | 2024-09-09 23:12:45 UTC |
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Updated at | 2024-09-09 23:12:45 UTC |
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NP-MRD ID | NP0334334 |
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Secondary Accession Numbers | None |
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Natural Product Identification |
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Common Name | 4-hydroxybutanoate |
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Description | Gamma hydroxybutyric acid, also known as 4-hydroxybutanoic acid or ghb, is a member of the class of compounds known as hydroxy fatty acids. Hydroxy fatty acids are fatty acids in which the chain bears a hydroxyl group. Gamma hydroxybutyric acid is soluble (in water) and a weakly acidic compound (based on its pKa). Gamma hydroxybutyric acid can be found in a number of food items such as cauliflower, burdock, acorn, and mountain yam, which makes gamma hydroxybutyric acid a potential biomarker for the consumption of these food products. Gamma hydroxybutyric acid can be found primarily in blood and urine. Gamma hydroxybutyric acid is a drug which is used as a general anesthetic, to treat conditions such as insomnia, clinical depression, narcolepsy, and alcoholism, and to improve athletic performance. At higher doses, GHB may induce nausea, dizziness, drowsiness, agitation, visual disturbances, depressed breathing, amnesia, unconsciousness, and death (DrugBank). |
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Structure | InChI=1S/C4H8O3/c5-3-1-2-4(6)7/h5H,1-3H2,(H,6,7)/p-1 |
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Synonyms | Value | Source |
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4-Hydroxybutanoate | ChEBI | gamma-Hydroxybutyrate | ChEBI | GHB | ChEBI | 4-Hydroxybutanoic acid | Generator | g-Hydroxybutyrate | Generator | g-Hydroxybutyric acid | Generator | Γ-hydroxybutyrate | Generator | Γ-hydroxybutyric acid | Generator | g Hydroxybutyrate | Generator | g Hydroxybutyric acid | Generator | gamma Hydroxybutyrate | Generator, MeSH | γ hydroxybutyrate | Generator | γ hydroxybutyric acid | Generator | gamma-Hydroxybutyric acid | Generator | 4-Hydroxy-butanoic acid | HMDB | 4-Hydroxybutyric acid | HMDB | Juice | HMDB | Liquid ecstasy | HMDB | Sodium oxybate | HMDB, MeSH | 4 Hydroxybutyrate sodium | MeSH | Sodium gamma hydroxybutyrate | MeSH | Sodium gamma-hydroxybutyrate | MeSH | Oxybutyrate, sodium | MeSH | Sodium oxybutyrate | MeSH | Somsanit | MeSH | 4-Hydroxybutyrate sodium | MeSH | Oxybate sodium | MeSH | Oxybate, sodium | MeSH | Xyrem | MeSH |
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Chemical Formula | C4H7O3 |
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Average Mass | 103.0966 Da |
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Monoisotopic Mass | 103.03952 Da |
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IUPAC Name | 4-hydroxybutanoate |
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Traditional Name | gamma-hydroxybutyrate |
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CAS Registry Number | Not Available |
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SMILES | OCCCC([O-])=O |
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InChI Identifier | InChI=1S/C4H8O3/c5-3-1-2-4(6)7/h5H,1-3H2,(H,6,7)/p-1 |
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InChI Key | SJZRECIVHVDYJC-UHFFFAOYSA-M |
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Experimental Spectra |
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| Not Available | Predicted Spectra |
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| Not Available | Chemical Shift Submissions |
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| Not Available | Species |
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Species of Origin | Not Available |
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Chemical Taxonomy |
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Description | Belongs to the class of organic compounds known as hydroxy fatty acids. These are fatty acids in which the chain bears a hydroxyl group. |
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Kingdom | Organic compounds |
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Super Class | Lipids and lipid-like molecules |
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Class | Fatty Acyls |
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Sub Class | Fatty acids and conjugates |
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Direct Parent | Hydroxy fatty acids |
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Alternative Parents | |
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Substituents | - Short-chain hydroxy acid
- Hydroxy fatty acid
- Straight chain fatty acid
- Monocarboxylic acid or derivatives
- Carboxylic acid
- Carboxylic acid derivative
- Organic oxygen compound
- Organic oxide
- Hydrocarbon derivative
- Primary alcohol
- Organooxygen compound
- Carbonyl group
- Alcohol
- Organic anion
- Aliphatic acyclic compound
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Molecular Framework | Aliphatic acyclic compounds |
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External Descriptors | |
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Physical Properties |
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State | Not Available |
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Experimental Properties | Property | Value | Reference |
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Melting Point | Not Available | Not Available | Boiling Point | Not Available | Not Available | Water Solubility | Not Available | Not Available | LogP | Not Available | Not Available |
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Predicted Properties | |
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