NP-MRD: Showing NP-Card for Anthoteibinene F (NP0332688)

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Record Information

Version

2.0

Created at

2024-03-21 13:53:37 UTC

Updated at

2024-09-03 04:20:00 UTC

NP-MRD ID

NP0332688

Natural Product DOI

https://doi.org/10.57994/1948

Secondary Accession Numbers

None

Natural Product Identification

Common Name

Anthoteibinene F

Description

Anthoteibinene F belongs to the class of organic compounds known as terpene lactones. These are prenol lipids containing a lactone ring. Based on a literature review very few articles have been published on Anthoteibinene F.

Structure

MOL SDF PDB SMILES InChI


  Mrv2104 03212413532D          

 19 21  0  0  1  0            999 V2000
    2.1001   -2.4671    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4326   -1.9821    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6790   -2.3177    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5189   -1.1617    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.8514   -0.6767    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9377    0.1437    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6913    0.4793    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9463    1.2639    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7713    1.2639    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.4614    1.9314    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.3588   -0.0056    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2725   -0.8261    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.3019   -1.6506    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.1987   -1.1617    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.8661   -0.6767    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.6198   -1.0123    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.7799    0.1437    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.0262    0.4793    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.6393    1.0313    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  4  2  1  1  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  8 10  2  0  0  0  0
  7 11  2  0  0  0  0
 12 11  1  0  0  0  0
  4 12  1  0  0  0  0
 12 13  1  1  0  0  0
 12 14  1  0  0  0  0
 14 15  2  0  0  0  0
 15 16  1  0  0  0  0
 15 17  1  0  0  0  0
 18 17  1  0  0  0  0
 18 11  1  0  0  0  0
 18  9  1  0  0  0  0
 18 19  1  1  0  0  0
M  END
> <DATABASE_ID>
NP0332688

> <DATABASE_NAME>
NP-MRD

> <SMILES>
[H][C@@]12C=C(C)C[C@@]3(O)OC(=O)C(CC[C@@H]1C(C)C)=C23

> <INCHI_IDENTIFIER>
InChI=1S/C15H20O3/c1-8(2)10-4-5-11-13-12(10)6-9(3)7-15(13,17)18-14(11)16/h6,8,10,12,17H,4-5,7H2,1-3H3/t10-,12-,15-/m1/s1

> <INCHI_KEY>
DCFMBIFCAAFNLH-IXPVHAAZSA-N

> <FORMULA>
C15H20O3

> <MOLECULAR_WEIGHT>
248.322

> <EXACT_MASS>
248.141244504

> <JCHEM_ACCEPTOR_COUNT>
2

> <JCHEM_ATOM_COUNT>
38

> <JCHEM_AVERAGE_POLARIZABILITY>
27.327923987479956

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
1

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
(1R,7R,8S)-1-hydroxy-10-methyl-7-(propan-2-yl)-2-oxatricyclo[6.3.1.0^{4,12}]dodeca-4(12),9-dien-3-one

> <JCHEM_LOGP>
2.8449903553333336

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
3

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA_STRONGEST_ACIDIC>
11.175300259072907

> <JCHEM_PKA_STRONGEST_BASIC>
-4.471723666681509

> <JCHEM_POLAR_SURFACE_AREA>
46.53

> <JCHEM_REFRACTIVITY>
69.65

> <JCHEM_ROTATABLE_BOND_COUNT>
1

> <JCHEM_RULE_OF_FIVE>
1

> <JCHEM_TRADITIONAL_IUPAC>
(1R,7R,8S)-1-hydroxy-7-isopropyl-10-methyl-2-oxatricyclo[6.3.1.0^{4,12}]dodeca-4(12),9-dien-3-one

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 21-MAR-24   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   21-MAR-24         0                                  
HETATM    1  C   UNK     0       3.920  -4.605   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       2.674  -3.700   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       1.267  -4.326   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       2.835  -2.168   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       1.589  -1.263   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       1.750   0.268   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       3.157   0.895   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       3.633   2.359   0.000  0.00  0.00           C+0
HETATM    9  O   UNK     0       5.173   2.359   0.000  0.00  0.00           O+0
HETATM   10  O   UNK     0       2.728   3.605   0.000  0.00  0.00           O+0
HETATM   11  C   UNK     0       4.403  -0.010   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       4.242  -1.542   0.000  0.00  0.00           C+0
HETATM   13  H   UNK     0       4.297  -3.081   0.000  0.00  0.00           H+0
HETATM   14  C   UNK     0       5.971  -2.168   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       7.217  -1.263   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       8.624  -1.890   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       7.056   0.268   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       5.649   0.895   0.000  0.00  0.00           C+0
HETATM   19  O   UNK     0       6.793   1.925   0.000  0.00  0.00           O+0
CONECT    1    2                                                            
CONECT    2    1    3    4                                                  
CONECT    3    2                                                            
CONECT    4    2    5   12                                                  
CONECT    5    4    6                                                       
CONECT    6    5    7                                                       
CONECT    7    6    8   11                                                  
CONECT    8    7    9   10                                                  
CONECT    9    8   18                                                       
CONECT   10    8                                                            
CONECT   11    7   12   18                                                  
CONECT   12   11    4   13   14                                             
CONECT   13   12                                                            
CONECT   14   12   15                                                       
CONECT   15   14   16   17                                                  
CONECT   16   15                                                            
CONECT   17   15   18                                                       
CONECT   18   17   11    9   19                                             
CONECT   19   18                                                            
MASTER        0    0    0    0    0    0    0    0   19    0   42    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₁₅H₂₀O₃

Average Mass

248.3220 Da

Monoisotopic Mass

248.14124 Da

IUPAC Name

(1R,7R,8S)-1-hydroxy-10-methyl-7-(propan-2-yl)-2-oxatricyclo[6.3.1.0^{4,12}]dodeca-4(12),9-dien-3-one

Traditional Name

(1R,7R,8S)-1-hydroxy-7-isopropyl-10-methyl-2-oxatricyclo[6.3.1.0^{4,12}]dodeca-4(12),9-dien-3-one

CAS Registry Number

Not Available

SMILES

[H][C@@]12C=C(C)C[C@@]3(O)OC(=O)C(CC[C@@H]1C(C)C)=C23

InChI Identifier

InChI=1S/C15H20O3/c1-8(2)10-4-5-11-13-12(10)6-9(3)7-15(13,17)18-14(11)16/h6,8,10,12,17H,4-5,7H2,1-3H3/t10-,12-,15-/m1/s1

InChI Key

DCFMBIFCAAFNLH-IXPVHAAZSA-N

Experimental Spectra

Spectrum Type	Description	Depositor Email	Depositor Organization	Depositor	Deposition Date	View
1D_ NMR	¹H NMR Spectrum (1D, 600 MHz, CDCl3, experimental)	Not Available	University of South Florida	Bill J. Baker	2024-03-21	View Spectrum
NOESY NMR	[¹H, ¹H] NMR Spectrum (2D, 600 MHz, CDCl3, experimental)	Not Available	University of South Florida	Bill J. Baker	2024-03-21	View Spectrum
HMBC NMR	[¹H, ¹³C] NMR Spectrum (2D, 400 MHz, CDCl3, experimental)	Not Available	University of South Florida	Bill J. Baker	2024-03-21	View Spectrum
HSQC NMR	[¹H, ¹³C] NMR Spectrum (2D, 400 MHz, CDCl3, experimental)	Not Available	University of South Florida	Bill J. Baker	2024-03-21	View Spectrum
COSY NMR	[¹H, ¹H] NMR Spectrum (2D, 400 MHz, CDCl3, experimental)	Not Available	University of South Florida	Bill J. Baker	2024-03-21	View Spectrum
1D_ NMR	¹³C NMR Spectrum (1D, 101 MHz, CDCl3, experimental)	Not Available	University of South Florida	Bill J. Baker	2024-03-21	View Spectrum

Predicted Spectra

Not Available

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Anthothela grandiflora		Not Available

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as terpene lactones. These are prenol lipids containing a lactone ring.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Prenol lipids

Sub Class

Terpene lactones

Direct Parent

Terpene lactones

Alternative Parents

Substituents

Terpene lactone
Farsesane sesquiterpenoid
Sesquiterpenoid
Fatty alcohol ester
Fatty acid ester
Fatty acyl
Hemiketal
2-furanone
Alpha,beta-unsaturated carboxylic ester
Enoate ester
Dihydrofuran
Lactone
Carboxylic acid ester
Oxacycle
Organoheterocyclic compound
Monocarboxylic acid or derivatives
Carboxylic acid derivative
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Aliphatic heteropolycyclic compound

Molecular Framework

Aliphatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	2.84	ChemAxon
pKa (Strongest Acidic)	11.18	ChemAxon
pKa (Strongest Basic)	-4.5	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	2	ChemAxon
Hydrogen Donor Count	1	ChemAxon
Polar Surface Area	46.53 Å²	ChemAxon
Rotatable Bond Count	1	ChemAxon
Refractivity	69.65 m³·mol⁻¹	ChemAxon
Polarizability	27.33 Å³	ChemAxon
Number of Rings	3	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

Not Available

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

Not Available

Showing NP-Card for Anthoteibinene F (NP0332688)

MOL for NP0332688 (Anthoteibinene F)

3D MOL for NP0332688 (Anthoteibinene F)

3D SDF for NP0332688 (Anthoteibinene F)

3D-SDF for NP0332688 (Anthoteibinene F)

PDB for NP0332688 (Anthoteibinene F)

3D PDB for NP0332688 (Anthoteibinene F)

SMILES for NP0332688 (Anthoteibinene F)

INCHI for NP0332688 (Anthoteibinene F)

Structure for NP0332688 (Anthoteibinene F)

3D Structure for NP0332688 (Anthoteibinene F)