Np mrd loader

Record Information
Version1.0
Created at2022-11-21 23:29:48 UTC
Updated at2024-04-19 09:32:39 UTC
NP-MRD IDNP0331186
Secondary Accession NumbersNone
Natural Product Identification
Common NameTalaropeptide B
DescriptionTalaropeptide B belongs to the class of organic compounds known as hybrid peptides. Hybrid peptides are compounds containing at least two different types of amino acids (alpha, beta, gamma, delta) linked to each other through a peptide bond. It was first documented in 2023 (PMID: 37078450). Based on a literature review a significant number of articles have been published on Talaropeptide B (PMID: 37078444) (PMID: 37078443) (PMID: 37078154) (PMID: 37078114) (PMID: 37079959) (PMID: 37079958).
Structure
Thumb
SynonymsNot Available
Chemical FormulaC70H120N12O14
Average Mass1353.8000 Da
Monoisotopic Mass1352.90470 Da
IUPAC NameNot Available
Traditional NameNot Available
CAS Registry NumberNot Available
SMILES
CC[C@H](C)[C@H](N(C)C(=O)[C@H](CC1=CC=CC=C1)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@@H]1CCCN1C(=O)[C@H](C(C)C)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C(=O)[C@H](C)NC)C(C)C)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O
InChI Identifier
InChI=1S/C70H120N12O14/c1-26-44(16)58(62(87)72-48(70(95)96)35-37(2)3)81(25)65(90)50(36-47-31-28-27-29-32-47)76(20)67(92)55(41(10)11)80(24)68(93)56(42(12)13)78(22)64(89)49-33-30-34-82(49)69(94)57(43(14)15)79(23)66(91)52(39(6)7)74-60(85)53(46(18)83)75-59(84)51(38(4)5)73-61(86)54(40(8)9)77(21)63(88)45(17)71-19/h27-29,31-32,37-46,48-58,71,83H,26,30,33-36H2,1-25H3,(H,72,87)(H,73,86)(H,74,85)(H,75,84)(H,95,96)/t44-,45-,46+,48-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-/m0/s1
InChI KeyCWUNJRMISPNJFK-DTNNBZDOSA-N
Experimental Spectra
Spectrum TypeDescriptionDepositor EmailDepositor OrganizationDepositorDeposition DateView
ROESY NMR[1H, 1H] NMR Spectrum (2D, 600 MHz, CD3OD, experimental)z.khalil@uq.edu.auNot AvailableNot Available2022-11-21View Spectrum
HMBC NMR[1H, 13C] NMR Spectrum (2D, 600 MHz, CD3OD, experimental)z.khalil@uq.edu.auNot AvailableNot Available2022-11-21View Spectrum
1D NMR[13C, ] NMR Spectrum (2D, 151 MHz, CD3OD, experimental)z.khalil@uq.edu.auNot AvailableNot Available2022-11-21View Spectrum
1D NMR[1H, ] NMR Spectrum (2D, 600 MHz, CD3OD, experimental)z.khalil@uq.edu.auNot AvailableNot Available2022-11-21View Spectrum
1D NMR1H NMR Spectrum (1D, 600.13 MHz, CD3OD, simulated)Wishart LabWishart LabDavid Wishart2021-06-20View Spectrum
1D NMR13C NMR Spectrum (1D, 150.92 MHz, CD3OD, simulated)Wishart LabWishart LabDavid Wishart2021-06-20View Spectrum
Predicted Spectra
Not Available
Chemical Shift Submissions
Not Available
Species
Species of OriginNot Available
Chemical Taxonomy
Description Belongs to the class of organic compounds known as hybrid peptides. Hybrid peptides are compounds containing at least two different types of amino acids (alpha, beta, gamma, delta) linked to each other through a peptide bond.
KingdomOrganic compounds
Super ClassOrganic acids and derivatives
ClassPeptidomimetics
Sub ClassHybrid peptides
Direct ParentHybrid peptides
Alternative Parents
Substituents
  • Hybrid peptide
  • Phenylalanine or derivatives
  • Leucine or derivatives
  • Valine or derivatives
  • Proline or derivatives
  • N-acyl-alpha amino acid or derivatives
  • N-acyl-alpha-amino acid
  • Alpha-amino acid amide
  • Alanine or derivatives
  • Amphetamine or derivatives
  • Alpha-amino acid or derivatives
  • Pyrrolidine-2-carboxamide
  • Pyrrolidine carboxylic acid or derivatives
  • N-acylpyrrolidine
  • Benzenoid
  • N-acyl-amine
  • Monocyclic benzene moiety
  • Tertiary carboxylic acid amide
  • Pyrrolidine
  • Amino acid
  • Secondary alcohol
  • Carboxamide group
  • Amino acid or derivatives
  • Azacycle
  • Organoheterocyclic compound
  • Organic 1,3-dipolar compound
  • Propargyl-type 1,3-dipolar organic compound
  • Secondary amine
  • Monocarboxylic acid or derivatives
  • Secondary aliphatic amine
  • Carboxylic acid
  • Carboxylic acid derivative
  • Carboximidic acid derivative
  • Carboximidic acid
  • Organic nitrogen compound
  • Organic oxygen compound
  • Organopnictogen compound
  • Organic oxide
  • Hydrocarbon derivative
  • Organooxygen compound
  • Organonitrogen compound
  • Carbonyl group
  • Amine
  • Alcohol
  • Aromatic heteromonocyclic compound
Molecular FrameworkAromatic heteromonocyclic compounds
External DescriptorsNot Available
Physical Properties
StateNot Available
Experimental Properties
PropertyValueReference
Melting PointNot AvailableNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogPNot AvailableNot Available
Predicted Properties
PropertyValueSource
HMDB IDNot Available
DrugBank IDNot Available
Phenol Explorer Compound IDNot Available
FoodDB IDNot Available
KNApSAcK IDNot Available
Chemspider ID71048870
KEGG Compound IDNot Available
BioCyc IDNot Available
BiGG IDNot Available
Wikipedia LinkNot Available
METLIN IDNot Available
PubChem Compound156581781
PDB IDNot Available
ChEBI IDNot Available
Good Scents IDNot Available
References
General References
  1. Russi AE, Shivakumar P, Luo Z, Bezerra J: Plasticity between ILC2 subsets and amphiregulin expression regulate epithelial repair in biliary atresia. Hepatology. 2023 Apr 21. doi: 10.1097/HEP.0000000000000418. [PubMed:37078450 ]
  2. Hlady RA, Robertson KD: Epigenetic memory of environmental exposures as a mediator of liver disease. Hepatology. 2023 Apr 21. doi: 10.1097/HEP.0000000000000414. [PubMed:37078444 ]
  3. Ufere NN: Home is where the liver is?: moving beyond readmissions to time at home as a patient-centered and pragmatic quality measure in cirrhosis care. Hepatology. 2023 Apr 21. doi: 10.1097/HEP.0000000000000415. [PubMed:37078443 ]
  4. Arnon R, Rubinov A: [[PTOSIS AS A SIGN OF A SYSTEMIC DISEASE]]. Harefuah. 2023 Feb;162(2):119-121. [PubMed:37078154 ]
  5. Shemesh N, Olshaker H: [[A MULTICENTER SPANISH STUDY OF ATROPINE 0.01% IN CHILDHOOD MYOPIA PROGRESSION]]. Harefuah. 2023 Feb;162(2):116-118. [PubMed:37078114 ]
  6. Gonzalez Muriel RM, Garcia Rabanal D, Ramos Pascua LR: [Incidental finding in mechanical gonalgia in a patient with a history of breast cancer]. Semergen. 2023 Jul-Aug;49(5):101978. doi: 10.1016/j.semerg.2023.101978. Epub 2023 Apr 18. [PubMed:37079959 ]
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  8. Samboni-Mendez M, Benavides-Ruiz MM, Piamba-Valencia AM, Sanchez-Duque JA: [Subcutaneous analgesia in elderly palliative home care]. Semergen. 2023 Jul-Aug;49(5):101975. doi: 10.1016/j.semerg.2023.101975. Epub 2023 Apr 18. [PubMed:37079957 ]
  9. K B C, R H, R A, G JJB, J P D, Banjara SK, M A, K PR, B N, M SP: Macronutrient composition of term and preterm human milk of different socio economic groups. Prostaglandins Leukot Essent Fatty Acids. 2023 May;192:102571. doi: 10.1016/j.plefa.2023.102571. Epub 2023 Mar 30. [PubMed:37079956 ]
  10. Jyothi VGSS, Veerabomma H, Tryphena KP, Khatri DK, Singh SB, Madan J: Acute and sub-acute dermal toxicity of meloxicam emulgel: Analysis of biochemical, hematological, histopathological and immunohistochemical expression. Biochem Biophys Res Commun. 2023 Jun 11;660:88-95. doi: 10.1016/j.bbrc.2023.04.001. Epub 2023 Apr 11. [PubMed:37079955 ]
  11. Akhlaghpour H: Erratum to "An RNA-based theory of natural universal computation" [J. Theor. Biol. 537 (2022) 110984]. J Theor Biol. 2023 Jun 7;566:111481. doi: 10.1016/j.jtbi.2023.111481. Epub 2023 Apr 18. [PubMed:37079954 ]
  12. Pelletier F, Torres A, Meloche-Dumas L, Guerard-Poirier N, Kaviani A, Kapralos B, Mercier F, Dubrowski A, Patocskai E: The Role of Collaborative Observational Practice and Feedback-Discourse to Promote Remote Acquisition of Technical Surgical Skills. J Surg Res. 2023 Aug;288:372-382. doi: 10.1016/j.jss.2023.02.006. Epub 2023 Apr 18. [PubMed:37079953 ]
  13. Hryciuk MM, Schroter F, Hennicke L, Braun BC: Spheroid formation and luteinization of granulosa cells of felids in a long-term 3D culture. Differentiation. 2023 May-Jun;131:38-48. doi: 10.1016/j.diff.2023.03.002. Epub 2023 Apr 6. [PubMed:37079952 ]
  14. Chan NY, Wu WJ, Chan JWY, Chan KCC, Li AM, Chan SSM, Hau KT, Wing YK: Sleep and academic performance among students in Hong Kong: Curvilinear relationship suggesting an optimal amount of sleep. Sleep Med. 2023 Jun;106:97-105. doi: 10.1016/j.sleep.2023.04.001. Epub 2023 Apr 6. [PubMed:37079951 ]
  15. Toss A, Moscetti L: Are you treating ypN0 patient with adjuvant abemaciclib? ESMO Open. 2023 Jun;8(3):101217. doi: 10.1016/j.esmoop.2023.101217. Epub 2023 Apr 19. [PubMed:37079950 ]
  16. Gracia-Sanchez A, Lopez-Pineda A, Lazaro-Martinez JL, Perez A, Pomares-Gomez FJ, Fernandez-Seguin LM, Gil-Guillen VF, Chicharro-Luna E: Consensus-based recommendations on physical activity and exercise in patients with diabetes at risk of foot ulcerations: a Delphi study. Braz J Phys Ther. 2023 Mar-Apr;27(2):100500. doi: 10.1016/j.bjpt.2023.100500. Epub 2023 Apr 6. [PubMed:37079949 ]
  17. Tabata F, Wada Y, Shibasaki T, Kawakami S, Inubashiri M, Hosaka M, Noshiro K, Umazume T, Miyaji K: A lower ratio of reduced to total albumin in serum is associated with protein nutritional status of pregnant women in Japan. Nutr Res. 2023 Jun;114:1-12. doi: 10.1016/j.nutres.2023.03.006. Epub 2023 Mar 23. [PubMed:37079948 ]
  18. Dean B, Haroutunian V, Scarr E: Lower levels of cortical [(3)H]pirenzepine binding to postmortem tissue defines a sub-group of older people with schizophrenia with less severe cognitive deficits. Schizophr Res. 2023 May;255:274-282. doi: 10.1016/j.schres.2023.03.035. Epub 2023 Apr 19. [PubMed:37079947 ]
  19. Buma S, Banks L, Onwuka A, Althubaiti A, Wiet G: Maternal infant bonding in tracheostomy dependent infants: A cross sectional study. Int J Pediatr Otorhinolaryngol. 2023 May;168:111549. doi: 10.1016/j.ijporl.2023.111549. Epub 2023 Apr 7. [PubMed:37079946 ]
  20. Hintze JM, Afshar S, Taghinia A, Labow B, Green M, Robson CD, Marcus K, Mack J, Perez-Atayde A, Rahbar R: A multi-disciplinary team approach to pediatric malignant mandibular tumors. Int J Pediatr Otorhinolaryngol. 2023 May;168:111547. doi: 10.1016/j.ijporl.2023.111547. Epub 2023 Apr 15. [PubMed:37079945 ]