NP-MRD: Showing NP-Card for methyl 2-[(2r,4ar,8ar)-8-(hydroxymethyl)-4a-methyl-2,3,4,5,6,8a-hexahydro-1h-naphthalen-2-yl]prop-2-enoate (NP0331063)

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Record Information

Version

1.0

Created at

2022-09-12 17:02:26 UTC

Updated at

2022-09-12 17:02:26 UTC

NP-MRD ID

NP0331063

Secondary Accession Numbers

None

Natural Product Identification

Common Name

methyl 2-[(2r,4ar,8ar)-8-(hydroxymethyl)-4a-methyl-2,3,4,5,6,8a-hexahydro-1h-naphthalen-2-yl]prop-2-enoate

Description

Methyl 2-[(2R,4aR,8aR)-8-(hydroxymethyl)-4a-methyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-2-yl]prop-2-enoate belongs to the class of organic compounds known as eudesmane, isoeudesmane or cycloeudesmane sesquiterpenoids. These are sesquiterpenoids with a structure based on the eudesmane skeleton. methyl 2-[(2r,4ar,8ar)-8-(hydroxymethyl)-4a-methyl-2,3,4,5,6,8a-hexahydro-1h-naphthalen-2-yl]prop-2-enoate is found in Cassinia uncata. It was first documented in 1993 (PMID: 36137062). Based on a literature review a significant number of articles have been published on methyl 2-[(2R,4aR,8aR)-8-(hydroxymethyl)-4a-methyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-2-yl]prop-2-enoate (PMID: 36137063) (PMID: 36137748) (PMID: 36137747) (PMID: 36137746) (PMID: 36137745) (PMID: 36137744).

Structure

MOL 3D MOL SDF PDB SMILES InChI

     RDKit          3D

 43 44  0  0  0  0  0  0  0  0999 V2000
    3.0224    0.2658    2.1155 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5488   -0.0552    0.9415 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3068   -0.9508    0.0919 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8608   -1.2642   -1.0366 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.5094   -1.4647    0.5014 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.3108   -2.3375   -0.2533 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2712    0.4801    0.4837 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.6393    1.4439    1.4572 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5167    2.1211    0.7842 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5057    1.1890    0.1664 C   0  0  1  0  0  0  0  0  0  0  0  0
   -2.3917    0.6535    1.2820 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4028    1.9312   -0.7868 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6511    1.2166   -2.0770 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8131   -0.2724   -1.8805 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8717   -0.8350   -1.1158 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9199   -2.2903   -0.8480 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9961   -2.8966   -1.4637 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8431    0.0708   -0.5946 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.2370   -0.5994    0.1881 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9596   -0.1281    2.4461 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.4751    0.9257    2.7554 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.3385   -1.9812   -1.3213 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.3613   -2.2229    0.1062 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.0261   -3.3917   -0.1791 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.3797    1.0601   -0.4812 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.4118    2.2503    1.6313 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.3807    0.9798    2.4205 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1003    2.7952    0.0018 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0360    2.7380    1.5483 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3733    0.3811    0.8425 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5810    1.5196    1.9648 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9213   -0.1304    1.8714 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9479    2.9169   -1.0137 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4046    2.1696   -0.3352 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8692    1.4332   -2.8377 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6123    1.5673   -2.5085 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6106   -0.8299   -2.3144 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9921   -2.5141    0.2484 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9719   -2.7675   -1.1954 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8258   -2.8553   -0.9344 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3498    0.5533   -1.4852 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1609   -0.9044    1.1923 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.6299   -1.4406   -0.3784 H   0  0  0  0  0  0  0  0  0  0  0  0
  6  5  1  0
  5  3  1  0
  3  4  2  0
  3  2  1  0
  2  1  2  3
  2  7  1  0
  7  8  1  0
  8  9  1  0
  9 10  1  0
 10 11  1  1
 10 12  1  0
 12 13  1  0
 13 14  1  0
 14 15  2  0
 15 16  1  0
 16 17  1  0
 15 18  1  0
 18 19  1  0
 19  7  1  0
 18 10  1  0
  6 22  1  0
  6 23  1  0
  6 24  1  0
  1 20  1  0
  1 21  1  0
  7 25  1  6
  8 26  1  0
  8 27  1  0
  9 28  1  0
  9 29  1  0
 11 30  1  0
 11 31  1  0
 11 32  1  0
 12 33  1  0
 12 34  1  0
 13 35  1  0
 13 36  1  0
 14 37  1  0
 16 38  1  0
 16 39  1  0
 17 40  1  0
 18 41  1  6
 19 42  1  0
 19 43  1  0
M  END


  Mrv1652309122219022D          

 19 20  0  0  1  0            999 V2000
   -0.7145   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -3.7125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -1.2375    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -0.4125    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.1434    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -1.2375    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.4289   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  3  5  1  0  0  0  0
  5  6  1  0  0  0  0
  7  2  1  6  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  1  0  0  0  0
 10 11  1  6  0  0  0
 10 12  1  0  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  2  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 18 15  1  6  0  0  0
 10 18  1  0  0  0  0
 18 19  1  0  0  0  0
  7 19  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0331063

> <DATABASE_NAME>
NP-MRD

> <SMILES>
COC(=O)C(=C)[C@@H]1CC[C@@]2(C)CCC=C(CO)[C@@H]2C1

> <INCHI_IDENTIFIER>
InChI=1S/C16H24O3/c1-11(15(18)19-3)12-6-8-16(2)7-4-5-13(10-17)14(16)9-12/h5,12,14,17H,1,4,6-10H2,2-3H3/t12-,14+,16-/m1/s1

> <INCHI_KEY>
HAGXVVCJLUEXCT-IVMMDQJWSA-N

> <FORMULA>
C16H24O3

> <MOLECULAR_WEIGHT>
264.365

> <EXACT_MASS>
264.172544633

> <JCHEM_ACCEPTOR_COUNT>
2

> <JCHEM_ATOM_COUNT>
43

> <JCHEM_AVERAGE_POLARIZABILITY>
30.338712548686914

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
1

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
methyl 2-[(2R,4aR,8aR)-8-(hydroxymethyl)-4a-methyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-2-yl]prop-2-enoate

> <JCHEM_LOGP>
2.8094582233333343

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
2

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA_STRONGEST_ACIDIC>
17.182661810919026

> <JCHEM_PKA_STRONGEST_BASIC>
-1.8440993623179196

> <JCHEM_POLAR_SURFACE_AREA>
46.53

> <JCHEM_REFRACTIVITY>
75.7134

> <JCHEM_ROTATABLE_BOND_COUNT>
4

> <JCHEM_RULE_OF_FIVE>
1

> <JCHEM_TRADITIONAL_IUPAC>
methyl 2-[(2R,4aR,8aR)-8-(hydroxymethyl)-4a-methyl-2,3,4,5,6,8a-hexahydro-1H-naphthalen-2-yl]prop-2-enoate

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 12-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   12-SEP-22         0                                  
HETATM    1  C   UNK     0      -1.334  -2.310   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       0.000  -3.080   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       0.000  -4.620   0.000  0.00  0.00           C+0
HETATM    4  O   UNK     0       1.334  -5.390   0.000  0.00  0.00           O+0
HETATM    5  O   UNK     0      -1.334  -5.390   0.000  0.00  0.00           O+0
HETATM    6  C   UNK     0      -1.334  -6.930   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       1.334  -2.310   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       1.334  -0.770   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       2.667   0.000   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       4.001  -0.770   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       4.001   0.770   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       5.335   0.000   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       6.668  -0.770   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       6.668  -2.310   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       5.335  -3.080   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       5.335  -4.620   0.000  0.00  0.00           C+0
HETATM   17  O   UNK     0       4.001  -5.390   0.000  0.00  0.00           O+0
HETATM   18  C   UNK     0       4.001  -2.310   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       2.667  -3.080   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3    7                                                  
CONECT    3    2    4    5                                                  
CONECT    4    3                                                            
CONECT    5    3    6                                                       
CONECT    6    5                                                            
CONECT    7    2    8   19                                                  
CONECT    8    7    9                                                       
CONECT    9    8   10                                                       
CONECT   10    9   11   12   18                                             
CONECT   11   10                                                            
CONECT   12   10   13                                                       
CONECT   13   12   14                                                       
CONECT   14   13   15                                                       
CONECT   15   14   16   18                                                  
CONECT   16   15   17                                                       
CONECT   17   16                                                            
CONECT   18   15   10   19                                                  
CONECT   19   18    7                                                       
MASTER        0    0    0    0    0    0    0    0   19    0   40    0
END

View in JSmol

Synonyms

Value	Source
Methyl 2-[(2R,4ar,8ar)-8-(hydroxymethyl)-4a-methyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-2-yl]prop-2-enoic acid	Generator

Chemical Formula

C₁₆H₂₄O₃

Average Mass

264.3650 Da

Monoisotopic Mass

264.17254 Da

IUPAC Name

methyl 2-[(2R,4aR,8aR)-8-(hydroxymethyl)-4a-methyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-2-yl]prop-2-enoate

Traditional Name

methyl 2-[(2R,4aR,8aR)-8-(hydroxymethyl)-4a-methyl-2,3,4,5,6,8a-hexahydro-1H-naphthalen-2-yl]prop-2-enoate

CAS Registry Number

Not Available

SMILES

COC(=O)C(=C)[C@@H]1CC[C@@]2(C)CCC=C(CO)[C@@H]2C1

InChI Identifier

InChI=1S/C16H24O3/c1-11(15(18)19-3)12-6-8-16(2)7-4-5-13(10-17)14(16)9-12/h5,12,14,17H,1,4,6-10H2,2-3H3/t12-,14+,16-/m1/s1

InChI Key

HAGXVVCJLUEXCT-IVMMDQJWSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Cassinia uncata	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as eudesmane, isoeudesmane or cycloeudesmane sesquiterpenoids. These are sesquiterpenoids with a structure based on the eudesmane skeleton.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Prenol lipids

Sub Class

Sesquiterpenoids

Direct Parent

Eudesmane, isoeudesmane or cycloeudesmane sesquiterpenoids

Alternative Parents

Substituents

Eudesmane, isoeudesmane or cycloeudesmane sesquiterpenoid
Alpha,beta-unsaturated carboxylic ester
Enoate ester
Methyl ester
Carboxylic acid ester
Monocarboxylic acid or derivatives
Carboxylic acid derivative
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Primary alcohol
Organooxygen compound
Carbonyl group
Alcohol
Aliphatic homopolycyclic compound

Molecular Framework

Aliphatic homopolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	2.81	ChemAxon
pKa (Strongest Acidic)	17.18	ChemAxon
pKa (Strongest Basic)	-1.8	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	2	ChemAxon
Hydrogen Donor Count	1	ChemAxon
Polar Surface Area	46.53 Å²	ChemAxon
Rotatable Bond Count	4	ChemAxon
Refractivity	75.71 m³·mol⁻¹	ChemAxon
Polarizability	30.34 Å³	ChemAxon
Number of Rings	2	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

14707118

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

Salisbury L, Baraitser L: Depressing time: Waiting, melancholia, and the psychoanalytic practice of care. 2020. [PubMed:36137063 ]
Heimer G, Neuser S, Ben-Zeev B, Ebrahimi-Fakhari D: TECPR2-Related Hereditary Sensory and Autonomic Neuropathy with Intellectual Disability. 1993. [PubMed:36137062 ]
Tibbe D, Ferle P, Krisp C, Nampoothiri S, Mirzaa G, Assaf M, Parikh S, Kutsche K, Kreienkamp HJ: Regulation of Liprin-alpha phase separation by CASK is disrupted by a mutation in its CaM kinase domain. Life Sci Alliance. 2022 Sep 22;5(10). pii: 5/10/e202201512. doi: 10.26508/lsa.202201512. Print 2022 Oct. [PubMed:36137748 ]
Sengupta R, Mihelc EM, Angel S, Lanman JK, Kuhn RJ, Stahelin RV: Contribution of the Golgi apparatus in morphogenesis of a virus-induced cytopathic vacuolar system. Life Sci Alliance. 2022 Sep 22;5(10). pii: 5/10/e202000887. doi: 10.26508/lsa.202000887. Print 2022 Oct. [PubMed:36137747 ]
Cui Y, Peng S, Czaplicki L, Yang T: Protecting minors from tobacco products: public interest litigation enables enforcement in China. Tob Control. 2022 Sep 22. pii: tc-2022-057615. doi: 10.1136/tc-2022-057615. [PubMed:36137746 ]
Kneihsl M, Hinteregger N, Nistl O, Deutschmann H, Horner S, Poltrum B, Fandler-Hofler S, Hatab I, Haidegger M, Pinter D, Pichler A, Willeit K, Knoflach M, Enzinger C, Gattringer T: Post-reperfusion hyperperfusion after endovascular stroke treatment: a prospective comparative study of TCD versus MRI. J Neurointerv Surg. 2022 Sep 22. pii: jnis-2022-019213. doi: 10.1136/jnis-2022-019213. [PubMed:36137745 ]
Yusuf H, Rasheed A, Kim H, Conrad MB, Hetts SW: Identifying racial disparities in hereditary hemorrhagic telangiectasia. J Neurointerv Surg. 2022 Sep 22. pii: jnis-2022-019162. doi: 10.1136/jnis-2022-019162. [PubMed:36137744 ]
Housley SB, Monteiro A, Khawar WI, Donnelly BM, Lian MX, Fritz AG, Waqas M, Cappuzzo JM, Snyder KV, Siddiqui AH, Levy EI, Davies JM: Volumetric resolution of chronic subdural hematomas treated with surgical evacuation versus middle meningeal artery embolization during immediate, early, and late follow up: propensity-score matched cohorts. J Neurointerv Surg. 2022 Sep 22. pii: jnis-2022-019427. doi: 10.1136/jnis-2022-019427. [PubMed:36137743 ]
Thornhill MH, Crum A, Campbell R, Stone T, Lee EC, Bradburn M, Fibisan V, Dayer M, Prendergast BD, Lockhart P, Baddour L, Nicoll J: Temporal association between invasive procedures and infective endocarditis. Heart. 2022 Sep 22. pii: heartjnl-2022-321519. doi: 10.1136/heartjnl-2022-321519. [PubMed:36137742 ]
Plantone D, Locci S, Bergantini L, Manco C, Cortese R, Meocci M, Cavallaro D, d'Alessandro M, Bargagli E, De Stefano N: Brain neuronal and glial damage during acute COVID-19 infection in absence of clinical neurological manifestations. J Neurol Neurosurg Psychiatry. 2022 Sep 22. pii: jnnp-2022-329933. doi: 10.1136/jnnp-2022-329933. [PubMed:36137741 ]
LOTUS database [Link]

Showing NP-Card for methyl 2-[(2r,4ar,8ar)-8-(hydroxymethyl)-4a-methyl-2,3,4,5,6,8a-hexahydro-1h-naphthalen-2-yl]prop-2-enoate (NP0331063)

MOL for NP0331063 (methyl 2-[(2r,4ar,8ar)-8-(hydroxymethyl)-4a-methyl-2,3,4,5,6,8a-hexahydro-1h-naphthalen-2-yl]prop-2-enoate)

3D MOL for NP0331063 (methyl 2-[(2r,4ar,8ar)-8-(hydroxymethyl)-4a-methyl-2,3,4,5,6,8a-hexahydro-1h-naphthalen-2-yl]prop-2-enoate)

3D SDF for NP0331063 (methyl 2-[(2r,4ar,8ar)-8-(hydroxymethyl)-4a-methyl-2,3,4,5,6,8a-hexahydro-1h-naphthalen-2-yl]prop-2-enoate)

3D-SDF for NP0331063 (methyl 2-[(2r,4ar,8ar)-8-(hydroxymethyl)-4a-methyl-2,3,4,5,6,8a-hexahydro-1h-naphthalen-2-yl]prop-2-enoate)

PDB for NP0331063 (methyl 2-[(2r,4ar,8ar)-8-(hydroxymethyl)-4a-methyl-2,3,4,5,6,8a-hexahydro-1h-naphthalen-2-yl]prop-2-enoate)

3D PDB for NP0331063 (methyl 2-[(2r,4ar,8ar)-8-(hydroxymethyl)-4a-methyl-2,3,4,5,6,8a-hexahydro-1h-naphthalen-2-yl]prop-2-enoate)

SMILES for NP0331063 (methyl 2-[(2r,4ar,8ar)-8-(hydroxymethyl)-4a-methyl-2,3,4,5,6,8a-hexahydro-1h-naphthalen-2-yl]prop-2-enoate)

INCHI for NP0331063 (methyl 2-[(2r,4ar,8ar)-8-(hydroxymethyl)-4a-methyl-2,3,4,5,6,8a-hexahydro-1h-naphthalen-2-yl]prop-2-enoate)

Structure for NP0331063 (methyl 2-[(2r,4ar,8ar)-8-(hydroxymethyl)-4a-methyl-2,3,4,5,6,8a-hexahydro-1h-naphthalen-2-yl]prop-2-enoate)

3D Structure for NP0331063 (methyl 2-[(2r,4ar,8ar)-8-(hydroxymethyl)-4a-methyl-2,3,4,5,6,8a-hexahydro-1h-naphthalen-2-yl]prop-2-enoate)