NP-MRD: Showing NP-Card for prosopinine (NP0328561)

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Record Information

Version

1.0

Created at

2022-09-12 12:08:41 UTC

Updated at

2022-09-12 12:08:41 UTC

NP-MRD ID

NP0328561

Secondary Accession Numbers

None

Natural Product Identification

Common Name

prosopinine

Description

Prosopinine belongs to the class of organic compounds known as alkaloids and derivatives. These are naturally occurring chemical compounds that contain mostly basic nitrogen atoms. This group also includes some related compounds with neutral and even weakly acidic properties. Also some synthetic compounds of similar structure are attributed to alkaloids. In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen, sulfur and more rarely other elements such as chlorine, bromine, and phosphorus. Thus, prosopinine is considered to be a sphingoid base. Prosopinine is a secondary metabolite. Secondary metabolites are metabolically or physiologically non-essential metabolites that may serve a role as defense or signalling molecules. In some cases they are simply molecules that arise from the incomplete metabolism of other secondary metabolites. prosopinine is found in Prosopis africana. It was first documented in 2009 (PMID: 19731272). Based on a literature review a significant number of articles have been published on prosopinine (PMID: 36130844) (PMID: 36130843) (PMID: 36130842) (PMID: 36130841) (PMID: 36130840) (PMID: 36005538).

Structure

MOL 3D MOL SDF PDB SMILES InChI

     RDKit          3D

 53 53  0  0  0  0  0  0  0  0999 V2000
    7.3936    1.0188    0.5918 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9226    0.8139    0.1188 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7387   -0.6483   -0.0878 C   0  0  2  0  0  0  0  0  0  0  0  0
    6.7533   -0.9856   -1.0689 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.4916   -1.1477   -0.6857 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1754   -0.9210   -0.0706 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6487    0.4470    0.0671 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2857    0.4103    0.7418 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3005   -0.3853   -0.0587 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0230   -0.2936    0.7262 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1068   -1.0523    0.0319 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3782   -0.9545    0.8343 C   0  0  2  0  0  0  0  0  0  0  0  0
   -4.4526   -1.7361    0.1072 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9314   -0.9550   -1.0668 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3903    0.4149   -0.6688 C   0  0  1  0  0  0  0  0  0  0  0  0
   -6.5028    0.3570    0.1344 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.2738    1.1328    0.0623 C   0  0  1  0  0  0  0  0  0  0  0  0
   -4.7899    2.4550    0.6041 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.8130    2.1510    1.5149 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7818    0.3666    1.1630 N   0  0  0  0  0  0  0  0  0  0  0  0
    7.6753    0.1736    1.2519 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.0446    1.0961   -0.3103 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.4876    1.9446    1.1635 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.3591    1.2161    1.0148 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.7616    1.3907   -0.7974 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.9894   -1.2519    0.8194 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.3978   -0.5380   -1.8975 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.6130   -2.2911   -0.7312 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.4192   -0.9018   -1.7939 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.4288   -1.4741   -0.7459 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.0967   -1.5018    0.9012 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.2227    1.1792    0.6274 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.5334    0.8892   -0.9629 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.3460   -0.0502    1.7439 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.8963    1.4421    0.8888 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.6316   -1.4501   -0.0709 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.1657   -0.0229   -1.0903 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2384    0.7951    0.7458 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8011   -0.6286    1.7453 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8425   -2.0917   -0.2008 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2814   -0.5320   -0.9545 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2285   -1.5005    1.8131 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9367   -2.6601   -0.2872 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.2491   -2.0755    0.7765 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.7701   -1.5194   -1.5517 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0834   -0.8676   -1.8001 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.5851    0.9963   -1.5922 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.2929   -0.2241    0.9183 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4792    1.3849   -0.6871 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9573    2.9460    1.1272 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1754    3.1086   -0.1990 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3949    1.6564    2.2648 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0190    0.8744    1.6350 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  1  0
  3  5  1  0
  5  6  1  0
  6  7  1  0
  7  8  1  0
  8  9  1  0
  9 10  1  0
 10 11  1  0
 11 12  1  0
 12 13  1  0
 13 14  1  0
 14 15  1  0
 15 16  1  0
 15 17  1  0
 17 18  1  0
 18 19  1  0
 17 20  1  0
 20 12  1  0
  1 21  1  0
  1 22  1  0
  1 23  1  0
  2 24  1  0
  2 25  1  0
  3 26  1  1
  4 27  1  0
  5 28  1  0
  5 29  1  0
  6 30  1  0
  6 31  1  0
  7 32  1  0
  7 33  1  0
  8 34  1  0
  8 35  1  0
  9 36  1  0
  9 37  1  0
 10 38  1  0
 10 39  1  0
 11 40  1  0
 11 41  1  0
 12 42  1  1
 13 43  1  0
 13 44  1  0
 14 45  1  0
 14 46  1  0
 15 47  1  6
 16 48  1  0
 17 49  1  6
 18 50  1  0
 18 51  1  0
 19 52  1  0
 20 53  1  0
M  END


  Mrv1652309122214082D          

 20 20  0  0  1  0            999 V2000
    2.8579   -6.6000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -6.1875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868   -6.6000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868   -7.4250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013   -6.1875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158   -6.6000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4302   -6.1875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.1447   -6.6000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.8592   -6.1875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.5737   -6.6000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.2881   -6.1875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.0026   -6.6000    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   10.7171   -6.1875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   11.4315   -6.6000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   11.4315   -7.4250    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   12.1460   -7.8375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   10.7171   -7.8375    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   10.7171   -8.6625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.0026   -9.0750    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   10.0026   -7.4250    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  1  0  0  0  0
  3  5  1  0  0  0  0
  5  6  1  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  1  0  0  0  0
 10 11  1  0  0  0  0
 12 11  1  6  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  1  0  0  0
 15 17  1  0  0  0  0
 17 18  1  1  0  0  0
 18 19  1  0  0  0  0
 17 20  1  0  0  0  0
 12 20  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0328561

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CCC(O)CCCCCCC[C@@H]1CC[C@@H](O)[C@@H](CO)N1

> <INCHI_IDENTIFIER>
InChI=1S/C16H33NO3/c1-2-14(19)9-7-5-3-4-6-8-13-10-11-16(20)15(12-18)17-13/h13-20H,2-12H2,1H3/t13-,14?,15-,16-/m1/s1

> <INCHI_KEY>
SEUBYHFHBZVRCC-QGAIPKOMSA-N

> <FORMULA>
C16H33NO3

> <MOLECULAR_WEIGHT>
287.444

> <EXACT_MASS>
287.246043927

> <JCHEM_ACCEPTOR_COUNT>
4

> <JCHEM_ATOM_COUNT>
53

> <JCHEM_AVERAGE_POLARIZABILITY>
35.63228797548645

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
4

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
(2R,3R,6R)-6-(8-hydroxydecyl)-2-(hydroxymethyl)piperidin-3-ol

> <JCHEM_LOGP>
2.0611773236666657

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
1

> <JCHEM_PHYSIOLOGICAL_CHARGE>
1

> <JCHEM_PKA>
15.253769530244927

> <JCHEM_PKA_STRONGEST_ACIDIC>
14.410000093022685

> <JCHEM_PKA_STRONGEST_BASIC>
9.4881361820699

> <JCHEM_POLAR_SURFACE_AREA>
72.72

> <JCHEM_REFRACTIVITY>
81.5797

> <JCHEM_ROTATABLE_BOND_COUNT>
10

> <JCHEM_RULE_OF_FIVE>
1

> <JCHEM_TRADITIONAL_IUPAC>
prosopinine

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 12-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   12-SEP-22         0                                  
HETATM    1  C   UNK     0       5.335 -12.320   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       6.668 -11.550   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       8.002 -12.320   0.000  0.00  0.00           C+0
HETATM    4  O   UNK     0       8.002 -13.860   0.000  0.00  0.00           O+0
HETATM    5  C   UNK     0       9.336 -11.550   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0      10.669 -12.320   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0      12.003 -11.550   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0      13.337 -12.320   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0      14.670 -11.550   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0      16.004 -12.320   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0      17.338 -11.550   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0      18.672 -12.320   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0      20.005 -11.550   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0      21.339 -12.320   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0      21.339 -13.860   0.000  0.00  0.00           C+0
HETATM   16  O   UNK     0      22.673 -14.630   0.000  0.00  0.00           O+0
HETATM   17  C   UNK     0      20.005 -14.630   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0      20.005 -16.170   0.000  0.00  0.00           C+0
HETATM   19  O   UNK     0      18.672 -16.940   0.000  0.00  0.00           O+0
HETATM   20  N   UNK     0      18.672 -13.860   0.000  0.00  0.00           N+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4    5                                                  
CONECT    4    3                                                            
CONECT    5    3    6                                                       
CONECT    6    5    7                                                       
CONECT    7    6    8                                                       
CONECT    8    7    9                                                       
CONECT    9    8   10                                                       
CONECT   10    9   11                                                       
CONECT   11   10   12                                                       
CONECT   12   11   13   20                                                  
CONECT   13   12   14                                                       
CONECT   14   13   15                                                       
CONECT   15   14   16   17                                                  
CONECT   16   15                                                            
CONECT   17   15   18   20                                                  
CONECT   18   17   19                                                       
CONECT   19   18                                                            
CONECT   20   17   12                                                       
MASTER        0    0    0    0    0    0    0    0   20    0   40    0
END

View in JSmol

Synonyms

Value	Source
6R-(8-Hydroxydecyl)-2R-(hydroxymethyl)-piperidin-3R-ol	ChEBI

Chemical Formula

C₁₆H₃₃NO₃

Average Mass

287.4440 Da

Monoisotopic Mass

287.24604 Da

IUPAC Name

(2R,3R,6R)-6-(8-hydroxydecyl)-2-(hydroxymethyl)piperidin-3-ol

Traditional Name

prosopinine

CAS Registry Number

Not Available

SMILES

CCC(O)CCCCCCC[C@@H]1CC[C@@H](O)[C@@H](CO)N1

InChI Identifier

InChI=1S/C16H33NO3/c1-2-14(19)9-7-5-3-4-6-8-13-10-11-16(20)15(12-18)17-13/h13-20H,2-12H2,1H3/t13-,14?,15-,16-/m1/s1

InChI Key

SEUBYHFHBZVRCC-QGAIPKOMSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Prosopis africana	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as alkaloids and derivatives. These are naturally occurring chemical compounds that contain mostly basic nitrogen atoms. This group also includes some related compounds with neutral and even weakly acidic properties. Also some synthetic compounds of similar structure are attributed to alkaloids. In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen, sulfur and more rarely other elements such as chlorine, bromine, and phosphorus.

Kingdom

Organic compounds

Super Class

Alkaloids and derivatives

Class

Not Available

Sub Class

Not Available

Direct Parent

Alkaloids and derivatives

Alternative Parents

Substituents

Alkaloid or derivatives
Piperidine
1,2-aminoalcohol
Secondary alcohol
Secondary aliphatic amine
Secondary amine
Organoheterocyclic compound
Azacycle
Organopnictogen compound
Primary alcohol
Organic oxygen compound
Organooxygen compound
Organonitrogen compound
Organic nitrogen compound
Alcohol
Hydrocarbon derivative
Amine
Aliphatic heteromonocyclic compound

Molecular Framework

Aliphatic heteromonocyclic compounds

External Descriptors

piperidine alkaloid (CHEBI:73903 )
hydroxypiperidine (CHEBI:73903 )
Sphingoid base analogs (LMSP01080049 )

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	2.06	ChemAxon
pKa (Strongest Acidic)	14.41	ChemAxon
pKa (Strongest Basic)	9.49	ChemAxon
Physiological Charge	1	ChemAxon
Hydrogen Acceptor Count	4	ChemAxon
Hydrogen Donor Count	4	ChemAxon
Polar Surface Area	72.72 Å²	ChemAxon
Rotatable Bond Count	10	ChemAxon
Refractivity	81.58 m³·mol⁻¹	ChemAxon
Polarizability	35.63 Å³	ChemAxon
Number of Rings	1	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

C00002067

Chemspider ID

24823233

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

42608371

PDB ID

Not Available

ChEBI ID

73903

Good Scents ID

Not Available

References

General References

Gnamm C, Brodner K, Krauter CM, Helmchen G: A configurational switch based on iridium-catalyzed allylic cyclization: application in asymmetric total syntheses of prosopis, dendrobate, and spruce alkaloids. Chemistry. 2009 Oct 12;15(40):10514-32. doi: 10.1002/chem.200901316. [PubMed:19731272 ]
Cani I, Righini M, Cenni P, Foschi M: Teaching NeuroImage: Partially Reversible Widespread Leukoencephalopathy Associated With Atypical Hemolytic Uremic Syndrome. Neurology. 2022 Sep 21. pii: WNL.0000000000201378. doi: 10.1212/WNL.0000000000201378. [PubMed:36130844 ]
Sasaki R, Morimoto S, Ozawa F, Okano H, Yoshida M, Ishiura H, Tsuji S, Kuzuhara S, Kokubo Y: APOE Alleles With Tau and Abeta Pathology In Patients With Amyotrophic Lateral Sclerosis and Parkinsonism-Dementia Complex in the Kii Peninsula. Neurology. 2022 Sep 21. pii: WNL.0000000000201156. doi: 10.1212/WNL.0000000000201156. [PubMed:36130843 ]
Zhang Z, Wang M, Gill D, Liu X: Genetically Predicted Smoking and Alcohol Consumption and Functional Outcome After Ischemic Stroke. Neurology. 2022 Sep 21. pii: WNL.0000000000201291. doi: 10.1212/WNL.0000000000201291. [PubMed:36130842 ]
Khamis S, Mitakidou MR, Champion M, Goyal S, Jones RL, Siddiqui A, Sabanathan S, Hedderly T, Lin JP, Jungbluth H, Papandreou A: Clinical Reasoning: A Teenage Girl With Progressive Hyperkinetic Movements, Seizures, and Encephalopathy. Neurology. 2022 Sep 21. pii: WNL.0000000000201385. doi: 10.1212/WNL.0000000000201385. [PubMed:36130841 ]
Rosenberg A, Ohlund-Wistbacka U, Hall A, Bonnard A, Hagman G, Ryden M, Thunborg C, Wiggenraad F, Sandebring-Matton A, Solomon A, Kivipelto M: beta-Amyloid, Tau, Neurodegeneration Classification and Eligibility for Anti-amyloid Treatment in a Memory Clinic Population. Neurology. 2022 Sep 21. pii: WNL.0000000000201043. doi: 10.1212/WNL.0000000000201043. [PubMed:36130840 ]
Lai NJ, Ngu EL, Pang JR, Wong KH, Ardianto C, Ming LC, Lim SH, Walvekar SG, Anwar A, Yow YY: Carrageenophyte Kappaphycus malesianus Inhibits Microglia-Mediated Neuroinflammation via Suppression of AKT/NF-kappaB and ERK Signaling Pathways. Mar Drugs. 2022 Aug 20;20(8). pii: md20080534. doi: 10.3390/md20080534. [PubMed:36005538 ]
Silverman A, Beres S: Child Neurology: Horner Syndrome in an Otherwise Well-Appearing Infant. Neurology. 2022 Sep 21. pii: WNL.0000000000201377. doi: 10.1212/WNL.0000000000201377. [PubMed:36130839 ]
Harada Y, Wang SH, Juel VC: Clinical Reasoning: A 36-Year-Old Man With Asymmetric Muscle Weakness. Neurology. 2022 Sep 21. pii: WNL.0000000000201379. doi: 10.1212/WNL.0000000000201379. [PubMed:36130838 ]
Guest O, Memon AA, Chukweubuka A, Zaheer M, Siddiqi N: Robotic low anterior resection for locally advanced rectal cancer - A video vignette. Colorectal Dis. 2022 Sep 21. doi: 10.1111/codi.16345. [PubMed:36130837 ]
LOTUS database [Link]

Showing NP-Card for prosopinine (NP0328561)

MOL for NP0328561 (prosopinine)

3D MOL for NP0328561 (prosopinine)

3D SDF for NP0328561 (prosopinine)

3D-SDF for NP0328561 (prosopinine)

PDB for NP0328561 (prosopinine)

3D PDB for NP0328561 (prosopinine)

SMILES for NP0328561 (prosopinine)

INCHI for NP0328561 (prosopinine)

Structure for NP0328561 (prosopinine)

3D Structure for NP0328561 (prosopinine)