NP-MRD: Showing NP-Card for diosmine (NP0327320)

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Record Information

Version

2.0

Created at

2022-09-12 09:47:55 UTC

Updated at

2022-09-12 09:47:55 UTC

NP-MRD ID

NP0327320

Secondary Accession Numbers

None

Natural Product Identification

Common Name

diosmine

Description

Diosmin, also known as barosmin or daflon, belongs to the class of organic compounds known as flavonoid-7-o-glycosides. These are phenolic compounds containing a flavonoid moiety which is O-glycosidically linked to carbohydrate moiety at the C7-position. This leads to a reduction in the release of inflammatory mediators, principally oxygen free radicals and prostaglandins (PGE2, PGF2a). Diosmin is an extremely weak basic (essentially neutral) compound (based on its pKa). Outside of the human body, Diosmin is found, on average, in the highest concentration within a few different foods, such as hyssops, peppermints, and lemons. Diosmin has also been detected, but not quantified in, several different foods, such as green vegetables, mandarin orange (clementine, tangerine), rosemaries, spearmints, and sweet oranges. This could make diosmin a potential biomarker for the consumption of these foods. The enhanced version of diosmin, Vasculera, is sold as a medical food product. Furthermore, diosmin with hesperidine decreases the diameter of lymphatic capillaries and the intralymphatic pressure. It is also speculated that diosmin might have potential in the treatment of neurodegenerative diseases, such as Alzheimer's disease, and its anti-inflammatory and anti-apoptotic activity has been demonstrated in neuronal cells, in vitro. It is an oral phlebotropic drug used in the treatment of venous disease, i.E., Chronic venous insufficiency (CVI) including spider and varicose veins, leg swelling (edema), stasis dermatitis and venous ulcers. diosmine is found in Abies nephrolepis, Citrus limon, Helichrysum arenarium, Hyssopus officinalis, Linaria macroura, Lomelosia caucasica, Meehania urticifolia, Mentha piperita, Mentha spicata, Scutellaria baicalensis and Sechium edule. diosmine was first documented in 2011 (PMID: 21477647). ,However, diosmin products have been used in Europe for over 40 years with no safety issues.

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv0541 02241218112D          

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M  END

     RDKit          3D

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M  END


  Mrv0541 02241218112D          

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   -1.7322    1.7322    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3196    2.4747    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7322    3.2173    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3196    1.0722    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4946    1.0722    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0829    0.3296    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7422    0.3296    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.5672    0.3296    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9797    1.0722    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5672    1.7322    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.9797   -0.4121    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.8047   -0.4121    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2173   -1.0722    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7422    1.7322    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0829    1.7322    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4946    2.4747    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0829    3.2173    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.2173    1.7322    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.8047    1.0722    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2173    0.3296    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0423    0.3296    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  2  0  0  0  0
  2  7  1  0  0  0  0
  3  4  1  0  0  0  0
  4  5  2  0  0  0  0
  4 22  1  0  0  0  0
  5  6  1  0  0  0  0
  6  7  2  0  0  0  0
  6 11  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  8 12  2  0  0  0  0
  9 10  2  0  0  0  0
 10 11  1  0  0  0  0
 10 16  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 14 19  2  0  0  0  0
 15 16  2  0  0  0  0
 16 17  1  0  0  0  0
 17 18  2  0  0  0  0
 18 19  1  0  0  0  0
 19 20  1  0  0  0  0
 20 21  1  0  0  0  0
 22 23  1  0  0  0  0
 23 24  1  0  0  0  0
 23 26  1  0  0  0  0
 24 25  1  0  0  0  0
 24 38  1  0  0  0  0
 26 27  1  0  0  0  0
 27 28  1  0  0  0  0
 27 37  1  0  0  0  0
 28 29  1  0  0  0  0
 29 30  1  0  0  0  0
 30 31  1  0  0  0  0
 30 33  1  0  0  0  0
 31 32  1  0  0  0  0
 31 41  1  0  0  0  0
 33 34  1  0  0  0  0
 34 35  1  0  0  0  0
 34 42  1  0  0  0  0
 36 37  1  0  0  0  0
 37 38  1  0  0  0  0
 38 39  1  0  0  0  0
 40 41  1  0  0  0  0
 41 42  1  0  0  0  0
 42 43  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0327320

> <DATABASE_NAME>
NP-MRD

> <SMILES>
COC1=C(O)C=C(C=C1)C1=CC(=O)C2=C(O1)C=C(OC1OC(COC3OC(C)C(O)C(O)C3O)C(O)C(O)C1O)C=C2O

> <INCHI_IDENTIFIER>
InChI=1S/C28H32O15/c1-10-21(32)23(34)25(36)27(40-10)39-9-19-22(33)24(35)26(37)28(43-19)41-12-6-14(30)20-15(31)8-17(42-18(20)7-12)11-3-4-16(38-2)13(29)5-11/h3-8,10,19,21-30,32-37H,9H2,1-2H3

> <INCHI_KEY>
GZSOSUNBTXMUFQ-UHFFFAOYSA-N

> <FORMULA>
C28H32O15

> <MOLECULAR_WEIGHT>
608.5447

> <EXACT_MASS>
608.174120354

> <JCHEM_ACCEPTOR_COUNT>
15

> <JCHEM_AVERAGE_POLARIZABILITY>
59.89642289505568

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
8

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-[(3,4,5-trihydroxy-6-{[(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy]methyl}oxan-2-yl)oxy]-4H-chromen-4-one

> <ALOGPS_LOGP>
0.08

> <JCHEM_LOGP>
-0.44297590433333345

> <ALOGPS_LOGS>
-2.60

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
5

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
9.584533864342719

> <JCHEM_PKA_STRONGEST_ACIDIC>
8.475596774388157

> <JCHEM_PKA_STRONGEST_BASIC>
-3.6121823516836606

> <JCHEM_POLAR_SURFACE_AREA>
234.28999999999996

> <JCHEM_REFRACTIVITY>
142.39110000000005

> <JCHEM_ROTATABLE_BOND_COUNT>
7

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
1.54e+00 g/l

> <JCHEM_TRADITIONAL_IUPAC>
diosmine

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 24-FEB-12   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   24-FEB-12         0                                  
HETATM    1  O   UNK     0      -7.546  -1.231   0.000  0.00  0.00           O+0
HETATM    2  C   UNK     0      -6.160  -0.615   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      -6.160   0.923   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      -4.774   1.693   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      -3.541   0.923   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0      -3.541  -0.615   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0      -4.774  -1.385   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0      -4.774  -2.925   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0      -3.541  -3.695   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0      -2.155  -2.925   0.000  0.00  0.00           C+0
HETATM   11  O   UNK     0      -2.155  -1.385   0.000  0.00  0.00           O+0
HETATM   12  O   UNK     0      -6.160  -3.695   0.000  0.00  0.00           O+0
HETATM   13  O   UNK     0       3.233  -2.771   0.000  0.00  0.00           O+0
HETATM   14  C   UNK     0       1.847  -3.695   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       0.461  -2.925   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0      -0.769  -3.695   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0      -0.769  -5.235   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       0.461  -6.006   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       1.847  -5.235   0.000  0.00  0.00           C+0
HETATM   20  O   UNK     0       3.233  -6.006   0.000  0.00  0.00           O+0
HETATM   21  C   UNK     0       4.619  -5.235   0.000  0.00  0.00           C+0
HETATM   22  O   UNK     0      -4.774   3.233   0.000  0.00  0.00           O+0
HETATM   23  C   UNK     0      -3.233   3.233   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0      -2.463   4.619   0.000  0.00  0.00           C+0
HETATM   25  O   UNK     0      -3.233   6.006   0.000  0.00  0.00           O+0
HETATM   26  O   UNK     0      -2.463   2.001   0.000  0.00  0.00           O+0
HETATM   27  C   UNK     0      -0.923   2.001   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0      -0.155   0.615   0.000  0.00  0.00           C+0
HETATM   29  O   UNK     0       1.385   0.615   0.000  0.00  0.00           O+0
HETATM   30  C   UNK     0       2.925   0.615   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0       3.695   2.001   0.000  0.00  0.00           C+0
HETATM   32  O   UNK     0       2.925   3.233   0.000  0.00  0.00           O+0
HETATM   33  O   UNK     0       3.695  -0.769   0.000  0.00  0.00           O+0
HETATM   34  C   UNK     0       5.235  -0.769   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0       6.006  -2.001   0.000  0.00  0.00           C+0
HETATM   36  O   UNK     0       1.385   3.233   0.000  0.00  0.00           O+0
HETATM   37  C   UNK     0      -0.155   3.233   0.000  0.00  0.00           C+0
HETATM   38  C   UNK     0      -0.923   4.619   0.000  0.00  0.00           C+0
HETATM   39  O   UNK     0      -0.155   6.006   0.000  0.00  0.00           O+0
HETATM   40  O   UNK     0       6.006   3.233   0.000  0.00  0.00           O+0
HETATM   41  C   UNK     0       5.235   2.001   0.000  0.00  0.00           C+0
HETATM   42  C   UNK     0       6.006   0.615   0.000  0.00  0.00           C+0
HETATM   43  O   UNK     0       7.546   0.615   0.000  0.00  0.00           O+0
CONECT    1    2                                                            
CONECT    2    1    3    7                                                  
CONECT    3    2    4                                                       
CONECT    4    3    5   22                                                  
CONECT    5    4    6                                                       
CONECT    6    5    7   11                                                  
CONECT    7    2    6    8                                                  
CONECT    8    7    9   12                                                  
CONECT    9    8   10                                                       
CONECT   10    9   11   16                                                  
CONECT   11    6   10                                                       
CONECT   12    8                                                            
CONECT   13   14                                                            
CONECT   14   13   15   19                                                  
CONECT   15   14   16                                                       
CONECT   16   10   15   17                                                  
CONECT   17   16   18                                                       
CONECT   18   17   19                                                       
CONECT   19   14   18   20                                                  
CONECT   20   19   21                                                       
CONECT   21   20                                                            
CONECT   22    4   23                                                       
CONECT   23   22   24   26                                                  
CONECT   24   23   25   38                                                  
CONECT   25   24                                                            
CONECT   26   23   27                                                       
CONECT   27   26   28   37                                                  
CONECT   28   27   29                                                       
CONECT   29   28   30                                                       
CONECT   30   29   31   33                                                  
CONECT   31   30   32   41                                                  
CONECT   32   31                                                            
CONECT   33   30   34                                                       
CONECT   34   33   35   42                                                  
CONECT   35   34                                                            
CONECT   36   37                                                            
CONECT   37   27   36   38                                                  
CONECT   38   24   37   39                                                  
CONECT   39   38                                                            
CONECT   40   41                                                            
CONECT   41   31   40   42                                                  
CONECT   42   34   41   43                                                  
CONECT   43   42                                                            
MASTER        0    0    0    0    0    0    0    0   43    0   94    0
END

View in JSmol

Synonyms

Value	Source
5,7,3'-Trihydroxy-4'-methoxyflavone 7-O-rutinoside	HMDB
Barosmin	HMDB
Daflon	HMDB
Diosmetin 7-O-rutinoside	HMDB
Diosmetin 7-rutinoside	HMDB
Diosmetin-7-O-rutinoside	HMDB
Diosmil	HMDB
Diosmin, ban, inn	HMDB
Diosmine	HMDB
Diosminum	HMDB
Diovenor	HMDB
Flebosten	HMDB
Luteolin 4'-methyl ether 7-rutinoside	HMDB
Rioven	HMDB
Salinigricoflavonoloside	HMDB
Tovene	HMDB
Ven-detrex	HMDB
Veno-V	HMDB
Venosmine	HMDB

Chemical Formula

C₂₈H₃₂O₁₅

Average Mass

608.5447 Da

Monoisotopic Mass

608.17412 Da

IUPAC Name

5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-[(3,4,5-trihydroxy-6-{[(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy]methyl}oxan-2-yl)oxy]-4H-chromen-4-one

Traditional Name

diosmine

CAS Registry Number

Not Available

SMILES

COC1=C(O)C=C(C=C1)C1=CC(=O)C2=C(O1)C=C(OC1OC(COC3OC(C)C(O)C(O)C3O)C(O)C(O)C1O)C=C2O

InChI Identifier

InChI=1S/C28H32O15/c1-10-21(32)23(34)25(36)27(40-10)39-9-19-22(33)24(35)26(37)28(43-19)41-12-6-14(30)20-15(31)8-17(42-18(20)7-12)11-3-4-16(38-2)13(29)5-11/h3-8,10,19,21-30,32-37H,9H2,1-2H3

InChI Key

GZSOSUNBTXMUFQ-UHFFFAOYSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Abies nephrolepis	LOTUS Database	35616633
Citrus limon	LOTUS Database	35616633
Helichrysum arenarium	LOTUS Database	35616633
Hyssopus officinalis L.	LOTUS Database	35616633
Linaria macroura	LOTUS Database	35616633
Lomelosia caucasica	LOTUS Database	35616633
Meehania urticifolia	LOTUS Database	35616633
Mentha piperita	LOTUS Database	35616633
Mentha spicata	LOTUS Database	35616633
Scutellaria baicalensis	LOTUS Database	35616633
Sechium edule	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as flavonoid-7-o-glycosides. These are phenolic compounds containing a flavonoid moiety which is O-glycosidically linked to carbohydrate moiety at the C7-position.

Kingdom

Organic compounds

Super Class

Phenylpropanoids and polyketides

Class

Flavonoids

Sub Class

Flavonoid glycosides

Direct Parent

Flavonoid-7-O-glycosides

Alternative Parents

Substituents

Flavonoid-7-o-glycoside
4p-methoxyflavonoid-skeleton
3'-hydroxyflavonoid
5-hydroxyflavonoid
Flavone
Hydroxyflavonoid
Phenolic glycoside
Chromone
Disaccharide
Glycosyl compound
O-glycosyl compound
Benzopyran
Methoxyphenol
1-benzopyran
Phenoxy compound
Anisole
Methoxybenzene
Phenol ether
Phenol
Pyranone
1-hydroxy-2-unsubstituted benzenoid
Alkyl aryl ether
1-hydroxy-4-unsubstituted benzenoid
Benzenoid
Oxane
Pyran
Monocyclic benzene moiety
Vinylogous acid
Heteroaromatic compound
Secondary alcohol
Polyol
Acetal
Organoheterocyclic compound
Oxacycle
Ether
Organooxygen compound
Alcohol
Hydrocarbon derivative
Organic oxygen compound
Organic oxide
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	0.08	ALOGPS
logP	-0.44	ChemAxon
logS	-2.6	ALOGPS
pKa (Strongest Acidic)	8.48	ChemAxon
pKa (Strongest Basic)	-3.6	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	15	ChemAxon
Hydrogen Donor Count	8	ChemAxon
Polar Surface Area	234.29 Å²	ChemAxon
Rotatable Bond Count	7	ChemAxon
Refractivity	142.39 m³·mol⁻¹	ChemAxon
Polarizability	59.9 Å³	ChemAxon
Number of Rings	5	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	Yes	ChemAxon

External Links

HMDB ID

HMDB0029548

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

KNApSAcK ID

Chemspider ID

KEGG Compound ID

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Diosmin

METLIN ID

Not Available

PubChem Compound

5353588

PDB ID

Not Available

ChEBI ID

1188022

Good Scents ID

Not Available

References

General References

Dholakiya SL, Benzeroual KE: Protective effect of diosmin on LPS-induced apoptosis in PC12 cells and inhibition of TNF-alpha expression. Toxicol In Vitro. 2011 Aug;25(5):1039-44. doi: 10.1016/j.tiv.2011.04.003. Epub 2011 Apr 6. [PubMed:21477647 ]
LOTUS database [Link]

Showing NP-Card for diosmine (NP0327320)

MOL for NP0327320 (diosmine)

3D MOL for NP0327320 (diosmine)

3D SDF for NP0327320 (diosmine)

3D-SDF for NP0327320 (diosmine)

PDB for NP0327320 (diosmine)

3D PDB for NP0327320 (diosmine)

SMILES for NP0327320 (diosmine)

INCHI for NP0327320 (diosmine)

Structure for NP0327320 (diosmine)

3D Structure for NP0327320 (diosmine)