NP-MRD: Showing NP-Card for 3,5,6-trihydroxy-2-(4-hydroxyphenyl)-7-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}chromen-4-one (NP0324486)

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Record Information

Version

2.0

Created at

2022-09-12 04:35:37 UTC

Updated at

2022-09-12 04:35:37 UTC

NP-MRD ID

NP0324486

Secondary Accession Numbers

None

Natural Product Identification

Common Name

3,5,6-trihydroxy-2-(4-hydroxyphenyl)-7-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}chromen-4-one

Description

6-Hydroxykaempferol 7-glucoside belongs to the class of organic compounds known as flavonoid-7-o-glycosides. These are phenolic compounds containing a flavonoid moiety which is O-glycosidically linked to carbohydrate moiety at the C7-position. 3,5,6-trihydroxy-2-(4-hydroxyphenyl)-7-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}chromen-4-one is found in Buphthalmum salicifolium, Neurolaena lobata and Tagetes lucida. 6-Hydroxykaempferol 7-glucoside is an extremely weak basic (essentially neutral) compound (based on its pKa).

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv0541 02241208442D          

 33 36  0  0  0  0            999 V2000
   -2.5012    2.0625    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7862    1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0712    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3576    1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3574    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3574    2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0712    2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.7861    2.0625    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.0710    1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0710    0.8251    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3574    0.4125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3576    0.8251    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0712    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7862    0.8251    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5012    0.4125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5012   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2148   -0.8250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2148   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9298   -2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9298   -2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.7861    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7861   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5011   -0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2147   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2147    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5011    0.8251    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0712   -0.4125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7862   -0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7862   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5012   -2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5012   -2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.9298   -0.8250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0712   -2.0625    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  2  0  0  0  0
  2 14  1  0  0  0  0
  3  4  1  0  0  0  0
  3  7  1  0  0  0  0
  4  5  1  0  0  0  0
  4 12  2  0  0  0  0
  5  6  2  0  0  0  0
  5  9  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  2  0  0  0  0
 10 11  1  0  0  0  0
 10 21  1  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  0  0  0  0
 13 14  2  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 16 28  1  0  0  0  0
 17 18  1  0  0  0  0
 18 19  1  0  0  0  0
 18 30  1  0  0  0  0
 19 20  1  0  0  0  0
 21 22  1  0  0  0  0
 21 26  2  0  0  0  0
 22 23  2  0  0  0  0
 23 24  1  0  0  0  0
 24 25  2  0  0  0  0
 24 32  1  0  0  0  0
 25 26  1  0  0  0  0
 27 28  1  0  0  0  0
 28 29  1  0  0  0  0
 29 30  1  0  0  0  0
 29 33  1  0  0  0  0
 30 31  1  0  0  0  0
M  END

     RDKit          3D

 53 56  0  0  0  0  0  0  0  0999 V2000
    3.5184    3.4833   -0.3994 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.2023    2.2737   -0.2746 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.1690    1.2751   -0.2440 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.4982    1.6318   -0.3537 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.7899   -0.0304   -0.1070 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7088   -1.1706   -0.0611 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.1589   -2.4462    0.0841 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.9478   -3.5727    0.1364 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.3207   -3.5043    0.0487 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.0974   -4.6546    0.1038 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.8700   -2.2572   -0.0940 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0629   -1.1076   -0.1473 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5015   -0.2666   -0.0102 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.5550    0.6291   -0.0330 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.2397    0.2899    0.0744 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7845    1.2457    0.0509 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0657    0.8268    0.1633 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2926    1.3922    0.1862 C   0  0  1  0  0  0  0  0  0  0  0  0
   -4.0532    0.8910   -0.8682 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3940   -0.4179   -0.7643 C   0  0  2  0  0  0  0  0  0  0  0  0
   -5.9121   -0.5182   -0.9550 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.3254   -1.8516   -0.8579 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9287   -1.1455    0.4350 C   0  0  1  0  0  0  0  0  0  0  0  0
   -2.6740   -1.7362    0.1605 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9183   -0.3790    1.7051 C   0  0  2  0  0  0  0  0  0  0  0  0
   -4.8431   -0.8000    2.6413 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0517    1.1168    1.5075 C   0  0  1  0  0  0  0  0  0  0  0  0
   -3.4496    1.8200    2.5339 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4437    2.5671   -0.0851 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3842    3.5492   -0.1158 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.8968    2.9571   -0.1985 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3035    4.2583   -0.3367 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.8700    1.9607   -0.1685 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7797    2.5860   -0.4541 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.0837   -2.5380    0.1562 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.5136   -4.5567    0.2490 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.4306   -4.9916    1.0121 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.9452   -2.1353   -0.1688 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.5490   -0.1641   -0.2595 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0351   -0.7401    0.1810 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3050    2.4755    0.0929 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9701   -0.9493   -1.6683 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.4588    0.0772   -0.2236 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1980   -0.1841   -1.9738 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.2492   -1.9540   -0.5775 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6159   -2.0304    0.5851 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7359   -2.3829   -0.5632 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9046   -0.5295    2.1808 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.2836   -1.6277    2.3176 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.0971    1.3767    1.3384 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0740    2.4226    3.0048 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2350    4.5216   -0.2100 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.6708    5.0148   -0.3657 H   0  0  0  0  0  0  0  0  0  0  0  0
 22 21  1  0
 21 20  1  0
 20 19  1  0
 19 18  1  0
 18 17  1  0
 17 16  1  0
 16 15  2  0
 15 14  1  0
 14 33  2  0
 33 31  1  0
 31 32  1  0
 31 29  2  0
 29 30  1  0
 33  2  1  0
  2  1  2  0
  2  3  1  0
  3  4  1  0
  3  5  2  0
  5 13  1  0
  5  6  1  0
  6  7  2  0
  7  8  1  0
  8  9  2  0
  9 10  1  0
  9 11  1  0
 11 12  2  0
 18 27  1  0
 27 28  1  0
 27 25  1  0
 25 26  1  0
 25 23  1  0
 23 24  1  0
 23 20  1  0
 29 16  1  0
 12  6  1  0
 13 14  1  0
 22 45  1  0
 21 43  1  0
 21 44  1  0
 20 42  1  6
 18 41  1  6
 15 40  1  0
 32 53  1  0
 30 52  1  0
  4 34  1  0
  7 35  1  0
  8 36  1  0
 10 37  1  0
 11 38  1  0
 12 39  1  0
 27 50  1  6
 28 51  1  0
 25 48  1  1
 26 49  1  0
 23 46  1  1
 24 47  1  0
M  END


  Mrv0541 02241208442D          

 33 36  0  0  0  0            999 V2000
   -2.5012    2.0625    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7862    1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0712    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3576    1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3574    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3574    2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0712    2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.7861    2.0625    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.0710    1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0710    0.8251    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3574    0.4125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3576    0.8251    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0712    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7862    0.8251    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5012    0.4125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5012   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2148   -0.8250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2148   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9298   -2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9298   -2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.7861    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7861   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5011   -0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2147   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2147    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5011    0.8251    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0712   -0.4125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7862   -0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7862   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5012   -2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5012   -2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.9298   -0.8250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0712   -2.0625    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  2  0  0  0  0
  2 14  1  0  0  0  0
  3  4  1  0  0  0  0
  3  7  1  0  0  0  0
  4  5  1  0  0  0  0
  4 12  2  0  0  0  0
  5  6  2  0  0  0  0
  5  9  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  2  0  0  0  0
 10 11  1  0  0  0  0
 10 21  1  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  0  0  0  0
 13 14  2  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 16 28  1  0  0  0  0
 17 18  1  0  0  0  0
 18 19  1  0  0  0  0
 18 30  1  0  0  0  0
 19 20  1  0  0  0  0
 21 22  1  0  0  0  0
 21 26  2  0  0  0  0
 22 23  2  0  0  0  0
 23 24  1  0  0  0  0
 24 25  2  0  0  0  0
 24 32  1  0  0  0  0
 25 26  1  0  0  0  0
 27 28  1  0  0  0  0
 28 29  1  0  0  0  0
 29 30  1  0  0  0  0
 29 33  1  0  0  0  0
 30 31  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0324486

> <DATABASE_NAME>
NP-MRD

> <SMILES>
OCC1OC(OC2=CC3=C(C(O)=C2O)C(=O)C(O)=C(O3)C2=CC=C(O)C=C2)C(O)C(O)C1O

> <INCHI_IDENTIFIER>
InChI=1S/C21H20O12/c22-6-11-14(25)17(28)19(30)21(33-11)32-10-5-9-12(15(26)13(10)24)16(27)18(29)20(31-9)7-1-3-8(23)4-2-7/h1-5,11,14,17,19,21-26,28-30H,6H2

> <INCHI_KEY>
IYEWEDZIDUAUTD-UHFFFAOYSA-N

> <FORMULA>
C21H20O12

> <MOLECULAR_WEIGHT>
464.3763

> <EXACT_MASS>
464.095476104

> <JCHEM_ACCEPTOR_COUNT>
12

> <JCHEM_AVERAGE_POLARIZABILITY>
43.96383118954054

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
8

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
3,5,6-trihydroxy-2-(4-hydroxyphenyl)-7-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4H-chromen-4-one

> <ALOGPS_LOGP>
0.50

> <JCHEM_LOGP>
-0.11176862933333384

> <ALOGPS_LOGS>
-2.33

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
4

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
8.856978595000946

> <JCHEM_PKA_STRONGEST_ACIDIC>
8.06238331759832

> <JCHEM_PKA_STRONGEST_BASIC>
-2.9810923549784256

> <JCHEM_POLAR_SURFACE_AREA>
206.6

> <JCHEM_REFRACTIVITY>
109.0066

> <JCHEM_ROTATABLE_BOND_COUNT>
4

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
2.16e+00 g/l

> <JCHEM_TRADITIONAL_IUPAC>
3,5,6-trihydroxy-2-(4-hydroxyphenyl)-7-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}chromen-4-one

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 24-FEB-12   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   24-FEB-12         0                                  
HETATM    1  O   UNK     0      -4.669   3.850   0.000  0.00  0.00           O+0
HETATM    2  C   UNK     0      -3.334   3.080   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      -2.000   3.850   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      -0.668   3.080   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       0.667   3.850   0.000  0.00  0.00           C+0
HETATM    6  O   UNK     0       0.667   5.390   0.000  0.00  0.00           O+0
HETATM    7  O   UNK     0      -2.000   5.390   0.000  0.00  0.00           O+0
HETATM    8  O   UNK     0       3.334   3.850   0.000  0.00  0.00           O+0
HETATM    9  C   UNK     0       1.999   3.080   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       1.999   1.540   0.000  0.00  0.00           C+0
HETATM   11  O   UNK     0       0.667   0.770   0.000  0.00  0.00           O+0
HETATM   12  C   UNK     0      -0.668   1.540   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0      -2.000   0.770   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0      -3.334   1.540   0.000  0.00  0.00           C+0
HETATM   15  O   UNK     0      -4.669   0.770   0.000  0.00  0.00           O+0
HETATM   16  C   UNK     0      -4.669  -0.770   0.000  0.00  0.00           C+0
HETATM   17  O   UNK     0      -6.001  -1.540   0.000  0.00  0.00           O+0
HETATM   18  C   UNK     0      -6.001  -3.080   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0      -7.336  -3.850   0.000  0.00  0.00           C+0
HETATM   20  O   UNK     0      -7.336  -5.390   0.000  0.00  0.00           O+0
HETATM   21  C   UNK     0       3.334   0.770   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0       3.334  -0.770   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0       4.669  -1.540   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0       6.001  -0.770   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0       6.001   0.770   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0       4.669   1.540   0.000  0.00  0.00           C+0
HETATM   27  O   UNK     0      -2.000  -0.770   0.000  0.00  0.00           O+0
HETATM   28  C   UNK     0      -3.334  -1.540   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0      -3.334  -3.080   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0      -4.669  -3.850   0.000  0.00  0.00           C+0
HETATM   31  O   UNK     0      -4.669  -5.390   0.000  0.00  0.00           O+0
HETATM   32  O   UNK     0       7.336  -1.540   0.000  0.00  0.00           O+0
HETATM   33  O   UNK     0      -2.000  -3.850   0.000  0.00  0.00           O+0
CONECT    1    2                                                            
CONECT    2    1    3   14                                                  
CONECT    3    2    4    7                                                  
CONECT    4    3    5   12                                                  
CONECT    5    4    6    9                                                  
CONECT    6    5                                                            
CONECT    7    3                                                            
CONECT    8    9                                                            
CONECT    9    5    8   10                                                  
CONECT   10    9   11   21                                                  
CONECT   11   10   12                                                       
CONECT   12    4   11   13                                                  
CONECT   13   12   14                                                       
CONECT   14    2   13   15                                                  
CONECT   15   14   16                                                       
CONECT   16   15   17   28                                                  
CONECT   17   16   18                                                       
CONECT   18   17   19   30                                                  
CONECT   19   18   20                                                       
CONECT   20   19                                                            
CONECT   21   10   22   26                                                  
CONECT   22   21   23                                                       
CONECT   23   22   24                                                       
CONECT   24   23   25   32                                                  
CONECT   25   24   26                                                       
CONECT   26   21   25                                                       
CONECT   27   28                                                            
CONECT   28   16   27   29                                                  
CONECT   29   28   30   33                                                  
CONECT   30   18   29   31                                                  
CONECT   31   30                                                            
CONECT   32   24                                                            
CONECT   33   29                                                            
MASTER        0    0    0    0    0    0    0    0   33    0   72    0
END

View in JSmol

Synonyms

Value	Source
6-Hydroxykaempferol 7-alloside	HMDB
7-(beta-D-Allopyranosyloxy)-3,5,6-trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one	HMDB

Chemical Formula

C₂₁H₂₀O₁₂

Average Mass

464.3763 Da

Monoisotopic Mass

464.09548 Da

IUPAC Name

3,5,6-trihydroxy-2-(4-hydroxyphenyl)-7-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4H-chromen-4-one

Traditional Name

3,5,6-trihydroxy-2-(4-hydroxyphenyl)-7-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}chromen-4-one

CAS Registry Number

Not Available

SMILES

OCC1OC(OC2=CC3=C(C(O)=C2O)C(=O)C(O)=C(O3)C2=CC=C(O)C=C2)C(O)C(O)C1O

InChI Identifier

InChI=1S/C21H20O12/c22-6-11-14(25)17(28)19(30)21(33-11)32-10-5-9-12(15(26)13(10)24)16(27)18(29)20(31-9)7-1-3-8(23)4-2-7/h1-5,11,14,17,19,21-26,28-30H,6H2

InChI Key

IYEWEDZIDUAUTD-UHFFFAOYSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Buphthalmum salicifolium	LOTUS Database	35616633
Neurolaena lobata	LOTUS Database	35616633
Tagetes lucida	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as flavonoid-7-o-glycosides. These are phenolic compounds containing a flavonoid moiety which is O-glycosidically linked to carbohydrate moiety at the C7-position.

Kingdom

Organic compounds

Super Class

Phenylpropanoids and polyketides

Class

Flavonoids

Sub Class

Flavonoid glycosides

Direct Parent

Flavonoid-7-O-glycosides

Alternative Parents

Substituents

Flavonoid-7-o-glycoside
3-hydroxyflavone
3-hydroxyflavonoid
4'-hydroxyflavonoid
5-hydroxyflavonoid
6-hydroxyflavonoid
Flavone
Hydroxyflavonoid
Phenolic glycoside
Hexose monosaccharide
Chromone
Glycosyl compound
O-glycosyl compound
Benzopyran
1-benzopyran
1-hydroxy-4-unsubstituted benzenoid
1-hydroxy-2-unsubstituted benzenoid
Phenol
Pyranone
Oxane
Monocyclic benzene moiety
Pyran
Monosaccharide
Benzenoid
Heteroaromatic compound
Vinylogous acid
Secondary alcohol
Organoheterocyclic compound
Oxacycle
Acetal
Polyol
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Alcohol
Organic oxygen compound
Primary alcohol
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	0.5	ALOGPS
logP	-0.11	ChemAxon
logS	-2.3	ALOGPS
pKa (Strongest Acidic)	8.06	ChemAxon
pKa (Strongest Basic)	-3	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	12	ChemAxon
Hydrogen Donor Count	8	ChemAxon
Polar Surface Area	206.6 Å²	ChemAxon
Rotatable Bond Count	4	ChemAxon
Refractivity	109.01 m³·mol⁻¹	ChemAxon
Polarizability	43.96 Å³	ChemAxon
Number of Rings	4	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

HMDB0034725

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

FDB013262

KNApSAcK ID

C00005307

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

14825511

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for 3,5,6-trihydroxy-2-(4-hydroxyphenyl)-7-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}chromen-4-one (NP0324486)

MOL for NP0324486 (3,5,6-trihydroxy-2-(4-hydroxyphenyl)-7-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}chromen-4-one)

3D MOL for NP0324486 (3,5,6-trihydroxy-2-(4-hydroxyphenyl)-7-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}chromen-4-one)

3D SDF for NP0324486 (3,5,6-trihydroxy-2-(4-hydroxyphenyl)-7-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}chromen-4-one)

3D-SDF for NP0324486 (3,5,6-trihydroxy-2-(4-hydroxyphenyl)-7-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}chromen-4-one)

PDB for NP0324486 (3,5,6-trihydroxy-2-(4-hydroxyphenyl)-7-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}chromen-4-one)

3D PDB for NP0324486 (3,5,6-trihydroxy-2-(4-hydroxyphenyl)-7-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}chromen-4-one)

SMILES for NP0324486 (3,5,6-trihydroxy-2-(4-hydroxyphenyl)-7-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}chromen-4-one)

INCHI for NP0324486 (3,5,6-trihydroxy-2-(4-hydroxyphenyl)-7-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}chromen-4-one)

Structure for NP0324486 (3,5,6-trihydroxy-2-(4-hydroxyphenyl)-7-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}chromen-4-one)

3D Structure for NP0324486 (3,5,6-trihydroxy-2-(4-hydroxyphenyl)-7-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}chromen-4-one)