NP-MRD: Showing NP-Card for methyl (2r)-2-(acetyloxy)-2-[(1r,2s,5r,6r,13s,14r,16s)-14-(acetyloxy)-6-(furan-3-yl)-1,5,15,15-tetramethyl-8,17-dioxo-7-oxatetracyclo[11.3.1.0²,¹¹.0⁵,¹⁰]heptadec-10-en-16-yl]acetate (NP0324355)

Jump To Section:

Identification Spectra BioTaxonomy ChemoTaxonomy Physical properties Links References XML

Record Information

Version

2.0

Created at

2022-09-12 04:23:06 UTC

Updated at

2022-09-12 04:23:06 UTC

NP-MRD ID

NP0324355

Secondary Accession Numbers

None

Natural Product Identification

Common Name

methyl (2r)-2-(acetyloxy)-2-[(1r,2s,5r,6r,13s,14r,16s)-14-(acetyloxy)-6-(furan-3-yl)-1,5,15,15-tetramethyl-8,17-dioxo-7-oxatetracyclo[11.3.1.0²,¹¹.0⁵,¹⁰]heptadec-10-en-16-yl]acetate

Description

SWIETENOLIDE DIACETATE, also known as swietenolide diacetic acid, belongs to the class of organic compounds known as limonoids. These are highly oxygenated, modified terpenoids with a prototypical structure either containing or derived from a precursor with a 4,4,8-trimethyl-17-furanylsteroid skeleton. All naturally occurring citrus limonoids contain a furan ring attached to the D-ring, at C-17, as well as oxygen containing functional groups at C-3, C-4, C-7, C-16 and C-17. methyl (2r)-2-(acetyloxy)-2-[(1r,2s,5r,6r,13s,14r,16s)-14-(acetyloxy)-6-(furan-3-yl)-1,5,15,15-tetramethyl-8,17-dioxo-7-oxatetracyclo[11.3.1.0²,¹¹.0⁵,¹⁰]heptadec-10-en-16-yl]acetate is found in Khaya senegalensis, Swietenia macrophylla and Swietenia mahagoni. methyl (2r)-2-(acetyloxy)-2-[(1r,2s,5r,6r,13s,14r,16s)-14-(acetyloxy)-6-(furan-3-yl)-1,5,15,15-tetramethyl-8,17-dioxo-7-oxatetracyclo[11.3.1.0²,¹¹.0⁵,¹⁰]heptadec-10-en-16-yl]acetate was first documented in 2010 (PMID: 21579475). Based on a literature review very few articles have been published on SWIETENOLIDE DIACETATE.

Structure

MOL SDF PDB SMILES InChI


  Mrv1652309122206232D          

 41 45  0  0  1  0            999 V2000
   -2.3256    1.2639    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5449    1.5306    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9235    0.9878    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0829    0.1783    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1428    1.2545    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.0166    2.0639    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6047    2.6067    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3854    2.3400    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4453    3.4161    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.4785    0.7117    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.2148   -0.0700    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4045   -0.6152    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4721    0.3870    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5811   -0.8093    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.0383   -1.4306    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.3050   -2.2113    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1144   -2.3707    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2378   -2.8326    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.3628   -1.0730    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.1020   -0.7067    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3657    0.0751    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1891    0.0227    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5554   -0.7165    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3787   -0.7689    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7450   -1.5081    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.8357   -0.0821    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.4694    0.6571    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.9265    1.3440    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.6394    2.1174    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2863    2.6294    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9732    2.1724    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.7508    1.3779    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6461    0.7095    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.1031    1.3964    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2798    1.4487    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4564    1.5011    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9994    0.8143    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.2177    1.0780    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.1622    1.9011    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0214   -0.0156    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3228    0.4233    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  3  5  1  0  0  0  0
  5  6  1  6  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  7  9  2  0  0  0  0
 10  5  1  6  0  0  0
 10 11  1  0  0  0  0
 11 12  1  0  0  0  0
 11 13  1  0  0  0  0
 11 14  1  0  0  0  0
 14 15  1  1  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 16 18  2  0  0  0  0
 14 19  1  0  0  0  0
 19 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  2  0  0  0  0
 22 23  1  0  0  0  0
 23 24  1  0  0  0  0
 24 25  2  0  0  0  0
 24 26  1  0  0  0  0
 26 27  1  0  0  0  0
 27 28  1  6  0  0  0
 28 29  1  0  0  0  0
 29 30  2  0  0  0  0
 30 31  1  0  0  0  0
 31 32  1  0  0  0  0
 28 32  2  0  0  0  0
 27 33  1  0  0  0  0
 22 33  1  0  0  0  0
 33 34  1  6  0  0  0
 33 35  1  0  0  0  0
 35 36  1  0  0  0  0
 37 36  1  1  0  0  0
 21 37  1  0  0  0  0
 37 38  1  0  0  0  0
 10 38  1  0  0  0  0
 38 39  1  6  0  0  0
 38 40  1  0  0  0  0
 19 40  1  6  0  0  0
 40 41  2  0  0  0  0
M  END


  Mrv1652309122206232D          

 41 45  0  0  1  0            999 V2000
   -2.3256    1.2639    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5449    1.5306    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9235    0.9878    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0829    0.1783    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1428    1.2545    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.0166    2.0639    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6047    2.6067    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3854    2.3400    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4453    3.4161    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.4785    0.7117    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.2148   -0.0700    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4045   -0.6152    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4721    0.3870    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5811   -0.8093    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.0383   -1.4306    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.3050   -2.2113    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1144   -2.3707    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2378   -2.8326    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.3628   -1.0730    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.1020   -0.7067    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3657    0.0751    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1891    0.0227    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5554   -0.7165    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3787   -0.7689    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7450   -1.5081    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.8357   -0.0821    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.4694    0.6571    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.9265    1.3440    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.6394    2.1174    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2863    2.6294    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9732    2.1724    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.7508    1.3779    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6461    0.7095    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.1031    1.3964    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2798    1.4487    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4564    1.5011    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9994    0.8143    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.2177    1.0780    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.1622    1.9011    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0214   -0.0156    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3228    0.4233    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  3  5  1  0  0  0  0
  5  6  1  6  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  7  9  2  0  0  0  0
 10  5  1  6  0  0  0
 10 11  1  0  0  0  0
 11 12  1  0  0  0  0
 11 13  1  0  0  0  0
 11 14  1  0  0  0  0
 14 15  1  1  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 16 18  2  0  0  0  0
 14 19  1  0  0  0  0
 19 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  2  0  0  0  0
 22 23  1  0  0  0  0
 23 24  1  0  0  0  0
 24 25  2  0  0  0  0
 24 26  1  0  0  0  0
 26 27  1  0  0  0  0
 27 28  1  6  0  0  0
 28 29  1  0  0  0  0
 29 30  2  0  0  0  0
 30 31  1  0  0  0  0
 31 32  1  0  0  0  0
 28 32  2  0  0  0  0
 27 33  1  0  0  0  0
 22 33  1  0  0  0  0
 33 34  1  6  0  0  0
 33 35  1  0  0  0  0
 35 36  1  0  0  0  0
 37 36  1  1  0  0  0
 21 37  1  0  0  0  0
 37 38  1  0  0  0  0
 10 38  1  0  0  0  0
 38 39  1  6  0  0  0
 38 40  1  0  0  0  0
 19 40  1  6  0  0  0
 40 41  2  0  0  0  0
M  END
> <DATABASE_ID>
NP0324355

> <DATABASE_NAME>
NP-MRD

> <SMILES>
COC(=O)[C@H](OC(C)=O)[C@H]1C(C)(C)[C@H](OC(C)=O)[C@@H]2CC3=C4CC(=O)O[C@@H](C5=COC=C5)[C@]4(C)CC[C@@H]3[C@@]1(C)C2=O

> <INCHI_IDENTIFIER>
InChI=1S/C31H38O10/c1-15(32)39-23(28(36)37-7)24-29(3,4)27(40-16(2)33)19-12-18-20(31(24,6)25(19)35)8-10-30(5)21(18)13-22(34)41-26(30)17-9-11-38-14-17/h9,11,14,19-20,23-24,26-27H,8,10,12-13H2,1-7H3/t19-,20+,23-,24+,26+,27-,30-,31-/m1/s1

> <INCHI_KEY>
KCXNWOIFSVEZCW-ZOHPHGJASA-N

> <FORMULA>
C31H38O10

> <MOLECULAR_WEIGHT>
570.635

> <EXACT_MASS>
570.246497424

> <JCHEM_ACCEPTOR_COUNT>
5

> <JCHEM_ATOM_COUNT>
79

> <JCHEM_AVERAGE_POLARIZABILITY>
58.582405705637214

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
0

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
methyl (2R)-2-(acetyloxy)-2-[(1R,2S,5R,6R,13S,14R,16S)-14-(acetyloxy)-6-(furan-3-yl)-1,5,15,15-tetramethyl-8,17-dioxo-7-oxatetracyclo[11.3.1.0^{2,11}.0^{5,10}]heptadec-10-en-16-yl]acetate

> <JCHEM_LOGP>
3.1263753796666673

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
5

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA_STRONGEST_ACIDIC>
18.5756489863079

> <JCHEM_PKA_STRONGEST_BASIC>
-2.8888231864849936

> <JCHEM_POLAR_SURFACE_AREA>
135.41

> <JCHEM_REFRACTIVITY>
142.3815

> <JCHEM_ROTATABLE_BOND_COUNT>
8

> <JCHEM_RULE_OF_FIVE>
0

> <JCHEM_TRADITIONAL_IUPAC>
(R)-(methyl (acetyloxy)[(1R,2S,5R,6R,13S,14R,16S)-14-(acetyloxy)-6-(furan-3-yl)-1,5,15,15-tetramethyl-8,17-dioxo-7-oxatetracyclo[11.3.1.0^{2,11}.0^{5,10}]heptadec-10-en-16-yl]acetate)

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 12-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   12-SEP-22         0                                  
HETATM    1  C   UNK     0      -4.341   2.359   0.000  0.00  0.00           C+0
HETATM    2  O   UNK     0      -2.884   2.857   0.000  0.00  0.00           O+0
HETATM    3  C   UNK     0      -1.724   1.844   0.000  0.00  0.00           C+0
HETATM    4  O   UNK     0      -2.022   0.333   0.000  0.00  0.00           O+0
HETATM    5  C   UNK     0      -0.267   2.342   0.000  0.00  0.00           C+0
HETATM    6  O   UNK     0       0.031   3.853   0.000  0.00  0.00           O+0
HETATM    7  C   UNK     0      -1.129   4.866   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0      -2.586   4.368   0.000  0.00  0.00           C+0
HETATM    9  O   UNK     0      -0.831   6.377   0.000  0.00  0.00           O+0
HETATM   10  C   UNK     0       0.893   1.328   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       0.401  -0.131   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0      -0.755  -1.148   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0      -0.881   0.722   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       1.085  -1.511   0.000  0.00  0.00           C+0
HETATM   15  O   UNK     0       0.071  -2.670   0.000  0.00  0.00           O+0
HETATM   16  C   UNK     0       0.569  -4.128   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       2.080  -4.425   0.000  0.00  0.00           C+0
HETATM   18  O   UNK     0      -0.444  -5.287   0.000  0.00  0.00           O+0
HETATM   19  C   UNK     0       2.544  -2.003   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0       3.924  -1.319   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0       4.416   0.140   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0       5.953   0.042   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0       6.637  -1.338   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0       8.174  -1.435   0.000  0.00  0.00           C+0
HETATM   25  O   UNK     0       8.857  -2.815   0.000  0.00  0.00           O+0
HETATM   26  O   UNK     0       9.027  -0.153   0.000  0.00  0.00           O+0
HETATM   27  C   UNK     0       8.343   1.227   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0       9.196   2.509   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0       8.660   3.953   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0       9.868   4.908   0.000  0.00  0.00           C+0
HETATM   31  O   UNK     0      11.150   4.055   0.000  0.00  0.00           O+0
HETATM   32  C   UNK     0      10.735   2.572   0.000  0.00  0.00           C+0
HETATM   33  C   UNK     0       6.806   1.324   0.000  0.00  0.00           C+0
HETATM   34  C   UNK     0       7.659   2.607   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0       6.122   2.704   0.000  0.00  0.00           C+0
HETATM   36  C   UNK     0       4.585   2.802   0.000  0.00  0.00           C+0
HETATM   37  C   UNK     0       3.732   1.520   0.000  0.00  0.00           C+0
HETATM   38  C   UNK     0       2.273   2.012   0.000  0.00  0.00           C+0
HETATM   39  C   UNK     0       2.169   3.549   0.000  0.00  0.00           C+0
HETATM   40  C   UNK     0       1.907  -0.029   0.000  0.00  0.00           C+0
HETATM   41  O   UNK     0       0.603   0.790   0.000  0.00  0.00           O+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4    5                                                  
CONECT    4    3                                                            
CONECT    5    3    6   10                                                  
CONECT    6    5    7                                                       
CONECT    7    6    8    9                                                  
CONECT    8    7                                                            
CONECT    9    7                                                            
CONECT   10    5   11   38                                                  
CONECT   11   10   12   13   14                                             
CONECT   12   11                                                            
CONECT   13   11                                                            
CONECT   14   11   15   19                                                  
CONECT   15   14   16                                                       
CONECT   16   15   17   18                                                  
CONECT   17   16                                                            
CONECT   18   16                                                            
CONECT   19   14   20   40                                                  
CONECT   20   19   21                                                       
CONECT   21   20   22   37                                                  
CONECT   22   21   23   33                                                  
CONECT   23   22   24                                                       
CONECT   24   23   25   26                                                  
CONECT   25   24                                                            
CONECT   26   24   27                                                       
CONECT   27   26   28   33                                                  
CONECT   28   27   29   32                                                  
CONECT   29   28   30                                                       
CONECT   30   29   31                                                       
CONECT   31   30   32                                                       
CONECT   32   31   28                                                       
CONECT   33   27   22   34   35                                             
CONECT   34   33                                                            
CONECT   35   33   36                                                       
CONECT   36   35   37                                                       
CONECT   37   36   21   38                                                  
CONECT   38   37   10   39   40                                             
CONECT   39   38                                                            
CONECT   40   38   19   41                                                  
CONECT   41   40                                                            
MASTER        0    0    0    0    0    0    0    0   41    0   90    0
END

View in JSmol

Synonyms

Value	Source
SWIETENOLIDE diacetic acid	Generator

Chemical Formula

C₃₁H₃₈O₁₀

Average Mass

570.6350 Da

Monoisotopic Mass

570.24650 Da

IUPAC Name

Not Available

Traditional Name

Not Available

CAS Registry Number

Not Available

SMILES

COC(=O)[C@H](OC(C)=O)[C@H]1C(C)(C)[C@H](OC(C)=O)[C@@H]2CC3=C4CC(=O)O[C@@H](C5=COC=C5)[C@]4(C)CC[C@@H]3[C@@]1(C)C2=O

InChI Identifier

InChI=1S/C31H38O10/c1-15(32)39-23(28(36)37-7)24-29(3,4)27(40-16(2)33)19-12-18-20(31(24,6)25(19)35)8-10-30(5)21(18)13-22(34)41-26(30)17-9-11-38-14-17/h9,11,14,19-20,23-24,26-27H,8,10,12-13H2,1-7H3/t19-,20+,23-,24+,26+,27-,30-,31-/m1/s1

InChI Key

KCXNWOIFSVEZCW-ZOHPHGJASA-N

Experimental Spectra

Not Available

Predicted Spectra

Not Available

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Khaya senegalensis	LOTUS Database	35616633
Swietenia macrophylla	LOTUS Database	35616633
Swietenia mahagoni	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as limonoids. These are highly oxygenated, modified terpenoids with a prototypical structure either containing or derived from a precursor with a 4,4,8-trimethyl-17-furanylsteroid skeleton. All naturally occurring citrus limonoids contain a furan ring attached to the D-ring, at C-17, as well as oxygen containing functional groups at C-3, C-4, C-7, C-16 and C-17.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Prenol lipids

Sub Class

Triterpenoids

Direct Parent

Limonoids

Alternative Parents

Substituents

Mexicanolide
Limonoid skeleton
Naphthopyran
Tetracarboxylic acid or derivatives
Naphthalene
Delta_valerolactone
Delta valerolactone
Pyran
Oxane
Heteroaromatic compound
Methyl ester
Furan
Lactone
Ketone
Carboxylic acid ester
Oxacycle
Organoheterocyclic compound
Carboxylic acid derivative
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Carbonyl group
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

10404649

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

23258997

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

Goh BH, Abdul Kadir H, Abdul Malek SN, Ng SW: Swietenolide diacetate from the seeds of Swietenia macrophylla. Acta Crystallogr Sect E Struct Rep Online. 2010 May 22;66(Pt 6):o1396. doi: 10.1107/S1600536810017733. [PubMed:21579475 ]
LOTUS database [Link]

Showing NP-Card for methyl (2r)-2-(acetyloxy)-2-[(1r,2s,5r,6r,13s,14r,16s)-14-(acetyloxy)-6-(furan-3-yl)-1,5,15,15-tetramethyl-8,17-dioxo-7-oxatetracyclo[11.3.1.0²,¹¹.0⁵,¹⁰]heptadec-10-en-16-yl]acetate (NP0324355)

MOL for NP0324355 (methyl (2r)-2-(acetyloxy)-2-[(1r,2s,5r,6r,13s,14r,16s)-14-(acetyloxy)-6-(furan-3-yl)-1,5,15,15-tetramethyl-8,17-dioxo-7-oxatetracyclo[11.3.1.0²,¹¹.0⁵,¹⁰]heptadec-10-en-16-yl]acetate)

3D MOL for NP0324355 (methyl (2r)-2-(acetyloxy)-2-[(1r,2s,5r,6r,13s,14r,16s)-14-(acetyloxy)-6-(furan-3-yl)-1,5,15,15-tetramethyl-8,17-dioxo-7-oxatetracyclo[11.3.1.0²,¹¹.0⁵,¹⁰]heptadec-10-en-16-yl]acetate)

3D SDF for NP0324355 (methyl (2r)-2-(acetyloxy)-2-[(1r,2s,5r,6r,13s,14r,16s)-14-(acetyloxy)-6-(furan-3-yl)-1,5,15,15-tetramethyl-8,17-dioxo-7-oxatetracyclo[11.3.1.0²,¹¹.0⁵,¹⁰]heptadec-10-en-16-yl]acetate)

3D-SDF for NP0324355 (methyl (2r)-2-(acetyloxy)-2-[(1r,2s,5r,6r,13s,14r,16s)-14-(acetyloxy)-6-(furan-3-yl)-1,5,15,15-tetramethyl-8,17-dioxo-7-oxatetracyclo[11.3.1.0²,¹¹.0⁵,¹⁰]heptadec-10-en-16-yl]acetate)

PDB for NP0324355 (methyl (2r)-2-(acetyloxy)-2-[(1r,2s,5r,6r,13s,14r,16s)-14-(acetyloxy)-6-(furan-3-yl)-1,5,15,15-tetramethyl-8,17-dioxo-7-oxatetracyclo[11.3.1.0²,¹¹.0⁵,¹⁰]heptadec-10-en-16-yl]acetate)

3D PDB for NP0324355 (methyl (2r)-2-(acetyloxy)-2-[(1r,2s,5r,6r,13s,14r,16s)-14-(acetyloxy)-6-(furan-3-yl)-1,5,15,15-tetramethyl-8,17-dioxo-7-oxatetracyclo[11.3.1.0²,¹¹.0⁵,¹⁰]heptadec-10-en-16-yl]acetate)

SMILES for NP0324355 (methyl (2r)-2-(acetyloxy)-2-[(1r,2s,5r,6r,13s,14r,16s)-14-(acetyloxy)-6-(furan-3-yl)-1,5,15,15-tetramethyl-8,17-dioxo-7-oxatetracyclo[11.3.1.0²,¹¹.0⁵,¹⁰]heptadec-10-en-16-yl]acetate)

INCHI for NP0324355 (methyl (2r)-2-(acetyloxy)-2-[(1r,2s,5r,6r,13s,14r,16s)-14-(acetyloxy)-6-(furan-3-yl)-1,5,15,15-tetramethyl-8,17-dioxo-7-oxatetracyclo[11.3.1.0²,¹¹.0⁵,¹⁰]heptadec-10-en-16-yl]acetate)

Structure for NP0324355 (methyl (2r)-2-(acetyloxy)-2-[(1r,2s,5r,6r,13s,14r,16s)-14-(acetyloxy)-6-(furan-3-yl)-1,5,15,15-tetramethyl-8,17-dioxo-7-oxatetracyclo[11.3.1.0²,¹¹.0⁵,¹⁰]heptadec-10-en-16-yl]acetate)

3D Structure for NP0324355 (methyl (2r)-2-(acetyloxy)-2-[(1r,2s,5r,6r,13s,14r,16s)-14-(acetyloxy)-6-(furan-3-yl)-1,5,15,15-tetramethyl-8,17-dioxo-7-oxatetracyclo[11.3.1.0²,¹¹.0⁵,¹⁰]heptadec-10-en-16-yl]acetate)