NP-MRD: Showing NP-Card for (1'r,3'r,8'r,12'z,19'z,21'z,25'r,26's)-18'-hydroxy-5',13',17',26'-tetramethyl-2',10',16',24'-tetraoxaspiro[oxirane-2,27'-tetracyclo[23.2.1.0³,⁸.0⁸,²⁶]octacosane]-4',12',19',21'-tetraene-11',23'-dione (NP0324329)

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Record Information

Version

2.0

Created at

2022-09-12 04:20:48 UTC

Updated at

2022-09-12 04:20:49 UTC

NP-MRD ID

NP0324329

Secondary Accession Numbers

None

Natural Product Identification

Common Name

(1'r,3'r,8'r,12'z,19'z,21'z,25'r,26's)-18'-hydroxy-5',13',17',26'-tetramethyl-2',10',16',24'-tetraoxaspiro[oxirane-2,27'-tetracyclo[23.2.1.0³,⁸.0⁸,²⁶]octacosane]-4',12',19',21'-tetraene-11',23'-dione

Description

RORIDIN P belongs to the class of organic compounds known as trichothecenes. These are sesquiterpene mycotoxins structurally characterized by the presence of an epoxide ring and a benzopyran derivative with a variant number of hydroxyl, acetyl, or other substituents. The most important structural features causing the biological activities of trichothecenes are the 12,13-epoxy ring, the presence of hydroxyl or acetyl groups at appropriate positions on the trichothecene nucleus and the structure and position of the side-chain. (1'r,3'r,8'r,12'z,19'z,21'z,25'r,26's)-18'-hydroxy-5',13',17',26'-tetramethyl-2',10',16',24'-tetraoxaspiro[oxirane-2,27'-tetracyclo[23.2.1.0³,⁸.0⁸,²⁶]octacosane]-4',12',19',21'-tetraene-11',23'-dione is found in Paramyrothecium roridum. Based on a literature review very few articles have been published on RORIDIN P.

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652309122206202D          

 37 41  0  0  1  0            999 V2000
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M  END

     RDKit          3D

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M  END


  Mrv1652309122206202D          

 37 41  0  0  1  0            999 V2000
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    2.7075   -4.0668    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7787   -2.0132    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.5742   -1.7947    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.2990   -1.1472    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7474   -1.8494    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9575   -1.0516    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  2  0  0  0  0
  3  4  1  0  0  0  0
  4  5  1  6  0  0  0
  5  6  1  0  0  0  0
  6  7  1  6  0  0  0
  8  7  1  1  0  0  0
  8  9  1  0  0  0  0
  9 10  1  0  0  0  0
 10 11  2  0  0  0  0
 10 12  1  0  0  0  0
 12 13  2  0  0  0  0
 13 14  1  0  0  0  0
 14 15  2  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 16 18  1  0  0  0  0
 18 19  1  0  0  0  0
 18 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  1  0  0  0  0
 23 24  1  0  0  0  0
 23 25  2  0  0  0  0
 25 26  1  0  0  0  0
 26 27  2  0  0  0  0
 26 28  1  0  0  0  0
 28 29  1  0  0  0  0
 29 30  1  0  0  0  0
  4 30  1  0  0  0  0
 30 31  1  6  0  0  0
 31 32  1  0  0  0  0
  2 32  1  0  0  0  0
 30 33  1  0  0  0  0
  8 33  1  0  0  0  0
 33 34  1  1  0  0  0
 33 35  1  0  0  0  0
  6 35  1  0  0  0  0
 35 36  1  0  0  0  0
 36 37  1  0  0  0  0
 35 37  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0324329

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CC1OCC\C(C)=C/C(=O)OC[C@]23CCC(C)=C[C@H]2O[C@@H]2C[C@@H](OC(=O)\C=C/C=C\C1O)[C@@]3(C)C21CO1

> <INCHI_IDENTIFIER>
InChI=1S/C29H38O8/c1-18-9-11-28-16-34-26(32)14-19(2)10-12-33-20(3)21(30)7-5-6-8-25(31)37-22-15-24(36-23(28)13-18)29(17-35-29)27(22,28)4/h5-8,13-14,20-24,30H,9-12,15-17H2,1-4H3/b7-5-,8-6-,19-14-/t20?,21?,22-,23-,24-,27-,28-,29?/m1/s1

> <INCHI_KEY>
LIZTVRFBEXUQHG-LFGFDUAFSA-N

> <FORMULA>
C29H38O8

> <MOLECULAR_WEIGHT>
514.615

> <EXACT_MASS>
514.256668184

> <JCHEM_ACCEPTOR_COUNT>
6

> <JCHEM_ATOM_COUNT>
75

> <JCHEM_AVERAGE_POLARIZABILITY>
53.87361400230911

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
1

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(1'R,3'R,8'R,12'Z,19'Z,21'Z,25'R,26'S)-18'-hydroxy-5',13',17',26'-tetramethyl-2',10',16',24'-tetraoxaspiro[oxirane-2,27'-tetracyclo[23.2.1.0^{3,8}.0^{8,26}]octacosane]-4',12',19',21'-tetraene-11',23'-dione

> <JCHEM_LOGP>
3.2654564479999983

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
5

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA_STRONGEST_ACIDIC>
13.825575431833922

> <JCHEM_PKA_STRONGEST_BASIC>
-3.312493306115842

> <JCHEM_POLAR_SURFACE_AREA>
103.82000000000001

> <JCHEM_REFRACTIVITY>
138.4212

> <JCHEM_ROTATABLE_BOND_COUNT>
0

> <JCHEM_RULE_OF_FIVE>
0

> <JCHEM_TRADITIONAL_IUPAC>
(1'R,3'R,8'R,12'Z,19'Z,21'Z,25'R,26'S)-18'-hydroxy-5',13',17',26'-tetramethyl-2',10',16',24'-tetraoxaspiro[oxirane-2,27'-tetracyclo[23.2.1.0^{3,8}.0^{8,26}]octacosane]-4',12',19',21'-tetraene-11',23'-dione

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 12-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   12-SEP-22         0                                  
HETATM    1  C   UNK     0       7.707  -7.868   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       6.959  -6.541   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       6.620  -5.432   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       5.373  -4.528   0.000  0.00  0.00           C+0
HETATM    5  O   UNK     0       1.510   0.049   0.000  0.00  0.00           O+0
HETATM    6  C   UNK     0       4.286  -2.092   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       3.814  -3.089   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       3.162  -2.226   0.000  0.00  0.00           C+0
HETATM    9  O   UNK     0       3.510  -0.726   0.000  0.00  0.00           O+0
HETATM   10  C   UNK     0       4.327   0.580   0.000  0.00  0.00           C+0
HETATM   11  O   UNK     0       3.173   1.600   0.000  0.00  0.00           O+0
HETATM   12  C   UNK     0       5.523   1.550   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       6.969   2.079   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       8.509   2.110   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       9.975   1.639   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0      11.209   0.718   0.000  0.00  0.00           C+0
HETATM   17  O   UNK     0      12.321   1.783   0.000  0.00  0.00           O+0
HETATM   18  C   UNK     0      12.077  -0.554   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0      13.474   0.093   0.000  0.00  0.00           C+0
HETATM   20  O   UNK     0      12.485  -2.039   0.000  0.00  0.00           O+0
HETATM   21  C   UNK     0      12.388  -3.576   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0      11.798  -4.999   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0      10.778  -6.152   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0      11.748  -7.348   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0       9.439  -6.912   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0       7.925  -7.196   0.000  0.00  0.00           C+0
HETATM   27  O   UNK     0       8.430  -8.651   0.000  0.00  0.00           O+0
HETATM   28  O   UNK     0       6.401  -6.973   0.000  0.00  0.00           O+0
HETATM   29  C   UNK     0       5.032  -6.267   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0       3.967  -5.156   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0       3.807  -6.687   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0       5.054  -7.591   0.000  0.00  0.00           C+0
HETATM   33  C   UNK     0       3.320  -3.758   0.000  0.00  0.00           C+0
HETATM   34  C   UNK     0       4.805  -3.350   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0       0.558  -2.141   0.000  0.00  0.00           C+0
HETATM   36  C   UNK     0      -1.395  -3.452   0.000  0.00  0.00           C+0
HETATM   37  O   UNK     0      -1.787  -1.963   0.000  0.00  0.00           O+0
CONECT    1    2                                                            
CONECT    2    1    3   32                                                  
CONECT    3    2    4                                                       
CONECT    4    3    5   30                                                  
CONECT    5    4    6                                                       
CONECT    6    5    7   35                                                  
CONECT    7    6    8                                                       
CONECT    8    7    9   33                                                  
CONECT    9    8   10                                                       
CONECT   10    9   11   12                                                  
CONECT   11   10                                                            
CONECT   12   10   13                                                       
CONECT   13   12   14                                                       
CONECT   14   13   15                                                       
CONECT   15   14   16                                                       
CONECT   16   15   17   18                                                  
CONECT   17   16                                                            
CONECT   18   16   19   20                                                  
CONECT   19   18                                                            
CONECT   20   18   21                                                       
CONECT   21   20   22                                                       
CONECT   22   21   23                                                       
CONECT   23   22   24   25                                                  
CONECT   24   23                                                            
CONECT   25   23   26                                                       
CONECT   26   25   27   28                                                  
CONECT   27   26                                                            
CONECT   28   26   29                                                       
CONECT   29   28   30                                                       
CONECT   30   29    4   31   33                                             
CONECT   31   30   32                                                       
CONECT   32   31    2                                                       
CONECT   33   30    8   34   35                                             
CONECT   34   33                                                            
CONECT   35   33    6   36   37                                             
CONECT   36   35   37                                                       
CONECT   37   36   35                                                       
MASTER        0    0    0    0    0    0    0    0   37    0   82    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₂₉H₃₈O₈

Average Mass

514.6150 Da

Monoisotopic Mass

514.25667 Da

IUPAC Name

(1'R,3'R,8'R,12'Z,19'Z,21'Z,25'R,26'S)-18'-hydroxy-5',13',17',26'-tetramethyl-2',10',16',24'-tetraoxaspiro[oxirane-2,27'-tetracyclo[23.2.1.0^{3,8}.0^{8,26}]octacosane]-4',12',19',21'-tetraene-11',23'-dione

Traditional Name

CAS Registry Number

Not Available

SMILES

CC1OCC\C(C)=C/C(=O)OC[C@]23CCC(C)=C[C@H]2O[C@@H]2C[C@@H](OC(=O)\C=C/C=C\C1O)[C@@]3(C)C21CO1

InChI Identifier

InChI=1S/C29H38O8/c1-18-9-11-28-16-34-26(32)14-19(2)10-12-33-20(3)21(30)7-5-6-8-25(31)37-22-15-24(36-23(28)13-18)29(17-35-29)27(22,28)4/h5-8,13-14,20-24,30H,9-12,15-17H2,1-4H3/b7-5-,8-6-,19-14-/t20?,21?,22-,23-,24-,27-,28-,29?/m1/s1

InChI Key

LIZTVRFBEXUQHG-LFGFDUAFSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Myrothecium roridum	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as trichothecenes. These are sesquiterpene mycotoxins structurally characterized by the presence of an epoxide ring and a benzopyran derivative with a variant number of hydroxyl, acetyl, or other substituents. The most important structural features causing the biological activities of trichothecenes are the 12,13-epoxy ring, the presence of hydroxyl or acetyl groups at appropriate positions on the trichothecene nucleus and the structure and position of the side-chain.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Prenol lipids

Sub Class

Sesquiterpenoids

Direct Parent

Trichothecenes

Alternative Parents

Substituents

Trichothecene skeleton
Macrolide
Oxepane
Oxane
Dicarboxylic acid or derivatives
Alpha,beta-unsaturated carboxylic ester
Enoate ester
Secondary alcohol
Lactone
Carboxylic acid ester
Oxacycle
Organoheterocyclic compound
Ether
Oxirane
Dialkyl ether
Carboxylic acid derivative
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Carbonyl group
Alcohol
Aliphatic heteropolycyclic compound

Molecular Framework

Aliphatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	3.27	ChemAxon
pKa (Strongest Acidic)	13.83	ChemAxon
pKa (Strongest Basic)	-3.3	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	6	ChemAxon
Hydrogen Donor Count	1	ChemAxon
Polar Surface Area	103.82 Å²	ChemAxon
Rotatable Bond Count	0	ChemAxon
Refractivity	138.42 m³·mol⁻¹	ChemAxon
Polarizability	53.87 Å³	ChemAxon
Number of Rings	5	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

78445697

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

139588060

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for (1'r,3'r,8'r,12'z,19'z,21'z,25'r,26's)-18'-hydroxy-5',13',17',26'-tetramethyl-2',10',16',24'-tetraoxaspiro[oxirane-2,27'-tetracyclo[23.2.1.0³,⁸.0⁸,²⁶]octacosane]-4',12',19',21'-tetraene-11',23'-dione (NP0324329)

MOL for NP0324329 ((1'r,3'r,8'r,12'z,19'z,21'z,25'r,26's)-18'-hydroxy-5',13',17',26'-tetramethyl-2',10',16',24'-tetraoxaspiro[oxirane-2,27'-tetracyclo[23.2.1.0³,⁸.0⁸,²⁶]octacosane]-4',12',19',21'-tetraene-11',23'-dione)

3D MOL for NP0324329 ((1'r,3'r,8'r,12'z,19'z,21'z,25'r,26's)-18'-hydroxy-5',13',17',26'-tetramethyl-2',10',16',24'-tetraoxaspiro[oxirane-2,27'-tetracyclo[23.2.1.0³,⁸.0⁸,²⁶]octacosane]-4',12',19',21'-tetraene-11',23'-dione)

3D SDF for NP0324329 ((1'r,3'r,8'r,12'z,19'z,21'z,25'r,26's)-18'-hydroxy-5',13',17',26'-tetramethyl-2',10',16',24'-tetraoxaspiro[oxirane-2,27'-tetracyclo[23.2.1.0³,⁸.0⁸,²⁶]octacosane]-4',12',19',21'-tetraene-11',23'-dione)

3D-SDF for NP0324329 ((1'r,3'r,8'r,12'z,19'z,21'z,25'r,26's)-18'-hydroxy-5',13',17',26'-tetramethyl-2',10',16',24'-tetraoxaspiro[oxirane-2,27'-tetracyclo[23.2.1.0³,⁸.0⁸,²⁶]octacosane]-4',12',19',21'-tetraene-11',23'-dione)

PDB for NP0324329 ((1'r,3'r,8'r,12'z,19'z,21'z,25'r,26's)-18'-hydroxy-5',13',17',26'-tetramethyl-2',10',16',24'-tetraoxaspiro[oxirane-2,27'-tetracyclo[23.2.1.0³,⁸.0⁸,²⁶]octacosane]-4',12',19',21'-tetraene-11',23'-dione)

3D PDB for NP0324329 ((1'r,3'r,8'r,12'z,19'z,21'z,25'r,26's)-18'-hydroxy-5',13',17',26'-tetramethyl-2',10',16',24'-tetraoxaspiro[oxirane-2,27'-tetracyclo[23.2.1.0³,⁸.0⁸,²⁶]octacosane]-4',12',19',21'-tetraene-11',23'-dione)

SMILES for NP0324329 ((1'r,3'r,8'r,12'z,19'z,21'z,25'r,26's)-18'-hydroxy-5',13',17',26'-tetramethyl-2',10',16',24'-tetraoxaspiro[oxirane-2,27'-tetracyclo[23.2.1.0³,⁸.0⁸,²⁶]octacosane]-4',12',19',21'-tetraene-11',23'-dione)

INCHI for NP0324329 ((1'r,3'r,8'r,12'z,19'z,21'z,25'r,26's)-18'-hydroxy-5',13',17',26'-tetramethyl-2',10',16',24'-tetraoxaspiro[oxirane-2,27'-tetracyclo[23.2.1.0³,⁸.0⁸,²⁶]octacosane]-4',12',19',21'-tetraene-11',23'-dione)

Structure for NP0324329 ((1'r,3'r,8'r,12'z,19'z,21'z,25'r,26's)-18'-hydroxy-5',13',17',26'-tetramethyl-2',10',16',24'-tetraoxaspiro[oxirane-2,27'-tetracyclo[23.2.1.0³,⁸.0⁸,²⁶]octacosane]-4',12',19',21'-tetraene-11',23'-dione)

3D Structure for NP0324329 ((1'r,3'r,8'r,12'z,19'z,21'z,25'r,26's)-18'-hydroxy-5',13',17',26'-tetramethyl-2',10',16',24'-tetraoxaspiro[oxirane-2,27'-tetracyclo[23.2.1.0³,⁸.0⁸,²⁶]octacosane]-4',12',19',21'-tetraene-11',23'-dione)