NP-MRD: Showing NP-Card for calaxin (NP0322683)

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Record Information

Version

2.0

Created at

2022-09-12 01:36:03 UTC

Updated at

2022-09-12 01:36:03 UTC

NP-MRD ID

NP0322683

Secondary Accession Numbers

None

Natural Product Identification

Common Name

calaxin

Description

Calaxin belongs to the class of organic compounds known as terpene lactones. These are prenol lipids containing a lactone ring. calaxin is found in Heliomeris obscura, Sclerocarpus sessilifolius and Dendroviguiera eriophora. calaxin was first documented in 2017 (PMID: 28883641). Based on a literature review a small amount of articles have been published on Calaxin (PMID: 33845135) (PMID: 31286071) (PMID: 31240264) (PMID: 29386625).

Structure

MOL 3D MOL SDF PDB SMILES InChI

     RDKit          3D

 45 47  0  0  0  0  0  0  0  0999 V2000
    4.4369   -1.1694   -0.9546 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9352   -0.8981    0.2367 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.8217   -1.0586    1.4140 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5762   -0.4586    0.4224 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1370   -0.2096    1.5833 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.6539   -0.2687   -0.5674 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.3309    0.1596   -0.3827 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.6450   -0.9612   -0.7265 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1333   -1.6706    0.5157 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.2182   -2.8139    0.9016 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1888   -0.6833    1.5232 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3993   -0.0411    1.3367 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2727   -1.0364    1.1589 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5491   -2.0924    0.4771 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0453   -3.1206   -0.0220 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5752    1.4240    1.3539 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6880    1.9407    2.2367 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8004    2.2226    0.6370 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4348    1.8479   -0.7573 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.5048    3.0163   -1.6033 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8353    2.6321   -2.7634 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0680    3.1228   -3.9181 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.1416    1.6033   -2.4136 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8985    1.0065   -3.2816 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0085    1.4772   -0.9485 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.7992   -1.0568   -1.8312 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.4316   -1.4942   -1.1221 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.3278   -1.6778    2.2167 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.7810   -1.5584    1.1497 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.0665   -0.0949    1.9056 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.2431    0.2959    0.7402 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4151   -0.6887   -1.4391 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0282   -1.7466   -1.2642 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.4287   -2.4701    1.7250 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8439   -3.6373    1.2929 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.4201   -3.1068    0.0496 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3198   -0.9782    1.4949 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0568    2.9205    1.9397 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5190    1.2361    2.2818 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3136    2.0602    3.2961 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4810    3.1195    1.1229 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1498    1.1615   -1.2358 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.8321    1.2569   -4.3304 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.6305    0.2419   -3.0550 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.5848    2.2467   -0.3959 H   0  0  0  0  0  0  0  0  0  0  0  0
  3  2  1  0
  2  1  2  3
  2  4  1  0
  4  5  2  0
  4  6  1  0
  6  7  1  0
  7  8  1  0
  8  9  1  0
  9 10  1  1
  9 11  1  0
 11 12  1  0
 12 13  2  0
 13 14  1  0
 14 15  2  0
 12 16  1  0
 16 17  1  0
 16 18  2  0
 18 19  1  0
 19 20  1  0
 20 21  1  0
 21 22  2  0
 21 23  1  0
 23 24  2  3
 23 25  1  0
 25  7  1  0
 14  9  1  0
 25 19  1  0
  3 28  1  0
  3 29  1  0
  3 30  1  0
  1 26  1  0
  1 27  1  0
  7 31  1  1
  8 32  1  0
  8 33  1  0
 10 34  1  0
 10 35  1  0
 10 36  1  0
 13 37  1  0
 17 38  1  0
 17 39  1  0
 17 40  1  0
 18 41  1  0
 19 42  1  6
 24 43  1  0
 24 44  1  0
 25 45  1  1
M  END


  Mrv1652309122203362D          

 25 27  0  0  1  0            999 V2000
    0.5371   -2.4297    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.2015   -1.6761    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6190   -1.5898    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6865   -1.0086    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5069   -1.0949    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.3509   -0.2549    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.8358    0.4125    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.6204    0.1576    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4051    0.4125    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.8900   -0.2549    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1351    1.4924    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.4051    2.5724    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8900    1.9049    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8900    1.0799    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6746    0.8250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.6204    2.8273    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6204    3.6523    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8358    2.5724    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3509    1.9049    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.4337    2.1599    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9187    1.4924    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7437    1.4924    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4337    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6887    0.0404    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3509    1.0799    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
  1  2  2  0  0  0  0
  2  3  1  0  0  0  0
  2  4  1  0  0  0  0
  4  5  2  0  0  0  0
  4  6  1  0  0  0  0
  7  6  1  1  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  1  6  0  0  0
  9 11  1  0  0  0  0
 11 12  1  0  0  0  0
 12 13  2  0  0  0  0
 13 14  1  0  0  0  0
  9 14  1  0  0  0  0
 14 15  2  0  0  0  0
 12 16  1  0  0  0  0
 16 17  1  0  0  0  0
 16 18  2  0  0  0  0
 18 19  1  0  0  0  0
 19 20  1  6  0  0  0
 20 21  1  0  0  0  0
 21 22  2  0  0  0  0
 21 23  1  0  0  0  0
 23 24  2  0  0  0  0
 25 23  1  1  0  0  0
 19 25  1  0  0  0  0
  7 25  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0322683

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CC(=C)C(=O)O[C@@H]1C[C@@]2(C)OC(=CC2=O)\C(C)=C/[C@H]2OC(=O)C(=C)[C@H]12

> <INCHI_IDENTIFIER>
InChI=1S/C19H20O6/c1-9(2)17(21)24-14-8-19(5)15(20)7-12(25-19)10(3)6-13-16(14)11(4)18(22)23-13/h6-7,13-14,16H,1,4,8H2,2-3,5H3/b10-6-/t13-,14-,16+,19-/m1/s1

> <INCHI_KEY>
RYBHZNMPMHOBAR-IRNKKCRZSA-N

> <FORMULA>
C19H20O6

> <MOLECULAR_WEIGHT>
344.363

> <EXACT_MASS>
344.125988364

> <JCHEM_ACCEPTOR_COUNT>
4

> <JCHEM_ATOM_COUNT>
45

> <JCHEM_AVERAGE_POLARIZABILITY>
34.94481977783687

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
0

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
(2Z,4R,8R,9R,11R)-2,11-dimethyl-7-methylidene-6,12-dioxo-5,14-dioxatricyclo[9.2.1.0^{4,8}]tetradeca-1(13),2-dien-9-yl 2-methylprop-2-enoate

> <JCHEM_LOGP>
2.6839367543333337

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
3

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA_STRONGEST_BASIC>
-4.881020033563633

> <JCHEM_POLAR_SURFACE_AREA>
78.9

> <JCHEM_REFRACTIVITY>
90.5536

> <JCHEM_ROTATABLE_BOND_COUNT>
3

> <JCHEM_RULE_OF_FIVE>
1

> <JCHEM_TRADITIONAL_IUPAC>
(2Z,4R,8R,9R,11R)-2,11-dimethyl-7-methylidene-6,12-dioxo-5,14-dioxatricyclo[9.2.1.0^{4,8}]tetradeca-1(13),2-dien-9-yl 2-methylprop-2-enoate

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 12-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   12-SEP-22         0                                  
HETATM    1  C   UNK     0       1.003  -4.535   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       0.376  -3.129   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      -1.155  -2.968   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       1.281  -1.883   0.000  0.00  0.00           C+0
HETATM    5  O   UNK     0       2.813  -2.044   0.000  0.00  0.00           O+0
HETATM    6  O   UNK     0       0.655  -0.476   0.000  0.00  0.00           O+0
HETATM    7  C   UNK     0       1.560   0.770   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       3.025   0.294   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       4.489   0.770   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       5.395  -0.476   0.000  0.00  0.00           C+0
HETATM   11  O   UNK     0       3.985   2.786   0.000  0.00  0.00           O+0
HETATM   12  C   UNK     0       4.489   4.802   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       5.395   3.556   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       5.395   2.016   0.000  0.00  0.00           C+0
HETATM   15  O   UNK     0       6.859   1.540   0.000  0.00  0.00           O+0
HETATM   16  C   UNK     0       3.025   5.278   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       3.025   6.818   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       1.560   4.802   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       0.655   3.556   0.000  0.00  0.00           C+0
HETATM   20  O   UNK     0      -0.810   4.032   0.000  0.00  0.00           O+0
HETATM   21  C   UNK     0      -1.715   2.786   0.000  0.00  0.00           C+0
HETATM   22  O   UNK     0      -3.255   2.786   0.000  0.00  0.00           O+0
HETATM   23  C   UNK     0      -0.810   1.540   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0      -1.286   0.075   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0       0.655   2.016   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3    4                                                  
CONECT    3    2                                                            
CONECT    4    2    5    6                                                  
CONECT    5    4                                                            
CONECT    6    4    7                                                       
CONECT    7    6    8   25                                                  
CONECT    8    7    9                                                       
CONECT    9    8   10   11   14                                             
CONECT   10    9                                                            
CONECT   11    9   12                                                       
CONECT   12   11   13   16                                                  
CONECT   13   12   14                                                       
CONECT   14   13    9   15                                                  
CONECT   15   14                                                            
CONECT   16   12   17   18                                                  
CONECT   17   16                                                            
CONECT   18   16   19                                                       
CONECT   19   18   20   25                                                  
CONECT   20   19   21                                                       
CONECT   21   20   22   23                                                  
CONECT   22   21                                                            
CONECT   23   21   24   25                                                  
CONECT   24   23                                                            
CONECT   25   23   19    7                                                  
MASTER        0    0    0    0    0    0    0    0   25    0   54    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₁₉H₂₀O₆

Average Mass

344.3630 Da

Monoisotopic Mass

344.12599 Da

IUPAC Name

(2Z,4R,8R,9R,11R)-2,11-dimethyl-7-methylidene-6,12-dioxo-5,14-dioxatricyclo[9.2.1.0^{4,8}]tetradeca-1(13),2-dien-9-yl 2-methylprop-2-enoate

Traditional Name

(2Z,4R,8R,9R,11R)-2,11-dimethyl-7-methylidene-6,12-dioxo-5,14-dioxatricyclo[9.2.1.0^{4,8}]tetradeca-1(13),2-dien-9-yl 2-methylprop-2-enoate

CAS Registry Number

Not Available

SMILES

CC(=C)C(=O)O[C@@H]1C[C@@]2(C)OC(=CC2=O)\C(C)=C/[C@H]2OC(=O)C(=C)[C@H]12

InChI Identifier

InChI=1S/C19H20O6/c1-9(2)17(21)24-14-8-19(5)15(20)7-12(25-19)10(3)6-13-16(14)11(4)18(22)23-13/h6-7,13-14,16H,1,4,8H2,2-3,5H3/b10-6-/t13-,14-,16+,19-/m1/s1

InChI Key

RYBHZNMPMHOBAR-IRNKKCRZSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Heliomeris obscura	LOTUS Database	35616633
Sclerocarpus sessilifolius	LOTUS Database	35616633
Viguiera eriophora	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as terpene lactones. These are prenol lipids containing a lactone ring.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Prenol lipids

Sub Class

Terpene lactones

Direct Parent

Terpene lactones

Alternative Parents

Substituents

Terpene lactone
Sesquiterpenoid
Dicarboxylic acid or derivatives
3-furanone
Gamma butyrolactone
Dihydrofuran
Tetrahydrofuran
Enoate ester
Alpha,beta-unsaturated carboxylic ester
Vinylogous ester
Lactone
Ketone
Carboxylic acid ester
Oxacycle
Organoheterocyclic compound
Carboxylic acid derivative
Organooxygen compound
Hydrocarbon derivative
Organic oxide
Carbonyl group
Organic oxygen compound
Aliphatic heteropolycyclic compound

Molecular Framework

Aliphatic heteropolycyclic compounds

External Descriptors

sesquiterpenoid (CHEBI:3302 )
Germacrenes (C09353 )

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	2.68	ChemAxon
pKa (Strongest Basic)	-4.9	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	4	ChemAxon
Hydrogen Donor Count	0	ChemAxon
Polar Surface Area	78.9 Å²	ChemAxon
Rotatable Bond Count	3	ChemAxon
Refractivity	90.55 m³·mol⁻¹	ChemAxon
Polarizability	34.94 Å³	ChemAxon
Number of Rings	3	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

C00003227

Chemspider ID

4444778

KEGG Compound ID

C09353

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

5281431

PDB ID

Not Available

ChEBI ID

3302

Good Scents ID

Not Available

References

General References

Huan P, Cui M, Wang Q, Liu B: CRISPR/Cas9-mediated mutagenesis reveals the roles of calaxin in gastropod larval cilia. Gene. 2021 Jun 30;787:145640. doi: 10.1016/j.gene.2021.145640. Epub 2021 Apr 21. [PubMed:33845135 ]
Sasaki K, Shiba K, Nakamura A, Kawano N, Satouh Y, Yamaguchi H, Morikawa M, Shibata D, Yanase R, Jokura K, Nomura M, Miyado M, Takada S, Ueno H, Nonaka S, Baba T, Ikawa M, Kikkawa M, Miyado K, Inaba K: Erratum: Publisher Correction: Calaxin is required for cilia-driven determination of vertebrate laterality. Commun Biol. 2019 Jul 4;2:254. doi: 10.1038/s42003-019-0512-5. eCollection 2019. [PubMed:31286071 ]
Sasaki K, Shiba K, Nakamura A, Kawano N, Satouh Y, Yamaguchi H, Morikawa M, Shibata D, Yanase R, Jokura K, Nomura M, Miyado M, Takada S, Ueno H, Nonaka S, Baba T, Ikawa M, Kikkawa M, Miyado K, Inaba K: Calaxin is required for cilia-driven determination of vertebrate laterality. Commun Biol. 2019 Jun 20;2:226. doi: 10.1038/s42003-019-0462-y. eCollection 2019. [PubMed:31240264 ]
Shojima T, Hou F, Takahashi Y, Matsumura Y, Okai M, Nakamura A, Mizuno K, Inaba K, Kojima M, Miyakawa T, Tanokura M: Crystal structure of a Ca(2+)-dependent regulator of flagellar motility reveals the open-closed structural transition. Sci Rep. 2018 Jan 31;8(1):2014. doi: 10.1038/s41598-018-19898-7. [PubMed:29386625 ]
Mizuno K, Shiba K, Yaguchi J, Shibata D, Yaguchi S, Pruliere G, Chenevert J, Inaba K: Calaxin establishes basal body orientation and coordinates movement of monocilia in sea urchin embryos. Sci Rep. 2017 Sep 7;7(1):10751. doi: 10.1038/s41598-017-10822-z. [PubMed:28883641 ]
LOTUS database [Link]

Showing NP-Card for calaxin (NP0322683)

MOL for NP0322683 (calaxin)

3D MOL for NP0322683 (calaxin)

3D SDF for NP0322683 (calaxin)

3D-SDF for NP0322683 (calaxin)

PDB for NP0322683 (calaxin)

3D PDB for NP0322683 (calaxin)

SMILES for NP0322683 (calaxin)

INCHI for NP0322683 (calaxin)

Structure for NP0322683 (calaxin)

3D Structure for NP0322683 (calaxin)