NP-MRD: Showing NP-Card for methyl (4s,4as,6s,7r,7as)-6-[(1s,4as,7s,7as)-7-methyl-1-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyran-4-carbonyloxy]-7-methyl-3-oxo-hexahydro-1h-cyclopenta[c]pyran-4-carboxylate (NP0318899)

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Record Information

Version

2.0

Created at

2022-09-11 19:39:49 UTC

Updated at

2022-09-11 19:39:49 UTC

NP-MRD ID

NP0318899

Secondary Accession Numbers

None

Natural Product Identification

Common Name

methyl (4s,4as,6s,7r,7as)-6-[(1s,4as,7s,7as)-7-methyl-1-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyran-4-carbonyloxy]-7-methyl-3-oxo-hexahydro-1h-cyclopenta[c]pyran-4-carboxylate

Description

Laciniatoside III belongs to the class of organic compounds known as iridoid o-glycosides. These are iridoid monoterpenes containing a glycosyl (usually a pyranosyl) moiety linked to the iridoid skeleton. methyl (4s,4as,6s,7r,7as)-6-[(1s,4as,7s,7as)-7-methyl-1-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyran-4-carbonyloxy]-7-methyl-3-oxo-hexahydro-1h-cyclopenta[c]pyran-4-carboxylate is found in Dipsacus laciniatus. Based on a literature review very few articles have been published on Laciniatoside III.

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652309112221392D          

 40 44  0  0  1  0            999 V2000
    6.8809    5.9985    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0559    5.9985    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.6434    5.2840    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0559    4.5695    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.8184    5.2840    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.4059    5.9985    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.8184    6.7130    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.5809    5.9985    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.1684    5.2840    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5809    4.5695    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.4059    4.5695    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.6608    3.7849    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9934    3.3000    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.9934    2.4750    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.2789    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5645    2.4750    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.2789    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9934    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9934    0.0000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.2789   -0.4125    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.2789   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.9934   -1.6500    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.7079   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.4223   -1.6500    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    6.1368   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.8513   -1.6500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.4223   -2.4750    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    6.1368   -2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.7079   -2.8875    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.7079   -3.7125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.9934   -2.4750    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.2789   -2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.5645    0.0000    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.7798   -0.2549    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.5249   -1.0396    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2949    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7798    1.0799    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5645    0.8250    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.3260    3.7849    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.5413    3.5300    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  5  3  1  6  0  0  0
  5  6  1  0  0  0  0
  6  7  2  0  0  0  0
  6  8  1  0  0  0  0
  8  9  1  0  0  0  0
 10  9  1  1  0  0  0
 10 11  1  0  0  0  0
  5 11  1  0  0  0  0
 11 12  1  1  0  0  0
 12 13  1  0  0  0  0
 13 14  1  6  0  0  0
 14 15  1  0  0  0  0
 15 16  2  0  0  0  0
 15 17  1  0  0  0  0
 17 18  2  0  0  0  0
 18 19  1  0  0  0  0
 19 20  1  0  0  0  0
 20 21  1  1  0  0  0
 22 21  1  6  0  0  0
 22 23  1  0  0  0  0
 23 24  1  0  0  0  0
 24 25  1  6  0  0  0
 25 26  1  0  0  0  0
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 27 28  1  1  0  0  0
 27 29  1  0  0  0  0
 29 30  1  6  0  0  0
 29 31  1  0  0  0  0
 22 31  1  0  0  0  0
 31 32  1  1  0  0  0
 20 33  1  0  0  0  0
 33 34  1  1  0  0  0
 34 35  1  1  0  0  0
 34 36  1  0  0  0  0
 36 37  1  0  0  0  0
 38 37  1  6  0  0  0
 17 38  1  0  0  0  0
 33 38  1  0  0  0  0
 13 39  1  0  0  0  0
 10 39  1  0  0  0  0
 39 40  1  6  0  0  0
M  END

     RDKit          3D

 78 82  0  0  0  0  0  0  0  0999 V2000
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    6.1221    1.2763   -1.8663 C   0  0  1  0  0  0  0  0  0  0  0  0
    6.2118   -0.0081   -2.5731 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.3363   -0.0431   -3.8192 O   0  0  0  0  0  0  0  0  0  0  0  0
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    6.4714   -1.0825   -0.4583 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7149   -0.0122    0.2568 C   0  0  1  0  0  0  0  0  0  0  0  0
    5.3843    1.1875   -0.5633 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.8880    1.2430   -0.7152 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4135   -0.0951   -0.2245 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.1123   -0.0368    0.3239 O   0  0  0  0  0  0  0  0  0  0  0  0
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   -1.1439   -2.7664   -0.7637 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4150   -1.4737   -0.0918 C   0  0  2  0  0  0  0  0  0  0  0  0
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    4.1323   -0.1808    2.1773 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.6796    3.3580   -1.4579 H   0  0  0  0  0  0  0  0  0  0  0  0
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    5.6174    2.0613   -2.4858 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.2080   -2.0785   -0.0171 H   0  0  0  0  0  0  0  0  0  0  0  0
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    5.6696    2.1079    0.0225 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.4253    2.0997   -0.1959 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.6704    1.3106   -1.8119 H   0  0  0  0  0  0  0  0  0  0  0  0
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   -6.7945   -0.3342   -1.3596 H   0  0  0  0  0  0  0  0  0  0  0  0
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  2  3  1  0
  3  4  2  0
  3  5  1  0
  5 11  1  0
 11 12  1  0
 12 13  1  0
 13 14  1  0
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 29 30  1  0
 29 31  1  0
 31 32  1  0
 20 33  1  0
 33 34  1  0
 34 35  1  0
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 13 39  1  0
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 10  9  1  0
  9  8  1  0
  8  6  1  0
  6  7  2  0
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 38 17  1  0
 31 22  1  0
 38 33  1  0
  1 41  1  0
  1 42  1  0
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 39 75  1  1
 40 76  1  0
 40 77  1  0
 40 78  1  0
 10 47  1  1
  9 45  1  0
  9 46  1  0
M  END


  Mrv1652309112221392D          

 40 44  0  0  1  0            999 V2000
    6.8809    5.9985    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0559    5.9985    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.6434    5.2840    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0559    4.5695    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.8184    5.2840    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.4059    5.9985    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.8184    6.7130    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.5809    5.9985    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.1684    5.2840    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5809    4.5695    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.4059    4.5695    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.6608    3.7849    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9934    3.3000    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.9934    2.4750    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.2789    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5645    2.4750    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
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    4.7079   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.4223   -1.6500    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    6.1368   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.8513   -1.6500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.4223   -2.4750    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    6.1368   -2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.7079   -2.8875    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.7079   -3.7125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.9934   -2.4750    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.2789   -2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.5645    0.0000    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.7798   -0.2549    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.5249   -1.0396    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2949    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7798    1.0799    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5645    0.8250    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.3260    3.7849    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.5413    3.5300    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  5  3  1  6  0  0  0
  5  6  1  0  0  0  0
  6  7  2  0  0  0  0
  6  8  1  0  0  0  0
  8  9  1  0  0  0  0
 10  9  1  1  0  0  0
 10 11  1  0  0  0  0
  5 11  1  0  0  0  0
 11 12  1  1  0  0  0
 12 13  1  0  0  0  0
 13 14  1  6  0  0  0
 14 15  1  0  0  0  0
 15 16  2  0  0  0  0
 15 17  1  0  0  0  0
 17 18  2  0  0  0  0
 18 19  1  0  0  0  0
 19 20  1  0  0  0  0
 20 21  1  1  0  0  0
 22 21  1  6  0  0  0
 22 23  1  0  0  0  0
 23 24  1  0  0  0  0
 24 25  1  6  0  0  0
 25 26  1  0  0  0  0
 24 27  1  0  0  0  0
 27 28  1  1  0  0  0
 27 29  1  0  0  0  0
 29 30  1  6  0  0  0
 29 31  1  0  0  0  0
 22 31  1  0  0  0  0
 31 32  1  1  0  0  0
 20 33  1  0  0  0  0
 33 34  1  1  0  0  0
 34 35  1  1  0  0  0
 34 36  1  0  0  0  0
 36 37  1  0  0  0  0
 38 37  1  6  0  0  0
 17 38  1  0  0  0  0
 33 38  1  0  0  0  0
 13 39  1  0  0  0  0
 10 39  1  0  0  0  0
 39 40  1  6  0  0  0
M  END
> <DATABASE_ID>
NP0318899

> <DATABASE_NAME>
NP-MRD

> <SMILES>
COC(=O)[C@@H]1[C@H]2C[C@H](OC(=O)C3=CO[C@@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@H]4[C@@H](C)CC[C@H]34)[C@H](C)[C@H]2COC1=O

> <INCHI_IDENTIFIER>
InChI=1S/C27H38O13/c1-10-4-5-12-15(9-37-26(18(10)12)40-27-22(31)21(30)20(29)17(7-28)39-27)23(32)38-16-6-13-14(11(16)2)8-36-25(34)19(13)24(33)35-3/h9-14,16-22,26-31H,4-8H2,1-3H3/t10-,11+,12+,13-,14+,16-,17+,18-,19-,20+,21-,22+,26-,27-/m0/s1

> <INCHI_KEY>
RYNMWHZLOPICQA-SCWHPQJBSA-N

> <FORMULA>
C27H38O13

> <MOLECULAR_WEIGHT>
570.588

> <EXACT_MASS>
570.231241284

> <JCHEM_ACCEPTOR_COUNT>
10

> <JCHEM_ATOM_COUNT>
78

> <JCHEM_AVERAGE_POLARIZABILITY>
57.39033512301274

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
4

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
methyl (4S,4aS,6S,7R,7aS)-6-[(1S,4aS,7S,7aS)-7-methyl-1-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1H,4aH,5H,6H,7H,7aH-cyclopenta[c]pyran-4-carbonyloxy]-7-methyl-3-oxo-octahydrocyclopenta[c]pyran-4-carboxylate

> <JCHEM_LOGP>
0.07597828966666614

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
5

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
12.867278494381523

> <JCHEM_PKA_STRONGEST_ACIDIC>
12.146566635919182

> <JCHEM_PKA_STRONGEST_BASIC>
-2.9810847601512

> <JCHEM_POLAR_SURFACE_AREA>
187.51

> <JCHEM_REFRACTIVITY>
131.55060000000003

> <JCHEM_ROTATABLE_BOND_COUNT>
8

> <JCHEM_RULE_OF_FIVE>
0

> <JCHEM_TRADITIONAL_IUPAC>
methyl (4S,4aS,6S,7R,7aS)-6-[(1S,4aS,7S,7aS)-7-methyl-1-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1H,4aH,5H,6H,7H,7aH-cyclopenta[c]pyran-4-carbonyloxy]-7-methyl-3-oxo-hexahydro-1H-cyclopenta[c]pyran-4-carboxylate

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 11-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   11-SEP-22         0                                  
HETATM    1  C   UNK     0      12.844  11.197   0.000  0.00  0.00           C+0
HETATM    2  O   UNK     0      11.304  11.197   0.000  0.00  0.00           O+0
HETATM    3  C   UNK     0      10.534   9.863   0.000  0.00  0.00           C+0
HETATM    4  O   UNK     0      11.304   8.530   0.000  0.00  0.00           O+0
HETATM    5  C   UNK     0       8.994   9.863   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       8.224  11.197   0.000  0.00  0.00           C+0
HETATM    7  O   UNK     0       8.994  12.531   0.000  0.00  0.00           O+0
HETATM    8  O   UNK     0       6.684  11.197   0.000  0.00  0.00           O+0
HETATM    9  C   UNK     0       5.914   9.863   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       6.684   8.530   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       8.224   8.530   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       8.700   7.065   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       7.454   6.160   0.000  0.00  0.00           C+0
HETATM   14  O   UNK     0       7.454   4.620   0.000  0.00  0.00           O+0
HETATM   15  C   UNK     0       6.121   3.850   0.000  0.00  0.00           C+0
HETATM   16  O   UNK     0       4.787   4.620   0.000  0.00  0.00           O+0
HETATM   17  C   UNK     0       6.121   2.310   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       7.454   1.540   0.000  0.00  0.00           C+0
HETATM   19  O   UNK     0       7.454   0.000   0.000  0.00  0.00           O+0
HETATM   20  C   UNK     0       6.121  -0.770   0.000  0.00  0.00           C+0
HETATM   21  O   UNK     0       6.121  -2.310   0.000  0.00  0.00           O+0
HETATM   22  C   UNK     0       7.454  -3.080   0.000  0.00  0.00           C+0
HETATM   23  O   UNK     0       8.788  -2.310   0.000  0.00  0.00           O+0
HETATM   24  C   UNK     0      10.122  -3.080   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0      11.455  -2.310   0.000  0.00  0.00           C+0
HETATM   26  O   UNK     0      12.789  -3.080   0.000  0.00  0.00           O+0
HETATM   27  C   UNK     0      10.122  -4.620   0.000  0.00  0.00           C+0
HETATM   28  O   UNK     0      11.455  -5.390   0.000  0.00  0.00           O+0
HETATM   29  C   UNK     0       8.788  -5.390   0.000  0.00  0.00           C+0
HETATM   30  O   UNK     0       8.788  -6.930   0.000  0.00  0.00           O+0
HETATM   31  C   UNK     0       7.454  -4.620   0.000  0.00  0.00           C+0
HETATM   32  O   UNK     0       6.121  -5.390   0.000  0.00  0.00           O+0
HETATM   33  C   UNK     0       4.787   0.000   0.000  0.00  0.00           C+0
HETATM   34  C   UNK     0       3.322  -0.476   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0       2.846  -1.941   0.000  0.00  0.00           C+0
HETATM   36  C   UNK     0       2.417   0.770   0.000  0.00  0.00           C+0
HETATM   37  C   UNK     0       3.322   2.016   0.000  0.00  0.00           C+0
HETATM   38  C   UNK     0       4.787   1.540   0.000  0.00  0.00           C+0
HETATM   39  C   UNK     0       6.208   7.065   0.000  0.00  0.00           C+0
HETATM   40  C   UNK     0       4.744   6.589   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4    5                                                  
CONECT    4    3                                                            
CONECT    5    3    6   11                                                  
CONECT    6    5    7    8                                                  
CONECT    7    6                                                            
CONECT    8    6    9                                                       
CONECT    9    8   10                                                       
CONECT   10    9   11   39                                                  
CONECT   11   10    5   12                                                  
CONECT   12   11   13                                                       
CONECT   13   12   14   39                                                  
CONECT   14   13   15                                                       
CONECT   15   14   16   17                                                  
CONECT   16   15                                                            
CONECT   17   15   18   38                                                  
CONECT   18   17   19                                                       
CONECT   19   18   20                                                       
CONECT   20   19   21   33                                                  
CONECT   21   20   22                                                       
CONECT   22   21   23   31                                                  
CONECT   23   22   24                                                       
CONECT   24   23   25   27                                                  
CONECT   25   24   26                                                       
CONECT   26   25                                                            
CONECT   27   24   28   29                                                  
CONECT   28   27                                                            
CONECT   29   27   30   31                                                  
CONECT   30   29                                                            
CONECT   31   29   22   32                                                  
CONECT   32   31                                                            
CONECT   33   20   34   38                                                  
CONECT   34   33   35   36                                                  
CONECT   35   34                                                            
CONECT   36   34   37                                                       
CONECT   37   36   38                                                       
CONECT   38   37   17   33                                                  
CONECT   39   13   10   40                                                  
CONECT   40   39                                                            
MASTER        0    0    0    0    0    0    0    0   40    0   88    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₂₇H₃₈O₁₃

Average Mass

570.5880 Da

Monoisotopic Mass

570.23124 Da

IUPAC Name

methyl (4S,4aS,6S,7R,7aS)-6-[(1S,4aS,7S,7aS)-7-methyl-1-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1H,4aH,5H,6H,7H,7aH-cyclopenta[c]pyran-4-carbonyloxy]-7-methyl-3-oxo-octahydrocyclopenta[c]pyran-4-carboxylate

Traditional Name

CAS Registry Number

Not Available

SMILES

COC(=O)[C@@H]1[C@H]2C[C@H](OC(=O)C3=CO[C@@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@H]4[C@@H](C)CC[C@H]34)[C@H](C)[C@H]2COC1=O

InChI Identifier

InChI=1S/C27H38O13/c1-10-4-5-12-15(9-37-26(18(10)12)40-27-22(31)21(30)20(29)17(7-28)39-27)23(32)38-16-6-13-14(11(16)2)8-36-25(34)19(13)24(33)35-3/h9-14,16-22,26-31H,4-8H2,1-3H3/t10-,11+,12+,13-,14+,16-,17+,18-,19-,20+,21-,22+,26-,27-/m0/s1

InChI Key

RYNMWHZLOPICQA-SCWHPQJBSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Dipsacus laciniatus	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as iridoid o-glycosides. These are iridoid monoterpenes containing a glycosyl (usually a pyranosyl) moiety linked to the iridoid skeleton.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Prenol lipids

Sub Class

Terpene glycosides

Direct Parent

Iridoid O-glycosides

Alternative Parents

Substituents

Iridoid o-glycoside
Terpene lactone
Hexose monosaccharide
Glycosyl compound
Iridoid-skeleton
O-glycosyl compound
Monoterpenoid
Tricarboxylic acid or derivatives
Delta valerolactone
Delta_valerolactone
Monosaccharide
Oxane
1,3-dicarbonyl compound
Methyl ester
Enoate ester
Alpha,beta-unsaturated carboxylic ester
Vinylogous ester
Secondary alcohol
Carboxylic acid ester
Lactone
Polyol
Carboxylic acid derivative
Oxacycle
Organoheterocyclic compound
Acetal
Organic oxide
Organic oxygen compound
Alcohol
Hydrocarbon derivative
Carbonyl group
Organooxygen compound
Primary alcohol
Aliphatic heteropolycyclic compound

Molecular Framework

Aliphatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	0.076	ChemAxon
pKa (Strongest Acidic)	12.15	ChemAxon
pKa (Strongest Basic)	-3	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	10	ChemAxon
Hydrogen Donor Count	4	ChemAxon
Polar Surface Area	187.51 Å²	ChemAxon
Rotatable Bond Count	8	ChemAxon
Refractivity	131.55 m³·mol⁻¹	ChemAxon
Polarizability	57.39 Å³	ChemAxon
Number of Rings	5	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	Yes	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

101419892

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for methyl (4s,4as,6s,7r,7as)-6-[(1s,4as,7s,7as)-7-methyl-1-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyran-4-carbonyloxy]-7-methyl-3-oxo-hexahydro-1h-cyclopenta[c]pyran-4-carboxylate (NP0318899)

MOL for NP0318899 (methyl (4s,4as,6s,7r,7as)-6-[(1s,4as,7s,7as)-7-methyl-1-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyran-4-carbonyloxy]-7-methyl-3-oxo-hexahydro-1h-cyclopenta[c]pyran-4-carboxylate)

3D MOL for NP0318899 (methyl (4s,4as,6s,7r,7as)-6-[(1s,4as,7s,7as)-7-methyl-1-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyran-4-carbonyloxy]-7-methyl-3-oxo-hexahydro-1h-cyclopenta[c]pyran-4-carboxylate)

3D SDF for NP0318899 (methyl (4s,4as,6s,7r,7as)-6-[(1s,4as,7s,7as)-7-methyl-1-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyran-4-carbonyloxy]-7-methyl-3-oxo-hexahydro-1h-cyclopenta[c]pyran-4-carboxylate)

3D-SDF for NP0318899 (methyl (4s,4as,6s,7r,7as)-6-[(1s,4as,7s,7as)-7-methyl-1-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyran-4-carbonyloxy]-7-methyl-3-oxo-hexahydro-1h-cyclopenta[c]pyran-4-carboxylate)

PDB for NP0318899 (methyl (4s,4as,6s,7r,7as)-6-[(1s,4as,7s,7as)-7-methyl-1-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyran-4-carbonyloxy]-7-methyl-3-oxo-hexahydro-1h-cyclopenta[c]pyran-4-carboxylate)

3D PDB for NP0318899 (methyl (4s,4as,6s,7r,7as)-6-[(1s,4as,7s,7as)-7-methyl-1-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyran-4-carbonyloxy]-7-methyl-3-oxo-hexahydro-1h-cyclopenta[c]pyran-4-carboxylate)

SMILES for NP0318899 (methyl (4s,4as,6s,7r,7as)-6-[(1s,4as,7s,7as)-7-methyl-1-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyran-4-carbonyloxy]-7-methyl-3-oxo-hexahydro-1h-cyclopenta[c]pyran-4-carboxylate)

INCHI for NP0318899 (methyl (4s,4as,6s,7r,7as)-6-[(1s,4as,7s,7as)-7-methyl-1-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyran-4-carbonyloxy]-7-methyl-3-oxo-hexahydro-1h-cyclopenta[c]pyran-4-carboxylate)

Structure for NP0318899 (methyl (4s,4as,6s,7r,7as)-6-[(1s,4as,7s,7as)-7-methyl-1-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyran-4-carbonyloxy]-7-methyl-3-oxo-hexahydro-1h-cyclopenta[c]pyran-4-carboxylate)

3D Structure for NP0318899 (methyl (4s,4as,6s,7r,7as)-6-[(1s,4as,7s,7as)-7-methyl-1-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyran-4-carbonyloxy]-7-methyl-3-oxo-hexahydro-1h-cyclopenta[c]pyran-4-carboxylate)