NP-MRD: Showing NP-Card for n-[(3r,4s,7s,8s,9r)-7-butyl-4,9-dimethyl-8-[(3-methylbutanoyl)oxy]-2,6-dioxo-1,5-dioxonan-3-yl]-2-hydroxy-3-[(hydroxymethylidene)amino]benzenecarboximidic acid (NP0314778)

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Record Information

Version

2.0

Created at

2022-09-11 13:04:07 UTC

Updated at

2022-09-11 13:04:07 UTC

NP-MRD ID

NP0314778

Secondary Accession Numbers

None

Natural Product Identification

Common Name

n-[(3r,4s,7s,8s,9r)-7-butyl-4,9-dimethyl-8-[(3-methylbutanoyl)oxy]-2,6-dioxo-1,5-dioxonan-3-yl]-2-hydroxy-3-[(hydroxymethylidene)amino]benzenecarboximidic acid

Description

Antimycin A3 belongs to the class of organic compounds known as acylaminobenzoic acid and derivatives. These are derivatives of amino benzoic acid derivatives where the amine group is N-acylated. n-[(3r,4s,7s,8s,9r)-7-butyl-4,9-dimethyl-8-[(3-methylbutanoyl)oxy]-2,6-dioxo-1,5-dioxonan-3-yl]-2-hydroxy-3-[(hydroxymethylidene)amino]benzenecarboximidic acid was first documented in 2004 (PMID: 16233742). Based on a literature review a small amount of articles have been published on Antimycin A3 (PMID: 24251103) (PMID: 17273826) (PMID: 17224645) (PMID: 15796162).

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652309112215042D          

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M  END

     RDKit          3D

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M  END


  Mrv1652309112215042D          

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  3  4  1  0  0  0  0
  5  4  1  6  0  0  0
  5  6  1  0  0  0  0
  6  7  2  0  0  0  0
  6  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  1  1  0  0  0
  9 11  1  0  0  0  0
 11 12  1  1  0  0  0
 12 13  2  0  0  0  0
 13 14  1  4  0  0  0
 13 15  1  0  0  0  0
 15 16  2  0  0  0  0
 16 17  1  0  0  0  0
 17 18  2  0  0  0  0
 18 19  1  0  0  0  0
 19 20  1  0  0  0  0
 20 21  2  0  0  0  0
 21 22  1  4  0  0  0
 19 23  2  0  0  0  0
 15 23  1  0  0  0  0
 23 24  1  0  0  0  0
 11 25  1  0  0  0  0
 25 26  2  0  0  0  0
 25 27  1  0  0  0  0
 27 28  1  0  0  0  0
 28 29  1  6  0  0  0
 28 30  1  0  0  0  0
  5 30  1  0  0  0  0
 30 31  1  1  0  0  0
 31 32  1  0  0  0  0
 32 33  2  0  0  0  0
 32 34  1  0  0  0  0
 34 35  1  0  0  0  0
 35 36  1  0  0  0  0
 35 37  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0314778

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CCCC[C@H]1[C@H](OC(=O)CC(C)C)[C@@H](C)OC(=O)[C@H](N=C(O)C2=CC=CC(N=CO)=C2O)[C@H](C)OC1=O

> <INCHI_IDENTIFIER>
InChI=1S/C26H36N2O9/c1-6-7-9-18-23(37-20(30)12-14(2)3)16(5)36-26(34)21(15(4)35-25(18)33)28-24(32)17-10-8-11-19(22(17)31)27-13-29/h8,10-11,13-16,18,21,23,31H,6-7,9,12H2,1-5H3,(H,27,29)(H,28,32)/t15-,16+,18-,21+,23+/m0/s1

> <INCHI_KEY>
PVEVXUMVNWSNIG-MUEDQRLYSA-N

> <FORMULA>
C26H36N2O9

> <MOLECULAR_WEIGHT>
520.579

> <EXACT_MASS>
520.242080747

> <JCHEM_ACCEPTOR_COUNT>
8

> <JCHEM_ATOM_COUNT>
73

> <JCHEM_AVERAGE_POLARIZABILITY>
55.3989563065201

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
3

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
N-[(3R,4S,7S,8S,9R)-7-butyl-4,9-dimethyl-8-[(3-methylbutanoyl)oxy]-2,6-dioxo-1,5-dioxonan-3-yl]-2-hydroxy-3-[(hydroxymethylidene)amino]benzene-1-carboximidic acid

> <JCHEM_LOGP>
6.258024519666666

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
2

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
7.3519718666634795

> <JCHEM_PKA_STRONGEST_ACIDIC>
3.287753685142542

> <JCHEM_PKA_STRONGEST_BASIC>
0.05460646203749675

> <JCHEM_POLAR_SURFACE_AREA>
164.30999999999997

> <JCHEM_REFRACTIVITY>
133.95199999999997

> <JCHEM_ROTATABLE_BOND_COUNT>
10

> <JCHEM_RULE_OF_FIVE>
0

> <JCHEM_TRADITIONAL_IUPAC>
N-[(3R,4S,7S,8S,9R)-7-butyl-4,9-dimethyl-8-[(3-methylbutanoyl)oxy]-2,6-dioxo-1,5-dioxonan-3-yl]-2-hydroxy-3-[(hydroxymethylidene)amino]benzenecarboximidic acid

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 11-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   11-SEP-22         0                                  
HETATM    1  C   UNK     0       3.281  -8.899   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       2.754  -7.452   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       1.238  -7.185   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       0.711  -5.738   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      -0.806  -5.470   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0      -1.576  -6.804   0.000  0.00  0.00           C+0
HETATM    7  O   UNK     0      -0.586  -7.984   0.000  0.00  0.00           O+0
HETATM    8  O   UNK     0      -3.023  -7.331   0.000  0.00  0.00           O+0
HETATM    9  C   UNK     0      -4.470  -6.804   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0      -5.460  -7.984   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0      -5.240  -5.470   0.000  0.00  0.00           C+0
HETATM   12  N   UNK     0      -6.757  -5.738   0.000  0.00  0.00           N+0
HETATM   13  C   UNK     0      -7.746  -4.558   0.000  0.00  0.00           C+0
HETATM   14  O   UNK     0      -7.220  -3.111   0.000  0.00  0.00           O+0
HETATM   15  C   UNK     0      -9.263  -4.825   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0      -9.790  -6.272   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0     -11.306  -6.540   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0     -12.296  -5.360   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0     -11.770  -3.913   0.000  0.00  0.00           C+0
HETATM   20  N   UNK     0     -12.759  -2.733   0.000  0.00  0.00           N+0
HETATM   21  C   UNK     0     -12.233  -1.286   0.000  0.00  0.00           C+0
HETATM   22  O   UNK     0     -13.223  -0.107   0.000  0.00  0.00           O+0
HETATM   23  C   UNK     0     -10.253  -3.646   0.000  0.00  0.00           C+0
HETATM   24  O   UNK     0      -9.726  -2.199   0.000  0.00  0.00           O+0
HETATM   25  C   UNK     0      -4.973  -3.954   0.000  0.00  0.00           C+0
HETATM   26  O   UNK     0      -6.306  -3.184   0.000  0.00  0.00           O+0
HETATM   27  O   UNK     0      -3.793  -2.964   0.000  0.00  0.00           O+0
HETATM   28  C   UNK     0      -2.253  -2.964   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0      -1.726  -1.517   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0      -1.073  -3.954   0.000  0.00  0.00           C+0
HETATM   31  O   UNK     0       0.261  -3.184   0.000  0.00  0.00           O+0
HETATM   32  C   UNK     0       1.594  -3.954   0.000  0.00  0.00           C+0
HETATM   33  O   UNK     0       1.594  -5.494   0.000  0.00  0.00           O+0
HETATM   34  C   UNK     0       2.928  -3.184   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0       4.262  -3.954   0.000  0.00  0.00           C+0
HETATM   36  C   UNK     0       5.595  -3.184   0.000  0.00  0.00           C+0
HETATM   37  C   UNK     0       4.262  -5.494   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4                                                       
CONECT    4    3    5                                                       
CONECT    5    4    6   30                                                  
CONECT    6    5    7    8                                                  
CONECT    7    6                                                            
CONECT    8    6    9                                                       
CONECT    9    8   10   11                                                  
CONECT   10    9                                                            
CONECT   11    9   12   25                                                  
CONECT   12   11   13                                                       
CONECT   13   12   14   15                                                  
CONECT   14   13                                                            
CONECT   15   13   16   23                                                  
CONECT   16   15   17                                                       
CONECT   17   16   18                                                       
CONECT   18   17   19                                                       
CONECT   19   18   20   23                                                  
CONECT   20   19   21                                                       
CONECT   21   20   22                                                       
CONECT   22   21                                                            
CONECT   23   19   15   24                                                  
CONECT   24   23                                                            
CONECT   25   11   26   27                                                  
CONECT   26   25                                                            
CONECT   27   25   28                                                       
CONECT   28   27   29   30                                                  
CONECT   29   28                                                            
CONECT   30   28    5   31                                                  
CONECT   31   30   32                                                       
CONECT   32   31   33   34                                                  
CONECT   33   32                                                            
CONECT   34   32   35                                                       
CONECT   35   34   36   37                                                  
CONECT   36   35                                                            
CONECT   37   35                                                            
MASTER        0    0    0    0    0    0    0    0   37    0   76    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₂₆H₃₆N₂O₉

Average Mass

520.5790 Da

Monoisotopic Mass

520.24208 Da

IUPAC Name

N-[(3R,4S,7S,8S,9R)-7-butyl-4,9-dimethyl-8-[(3-methylbutanoyl)oxy]-2,6-dioxo-1,5-dioxonan-3-yl]-2-hydroxy-3-[(hydroxymethylidene)amino]benzene-1-carboximidic acid

Traditional Name

N-[(3R,4S,7S,8S,9R)-7-butyl-4,9-dimethyl-8-[(3-methylbutanoyl)oxy]-2,6-dioxo-1,5-dioxonan-3-yl]-2-hydroxy-3-[(hydroxymethylidene)amino]benzenecarboximidic acid

CAS Registry Number

Not Available

SMILES

CCCC[C@H]1[C@H](OC(=O)CC(C)C)[C@@H](C)OC(=O)[C@H](N=C(O)C2=CC=CC(N=CO)=C2O)[C@H](C)OC1=O

InChI Identifier

InChI=1S/C26H36N2O9/c1-6-7-9-18-23(37-20(30)12-14(2)3)16(5)36-26(34)21(15(4)35-25(18)33)28-24(32)17-10-8-11-19(22(17)31)27-13-29/h8,10-11,13-16,18,21,23,31H,6-7,9,12H2,1-5H3,(H,27,29)(H,28,32)/t15-,16+,18-,21+,23+/m0/s1

InChI Key

PVEVXUMVNWSNIG-MUEDQRLYSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Not Available

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as acylaminobenzoic acid and derivatives. These are derivatives of amino benzoic acid derivatives where the amine group is N-acylated.

Kingdom

Organic compounds

Super Class

Benzenoids

Class

Benzene and substituted derivatives

Sub Class

Benzoic acids and derivatives

Direct Parent

Acylaminobenzoic acid and derivatives

Alternative Parents

Substituents

Alpha-amino acid ester
Acylaminobenzoic acid or derivatives
N-acyl-alpha amino acid or derivatives
Alpha-amino acid or derivatives
Salicylamide
Salicylic acid or derivatives
Benzamide
Anilide
Tricarboxylic acid or derivatives
Benzoyl
N-arylamide
1-hydroxy-4-unsubstituted benzenoid
Fatty acid ester
Phenol
Fatty acyl
Vinylogous acid
Carboxamide group
Carboxylic acid ester
Lactone
Secondary carboxylic acid amide
Oxacycle
Carboxylic acid derivative
Organoheterocyclic compound
Hydrocarbon derivative
Organic oxygen compound
Organic nitrogen compound
Carbonyl group
Organic oxide
Organonitrogen compound
Organooxygen compound
Organopnictogen compound
Aromatic heteromonocyclic compound

Molecular Framework

Aromatic heteromonocyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	6.26	ChemAxon
pKa (Strongest Acidic)	3.29	ChemAxon
pKa (Strongest Basic)	0.055	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	8	ChemAxon
Hydrogen Donor Count	3	ChemAxon
Polar Surface Area	164.31 Å²	ChemAxon
Rotatable Bond Count	10	ChemAxon
Refractivity	133.95 m³·mol⁻¹	ChemAxon
Polarizability	55.4 Å³	ChemAxon
Number of Rings	2	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

9527852

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

11352917

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

Taira Y, Okegawa Y, Sugimoto K, Abe M, Miyoshi H, Shikanai T: Antimycin A-like molecules inhibit cyclic electron transport around photosystem I in ruptured chloroplasts. FEBS Open Bio. 2013 Sep 30;3:406-10. doi: 10.1016/j.fob.2013.09.007. eCollection 2013. [PubMed:24251103 ]
Guichard SM, Hua ML, Kang P, Macpherson JS, Jodrell DI: Short hairpin RNAs targeting Bcl-xL modulate senescence and apoptosis following SN-38 and irinotecan exposure in a colon cancer model. Cancer Chemother Pharmacol. 2007 Oct;60(5):651-60. doi: 10.1007/s00280-006-0408-1. Epub 2007 Feb 2. [PubMed:17273826 ]
Cao X, Rodarte C, Zhang L, Morgan CD, Littlejohn J, Smythe WR: Bcl2/bcl-xL inhibitor engenders apoptosis and increases chemosensitivity in mesothelioma. Cancer Biol Ther. 2007 Feb;6(2):246-52. doi: 10.4161/cbt.6.2.3626. Epub 2007 Feb 26. [PubMed:17224645 ]
Fujita K, Kubo I: Potentiation of fungicidal activities of trans-anethole against Saccharomyces cerevisiae under hypoxic conditions. J Biosci Bioeng. 2004;98(6):490-2. doi: 10.1016/S1389-1723(05)00318-X. [PubMed:16233742 ]
Anderson KM, Rubenstein M, Alrefai WA, Dudeja P, Tsui P, Guinan P, Harris JE: Reactive oxygen species and redox-induced programmed cell death due to MK 886: cells ("soil") "trump" agent ("seed"). In Vivo. 2005 Jan-Feb;19(1):109-18. [PubMed:15796162 ]
LOTUS database [Link]

Showing NP-Card for n-[(3r,4s,7s,8s,9r)-7-butyl-4,9-dimethyl-8-[(3-methylbutanoyl)oxy]-2,6-dioxo-1,5-dioxonan-3-yl]-2-hydroxy-3-[(hydroxymethylidene)amino]benzenecarboximidic acid (NP0314778)

MOL for NP0314778 (n-[(3r,4s,7s,8s,9r)-7-butyl-4,9-dimethyl-8-[(3-methylbutanoyl)oxy]-2,6-dioxo-1,5-dioxonan-3-yl]-2-hydroxy-3-[(hydroxymethylidene)amino]benzenecarboximidic acid)

3D MOL for NP0314778 (n-[(3r,4s,7s,8s,9r)-7-butyl-4,9-dimethyl-8-[(3-methylbutanoyl)oxy]-2,6-dioxo-1,5-dioxonan-3-yl]-2-hydroxy-3-[(hydroxymethylidene)amino]benzenecarboximidic acid)

3D SDF for NP0314778 (n-[(3r,4s,7s,8s,9r)-7-butyl-4,9-dimethyl-8-[(3-methylbutanoyl)oxy]-2,6-dioxo-1,5-dioxonan-3-yl]-2-hydroxy-3-[(hydroxymethylidene)amino]benzenecarboximidic acid)

3D-SDF for NP0314778 (n-[(3r,4s,7s,8s,9r)-7-butyl-4,9-dimethyl-8-[(3-methylbutanoyl)oxy]-2,6-dioxo-1,5-dioxonan-3-yl]-2-hydroxy-3-[(hydroxymethylidene)amino]benzenecarboximidic acid)

PDB for NP0314778 (n-[(3r,4s,7s,8s,9r)-7-butyl-4,9-dimethyl-8-[(3-methylbutanoyl)oxy]-2,6-dioxo-1,5-dioxonan-3-yl]-2-hydroxy-3-[(hydroxymethylidene)amino]benzenecarboximidic acid)

3D PDB for NP0314778 (n-[(3r,4s,7s,8s,9r)-7-butyl-4,9-dimethyl-8-[(3-methylbutanoyl)oxy]-2,6-dioxo-1,5-dioxonan-3-yl]-2-hydroxy-3-[(hydroxymethylidene)amino]benzenecarboximidic acid)

SMILES for NP0314778 (n-[(3r,4s,7s,8s,9r)-7-butyl-4,9-dimethyl-8-[(3-methylbutanoyl)oxy]-2,6-dioxo-1,5-dioxonan-3-yl]-2-hydroxy-3-[(hydroxymethylidene)amino]benzenecarboximidic acid)

INCHI for NP0314778 (n-[(3r,4s,7s,8s,9r)-7-butyl-4,9-dimethyl-8-[(3-methylbutanoyl)oxy]-2,6-dioxo-1,5-dioxonan-3-yl]-2-hydroxy-3-[(hydroxymethylidene)amino]benzenecarboximidic acid)

Structure for NP0314778 (n-[(3r,4s,7s,8s,9r)-7-butyl-4,9-dimethyl-8-[(3-methylbutanoyl)oxy]-2,6-dioxo-1,5-dioxonan-3-yl]-2-hydroxy-3-[(hydroxymethylidene)amino]benzenecarboximidic acid)

3D Structure for NP0314778 (n-[(3r,4s,7s,8s,9r)-7-butyl-4,9-dimethyl-8-[(3-methylbutanoyl)oxy]-2,6-dioxo-1,5-dioxonan-3-yl]-2-hydroxy-3-[(hydroxymethylidene)amino]benzenecarboximidic acid)