NP-MRD: Showing NP-Card for 5,7-dihydroxy-2-{1-hydroxy-5-[(3-hydroxy-5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl)methyl]-6-methyl-2-oxo-1,5,8,8a-tetrahydronaphthalen-4a-yl}chromen-4-one (NP0314593)

Jump To Section:

Identification Spectra BioTaxonomy ChemoTaxonomy Physical properties Links References XML

Record Information

Version

2.0

Created at

2022-09-11 12:46:20 UTC

Updated at

2022-09-11 12:46:20 UTC

NP-MRD ID

NP0314593

Secondary Accession Numbers

None

Natural Product Identification

Common Name

5,7-dihydroxy-2-{1-hydroxy-5-[(3-hydroxy-5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl)methyl]-6-methyl-2-oxo-1,5,8,8a-tetrahydronaphthalen-4a-yl}chromen-4-one

Description

5,7-Dihydroxy-2-{1-hydroxy-5-[(3-hydroxy-5,5,8a-trimethyl-2-methylidene-decahydronaphthalen-1-yl)methyl]-6-methyl-2-oxo-1,2,4a,5,8,8a-hexahydronaphthalen-4a-yl}-4H-chromen-4-one belongs to the class of organic compounds known as diterpenoids. These are terpene compounds formed by four isoprene units. 5,7-dihydroxy-2-{1-hydroxy-5-[(3-hydroxy-5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl)methyl]-6-methyl-2-oxo-1,5,8,8a-tetrahydronaphthalen-4a-yl}chromen-4-one is found in Dichrostachys cinerea. 5,7-Dihydroxy-2-{1-hydroxy-5-[(3-hydroxy-5,5,8a-trimethyl-2-methylidene-decahydronaphthalen-1-yl)methyl]-6-methyl-2-oxo-1,2,4a,5,8,8a-hexahydronaphthalen-4a-yl}-4H-chromen-4-one is an extremely weak basic (essentially neutral) compound (based on its pKa).

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1533004161523532D          

 42 47  0  0  0  0            999 V2000
    0.3833   -3.8682    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.2971   -3.0477    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5099   -3.2192    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0619   -2.6061    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8070   -1.8215    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3590   -1.2084    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1660   -1.3800    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1041   -0.4238    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6561    0.1893    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2971   -0.2523    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.2549   -0.8654    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5520   -2.2631    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3590   -2.0916    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9110   -2.7047    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7180   -2.5331    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2029   -1.8657    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2700   -3.1462    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0770   -2.9747    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.0151   -3.9309    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2081   -4.1024    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9532   -4.8870    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7702   -5.0018    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9820   -5.7115    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1462   -5.0585    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5942   -4.4454    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8491   -3.6608    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6561   -3.4893    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1041   -2.8762    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.8250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.8250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868   -1.6500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -1.6500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  2  0  0  0  0
  3  4  1  0  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  6  7  1  0  0  0  0
  6  8  1  0  0  0  0
  8  9  2  0  0  0  0
  8 10  1  0  0  0  0
 10 11  2  0  0  0  0
 11 12  1  0  0  0  0
  5 12  1  0  0  0  0
 12 13  1  0  0  0  0
  2 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  2  0  0  0  0
 16 18  1  0  0  0  0
 18 19  1  0  0  0  0
 18 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  1  0  0  0  0
 22 24  1  0  0  0  0
 22 25  1  0  0  0  0
 25 26  1  0  0  0  0
 26 27  1  0  0  0  0
 27 28  1  0  0  0  0
 15 28  1  0  0  0  0
 21 28  1  0  0  0  0
 28 29  1  0  0  0  0
 12 30  1  0  0  0  0
 30 31  2  0  0  0  0
 31 32  1  0  0  0  0
 32 33  2  0  0  0  0
 32 34  1  0  0  0  0
 34 35  2  0  0  0  0
 35 36  1  0  0  0  0
 35 37  1  0  0  0  0
 37 38  2  0  0  0  0
 38 39  1  0  0  0  0
 38 40  1  0  0  0  0
 40 41  2  0  0  0  0
 34 41  1  0  0  0  0
 41 42  1  0  0  0  0
 30 42  1  0  0  0  0
M  END

     RDKit          3D

 84 89  0  0  0  0  0  0  0  0999 V2000
   -2.0162   -1.8516   -2.7619 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3114   -1.0939   -1.7189 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6553   -1.3129   -1.1217 C   0  0  1  0  0  0  0  0  0  0  0  0
   -3.6377   -2.3190   -0.1233 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3086   -0.0663   -0.6367 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4214    1.0997   -0.3727 C   0  0  1  0  0  0  0  0  0  0  0  0
   -4.0764    1.9781    0.6429 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.5043    1.4985    0.9858 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.2594    3.4147    0.2034 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3697    1.9919    1.9795 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7860    0.6718    2.3339 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7745    0.2196    1.3085 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9877    0.7612   -0.0656 C   0  0  2  0  0  0  0  0  0  0  0  0
   -1.2270    2.0885   -0.1205 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4027   -0.0901   -1.1799 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.0388   -0.3748   -1.0751 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6107   -1.4680   -0.3232 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.2320   -2.8539   -0.6865 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7271   -3.6950    0.0655 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7985   -3.4001   -1.7326 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7615   -2.6752   -2.5593 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6834   -1.8763   -1.6746 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.0062   -2.6392   -1.6651 C   0  0  1  0  0  0  0  0  0  0  0  0
    5.1145   -1.8355   -1.6200 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.9860   -3.7620   -0.7134 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.5598   -4.8653   -0.8907 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.2482   -3.5845    0.5250 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4367   -2.5920    0.7019 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1625   -1.5146   -0.3422 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.8135   -0.3219    0.1813 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0467   -0.5145    0.8352 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7511    0.5448    1.3646 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.8575    0.3865    1.9523 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.2219    1.8080    1.2422 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.9061    2.8959    1.7646 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.1129    2.6543    2.3965 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.3407    4.1300    1.6187 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1335    4.3055    0.9777 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5806    5.5893    0.8454 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.4537    3.2240    0.4586 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.0161    1.9625    0.5992 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4302    0.9006    0.1343 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6798   -2.6036   -3.1763 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0510   -1.7463   -3.2752 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3607   -1.7802   -1.8786 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3631   -2.1183    0.5041 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1038    0.2478   -1.3771 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9120   -0.3878    0.2653 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3809    1.7000   -1.3318 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.4880    0.7581    1.8081 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.0849    1.2334    0.1060 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.0677    2.3743    1.4392 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0783    3.5524   -0.9019 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3261    3.7454    0.3186 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6954    4.1432    0.8231 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1105    2.2345    2.8037 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6208    2.7780    2.0515 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5470   -0.1117    2.5418 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2733    0.8049    3.3307 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7728    0.4773    1.7270 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8129   -0.8948    1.3474 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8940    2.9643   -0.1730 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4717    2.1544    0.6738 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6404    2.1661   -1.0907 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4174    0.7148   -2.0429 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.4310    0.5857   -0.5691 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.5726   -0.2949   -2.0651 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.4119   -1.3643    0.7763 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2291   -4.5819    0.5277 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1870   -3.1297    0.8893 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5679   -4.0488   -0.5907 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.5630   -4.4427   -2.0301 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.3862   -3.4271   -3.1611 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.2942   -2.0548   -3.3660 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.9539   -0.9157   -2.2351 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.0632   -3.1316   -2.6898 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.8730   -2.3226   -2.0036 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.3576   -4.2950    1.3583 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.9032   -2.4767    1.6255 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.4770   -1.4999    0.9597 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.7028    3.3386    2.8129 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.8491    4.9938    2.0143 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.9529    5.9496    1.5744 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.5070    3.2925   -0.0540 H   0  0  0  0  0  0  0  0  0  0  0  0
 19 18  1  0
 18 20  2  0
 20 21  1  0
 21 22  1  0
 22 23  1  0
 23 24  1  0
 23 25  1  0
 25 26  2  0
 25 27  1  0
 27 28  2  0
 28 29  1  0
 29 17  1  0
 17 16  1  0
 16 15  1  0
 15  2  1  0
  2  1  2  3
  2  3  1  0
  3  4  1  0
  3  5  1  0
  5  6  1  0
  6  7  1  0
  7  8  1  0
  7  9  1  0
  7 10  1  0
 10 11  1  0
 11 12  1  0
 12 13  1  0
 13 14  1  1
 29 30  1  1
 30 31  2  0
 31 32  1  0
 32 33  2  0
 32 34  1  0
 34 35  2  0
 35 36  1  0
 35 37  1  0
 37 38  2  0
 38 39  1  0
 38 40  1  0
 40 41  2  0
 41 42  1  0
 17 18  1  0
 13 15  1  0
 42 30  1  0
 29 22  1  0
 13  6  1  0
 41 34  1  0
 19 69  1  0
 19 70  1  0
 19 71  1  0
 20 72  1  0
 21 73  1  0
 21 74  1  0
 22 75  1  6
 23 76  1  6
 24 77  1  0
 27 78  1  0
 28 79  1  0
 17 68  1  1
 16 66  1  0
 16 67  1  0
 15 65  1  6
  1 43  1  0
  1 44  1  0
  3 45  1  6
  4 46  1  0
  5 47  1  0
  5 48  1  0
  6 49  1  6
  8 50  1  0
  8 51  1  0
  8 52  1  0
  9 53  1  0
  9 54  1  0
  9 55  1  0
 10 56  1  0
 10 57  1  0
 11 58  1  0
 11 59  1  0
 12 60  1  0
 12 61  1  0
 14 62  1  0
 14 63  1  0
 14 64  1  0
 31 80  1  0
 36 81  1  0
 37 82  1  0
 39 83  1  0
 40 84  1  0
M  END


  Mrv1533004161523532D          

 42 47  0  0  0  0            999 V2000
    0.3833   -3.8682    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.2971   -3.0477    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5099   -3.2192    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0619   -2.6061    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8070   -1.8215    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3590   -1.2084    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1660   -1.3800    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1041   -0.4238    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6561    0.1893    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2971   -0.2523    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.2549   -0.8654    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5520   -2.2631    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3590   -2.0916    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9110   -2.7047    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7180   -2.5331    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2029   -1.8657    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2700   -3.1462    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0770   -2.9747    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.0151   -3.9309    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2081   -4.1024    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9532   -4.8870    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7702   -5.0018    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9820   -5.7115    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1462   -5.0585    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5942   -4.4454    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8491   -3.6608    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6561   -3.4893    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1041   -2.8762    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.8250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.8250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868   -1.6500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -1.6500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  2  0  0  0  0
  3  4  1  0  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  6  7  1  0  0  0  0
  6  8  1  0  0  0  0
  8  9  2  0  0  0  0
  8 10  1  0  0  0  0
 10 11  2  0  0  0  0
 11 12  1  0  0  0  0
  5 12  1  0  0  0  0
 12 13  1  0  0  0  0
  2 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  2  0  0  0  0
 16 18  1  0  0  0  0
 18 19  1  0  0  0  0
 18 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  1  0  0  0  0
 22 24  1  0  0  0  0
 22 25  1  0  0  0  0
 25 26  1  0  0  0  0
 26 27  1  0  0  0  0
 27 28  1  0  0  0  0
 15 28  1  0  0  0  0
 21 28  1  0  0  0  0
 28 29  1  0  0  0  0
 12 30  1  0  0  0  0
 30 31  2  0  0  0  0
 31 32  1  0  0  0  0
 32 33  2  0  0  0  0
 32 34  1  0  0  0  0
 34 35  2  0  0  0  0
 35 36  1  0  0  0  0
 35 37  1  0  0  0  0
 37 38  2  0  0  0  0
 38 39  1  0  0  0  0
 38 40  1  0  0  0  0
 40 41  2  0  0  0  0
 34 41  1  0  0  0  0
 41 42  1  0  0  0  0
 30 42  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0314593

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CC1=CCC2C(O)C(=O)C=CC2(C1CC1C(=C)C(O)CC2C(C)(C)CCCC12C)C1=CC(=O)C2=C(O)C=C(O)C=C2O1

> <INCHI_IDENTIFIER>
InChI=1S/C35H42O7/c1-18-7-8-21-32(41)24(37)9-12-35(21,30-17-27(40)31-26(39)13-20(36)14-28(31)42-30)22(18)15-23-19(2)25(38)16-29-33(3,4)10-6-11-34(23,29)5/h7,9,12-14,17,21-23,25,29,32,36,38-39,41H,2,6,8,10-11,15-16H2,1,3-5H3

> <INCHI_KEY>
NNBNXABSIDFNHX-UHFFFAOYSA-N

> <FORMULA>
C35H42O7

> <MOLECULAR_WEIGHT>
574.714

> <EXACT_MASS>
574.293053692

> <JCHEM_ACCEPTOR_COUNT>
7

> <JCHEM_ATOM_COUNT>
84

> <JCHEM_AVERAGE_POLARIZABILITY>
62.58472302782548

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
4

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
5,7-dihydroxy-2-{1-hydroxy-5-[(3-hydroxy-5,5,8a-trimethyl-2-methylidene-decahydronaphthalen-1-yl)methyl]-6-methyl-2-oxo-1,2,4a,5,8,8a-hexahydronaphthalen-4a-yl}-4H-chromen-4-one

> <ALOGPS_LOGP>
5.28

> <JCHEM_LOGP>
5.597543291666668

> <ALOGPS_LOGS>
-4.73

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
6

> <JCHEM_PHYSIOLOGICAL_CHARGE>
-1

> <JCHEM_PKA>
8.192391490724088

> <JCHEM_PKA_STRONGEST_ACIDIC>
6.589614557654004

> <JCHEM_PKA_STRONGEST_BASIC>
-1.2730441704687334

> <JCHEM_POLAR_SURFACE_AREA>
124.29

> <JCHEM_REFRACTIVITY>
163.09779999999998

> <JCHEM_ROTATABLE_BOND_COUNT>
3

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
1.06e-02 g/l

> <JCHEM_TRADITIONAL_IUPAC>
5,7-dihydroxy-2-{1-hydroxy-5-[(3-hydroxy-5,5,8a-trimethyl-2-methylidene-hexahydro-1H-naphthalen-1-yl)methyl]-6-methyl-2-oxo-1,5,8,8a-tetrahydronaphthalen-4a-yl}chromen-4-one

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 16-APR-15   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   16-APR-15         0                                  
HETATM    1  C   UNK     0       0.716  -7.221   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       0.555  -5.689   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      -0.952  -6.009   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      -1.982  -4.865   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      -1.506  -3.400   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0      -2.537  -2.256   0.000  0.00  0.00           C+0
HETATM    7  O   UNK     0      -4.043  -2.576   0.000  0.00  0.00           O+0
HETATM    8  C   UNK     0      -2.061  -0.791   0.000  0.00  0.00           C+0
HETATM    9  O   UNK     0      -3.091   0.353   0.000  0.00  0.00           O+0
HETATM   10  C   UNK     0      -0.555  -0.471   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       0.476  -1.615   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       0.000  -3.080   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       1.030  -4.224   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       2.537  -3.904   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       3.567  -5.049   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       5.074  -4.729   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       5.979  -3.483   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       6.104  -5.873   0.000  0.00  0.00           C+0
HETATM   19  O   UNK     0       7.610  -5.553   0.000  0.00  0.00           O+0
HETATM   20  C   UNK     0       5.628  -7.338   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0       4.122  -7.658   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0       3.646  -9.122   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0       5.171  -9.337   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0       3.700 -10.661   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0       2.140  -9.443   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0       1.109  -8.298   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0       1.585  -6.834   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0       3.091  -6.513   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0       2.061  -5.369   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0       1.334  -2.310   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0       1.334  -0.770   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0       2.667   0.000   0.000  0.00  0.00           C+0
HETATM   33  O   UNK     0       2.667   1.540   0.000  0.00  0.00           O+0
HETATM   34  C   UNK     0       4.001  -0.770   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0       5.335   0.000   0.000  0.00  0.00           C+0
HETATM   36  O   UNK     0       5.335   1.540   0.000  0.00  0.00           O+0
HETATM   37  C   UNK     0       6.668  -0.770   0.000  0.00  0.00           C+0
HETATM   38  C   UNK     0       6.668  -2.310   0.000  0.00  0.00           C+0
HETATM   39  O   UNK     0       8.002  -3.080   0.000  0.00  0.00           O+0
HETATM   40  C   UNK     0       5.335  -3.080   0.000  0.00  0.00           C+0
HETATM   41  C   UNK     0       4.001  -2.310   0.000  0.00  0.00           C+0
HETATM   42  O   UNK     0       2.667  -3.080   0.000  0.00  0.00           O+0
CONECT    1    2                                                            
CONECT    2    1    3   13                                                  
CONECT    3    2    4                                                       
CONECT    4    3    5                                                       
CONECT    5    4    6   12                                                  
CONECT    6    5    7    8                                                  
CONECT    7    6                                                            
CONECT    8    6    9   10                                                  
CONECT    9    8                                                            
CONECT   10    8   11                                                       
CONECT   11   10   12                                                       
CONECT   12   11    5   13   30                                             
CONECT   13   12    2   14                                                  
CONECT   14   13   15                                                       
CONECT   15   14   16   28                                                  
CONECT   16   15   17   18                                                  
CONECT   17   16                                                            
CONECT   18   16   19   20                                                  
CONECT   19   18                                                            
CONECT   20   18   21                                                       
CONECT   21   20   22   28                                                  
CONECT   22   21   23   24   25                                             
CONECT   23   22                                                            
CONECT   24   22                                                            
CONECT   25   22   26                                                       
CONECT   26   25   27                                                       
CONECT   27   26   28                                                       
CONECT   28   27   15   21   29                                             
CONECT   29   28                                                            
CONECT   30   12   31   42                                                  
CONECT   31   30   32                                                       
CONECT   32   31   33   34                                                  
CONECT   33   32                                                            
CONECT   34   32   35   41                                                  
CONECT   35   34   36   37                                                  
CONECT   36   35                                                            
CONECT   37   35   38                                                       
CONECT   38   37   39   40                                                  
CONECT   39   38                                                            
CONECT   40   38   41                                                       
CONECT   41   40   34   42                                                  
CONECT   42   41   30                                                       
MASTER        0    0    0    0    0    0    0    0   42    0   94    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₃₅H₄₂O₇

Average Mass

574.7140 Da

Monoisotopic Mass

574.29305 Da

IUPAC Name

5,7-dihydroxy-2-{1-hydroxy-5-[(3-hydroxy-5,5,8a-trimethyl-2-methylidene-decahydronaphthalen-1-yl)methyl]-6-methyl-2-oxo-1,2,4a,5,8,8a-hexahydronaphthalen-4a-yl}-4H-chromen-4-one

Traditional Name

5,7-dihydroxy-2-{1-hydroxy-5-[(3-hydroxy-5,5,8a-trimethyl-2-methylidene-hexahydro-1H-naphthalen-1-yl)methyl]-6-methyl-2-oxo-1,5,8,8a-tetrahydronaphthalen-4a-yl}chromen-4-one

CAS Registry Number

Not Available

SMILES

CC1=CCC2C(O)C(=O)C=CC2(C1CC1C(=C)C(O)CC2C(C)(C)CCCC12C)C1=CC(=O)C2=C(O)C=C(O)C=C2O1

InChI Identifier

InChI=1S/C35H42O7/c1-18-7-8-21-32(41)24(37)9-12-35(21,30-17-27(40)31-26(39)13-20(36)14-28(31)42-30)22(18)15-23-19(2)25(38)16-29-33(3,4)10-6-11-34(23,29)5/h7,9,12-14,17,21-23,25,29,32,36,38-39,41H,2,6,8,10-11,15-16H2,1,3-5H3

InChI Key

NNBNXABSIDFNHX-UHFFFAOYSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Dichrostachys cinerea	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as diterpenoids. These are terpene compounds formed by four isoprene units.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Prenol lipids

Sub Class

Diterpenoids

Direct Parent

Diterpenoids

Alternative Parents

Substituents

Labdane diterpenoid
Diterpenoid
Chromone
Benzopyran
1-benzopyran
Cyclohexenone
1-hydroxy-4-unsubstituted benzenoid
1-hydroxy-2-unsubstituted benzenoid
Pyranone
Pyran
Benzenoid
Cyclic alcohol
Heteroaromatic compound
Vinylogous acid
Cyclic ketone
Secondary alcohol
Ketone
Organoheterocyclic compound
Oxacycle
Organic oxide
Organooxygen compound
Organic oxygen compound
Carbonyl group
Alcohol
Hydrocarbon derivative
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	5.28	ALOGPS
logP	5.6	ChemAxon
logS	-4.7	ALOGPS
pKa (Strongest Acidic)	6.59	ChemAxon
pKa (Strongest Basic)	-1.3	ChemAxon
Physiological Charge	-1	ChemAxon
Hydrogen Acceptor Count	7	ChemAxon
Hydrogen Donor Count	4	ChemAxon
Polar Surface Area	124.29 Å²	ChemAxon
Rotatable Bond Count	3	ChemAxon
Refractivity	163.1 m³·mol⁻¹	ChemAxon
Polarizability	62.58 Å³	ChemAxon
Number of Rings	6	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

75068883

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for 5,7-dihydroxy-2-{1-hydroxy-5-[(3-hydroxy-5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl)methyl]-6-methyl-2-oxo-1,5,8,8a-tetrahydronaphthalen-4a-yl}chromen-4-one (NP0314593)

MOL for NP0314593 (5,7-dihydroxy-2-{1-hydroxy-5-[(3-hydroxy-5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl)methyl]-6-methyl-2-oxo-1,5,8,8a-tetrahydronaphthalen-4a-yl}chromen-4-one)

3D MOL for NP0314593 (5,7-dihydroxy-2-{1-hydroxy-5-[(3-hydroxy-5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl)methyl]-6-methyl-2-oxo-1,5,8,8a-tetrahydronaphthalen-4a-yl}chromen-4-one)

3D SDF for NP0314593 (5,7-dihydroxy-2-{1-hydroxy-5-[(3-hydroxy-5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl)methyl]-6-methyl-2-oxo-1,5,8,8a-tetrahydronaphthalen-4a-yl}chromen-4-one)

3D-SDF for NP0314593 (5,7-dihydroxy-2-{1-hydroxy-5-[(3-hydroxy-5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl)methyl]-6-methyl-2-oxo-1,5,8,8a-tetrahydronaphthalen-4a-yl}chromen-4-one)

PDB for NP0314593 (5,7-dihydroxy-2-{1-hydroxy-5-[(3-hydroxy-5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl)methyl]-6-methyl-2-oxo-1,5,8,8a-tetrahydronaphthalen-4a-yl}chromen-4-one)

3D PDB for NP0314593 (5,7-dihydroxy-2-{1-hydroxy-5-[(3-hydroxy-5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl)methyl]-6-methyl-2-oxo-1,5,8,8a-tetrahydronaphthalen-4a-yl}chromen-4-one)

SMILES for NP0314593 (5,7-dihydroxy-2-{1-hydroxy-5-[(3-hydroxy-5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl)methyl]-6-methyl-2-oxo-1,5,8,8a-tetrahydronaphthalen-4a-yl}chromen-4-one)

INCHI for NP0314593 (5,7-dihydroxy-2-{1-hydroxy-5-[(3-hydroxy-5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl)methyl]-6-methyl-2-oxo-1,5,8,8a-tetrahydronaphthalen-4a-yl}chromen-4-one)

Structure for NP0314593 (5,7-dihydroxy-2-{1-hydroxy-5-[(3-hydroxy-5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl)methyl]-6-methyl-2-oxo-1,5,8,8a-tetrahydronaphthalen-4a-yl}chromen-4-one)

3D Structure for NP0314593 (5,7-dihydroxy-2-{1-hydroxy-5-[(3-hydroxy-5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl)methyl]-6-methyl-2-oxo-1,5,8,8a-tetrahydronaphthalen-4a-yl}chromen-4-one)