NP-MRD: Showing NP-Card for 1-(2,3-dihydroxy-6-methylheptan-2-yl)-3a,8-dihydroxy-9a,11a-dimethyl-7-[(3,4,5-trihydroxyoxan-2-yl)oxy]-1h,2h,3h,5ah,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-5-one (NP0314576)

Jump To Section:

Identification Spectra BioTaxonomy ChemoTaxonomy Physical properties Links References XML

Record Information

Version

2.0

Created at

2022-09-11 12:44:45 UTC

Updated at

2022-09-11 12:44:45 UTC

NP-MRD ID

NP0314576

Secondary Accession Numbers

None

Natural Product Identification

Common Name

1-(2,3-dihydroxy-6-methylheptan-2-yl)-3a,8-dihydroxy-9a,11a-dimethyl-7-[(3,4,5-trihydroxyoxan-2-yl)oxy]-1h,2h,3h,5ah,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-5-one

Description

14-(2,3-Dihydroxy-6-methylheptan-2-yl)-4,11-dihydroxy-2,15-dimethyl-5-[(3,4,5-trihydroxyoxan-2-yl)oxy]tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]Heptadec-9-en-8-one belongs to the class of organic compounds known as steroidal glycosides. These are sterol lipids containing a carbohydrate moiety glycosidically linked to the steroid skeleton. 1-(2,3-dihydroxy-6-methylheptan-2-yl)-3a,8-dihydroxy-9a,11a-dimethyl-7-[(3,4,5-trihydroxyoxan-2-yl)oxy]-1h,2h,3h,5ah,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-5-one is found in Limnanthes douglasii. 14-(2,3-Dihydroxy-6-methylheptan-2-yl)-4,11-dihydroxy-2,15-dimethyl-5-[(3,4,5-trihydroxyoxan-2-yl)oxy]tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]Heptadec-9-en-8-one is an extremely weak basic (essentially neutral) compound (based on its pKa).

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1533004161515362D          

 42 46  0  0  0  0            999 V2000
   -0.5916   -4.8691    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0853   -4.2178    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3962   -3.4536    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7320   -4.3306    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2383   -3.6793    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0556   -3.7922    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3665   -4.5563    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.5619   -3.1408    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2132   -3.6472    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9106   -2.6345    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.0683   -2.4895    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8390   -1.6970    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5218   -1.2340    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.1731   -1.7404    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3708   -0.9394    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.9853   -1.5952    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2655   -0.8192    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0777   -0.6740    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.3580    0.1019    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.6095   -1.3047    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.4216   -1.1595    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.9534   -1.7902    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.7655   -1.6450    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    9.0458   -0.8691    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.5140   -0.2384    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.7943    0.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.6064    0.6828    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.8867    1.4587    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   10.1383    0.0521    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.9504    0.1973    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    9.8580   -0.7239    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.3898   -1.3546    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.6731   -2.5662    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.2049   -3.1969    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.8610   -2.7114    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.3292   -2.0807    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0489   -2.8566    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.5171   -2.2259    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2368   -3.0018    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4247   -3.1470    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.8928   -2.5163    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5330   -3.2587    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  2  4  1  0  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  6  7  1  0  0  0  0
  6  8  1  0  0  0  0
  8  9  1  0  0  0  0
  8 10  1  0  0  0  0
  8 11  1  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 14 16  1  0  0  0  0
 16 17  2  0  0  0  0
 17 18  1  0  0  0  0
 18 19  2  0  0  0  0
 18 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  1  0  0  0  0
 23 24  1  0  0  0  0
 24 25  1  0  0  0  0
 25 26  1  0  0  0  0
 26 27  1  0  0  0  0
 27 28  1  0  0  0  0
 27 29  1  0  0  0  0
 29 30  1  0  0  0  0
 29 31  1  0  0  0  0
 24 31  1  0  0  0  0
 31 32  1  0  0  0  0
 22 33  1  0  0  0  0
 33 34  1  0  0  0  0
 33 35  1  0  0  0  0
 35 36  1  0  0  0  0
 20 36  1  0  0  0  0
 36 37  1  0  0  0  0
 36 38  1  0  0  0  0
 16 38  1  0  0  0  0
 38 39  1  0  0  0  0
 39 40  1  0  0  0  0
 40 41  1  0  0  0  0
 11 41  1  0  0  0  0
 14 41  1  0  0  0  0
 41 42  1  0  0  0  0
M  END

     RDKit          3D

 94 98  0  0  0  0  0  0  0  0999 V2000
   -7.9910    1.6518   -1.7048 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.9417    2.6379   -1.3901 C   0  0  0  0  0  0  0  0  0  0  0  0
   -7.5042    3.7096   -0.4200 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.5767    2.2540   -1.0121 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.2759    1.4579    0.1762 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.6327    0.0627    0.3618 C   0  0  1  0  0  0  0  0  0  0  0  0
   -6.9792   -0.1659    0.2258 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.8224   -1.0398   -0.1800 C   0  0  2  0  0  0  0  0  0  0  0  0
   -5.3115   -1.2977   -1.6013 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1970   -2.1979    0.5808 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3758   -1.0046   -0.2176 C   0  0  2  0  0  0  0  0  0  0  0  0
   -2.9319   -2.3615   -0.8269 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4205   -3.1345    0.3744 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6955   -2.0877    1.1576 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.7225   -2.4658    2.5037 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2645   -1.9361    0.8067 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3426   -2.5993   -0.1648 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7476   -2.4101   -0.4652 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3598   -3.2190   -1.1730 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.4286   -1.2295    0.0943 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.8791   -1.2957   -0.0308 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3643    0.3621    0.2044 C   0  0  2  0  0  0  0  0  0  0  0  0
    5.6482    0.0618    0.3557 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.5036    0.6394   -0.5748 C   0  0  2  0  0  0  0  0  0  0  0  0
    7.2995   -0.2772   -1.2648 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.7222    0.4411   -2.4130 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.8107    1.3584   -1.9479 C   0  0  1  0  0  0  0  0  0  0  0  0
    9.2222    2.1643   -3.0111 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.4098    2.2348   -0.8054 C   0  0  2  0  0  0  0  0  0  0  0  0
    9.5696    2.5323   -0.0832 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.4372    1.5751    0.1543 C   0  0  2  0  0  0  0  0  0  0  0  0
    8.1863    0.8244    1.0562 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.9982    0.3146    1.9061 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.6998    1.4117    2.2848 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.5211    0.4142    1.8686 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9312   -0.9255    1.4937 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.5414   -1.9426    2.4705 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4779   -0.9597    1.6518 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.2899    0.3208    1.5395 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4303    0.2517    0.5823 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4940   -0.7854    0.9221 C   0  0  1  0  0  0  0  0  0  0  0  0
   -3.0886   -0.4404    2.2365 C   0  0  0  0  0  0  0  0  0  0  0  0
   -7.6679    0.7647   -2.2241 H   0  0  0  0  0  0  0  0  0  0  0  0
   -8.6579    2.1704   -2.5048 H   0  0  0  0  0  0  0  0  0  0  0  0
   -8.7401    1.5021   -0.8897 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.8095    3.2679   -2.3439 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.7984    4.5146   -0.2355 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.8208    3.1322    0.4736 H   0  0  0  0  0  0  0  0  0  0  0  0
   -8.4232    4.1389   -0.8683 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1336    1.7464   -1.9418 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9751    3.2363   -1.0089 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1505    1.6407    0.3638 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.6827    2.0140    1.1170 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.6120   -0.1118    1.5787 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.3245   -0.9512    0.7093 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3851   -1.3641   -2.2487 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.7717   -2.2947   -1.7136 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.8948   -0.4819   -2.0186 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.7596   -2.7901    0.0504 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0883   -0.2782   -1.0451 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1684   -2.2524   -1.5824 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7773   -2.9527   -1.1956 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8664   -4.0341    0.1384 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3123   -3.4539    0.9943 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8420   -3.4417    2.5725 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2109   -3.2954   -0.7486 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.0633   -0.3524   -0.5236 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.4936   -1.8139    0.6505 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.2186   -1.3418   -1.0591 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.4903    0.6227    0.0193 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.9330    1.2846   -1.3004 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.1074   -0.2380   -3.1742 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.8588    1.0015   -2.8424 H   0  0  0  0  0  0  0  0  0  0  0  0
    9.6511    0.6959   -1.6034 H   0  0  0  0  0  0  0  0  0  0  0  0
    9.5970    1.5524   -3.6964 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.9845    3.1942   -1.1540 H   0  0  0  0  0  0  0  0  0  0  0  0
   10.3750    2.0796   -0.4268 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.8927    2.3618    0.7077 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.7431    0.2060    0.4925 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.3486   -0.6475    2.1802 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.1286    2.1436    2.6562 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.2927    1.2046    1.0860 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.0828    0.7750    2.8140 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.7054   -2.6068    2.8464 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.2504   -2.6216    2.0016 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.9028   -1.4305    3.3662 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.2749   -1.3338    2.7168 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6851    0.6689    2.5307 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.3262    1.1936    1.1939 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0158   -0.0274   -0.4180 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8183    1.2666    0.4594 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7844   -1.2302    2.6002 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4536    0.5762    2.3500 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2454   -0.5141    2.9960 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  2  4  1  0
  4  5  1  0
  5  6  1  0
  6  7  1  0
  6  8  1  0
  8  9  1  0
  8 10  1  1
  8 11  1  0
 11 12  1  0
 12 13  1  0
 13 14  1  0
 14 15  1  1
 14 16  1  0
 16 17  2  0
 17 18  1  0
 18 19  2  0
 18 20  1  0
 20 21  1  0
 21 22  1  0
 22 23  1  0
 23 24  1  0
 24 25  1  0
 25 26  1  0
 26 27  1  0
 27 28  1  0
 27 29  1  0
 29 30  1  0
 29 31  1  0
 31 32  1  0
 22 33  1  0
 33 34  1  0
 33 35  1  0
 35 36  1  0
 36 37  1  1
 36 38  1  0
 38 39  1  0
 39 40  1  0
 40 41  1  0
 41 42  1  1
 41 11  1  0
 41 14  1  0
 38 16  1  0
 36 20  1  0
 31 24  1  0
  1 43  1  0
  1 44  1  0
  1 45  1  0
  2 46  1  0
  3 47  1  0
  3 48  1  0
  3 49  1  0
  4 50  1  0
  4 51  1  0
  5 52  1  0
  5 53  1  0
  6 54  1  1
  7 55  1  0
  9 56  1  0
  9 57  1  0
  9 58  1  0
 10 59  1  0
 11 60  1  6
 12 61  1  0
 12 62  1  0
 13 63  1  0
 13 64  1  0
 15 65  1  0
 17 66  1  0
 20 67  1  6
 21 68  1  0
 21 69  1  0
 22 70  1  6
 24 71  1  6
 26 72  1  0
 26 73  1  0
 27 74  1  1
 28 75  1  0
 29 76  1  6
 30 77  1  0
 31 78  1  1
 32 79  1  0
 33 80  1  1
 34 81  1  0
 35 82  1  0
 35 83  1  0
 37 84  1  0
 37 85  1  0
 37 86  1  0
 38 87  1  1
 39 88  1  0
 39 89  1  0
 40 90  1  0
 40 91  1  0
 42 92  1  0
 42 93  1  0
 42 94  1  0
M  END


  Mrv1533004161515362D          

 42 46  0  0  0  0            999 V2000
   -0.5916   -4.8691    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0853   -4.2178    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3962   -3.4536    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7320   -4.3306    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2383   -3.6793    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0556   -3.7922    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3665   -4.5563    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.5619   -3.1408    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2132   -3.6472    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9106   -2.6345    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.0683   -2.4895    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8390   -1.6970    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5218   -1.2340    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.1731   -1.7404    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3708   -0.9394    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.9853   -1.5952    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2655   -0.8192    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0777   -0.6740    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.3580    0.1019    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.6095   -1.3047    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.4216   -1.1595    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.9534   -1.7902    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.7655   -1.6450    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    9.0458   -0.8691    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.5140   -0.2384    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.7943    0.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.6064    0.6828    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.8867    1.4587    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   10.1383    0.0521    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.9504    0.1973    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    9.8580   -0.7239    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.3898   -1.3546    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.6731   -2.5662    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.2049   -3.1969    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.8610   -2.7114    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.3292   -2.0807    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0489   -2.8566    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.5171   -2.2259    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2368   -3.0018    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4247   -3.1470    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.8928   -2.5163    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5330   -3.2587    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  2  4  1  0  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  6  7  1  0  0  0  0
  6  8  1  0  0  0  0
  8  9  1  0  0  0  0
  8 10  1  0  0  0  0
  8 11  1  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 14 16  1  0  0  0  0
 16 17  2  0  0  0  0
 17 18  1  0  0  0  0
 18 19  2  0  0  0  0
 18 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  1  0  0  0  0
 23 24  1  0  0  0  0
 24 25  1  0  0  0  0
 25 26  1  0  0  0  0
 26 27  1  0  0  0  0
 27 28  1  0  0  0  0
 27 29  1  0  0  0  0
 29 30  1  0  0  0  0
 29 31  1  0  0  0  0
 24 31  1  0  0  0  0
 31 32  1  0  0  0  0
 22 33  1  0  0  0  0
 33 34  1  0  0  0  0
 33 35  1  0  0  0  0
 35 36  1  0  0  0  0
 20 36  1  0  0  0  0
 36 37  1  0  0  0  0
 36 38  1  0  0  0  0
 16 38  1  0  0  0  0
 38 39  1  0  0  0  0
 39 40  1  0  0  0  0
 40 41  1  0  0  0  0
 11 41  1  0  0  0  0
 14 41  1  0  0  0  0
 41 42  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0314576

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CC(C)CCC(O)C(C)(O)C1CCC2(O)C3=CC(=O)C4CC(OC5OCC(O)C(O)C5O)C(O)CC4(C)C3CCC12C

> <INCHI_IDENTIFIER>
InChI=1S/C32H52O10/c1-16(2)6-7-25(36)31(5,39)24-9-11-32(40)18-12-20(33)19-13-23(42-28-27(38)26(37)22(35)15-41-28)21(34)14-29(19,3)17(18)8-10-30(24,32)4/h12,16-17,19,21-28,34-40H,6-11,13-15H2,1-5H3

> <INCHI_KEY>
YVYGCJBVFDRKJN-UHFFFAOYSA-N

> <FORMULA>
C32H52O10

> <MOLECULAR_WEIGHT>
596.758

> <EXACT_MASS>
596.356047874

> <JCHEM_ACCEPTOR_COUNT>
10

> <JCHEM_ATOM_COUNT>
94

> <JCHEM_AVERAGE_POLARIZABILITY>
65.48937388487141

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
7

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
14-(2,3-dihydroxy-6-methylheptan-2-yl)-4,11-dihydroxy-2,15-dimethyl-5-[(3,4,5-trihydroxyoxan-2-yl)oxy]tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-9-en-8-one

> <ALOGPS_LOGP>
0.73

> <JCHEM_LOGP>
0.9404761859999982

> <ALOGPS_LOGS>
-3.05

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
5

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
13.085208652520507

> <JCHEM_PKA_STRONGEST_ACIDIC>
12.210589728927513

> <JCHEM_PKA_STRONGEST_BASIC>
-3.1601278735230744

> <JCHEM_POLAR_SURFACE_AREA>
177.14

> <JCHEM_REFRACTIVITY>
153.49050000000003

> <JCHEM_ROTATABLE_BOND_COUNT>
7

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
5.29e-01 g/l

> <JCHEM_TRADITIONAL_IUPAC>
14-(2,3-dihydroxy-6-methylheptan-2-yl)-4,11-dihydroxy-2,15-dimethyl-5-[(3,4,5-trihydroxyoxan-2-yl)oxy]tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-9-en-8-one

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 16-APR-15   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   16-APR-15         0                                  
HETATM    1  C   UNK     0      -1.104  -9.089   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      -0.159  -7.873   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      -0.740  -6.447   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       1.366  -8.084   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       2.312  -6.868   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       3.837  -7.079   0.000  0.00  0.00           C+0
HETATM    7  O   UNK     0       4.417  -8.505   0.000  0.00  0.00           O+0
HETATM    8  C   UNK     0       4.782  -5.863   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       5.998  -6.808   0.000  0.00  0.00           C+0
HETATM   10  O   UNK     0       3.566  -4.918   0.000  0.00  0.00           O+0
HETATM   11  C   UNK     0       5.727  -4.647   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       5.299  -3.168   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       6.574  -2.304   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       7.790  -3.249   0.000  0.00  0.00           C+0
HETATM   15  O   UNK     0       8.159  -1.754   0.000  0.00  0.00           O+0
HETATM   16  C   UNK     0       9.306  -2.978   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       9.829  -1.529   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0      11.345  -1.258   0.000  0.00  0.00           C+0
HETATM   19  O   UNK     0      11.868   0.190   0.000  0.00  0.00           O+0
HETATM   20  C   UNK     0      12.338  -2.436   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0      13.854  -2.164   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0      14.846  -3.342   0.000  0.00  0.00           C+0
HETATM   23  O   UNK     0      16.362  -3.071   0.000  0.00  0.00           O+0
HETATM   24  C   UNK     0      16.886  -1.622   0.000  0.00  0.00           C+0
HETATM   25  O   UNK     0      15.893  -0.445   0.000  0.00  0.00           O+0
HETATM   26  C   UNK     0      16.416   1.003   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0      17.932   1.274   0.000  0.00  0.00           C+0
HETATM   28  O   UNK     0      18.455   2.723   0.000  0.00  0.00           O+0
HETATM   29  C   UNK     0      18.925   0.097   0.000  0.00  0.00           C+0
HETATM   30  O   UNK     0      20.441   0.368   0.000  0.00  0.00           O+0
HETATM   31  C   UNK     0      18.402  -1.351   0.000  0.00  0.00           C+0
HETATM   32  O   UNK     0      19.394  -2.529   0.000  0.00  0.00           O+0
HETATM   33  C   UNK     0      14.323  -4.790   0.000  0.00  0.00           C+0
HETATM   34  O   UNK     0      15.316  -5.967   0.000  0.00  0.00           O+0
HETATM   35  C   UNK     0      12.807  -5.061   0.000  0.00  0.00           C+0
HETATM   36  C   UNK     0      11.814  -3.884   0.000  0.00  0.00           C+0
HETATM   37  C   UNK     0      11.291  -5.332   0.000  0.00  0.00           C+0
HETATM   38  C   UNK     0      10.299  -4.155   0.000  0.00  0.00           C+0
HETATM   39  C   UNK     0       9.775  -5.603   0.000  0.00  0.00           C+0
HETATM   40  C   UNK     0       8.259  -5.874   0.000  0.00  0.00           C+0
HETATM   41  C   UNK     0       7.267  -4.697   0.000  0.00  0.00           C+0
HETATM   42  C   UNK     0       6.595  -6.083   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3    4                                                  
CONECT    3    2                                                            
CONECT    4    2    5                                                       
CONECT    5    4    6                                                       
CONECT    6    5    7    8                                                  
CONECT    7    6                                                            
CONECT    8    6    9   10   11                                             
CONECT    9    8                                                            
CONECT   10    8                                                            
CONECT   11    8   12   41                                                  
CONECT   12   11   13                                                       
CONECT   13   12   14                                                       
CONECT   14   13   15   16   41                                             
CONECT   15   14                                                            
CONECT   16   14   17   38                                                  
CONECT   17   16   18                                                       
CONECT   18   17   19   20                                                  
CONECT   19   18                                                            
CONECT   20   18   21   36                                                  
CONECT   21   20   22                                                       
CONECT   22   21   23   33                                                  
CONECT   23   22   24                                                       
CONECT   24   23   25   31                                                  
CONECT   25   24   26                                                       
CONECT   26   25   27                                                       
CONECT   27   26   28   29                                                  
CONECT   28   27                                                            
CONECT   29   27   30   31                                                  
CONECT   30   29                                                            
CONECT   31   29   24   32                                                  
CONECT   32   31                                                            
CONECT   33   22   34   35                                                  
CONECT   34   33                                                            
CONECT   35   33   36                                                       
CONECT   36   35   20   37   38                                             
CONECT   37   36                                                            
CONECT   38   36   16   39                                                  
CONECT   39   38   40                                                       
CONECT   40   39   41                                                       
CONECT   41   40   11   14   42                                             
CONECT   42   41                                                            
MASTER        0    0    0    0    0    0    0    0   42    0   92    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₃₂H₅₂O₁₀

Average Mass

596.7580 Da

Monoisotopic Mass

596.35605 Da

IUPAC Name

14-(2,3-dihydroxy-6-methylheptan-2-yl)-4,11-dihydroxy-2,15-dimethyl-5-[(3,4,5-trihydroxyoxan-2-yl)oxy]tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-9-en-8-one

Traditional Name

14-(2,3-dihydroxy-6-methylheptan-2-yl)-4,11-dihydroxy-2,15-dimethyl-5-[(3,4,5-trihydroxyoxan-2-yl)oxy]tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-9-en-8-one

CAS Registry Number

Not Available

SMILES

CC(C)CCC(O)C(C)(O)C1CCC2(O)C3=CC(=O)C4CC(OC5OCC(O)C(O)C5O)C(O)CC4(C)C3CCC12C

InChI Identifier

InChI=1S/C32H52O10/c1-16(2)6-7-25(36)31(5,39)24-9-11-32(40)18-12-20(33)19-13-23(42-28-27(38)26(37)22(35)15-41-28)21(34)14-29(19,3)17(18)8-10-30(24,32)4/h12,16-17,19,21-28,34-40H,6-11,13-15H2,1-5H3

InChI Key

YVYGCJBVFDRKJN-UHFFFAOYSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Limnanthes douglasii	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as steroidal glycosides. These are sterol lipids containing a carbohydrate moiety glycosidically linked to the steroid skeleton.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Steroids and steroid derivatives

Sub Class

Steroidal glycosides

Direct Parent

Steroidal glycosides

Alternative Parents

Substituents

Cholesterol
Cholestane-skeleton
Tetrahydroxy bile acid, alcohol, or derivatives
Steroidal glycoside
Ecdysteroid
Hydroxy bile acid, alcohol, or derivatives
Bile acid, alcohol, or derivatives
22-hydroxysteroid
20-hydroxysteroid
6-oxosteroid
2-hydroxysteroid
14-hydroxysteroid
Hydroxysteroid
Oxosteroid
Delta-7-steroid
Glycosyl compound
O-glycosyl compound
Cyclohexenone
Oxane
Monosaccharide
Tertiary alcohol
Cyclic alcohol
Ketone
Secondary alcohol
Polyol
Organoheterocyclic compound
Oxacycle
Acetal
Alcohol
Hydrocarbon derivative
Organic oxide
Carbonyl group
Organic oxygen compound
Organooxygen compound
Aliphatic heteropolycyclic compound

Molecular Framework

Aliphatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	0.73	ALOGPS
logP	0.94	ChemAxon
logS	-3	ALOGPS
pKa (Strongest Acidic)	12.21	ChemAxon
pKa (Strongest Basic)	-3.2	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	10	ChemAxon
Hydrogen Donor Count	7	ChemAxon
Polar Surface Area	177.14 Å²	ChemAxon
Rotatable Bond Count	7	ChemAxon
Refractivity	153.49 m³·mol⁻¹	ChemAxon
Polarizability	65.49 Å³	ChemAxon
Number of Rings	5	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	Yes	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

74379682

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for 1-(2,3-dihydroxy-6-methylheptan-2-yl)-3a,8-dihydroxy-9a,11a-dimethyl-7-[(3,4,5-trihydroxyoxan-2-yl)oxy]-1h,2h,3h,5ah,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-5-one (NP0314576)

MOL for NP0314576 (1-(2,3-dihydroxy-6-methylheptan-2-yl)-3a,8-dihydroxy-9a,11a-dimethyl-7-[(3,4,5-trihydroxyoxan-2-yl)oxy]-1h,2h,3h,5ah,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-5-one)

3D MOL for NP0314576 (1-(2,3-dihydroxy-6-methylheptan-2-yl)-3a,8-dihydroxy-9a,11a-dimethyl-7-[(3,4,5-trihydroxyoxan-2-yl)oxy]-1h,2h,3h,5ah,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-5-one)

3D SDF for NP0314576 (1-(2,3-dihydroxy-6-methylheptan-2-yl)-3a,8-dihydroxy-9a,11a-dimethyl-7-[(3,4,5-trihydroxyoxan-2-yl)oxy]-1h,2h,3h,5ah,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-5-one)

3D-SDF for NP0314576 (1-(2,3-dihydroxy-6-methylheptan-2-yl)-3a,8-dihydroxy-9a,11a-dimethyl-7-[(3,4,5-trihydroxyoxan-2-yl)oxy]-1h,2h,3h,5ah,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-5-one)

PDB for NP0314576 (1-(2,3-dihydroxy-6-methylheptan-2-yl)-3a,8-dihydroxy-9a,11a-dimethyl-7-[(3,4,5-trihydroxyoxan-2-yl)oxy]-1h,2h,3h,5ah,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-5-one)

3D PDB for NP0314576 (1-(2,3-dihydroxy-6-methylheptan-2-yl)-3a,8-dihydroxy-9a,11a-dimethyl-7-[(3,4,5-trihydroxyoxan-2-yl)oxy]-1h,2h,3h,5ah,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-5-one)

SMILES for NP0314576 (1-(2,3-dihydroxy-6-methylheptan-2-yl)-3a,8-dihydroxy-9a,11a-dimethyl-7-[(3,4,5-trihydroxyoxan-2-yl)oxy]-1h,2h,3h,5ah,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-5-one)

INCHI for NP0314576 (1-(2,3-dihydroxy-6-methylheptan-2-yl)-3a,8-dihydroxy-9a,11a-dimethyl-7-[(3,4,5-trihydroxyoxan-2-yl)oxy]-1h,2h,3h,5ah,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-5-one)

Structure for NP0314576 (1-(2,3-dihydroxy-6-methylheptan-2-yl)-3a,8-dihydroxy-9a,11a-dimethyl-7-[(3,4,5-trihydroxyoxan-2-yl)oxy]-1h,2h,3h,5ah,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-5-one)

3D Structure for NP0314576 (1-(2,3-dihydroxy-6-methylheptan-2-yl)-3a,8-dihydroxy-9a,11a-dimethyl-7-[(3,4,5-trihydroxyoxan-2-yl)oxy]-1h,2h,3h,5ah,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-5-one)