NP-MRD: Showing NP-Card for (1s,4s,7s,8s)-7-[(2r)-butan-2-yl]-4,5-dihydroxy-1-methyl-9,10-dioxa-6-azatricyclo[5.2.1.0⁴,⁸]dec-5-en-3-one (NP0309999)

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Record Information

Version

2.0

Created at

2022-09-11 04:57:52 UTC

Updated at

2022-09-11 04:57:52 UTC

NP-MRD ID

NP0309999

Secondary Accession Numbers

None

Natural Product Identification

Common Name

(1s,4s,7s,8s)-7-[(2r)-butan-2-yl]-4,5-dihydroxy-1-methyl-9,10-dioxa-6-azatricyclo[5.2.1.0⁴,⁸]dec-5-en-3-one

Description

(1S,4S,7S,8S)-7-[(2R)-butan-2-yl]-4,5-dihydroxy-1-methyl-9,10-dioxa-6-azatricyclo[5.2.1.0⁴,⁸]Dec-5-en-3-one belongs to the class of organic compounds known as oxepanes. Oxepanes are compounds containing an oxepane ring, which is a seven-member saturated aliphatic heterocycle with one oxygen and six carbon atoms. (1s,4s,7s,8s)-7-[(2r)-butan-2-yl]-4,5-dihydroxy-1-methyl-9,10-dioxa-6-azatricyclo[5.2.1.0⁴,⁸]dec-5-en-3-one is found in Cladobotryum rubrobrunnescens. Based on a literature review very few articles have been published on (1S,4S,7S,8S)-7-[(2R)-butan-2-yl]-4,5-dihydroxy-1-methyl-9,10-dioxa-6-azatricyclo[5.2.1.0⁴,⁸]Dec-5-en-3-one.

Structure

MOL 3D MOL SDF PDB SMILES InChI

     RDKit          3D

 35 37  0  0  0  0  0  0  0  0999 V2000
   -3.3882   -1.6965    0.7133 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9083   -1.3605    0.7098 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6816   -0.3474   -0.3645 C   0  0  1  0  0  0  0  0  0  0  0  0
   -2.4625    0.9223   -0.1593 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2295    0.0162   -0.5509 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.2015    1.1375   -1.4563 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.5882    2.0654   -1.0991 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7672    3.2438   -1.8325 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.2466    1.6869    0.1675 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.2748    2.7835    1.0420 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.6275    1.2127   -0.1264 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5850    1.9254    0.0351 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.8031   -0.1697   -0.6275 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6547   -0.9901   -0.0445 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.2179   -2.3818    0.2322 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1936   -0.4537    1.1336 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.3895    0.5784    0.7055 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.5625   -1.0402   -0.8891 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6197   -2.1501   -0.2901 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0105   -0.7854    0.8007 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6389   -2.4543    1.4782 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5731   -1.0282    1.7068 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3621   -2.2793    0.4414 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0249   -0.7902   -1.3254 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2851    1.2933    0.8765 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5378    0.8244   -0.3603 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0618    1.6622   -0.9107 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.3744    4.1184   -1.5141 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.3612    2.4347    1.9619 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.7863   -0.6055   -0.3997 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.7057   -0.1957   -1.7504 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.2745   -2.2139    0.5800 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.2312   -3.0038   -0.6671 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.6887   -2.8768    1.0707 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3472    0.9181    1.4412 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  1  0
  3  5  1  0
  5 18  1  0
 18 14  1  0
 14 15  1  1
 14 13  1  0
 13 11  1  0
 11 12  2  0
 11  9  1  0
  9 10  1  1
  9 17  1  0
 17 16  1  0
  9  7  1  0
  7  8  1  0
  7  6  2  0
 17  5  1  0
  5  6  1  6
 16 14  1  0
  1 19  1  0
  1 20  1  0
  1 21  1  0
  2 22  1  0
  2 23  1  0
  3 24  1  6
  4 25  1  0
  4 26  1  0
  4 27  1  0
 15 32  1  0
 15 33  1  0
 15 34  1  0
 13 30  1  0
 13 31  1  0
 10 29  1  0
 17 35  1  1
  8 28  1  0
M  END


  Mrv1652309112206572D          

 18 20  0  0  1  0            999 V2000
   -1.0582   -2.9285    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5723   -2.2617    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9069   -1.5076    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.7273   -1.4203    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4211   -0.8408    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.1259   -0.2928    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8861    0.5340    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3891    1.1879    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0176    0.5536    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.1145    1.3729    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.8302    0.7368    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0972    1.5174    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.4143    0.0418    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1673   -0.8701    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.8246   -1.3686    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7147   -0.5613    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.0017   -0.2198    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.3428   -1.3616    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  1  1  0  0  0
  5  3  1  1  0  0  0
  5  6  1  0  0  0  0
  6  7  2  0  0  0  0
  7  8  1  0  0  0  0
  7  9  1  0  0  0  0
  9 10  1  1  0  0  0
  9 11  1  0  0  0  0
 11 12  2  0  0  0  0
 11 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  1  0  0  0
 14 16  1  0  0  0  0
 17 16  1  6  0  0  0
  9 17  1  0  0  0  0
  5 17  1  0  0  0  0
 14 18  1  0  0  0  0
  5 18  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0309999

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CC[C@@H](C)[C@]12O[C@@]3(C)CC(=O)[C@](O)([C@@H]1O3)C(O)=N2

> <INCHI_IDENTIFIER>
InChI=1S/C12H17NO5/c1-4-6(2)12-8-11(16,9(15)13-12)7(14)5-10(3,17-8)18-12/h6,8,16H,4-5H2,1-3H3,(H,13,15)/t6-,8+,10+,11+,12+/m1/s1

> <INCHI_KEY>
KZYRZXGZPHCPCN-INTSTFLSSA-N

> <FORMULA>
C12H17NO5

> <MOLECULAR_WEIGHT>
255.27

> <EXACT_MASS>
255.110672651

> <JCHEM_ACCEPTOR_COUNT>
6

> <JCHEM_ATOM_COUNT>
35

> <JCHEM_AVERAGE_POLARIZABILITY>
24.9223746028281

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
2

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
(1S,4S,7S,8S)-7-[(2R)-butan-2-yl]-4,5-dihydroxy-1-methyl-9,10-dioxa-6-azatricyclo[5.2.1.0^{4,8}]dec-5-en-3-one

> <JCHEM_LOGP>
1.865400174

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
3

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
11.301521083029535

> <JCHEM_PKA_STRONGEST_ACIDIC>
1.8789237164910082

> <JCHEM_PKA_STRONGEST_BASIC>
-2.6476428605993516

> <JCHEM_POLAR_SURFACE_AREA>
88.35000000000002

> <JCHEM_REFRACTIVITY>
60.04690000000001

> <JCHEM_ROTATABLE_BOND_COUNT>
2

> <JCHEM_RULE_OF_FIVE>
1

> <JCHEM_TRADITIONAL_IUPAC>
(1S,4S,7S,8S)-7-[(2R)-butan-2-yl]-4,5-dihydroxy-1-methyl-9,10-dioxa-6-azatricyclo[5.2.1.0^{4,8}]dec-5-en-3-one

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 11-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   11-SEP-22         0                                  
HETATM    1  C   UNK     0      -1.975  -5.467   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      -1.068  -4.222   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      -1.693  -2.814   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      -3.224  -2.651   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      -0.786  -1.570   0.000  0.00  0.00           C+0
HETATM    6  N   UNK     0      -2.102  -0.547   0.000  0.00  0.00           N+0
HETATM    7  C   UNK     0      -1.654   0.997   0.000  0.00  0.00           C+0
HETATM    8  O   UNK     0      -2.593   2.217   0.000  0.00  0.00           O+0
HETATM    9  C   UNK     0      -0.033   1.033   0.000  0.00  0.00           C+0
HETATM   10  O   UNK     0      -0.214   2.563   0.000  0.00  0.00           O+0
HETATM   11  C   UNK     0       1.550   1.375   0.000  0.00  0.00           C+0
HETATM   12  O   UNK     0       2.048   2.832   0.000  0.00  0.00           O+0
HETATM   13  C   UNK     0       2.640   0.078   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       2.179  -1.624   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       3.406  -2.555   0.000  0.00  0.00           C+0
HETATM   16  O   UNK     0       1.334  -1.048   0.000  0.00  0.00           O+0
HETATM   17  C   UNK     0       0.003  -0.410   0.000  0.00  0.00           C+0
HETATM   18  O   UNK     0       0.640  -2.542   0.000  0.00  0.00           O+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4    5                                                  
CONECT    4    3                                                            
CONECT    5    3    6   17   18                                             
CONECT    6    5    7                                                       
CONECT    7    6    8    9                                                  
CONECT    8    7                                                            
CONECT    9    7   10   11   17                                             
CONECT   10    9                                                            
CONECT   11    9   12   13                                                  
CONECT   12   11                                                            
CONECT   13   11   14                                                       
CONECT   14   13   15   16   18                                             
CONECT   15   14                                                            
CONECT   16   14   17                                                       
CONECT   17   16    9    5                                                  
CONECT   18   14    5                                                       
MASTER        0    0    0    0    0    0    0    0   18    0   40    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₁₂H₁₇NO₅

Average Mass

255.2700 Da

Monoisotopic Mass

255.11067 Da

IUPAC Name

(1S,4S,7S,8S)-7-[(2R)-butan-2-yl]-4,5-dihydroxy-1-methyl-9,10-dioxa-6-azatricyclo[5.2.1.0^{4,8}]dec-5-en-3-one

Traditional Name

(1S,4S,7S,8S)-7-[(2R)-butan-2-yl]-4,5-dihydroxy-1-methyl-9,10-dioxa-6-azatricyclo[5.2.1.0^{4,8}]dec-5-en-3-one

CAS Registry Number

Not Available

SMILES

CC[C@@H](C)[C@]12O[C@@]3(C)CC(=O)[C@](O)([C@@H]1O3)C(O)=N2

InChI Identifier

InChI=1S/C12H17NO5/c1-4-6(2)12-8-11(16,9(15)13-12)7(14)5-10(3,17-8)18-12/h6,8,16H,4-5H2,1-3H3,(H,13,15)/t6-,8+,10+,11+,12+/m1/s1

InChI Key

KZYRZXGZPHCPCN-INTSTFLSSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Cladobotryum rubrobrunnescens	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as oxepanes. Oxepanes are compounds containing an oxepane ring, which is a seven-member saturated aliphatic heterocycle with one oxygen and six carbon atoms.

Kingdom

Organic compounds

Super Class

Organoheterocyclic compounds

Class

Oxepanes

Sub Class

Not Available

Direct Parent

Oxepanes

Alternative Parents

Substituents

Ketal
Oxepane
2-pyrrolidone
Pyrrolidone
Oxane
Tertiary alcohol
Pyrrolidine
Meta-dioxolane
Secondary carboxylic acid amide
Lactam
Ketone
Carboxamide group
Oxacycle
Azacycle
Carboxylic acid derivative
Acetal
Organic nitrogen compound
Organic oxygen compound
Organopnictogen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Organonitrogen compound
Carbonyl group
Alcohol
Aliphatic heteropolycyclic compound

Molecular Framework

Aliphatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	1.87	ChemAxon
pKa (Strongest Acidic)	1.88	ChemAxon
pKa (Strongest Basic)	-2.6	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	6	ChemAxon
Hydrogen Donor Count	2	ChemAxon
Polar Surface Area	88.35 Å²	ChemAxon
Rotatable Bond Count	2	ChemAxon
Refractivity	60.05 m³·mol⁻¹	ChemAxon
Polarizability	24.92 Å³	ChemAxon
Number of Rings	3	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

163104823

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for (1s,4s,7s,8s)-7-[(2r)-butan-2-yl]-4,5-dihydroxy-1-methyl-9,10-dioxa-6-azatricyclo[5.2.1.0⁴,⁸]dec-5-en-3-one (NP0309999)

MOL for NP0309999 ((1s,4s,7s,8s)-7-[(2r)-butan-2-yl]-4,5-dihydroxy-1-methyl-9,10-dioxa-6-azatricyclo[5.2.1.0⁴,⁸]dec-5-en-3-one)

3D MOL for NP0309999 ((1s,4s,7s,8s)-7-[(2r)-butan-2-yl]-4,5-dihydroxy-1-methyl-9,10-dioxa-6-azatricyclo[5.2.1.0⁴,⁸]dec-5-en-3-one)

3D SDF for NP0309999 ((1s,4s,7s,8s)-7-[(2r)-butan-2-yl]-4,5-dihydroxy-1-methyl-9,10-dioxa-6-azatricyclo[5.2.1.0⁴,⁸]dec-5-en-3-one)

3D-SDF for NP0309999 ((1s,4s,7s,8s)-7-[(2r)-butan-2-yl]-4,5-dihydroxy-1-methyl-9,10-dioxa-6-azatricyclo[5.2.1.0⁴,⁸]dec-5-en-3-one)

PDB for NP0309999 ((1s,4s,7s,8s)-7-[(2r)-butan-2-yl]-4,5-dihydroxy-1-methyl-9,10-dioxa-6-azatricyclo[5.2.1.0⁴,⁸]dec-5-en-3-one)

3D PDB for NP0309999 ((1s,4s,7s,8s)-7-[(2r)-butan-2-yl]-4,5-dihydroxy-1-methyl-9,10-dioxa-6-azatricyclo[5.2.1.0⁴,⁸]dec-5-en-3-one)

SMILES for NP0309999 ((1s,4s,7s,8s)-7-[(2r)-butan-2-yl]-4,5-dihydroxy-1-methyl-9,10-dioxa-6-azatricyclo[5.2.1.0⁴,⁸]dec-5-en-3-one)

INCHI for NP0309999 ((1s,4s,7s,8s)-7-[(2r)-butan-2-yl]-4,5-dihydroxy-1-methyl-9,10-dioxa-6-azatricyclo[5.2.1.0⁴,⁸]dec-5-en-3-one)

Structure for NP0309999 ((1s,4s,7s,8s)-7-[(2r)-butan-2-yl]-4,5-dihydroxy-1-methyl-9,10-dioxa-6-azatricyclo[5.2.1.0⁴,⁸]dec-5-en-3-one)

3D Structure for NP0309999 ((1s,4s,7s,8s)-7-[(2r)-butan-2-yl]-4,5-dihydroxy-1-methyl-9,10-dioxa-6-azatricyclo[5.2.1.0⁴,⁸]dec-5-en-3-one)