NP-MRD: Showing NP-Card for 2-(3,4-dihydroxyphenyl)-5-hydroxy-7-{[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,3-dihydro-1-benzopyran-4-one (NP0309647)

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Record Information

Version

2.0

Created at

2022-09-11 04:23:31 UTC

Updated at

2022-09-11 04:23:31 UTC

NP-MRD ID

NP0309647

Secondary Accession Numbers

None

Natural Product Identification

Common Name

2-(3,4-dihydroxyphenyl)-5-hydroxy-7-{[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,3-dihydro-1-benzopyran-4-one

Description

Eriodictyol-7-O-glucoside belongs to the class of organic compounds known as flavonoid-7-o-glycosides. These are phenolic compounds containing a flavonoid moiety which is O-glycosidically linked to carbohydrate moiety at the C7-position. Eriodictyol-7-O-glucoside is an extremely weak basic (essentially neutral) compound (based on its pKa).

Structure

MOL 3D MOL SDF PDB SMILES InChI

Eriodictyol 7-O-glucoside
  Mrv1572001071617292D          

 32 35  0  0  1  0            999 V2000
   -2.1434   -3.2227    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289   -2.8102    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289   -1.9852    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.7145   -1.5727    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -0.7477    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.0000   -0.3352    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.7477    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -1.5727    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -1.9852    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -2.8102    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -1.5727    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -1.9852    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -2.8102    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -1.5727    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -0.7477    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -0.3352    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -0.7477    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -0.3352    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868   -0.3352    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013   -0.7477    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158   -0.3352    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4302   -0.7477    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158    0.4898    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4302    0.9023    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013    0.9023    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868    0.4898    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289   -0.3352    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -1.4289    0.4898    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1434   -0.7477    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -2.8579   -0.3352    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1434   -1.5727    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -2.8579   -1.9852    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  3  2  1  6  0  0  0
  3  4  1  0  0  0  0
  4  5  1  0  0  0  0
  5  6  1  1  0  0  0
  6  7  1  0  0  0  0
  7  8  2  0  0  0  0
  8  9  1  0  0  0  0
  9 10  1  0  0  0  0
  9 11  2  0  0  0  0
 11 12  1  0  0  0  0
 12 13  2  0  0  0  0
 12 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 11 17  1  0  0  0  0
 17 18  2  0  0  0  0
  7 18  1  0  0  0  0
 15 19  1  0  0  0  0
 19 20  2  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 21 23  2  0  0  0  0
 23 24  1  0  0  0  0
 23 25  1  0  0  0  0
 25 26  2  0  0  0  0
 19 26  1  0  0  0  0
  5 27  1  0  0  0  0
 27 28  1  1  0  0  0
 27 29  1  0  0  0  0
 29 30  1  6  0  0  0
 29 31  1  0  0  0  0
  3 31  1  0  0  0  0
 31 32  1  1  0  0  0
M  END

     RDKit          3D

 54 57  0  0  0  0  0  0  0  0999 V2000
    3.4956   -2.9088   -0.7443 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.7504   -2.6575    0.2169 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.0384   -3.1211    1.6114 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7986   -1.9748    2.5700 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.0330   -1.1318    2.6072 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.9051   -1.2952    3.6644 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0602   -0.5378    3.7421 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.3453    0.3882    2.7575 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.4958    1.1396    2.8388 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.4741    0.5382    1.7193 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7913    1.4828    0.7400 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.3179   -0.2138    1.6332 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7110   -1.1678    2.2408 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.0566   -1.1280    1.0332 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0710   -0.3571    0.8824 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7159   -0.3370   -0.3597 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8234    0.4358   -0.4650 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6657    0.6628   -1.5363 C   0  0  1  0  0  0  0  0  0  0  0  0
   -3.9258    0.1725   -1.2002 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.7931    1.1402   -0.7383 C   0  0  2  0  0  0  0  0  0  0  0  0
   -6.0854    0.4473   -0.3591 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.6775   -0.2096   -1.4151 O   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1490    2.1484   -1.8298 C   0  0  1  0  0  0  0  0  0  0  0  0
   -5.3667    3.4088   -1.2830 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9710    2.2782   -2.8053 C   0  0  2  0  0  0  0  0  0  0  0  0
   -3.9701    1.2717   -3.7464 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7250    2.1229   -1.9517 C   0  0  1  0  0  0  0  0  0  0  0  0
   -2.7315    2.9860   -0.8763 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2470   -1.0641   -1.4133 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9073   -1.8515   -1.2538 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3590   -2.5683   -2.3094 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.5475   -1.8769   -0.0367 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0843   -3.4476    1.6984 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.3062   -3.9183    1.8450 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.6108   -2.4043    3.5795 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.6832   -2.0269    4.4457 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.7137   -0.6919    4.5774 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.1375    1.0306    3.6015 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.2031    1.6573   -0.0605 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.6551   -0.0710    0.8045 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4529    0.2186    1.6960 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3626    0.1094   -2.4448 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4302    1.6503    0.1779 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.8333    1.1840    0.0443 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.9077   -0.2561    0.5019 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.3587    0.3544   -1.8153 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.0027    1.7615   -2.4012 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1131    4.1449   -1.8855 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9813    3.2602   -3.3090 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4388    0.4516   -3.4730 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8285    2.3520   -2.5629 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2234    2.6414   -0.1139 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7337   -1.0476   -2.3468 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.1042   -3.1750   -2.4484 H   0  0  0  0  0  0  0  0  0  0  0  0
 22 21  1  0
 21 20  1  0
 20 19  1  0
 19 18  1  0
 18 17  1  0
 17 16  1  0
 16 29  2  0
 29 30  1  0
 30 31  1  0
 30 32  2  0
 32  2  1  0
  2  1  2  0
  2  3  1  0
  3  4  1  0
  4 13  1  0
 13 14  1  0
 14 15  2  0
  4  5  1  0
  5 12  2  0
 12 10  1  0
 10 11  1  0
 10  8  2  0
  8  9  1  0
  8  7  1  0
  7  6  2  0
 18 27  1  0
 27 28  1  0
 27 25  1  0
 25 26  1  0
 25 23  1  0
 23 24  1  0
 23 20  1  0
 15 16  1  0
  6  5  1  0
 14 32  1  0
 22 46  1  0
 21 44  1  0
 21 45  1  0
 20 43  1  1
 18 42  1  6
 29 53  1  0
 31 54  1  0
  3 33  1  0
  3 34  1  0
  4 35  1  1
 15 41  1  0
 12 40  1  0
 11 39  1  0
  9 38  1  0
  7 37  1  0
  6 36  1  0
 27 51  1  6
 28 52  1  0
 25 49  1  6
 26 50  1  0
 23 47  1  6
 24 48  1  0
M  END

Eriodictyol 7-O-glucoside
  Mrv1572001071617292D          

 32 35  0  0  1  0            999 V2000
   -2.1434   -3.2227    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289   -2.8102    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289   -1.9852    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.7145   -1.5727    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -0.7477    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.0000   -0.3352    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.7477    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -1.5727    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -1.9852    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -2.8102    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -1.5727    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -1.9852    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -2.8102    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -1.5727    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -0.7477    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -0.3352    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -0.7477    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -0.3352    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868   -0.3352    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013   -0.7477    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158   -0.3352    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4302   -0.7477    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158    0.4898    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4302    0.9023    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013    0.9023    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868    0.4898    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289   -0.3352    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -1.4289    0.4898    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1434   -0.7477    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -2.8579   -0.3352    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1434   -1.5727    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -2.8579   -1.9852    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  3  2  1  6  0  0  0
  3  4  1  0  0  0  0
  4  5  1  0  0  0  0
  5  6  1  1  0  0  0
  6  7  1  0  0  0  0
  7  8  2  0  0  0  0
  8  9  1  0  0  0  0
  9 10  1  0  0  0  0
  9 11  2  0  0  0  0
 11 12  1  0  0  0  0
 12 13  2  0  0  0  0
 12 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 11 17  1  0  0  0  0
 17 18  2  0  0  0  0
  7 18  1  0  0  0  0
 15 19  1  0  0  0  0
 19 20  2  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 21 23  2  0  0  0  0
 23 24  1  0  0  0  0
 23 25  1  0  0  0  0
 25 26  2  0  0  0  0
 19 26  1  0  0  0  0
  5 27  1  0  0  0  0
 27 28  1  1  0  0  0
 27 29  1  0  0  0  0
 29 30  1  6  0  0  0
 29 31  1  0  0  0  0
  3 31  1  0  0  0  0
 31 32  1  1  0  0  0
M  END
> <DATABASE_ID>
NP0309647

> <DATABASE_NAME>
NP-MRD

> <SMILES>
OC[C@H]1O[C@H](OC2=CC(O)=C3C(=O)CC(OC3=C2)C2=CC(O)=C(O)C=C2)[C@H](O)[C@@H](O)[C@@H]1O

> <INCHI_IDENTIFIER>
InChI=1S/C21H22O11/c22-7-16-18(27)19(28)20(29)21(32-16)30-9-4-12(25)17-13(26)6-14(31-15(17)5-9)8-1-2-10(23)11(24)3-8/h1-5,14,16,18-25,27-29H,6-7H2/t14?,16-,18-,19+,20-,21+/m1/s1

> <INCHI_KEY>
RAFHNDRXYHOLSH-MMQMLBMASA-N

> <FORMULA>
C21H22O11

> <MOLECULAR_WEIGHT>
450.396

> <EXACT_MASS>
450.116211528

> <JCHEM_ACCEPTOR_COUNT>
11

> <JCHEM_ATOM_COUNT>
54

> <JCHEM_AVERAGE_POLARIZABILITY>
43.72565127124993

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
7

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
2-(3,4-dihydroxyphenyl)-5-hydroxy-7-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3,4-dihydro-2H-1-benzopyran-4-one

> <ALOGPS_LOGP>
0.00

> <JCHEM_LOGP>
0.2634746353333332

> <ALOGPS_LOGS>
-2.40

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
4

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
9.314679406597454

> <JCHEM_PKA_STRONGEST_ACIDIC>
8.536152802860736

> <JCHEM_PKA_STRONGEST_BASIC>
-2.9810923437586574

> <JCHEM_POLAR_SURFACE_AREA>
186.37

> <JCHEM_REFRACTIVITY>
105.41510000000001

> <JCHEM_ROTATABLE_BOND_COUNT>
4

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
1.77e+00 g/l

> <JCHEM_TRADITIONAL_IUPAC>
2-(3,4-dihydroxyphenyl)-5-hydroxy-7-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,3-dihydro-1-benzopyran-4-one

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 07-JAN-16   NONE
TITLE     NULL                                                        
COMPND    MOLECULE: Eriodictyol 7-O-glucoside                         
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   07-JAN-16         0                                  
HETATM    1  O   UNK     0      -4.001  -6.016   0.000  0.00  0.00           O+0
HETATM    2  C   UNK     0      -2.667  -5.246   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      -2.667  -3.706   0.000  0.00  0.00           C+0
HETATM    4  O   UNK     0      -1.334  -2.936   0.000  0.00  0.00           O+0
HETATM    5  C   UNK     0      -1.334  -1.396   0.000  0.00  0.00           C+0
HETATM    6  O   UNK     0       0.000  -0.626   0.000  0.00  0.00           O+0
HETATM    7  C   UNK     0       1.334  -1.396   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       1.334  -2.936   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       2.667  -3.706   0.000  0.00  0.00           C+0
HETATM   10  O   UNK     0       2.667  -5.246   0.000  0.00  0.00           O+0
HETATM   11  C   UNK     0       4.001  -2.936   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       5.335  -3.706   0.000  0.00  0.00           C+0
HETATM   13  O   UNK     0       5.335  -5.246   0.000  0.00  0.00           O+0
HETATM   14  C   UNK     0       6.668  -2.936   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       6.668  -1.396   0.000  0.00  0.00           C+0
HETATM   16  O   UNK     0       5.335  -0.626   0.000  0.00  0.00           O+0
HETATM   17  C   UNK     0       4.001  -1.396   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       2.667  -0.626   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       8.002  -0.626   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0       9.336  -1.396   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0      10.669  -0.626   0.000  0.00  0.00           C+0
HETATM   22  O   UNK     0      12.003  -1.396   0.000  0.00  0.00           O+0
HETATM   23  C   UNK     0      10.669   0.914   0.000  0.00  0.00           C+0
HETATM   24  O   UNK     0      12.003   1.684   0.000  0.00  0.00           O+0
HETATM   25  C   UNK     0       9.336   1.684   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0       8.002   0.914   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0      -2.667  -0.626   0.000  0.00  0.00           C+0
HETATM   28  O   UNK     0      -2.667   0.914   0.000  0.00  0.00           O+0
HETATM   29  C   UNK     0      -4.001  -1.396   0.000  0.00  0.00           C+0
HETATM   30  O   UNK     0      -5.335  -0.626   0.000  0.00  0.00           O+0
HETATM   31  C   UNK     0      -4.001  -2.936   0.000  0.00  0.00           C+0
HETATM   32  O   UNK     0      -5.335  -3.706   0.000  0.00  0.00           O+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4   31                                                  
CONECT    4    3    5                                                       
CONECT    5    4    6   27                                                  
CONECT    6    5    7                                                       
CONECT    7    6    8   18                                                  
CONECT    8    7    9                                                       
CONECT    9    8   10   11                                                  
CONECT   10    9                                                            
CONECT   11    9   12   17                                                  
CONECT   12   11   13   14                                                  
CONECT   13   12                                                            
CONECT   14   12   15                                                       
CONECT   15   14   16   19                                                  
CONECT   16   15   17                                                       
CONECT   17   16   11   18                                                  
CONECT   18   17    7                                                       
CONECT   19   15   20   26                                                  
CONECT   20   19   21                                                       
CONECT   21   20   22   23                                                  
CONECT   22   21                                                            
CONECT   23   21   24   25                                                  
CONECT   24   23                                                            
CONECT   25   23   26                                                       
CONECT   26   25   19                                                       
CONECT   27    5   28   29                                                  
CONECT   28   27                                                            
CONECT   29   27   30   31                                                  
CONECT   30   29                                                            
CONECT   31   29    3   32                                                  
CONECT   32   31                                                            
MASTER        0    0    0    0    0    0    0    0   32    0   70    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₂₁H₂₂O₁₁

Average Mass

450.3960 Da

Monoisotopic Mass

450.11621 Da

IUPAC Name

2-(3,4-dihydroxyphenyl)-5-hydroxy-7-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3,4-dihydro-2H-1-benzopyran-4-one

Traditional Name

2-(3,4-dihydroxyphenyl)-5-hydroxy-7-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,3-dihydro-1-benzopyran-4-one

CAS Registry Number

Not Available

SMILES

OC[C@H]1O[C@H](OC2=CC(O)=C3C(=O)CC(OC3=C2)C2=CC(O)=C(O)C=C2)[C@H](O)[C@@H](O)[C@@H]1O

InChI Identifier

InChI=1S/C21H22O11/c22-7-16-18(27)19(28)20(29)21(32-16)30-9-4-12(25)17-13(26)6-14(31-15(17)5-9)8-1-2-10(23)11(24)3-8/h1-5,14,16,18-25,27-29H,6-7H2/t14?,16-,18-,19+,20-,21+/m1/s1

InChI Key

RAFHNDRXYHOLSH-MMQMLBMASA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Not Available

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as flavonoid-7-o-glycosides. These are phenolic compounds containing a flavonoid moiety which is O-glycosidically linked to carbohydrate moiety at the C7-position.

Kingdom

Organic compounds

Super Class

Phenylpropanoids and polyketides

Class

Flavonoids

Sub Class

Flavonoid glycosides

Direct Parent

Flavonoid-7-O-glycosides

Alternative Parents

Substituents

Flavonoid-7-o-glycoside
3'-hydroxyflavonoid
4'-hydroxyflavonoid
5-hydroxyflavonoid
Hydroxyflavonoid
Flavanone
Flavan
Phenolic glycoside
Fatty acyl glycoside of mono- or disaccharide
Fatty acyl glycoside
Alkyl glycoside
Hexose monosaccharide
Glycosyl compound
O-glycosyl compound
Chromone
Benzopyran
Chromane
1-benzopyran
Catechol
Aryl alkyl ketone
Aryl ketone
Phenol
Alkyl aryl ether
1-hydroxy-4-unsubstituted benzenoid
1-hydroxy-2-unsubstituted benzenoid
Benzenoid
Fatty acyl
Monosaccharide
Monocyclic benzene moiety
Oxane
Vinylogous acid
Secondary alcohol
Ketone
Polyol
Acetal
Organoheterocyclic compound
Ether
Oxacycle
Organic oxygen compound
Organic oxide
Aldehyde
Alcohol
Primary alcohol
Hydrocarbon derivative
Organooxygen compound
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	0	ALOGPS
logP	0.26	ChemAxon
logS	-2.4	ALOGPS
pKa (Strongest Acidic)	8.54	ChemAxon
pKa (Strongest Basic)	-3	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	11	ChemAxon
Hydrogen Donor Count	7	ChemAxon
Polar Surface Area	186.37 Å²	ChemAxon
Rotatable Bond Count	4	ChemAxon
Refractivity	105.42 m³·mol⁻¹	ChemAxon
Polarizability	43.73 Å³	ChemAxon
Number of Rings	4	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

3084727

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for 2-(3,4-dihydroxyphenyl)-5-hydroxy-7-{[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,3-dihydro-1-benzopyran-4-one (NP0309647)

MOL for NP0309647 (2-(3,4-dihydroxyphenyl)-5-hydroxy-7-{[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,3-dihydro-1-benzopyran-4-one)

3D MOL for NP0309647 (2-(3,4-dihydroxyphenyl)-5-hydroxy-7-{[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,3-dihydro-1-benzopyran-4-one)

3D SDF for NP0309647 (2-(3,4-dihydroxyphenyl)-5-hydroxy-7-{[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,3-dihydro-1-benzopyran-4-one)

3D-SDF for NP0309647 (2-(3,4-dihydroxyphenyl)-5-hydroxy-7-{[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,3-dihydro-1-benzopyran-4-one)

PDB for NP0309647 (2-(3,4-dihydroxyphenyl)-5-hydroxy-7-{[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,3-dihydro-1-benzopyran-4-one)

3D PDB for NP0309647 (2-(3,4-dihydroxyphenyl)-5-hydroxy-7-{[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,3-dihydro-1-benzopyran-4-one)

SMILES for NP0309647 (2-(3,4-dihydroxyphenyl)-5-hydroxy-7-{[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,3-dihydro-1-benzopyran-4-one)

INCHI for NP0309647 (2-(3,4-dihydroxyphenyl)-5-hydroxy-7-{[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,3-dihydro-1-benzopyran-4-one)

Structure for NP0309647 (2-(3,4-dihydroxyphenyl)-5-hydroxy-7-{[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,3-dihydro-1-benzopyran-4-one)

3D Structure for NP0309647 (2-(3,4-dihydroxyphenyl)-5-hydroxy-7-{[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,3-dihydro-1-benzopyran-4-one)