NP-MRD: Showing NP-Card for (2e)-3-(5-{[(2e,4e)-hexa-2,4-dienoyloxy]methyl}-3-(hydroxymethyl)-4-methoxy-6-oxopyran-2-yl)prop-2-enoic acid (NP0306380)

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Record Information

Version

2.0

Created at

2022-09-10 22:48:55 UTC

Updated at

2022-09-10 22:48:55 UTC

NP-MRD ID

NP0306380

Secondary Accession Numbers

None

Natural Product Identification

Common Name

(2e)-3-(5-{[(2e,4e)-hexa-2,4-dienoyloxy]methyl}-3-(hydroxymethyl)-4-methoxy-6-oxopyran-2-yl)prop-2-enoic acid

Description

Islandic acid I, also known as islandate I, belongs to the class of organic compounds known as pyranones and derivatives. Pyranones and derivatives are compounds containing a pyran ring which bears a ketone. (2e)-3-(5-{[(2e,4e)-hexa-2,4-dienoyloxy]methyl}-3-(hydroxymethyl)-4-methoxy-6-oxopyran-2-yl)prop-2-enoic acid is found in Talaromyces islandicus. Based on a literature review very few articles have been published on Islandic acid I.

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652309112200482D          

 25 25  0  0  0  0            999 V2000
   -2.1434    6.1875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289    5.7750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289    4.9500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    3.7125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    3.3000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    3.7125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    2.4750    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434    1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    0.0000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  2  0  0  0  0
  3  4  1  0  0  0  0
  4  5  2  0  0  0  0
  5  6  1  0  0  0  0
  6  7  2  0  0  0  0
  6  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  1  0  0  0  0
 10 11  2  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  0  0  0  0
 11 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 14 17  2  0  0  0  0
 17 18  1  0  0  0  0
 18 19  2  0  0  0  0
 19 20  1  0  0  0  0
 20 21  2  0  0  0  0
 20 22  1  0  0  0  0
 17 23  1  0  0  0  0
 23 24  1  0  0  0  0
 10 24  1  0  0  0  0
 24 25  2  0  0  0  0
M  END

     RDKit          3D

 43 43  0  0  0  0  0  0  0  0999 V2000
    7.8096    1.8230   -0.0890 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.5572    1.2579    0.4526 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.5989    0.8364   -0.3376 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3573    0.2578    0.1578 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4570   -0.1785   -0.6902 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1896   -0.7756   -0.3818 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4182   -1.1332   -1.3016 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.6976   -1.0249    0.9231 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.4458   -1.6765    0.9221 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6587   -0.8869    0.3489 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8450   -1.5297    0.0450 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9208   -2.8396    0.0771 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1390   -3.9740    0.7300 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9247   -0.6875   -0.3049 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1673   -1.4355   -0.5468 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0680   -2.1854   -1.7823 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8030    0.6618   -0.3366 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9606    1.5289   -0.6735 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8913    2.8462   -0.3709 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9670    3.7494   -0.6548 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.0162    3.2315   -1.1623 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9515    5.0812   -0.4085 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6491    1.1939   -0.0409 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5959    0.4735    0.2947 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4956    1.0582    0.5915 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.1036    1.1269   -0.9305 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.5988    2.7992   -0.5139 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.6121    1.9113    0.6717 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.3776    1.1717    1.5347 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.7235    0.9058   -1.4086 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.1692    0.1629    1.2149 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.7116   -0.0632   -1.7642 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.5263   -2.7177    0.6812 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.2151   -1.7246    2.0905 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3446   -4.8184   -0.0378 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9090   -4.0172    1.5063 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2316   -4.4318    1.2513 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5236   -1.9757    0.2573 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9999   -0.6893   -0.9453 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3450   -3.1290   -1.4139 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.8625    1.2168   -1.1350 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9844    3.1805    0.1068 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3057    5.4194    0.3029 H   0  0  0  0  0  0  0  0  0  0  0  0
 13 12  1  0
 12 11  1  0
 11 10  2  0
 10  9  1  0
  9  8  1  0
  8  6  1  0
  6  7  2  0
  6  5  1  0
  5  4  2  0
  4  3  1  0
  3  2  2  0
  2  1  1  0
 10 24  1  0
 24 25  2  0
 24 23  1  0
 23 17  1  0
 17 18  1  0
 18 19  2  0
 19 20  1  0
 20 22  1  0
 20 21  2  0
 17 14  2  0
 14 15  1  0
 15 16  1  0
 14 11  1  0
 13 35  1  0
 13 36  1  0
 13 37  1  0
  9 33  1  0
  9 34  1  0
  5 32  1  0
  4 31  1  0
  3 30  1  0
  2 29  1  0
  1 26  1  0
  1 27  1  0
  1 28  1  0
 18 41  1  0
 19 42  1  0
 22 43  1  0
 15 38  1  0
 15 39  1  0
 16 40  1  0
M  END


  Mrv1652309112200482D          

 25 25  0  0  0  0            999 V2000
   -2.1434    6.1875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289    5.7750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289    4.9500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    3.7125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    3.3000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    3.7125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    2.4750    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434    1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    0.0000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  2  0  0  0  0
  3  4  1  0  0  0  0
  4  5  2  0  0  0  0
  5  6  1  0  0  0  0
  6  7  2  0  0  0  0
  6  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  1  0  0  0  0
 10 11  2  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  0  0  0  0
 11 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 14 17  2  0  0  0  0
 17 18  1  0  0  0  0
 18 19  2  0  0  0  0
 19 20  1  0  0  0  0
 20 21  2  0  0  0  0
 20 22  1  0  0  0  0
 17 23  1  0  0  0  0
 23 24  1  0  0  0  0
 10 24  1  0  0  0  0
 24 25  2  0  0  0  0
M  END
> <DATABASE_ID>
NP0306380

> <DATABASE_NAME>
NP-MRD

> <SMILES>
COC1=C(COC(=O)\C=C\C=C\C)C(=O)OC(\C=C\C(O)=O)=C1CO

> <INCHI_IDENTIFIER>
InChI=1S/C17H18O8/c1-3-4-5-6-15(21)24-10-12-16(23-2)11(9-18)13(25-17(12)22)7-8-14(19)20/h3-8,18H,9-10H2,1-2H3,(H,19,20)/b4-3+,6-5+,8-7+

> <INCHI_KEY>
OUBRQRPPZKZTIX-ARQDATDDSA-N

> <FORMULA>
C17H18O8

> <MOLECULAR_WEIGHT>
350.323

> <EXACT_MASS>
350.10016754

> <JCHEM_ACCEPTOR_COUNT>
6

> <JCHEM_ATOM_COUNT>
43

> <JCHEM_AVERAGE_POLARIZABILITY>
35.25207009146994

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
2

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
(2E)-3-(3-{[(2E,4E)-hexa-2,4-dienoyloxy]methyl}-5-(hydroxymethyl)-4-methoxy-2-oxo-2H-pyran-6-yl)prop-2-enoic acid

> <JCHEM_LOGP>
0.8844611499999997

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
1

> <JCHEM_PHYSIOLOGICAL_CHARGE>
-1

> <JCHEM_PKA>
14.913886317344776

> <JCHEM_PKA_STRONGEST_ACIDIC>
4.026517737792817

> <JCHEM_PKA_STRONGEST_BASIC>
-2.8369640449182922

> <JCHEM_POLAR_SURFACE_AREA>
119.36000000000001

> <JCHEM_REFRACTIVITY>
92.26759999999999

> <JCHEM_ROTATABLE_BOND_COUNT>
9

> <JCHEM_RULE_OF_FIVE>
1

> <JCHEM_TRADITIONAL_IUPAC>
(2E)-3-(5-{[(2E,4E)-hexa-2,4-dienoyloxy]methyl}-3-(hydroxymethyl)-4-methoxy-6-oxopyran-2-yl)prop-2-enoic acid

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 11-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   11-SEP-22         0                                  
HETATM    1  C   UNK     0      -4.001  11.550   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      -2.667  10.780   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      -2.667   9.240   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      -1.334   8.470   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      -1.334   6.930   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       0.000   6.160   0.000  0.00  0.00           C+0
HETATM    7  O   UNK     0       1.334   6.930   0.000  0.00  0.00           O+0
HETATM    8  O   UNK     0       0.000   4.620   0.000  0.00  0.00           O+0
HETATM    9  C   UNK     0       1.334   3.850   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       1.334   2.310   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       2.667   1.540   0.000  0.00  0.00           C+0
HETATM   12  O   UNK     0       4.001   2.310   0.000  0.00  0.00           O+0
HETATM   13  C   UNK     0       5.335   1.540   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       2.667  -0.000   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       4.001  -0.770   0.000  0.00  0.00           C+0
HETATM   16  O   UNK     0       4.001  -2.310   0.000  0.00  0.00           O+0
HETATM   17  C   UNK     0       1.334  -0.770   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       1.334  -2.310   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0      -0.000  -3.080   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0      -0.000  -4.620   0.000  0.00  0.00           C+0
HETATM   21  O   UNK     0       1.334  -5.390   0.000  0.00  0.00           O+0
HETATM   22  O   UNK     0      -1.334  -5.390   0.000  0.00  0.00           O+0
HETATM   23  O   UNK     0       0.000   0.000   0.000  0.00  0.00           O+0
HETATM   24  C   UNK     0       0.000   1.540   0.000  0.00  0.00           C+0
HETATM   25  O   UNK     0      -1.334   2.310   0.000  0.00  0.00           O+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4                                                       
CONECT    4    3    5                                                       
CONECT    5    4    6                                                       
CONECT    6    5    7    8                                                  
CONECT    7    6                                                            
CONECT    8    6    9                                                       
CONECT    9    8   10                                                       
CONECT   10    9   11   24                                                  
CONECT   11   10   12   14                                                  
CONECT   12   11   13                                                       
CONECT   13   12                                                            
CONECT   14   11   15   17                                                  
CONECT   15   14   16                                                       
CONECT   16   15                                                            
CONECT   17   14   18   23                                                  
CONECT   18   17   19                                                       
CONECT   19   18   20                                                       
CONECT   20   19   21   22                                                  
CONECT   21   20                                                            
CONECT   22   20                                                            
CONECT   23   17   24                                                       
CONECT   24   23   10   25                                                  
CONECT   25   24                                                            
MASTER        0    0    0    0    0    0    0    0   25    0   50    0
END

View in JSmol

Synonyms

Value	Source
Islandate I	Generator

Chemical Formula

C₁₇H₁₈O₈

Average Mass

350.3230 Da

Monoisotopic Mass

350.10017 Da

IUPAC Name

(2E)-3-(3-{[(2E,4E)-hexa-2,4-dienoyloxy]methyl}-5-(hydroxymethyl)-4-methoxy-2-oxo-2H-pyran-6-yl)prop-2-enoic acid

Traditional Name

(2E)-3-(5-{[(2E,4E)-hexa-2,4-dienoyloxy]methyl}-3-(hydroxymethyl)-4-methoxy-6-oxopyran-2-yl)prop-2-enoic acid

CAS Registry Number

Not Available

SMILES

COC1=C(COC(=O)\C=C\C=C\C)C(=O)OC(\C=C\C(O)=O)=C1CO

InChI Identifier

InChI=1S/C17H18O8/c1-3-4-5-6-15(21)24-10-12-16(23-2)11(9-18)13(25-17(12)22)7-8-14(19)20/h3-8,18H,9-10H2,1-2H3,(H,19,20)/b4-3+,6-5+,8-7+

InChI Key

OUBRQRPPZKZTIX-ARQDATDDSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Talaromyces islandicus	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as pyranones and derivatives. Pyranones and derivatives are compounds containing a pyran ring which bears a ketone.

Kingdom

Organic compounds

Super Class

Organoheterocyclic compounds

Class

Pyrans

Sub Class

Pyranones and derivatives

Direct Parent

Pyranones and derivatives

Alternative Parents

Substituents

Alkyl aryl ether
Fatty acid ester
Pyranone
Dicarboxylic acid or derivatives
Fatty acyl
Heteroaromatic compound
Vinylogous ester
Alpha,beta-unsaturated carboxylic ester
Enoate ester
Carboxylic acid ester
Lactone
Carboxylic acid derivative
Carboxylic acid
Ether
Oxacycle
Hydrocarbon derivative
Organic oxygen compound
Organic oxide
Alcohol
Carbonyl group
Aromatic alcohol
Organooxygen compound
Primary alcohol
Aromatic heteromonocyclic compound

Molecular Framework

Aromatic heteromonocyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	0.88	ChemAxon
pKa (Strongest Acidic)	4.03	ChemAxon
pKa (Strongest Basic)	-2.8	ChemAxon
Physiological Charge	-1	ChemAxon
Hydrogen Acceptor Count	6	ChemAxon
Hydrogen Donor Count	2	ChemAxon
Polar Surface Area	119.36 Å²	ChemAxon
Rotatable Bond Count	9	ChemAxon
Refractivity	92.27 m³·mol⁻¹	ChemAxon
Polarizability	35.25 Å³	ChemAxon
Number of Rings	1	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

13175188

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for (2e)-3-(5-{[(2e,4e)-hexa-2,4-dienoyloxy]methyl}-3-(hydroxymethyl)-4-methoxy-6-oxopyran-2-yl)prop-2-enoic acid (NP0306380)

MOL for NP0306380 ((2e)-3-(5-{[(2e,4e)-hexa-2,4-dienoyloxy]methyl}-3-(hydroxymethyl)-4-methoxy-6-oxopyran-2-yl)prop-2-enoic acid)

3D MOL for NP0306380 ((2e)-3-(5-{[(2e,4e)-hexa-2,4-dienoyloxy]methyl}-3-(hydroxymethyl)-4-methoxy-6-oxopyran-2-yl)prop-2-enoic acid)

3D SDF for NP0306380 ((2e)-3-(5-{[(2e,4e)-hexa-2,4-dienoyloxy]methyl}-3-(hydroxymethyl)-4-methoxy-6-oxopyran-2-yl)prop-2-enoic acid)

3D-SDF for NP0306380 ((2e)-3-(5-{[(2e,4e)-hexa-2,4-dienoyloxy]methyl}-3-(hydroxymethyl)-4-methoxy-6-oxopyran-2-yl)prop-2-enoic acid)

PDB for NP0306380 ((2e)-3-(5-{[(2e,4e)-hexa-2,4-dienoyloxy]methyl}-3-(hydroxymethyl)-4-methoxy-6-oxopyran-2-yl)prop-2-enoic acid)

3D PDB for NP0306380 ((2e)-3-(5-{[(2e,4e)-hexa-2,4-dienoyloxy]methyl}-3-(hydroxymethyl)-4-methoxy-6-oxopyran-2-yl)prop-2-enoic acid)

SMILES for NP0306380 ((2e)-3-(5-{[(2e,4e)-hexa-2,4-dienoyloxy]methyl}-3-(hydroxymethyl)-4-methoxy-6-oxopyran-2-yl)prop-2-enoic acid)

INCHI for NP0306380 ((2e)-3-(5-{[(2e,4e)-hexa-2,4-dienoyloxy]methyl}-3-(hydroxymethyl)-4-methoxy-6-oxopyran-2-yl)prop-2-enoic acid)

Structure for NP0306380 ((2e)-3-(5-{[(2e,4e)-hexa-2,4-dienoyloxy]methyl}-3-(hydroxymethyl)-4-methoxy-6-oxopyran-2-yl)prop-2-enoic acid)

3D Structure for NP0306380 ((2e)-3-(5-{[(2e,4e)-hexa-2,4-dienoyloxy]methyl}-3-(hydroxymethyl)-4-methoxy-6-oxopyran-2-yl)prop-2-enoic acid)