NP-MRD: Showing NP-Card for (5e,7z,9e,11e,13e,15e,17e,19z,21e,23e)-3-hydroxy-24-methyl-25-oxohexacosa-5,7,9,11,13,15,17,19,21,23-decaenoic acid (NP0297027)

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Record Information

Version

1.0

Created at

2022-09-10 06:59:36 UTC

Updated at

2022-09-10 06:59:36 UTC

NP-MRD ID

NP0297027

Secondary Accession Numbers

None

Natural Product Identification

Common Name

(5e,7z,9e,11e,13e,15e,17e,19z,21e,23e)-3-hydroxy-24-methyl-25-oxohexacosa-5,7,9,11,13,15,17,19,21,23-decaenoic acid

Description

7-Cis-laetiporic acid a, also known as 7-cis-laetipate a, belongs to the class of organic compounds known as very long-chain fatty acids. These are fatty acids with an aliphatic tail that contains at least 22 carbon atoms. (5e,7z,9e,11e,13e,15e,17e,19z,21e,23e)-3-hydroxy-24-methyl-25-oxohexacosa-5,7,9,11,13,15,17,19,21,23-decaenoic acid is found in Laetiporus sulphureus. It was first documented in 2022 (PMID: 36111068). Based on a literature review a significant number of articles have been published on 7-cis-laetiporic acid a (PMID: 36110537) (PMID: 36109723) (PMID: 36109198) (PMID: 36107364).

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652309102208592D          

 31 30  0  0  0  0            999 V2000
  -10.9085    8.5520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  -10.1940    8.1395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  -10.1940    7.3145    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -9.4796    8.5520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -9.4796    9.3770    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -8.7651    8.1395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -8.0506    8.5520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -7.3362    8.1395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.6217    8.5520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.9072    8.1395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.9072    7.3145    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1927    6.9020    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1927    6.0770    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4783    5.6645    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4783    4.8395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7638    4.4270    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7638    3.6020    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0493    3.1895    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0493    2.3645    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3349    1.9520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3349    1.1270    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6204    0.7145    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9059    1.1270    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1914    0.7145    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5230    1.1270    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2375    0.7145    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2375   -0.1105    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.9520    1.1270    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6664    0.7145    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3809    1.1270    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.6664   -0.1105    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  2  0  0  0  0
  2  4  1  0  0  0  0
  4  5  1  0  0  0  0
  4  6  2  0  0  0  0
  6  7  1  0  0  0  0
  7  8  2  0  0  0  0
  8  9  1  0  0  0  0
  9 10  2  0  0  0  0
 10 11  1  0  0  0  0
 11 12  2  0  0  0  0
 12 13  1  0  0  0  0
 13 14  2  0  0  0  0
 14 15  1  0  0  0  0
 15 16  2  0  0  0  0
 16 17  1  0  0  0  0
 17 18  2  0  0  0  0
 18 19  1  0  0  0  0
 19 20  2  0  0  0  0
 20 21  1  0  0  0  0
 21 22  2  0  0  0  0
 22 23  1  0  0  0  0
 23 24  2  0  0  0  0
 24 25  1  0  0  0  0
 25 26  1  0  0  0  0
 26 27  1  0  0  0  0
 26 28  1  0  0  0  0
 28 29  1  0  0  0  0
 29 30  2  0  0  0  0
 29 31  1  0  0  0  0
M  END

     RDKit          3D

 63 62  0  0  0  0  0  0  0  0999 V2000
    4.2016    9.9629   -7.7562 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5815    8.7734   -7.1111 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6955    8.1410   -7.7365 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.0053    8.3732   -5.7930 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0695    9.1417   -5.0690 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4617    7.3069   -5.1838 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9523    6.9854   -3.8629 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4639    5.9311   -3.1759 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9801    5.6399   -1.8544 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5495    4.6412   -1.1417 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5232    3.7478   -1.6171 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1300    2.7645   -0.8385 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1031    1.8362   -1.2670 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6880    0.8471   -0.5000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3461   -0.1099   -0.8975 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7281   -1.0736   -0.0853 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7549   -2.0701   -0.4053 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0880   -3.0019    0.4627 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0881   -4.0258    0.2372 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3806   -4.9355    1.1803 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3695   -5.9619    0.9783 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6536   -6.8433    1.9195 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0085   -6.8558    3.2183 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3576   -7.7769    4.0906 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7604   -7.8848    5.4672 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7553   -6.8070    5.7346 C   0  0  1  0  0  0  0  0  0  0  0  0
   -3.3912   -5.5553    5.6399 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1337   -6.9392    7.0727 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0957   -6.8359    8.1780 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3133   -6.6029    8.0177 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6257   -7.0084    9.4851 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.2016   10.8353   -7.0519 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.5875   10.2395   -8.6395 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.2151    9.7431   -8.1531 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.5741    9.5396   -4.1575 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.8711    8.3890   -4.8239 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.4297    9.9340   -5.7199 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.6989    6.7528   -5.6999 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.7160    7.5582   -3.3648 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.7005    5.3836   -3.7001 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.7705    6.2791   -1.4263 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.9637    4.4432   -0.1348 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.0758    3.8704   -2.5899 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.5749    2.6423    0.1277 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.6694    1.9610   -2.2454 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.1668    0.7718    0.4859 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8293   -0.0631   -1.8569 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2513   -1.1247    0.8758 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2728   -2.0783   -1.3528 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5594   -2.9878    1.4305 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6266   -4.0917   -0.6907 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8073   -4.8168    2.0840 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9379   -6.0709    0.0494 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.4241   -7.6214    1.7359 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2530   -6.1268    3.4564 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1159   -8.5165    3.8339 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2501   -8.8809    5.5002 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5798   -7.8424    6.1842 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9915   -6.8113    4.9075 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7478   -4.8349    5.4301 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6069   -7.9266    7.2103 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3519   -6.1444    7.2205 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1647   -6.2084    9.9437 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  2  0
  2  4  1  0
  4  5  1  0
  4  6  2  0
  6  7  1  0
  7  8  2  0
  8  9  1  0
  9 10  2  0
 10 11  1  0
 11 12  2  0
 12 13  1  0
 13 14  2  0
 14 15  1  0
 15 16  2  0
 16 17  1  0
 17 18  2  0
 18 19  1  0
 19 20  2  0
 20 21  1  0
 21 22  2  0
 22 23  1  0
 23 24  2  0
 24 25  1  0
 25 26  1  0
 26 27  1  0
 26 28  1  0
 28 29  1  0
 29 31  1  0
 29 30  2  0
  1 32  1  0
  1 33  1  0
  1 34  1  0
  5 35  1  0
  5 36  1  0
  5 37  1  0
  6 38  1  0
  7 39  1  0
  8 40  1  0
  9 41  1  0
 10 42  1  0
 11 43  1  0
 12 44  1  0
 13 45  1  0
 14 46  1  0
 15 47  1  0
 16 48  1  0
 17 49  1  0
 18 50  1  0
 19 51  1  0
 20 52  1  0
 21 53  1  0
 22 54  1  0
 23 55  1  0
 24 56  1  0
 25 57  1  0
 25 58  1  0
 26 59  1  6
 27 60  1  0
 28 61  1  0
 28 62  1  0
 31 63  1  0
M  END


  Mrv1652309102208592D          

 31 30  0  0  0  0            999 V2000
  -10.9085    8.5520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  -10.1940    8.1395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  -10.1940    7.3145    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -9.4796    8.5520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -9.4796    9.3770    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -8.7651    8.1395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -8.0506    8.5520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -7.3362    8.1395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.6217    8.5520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.9072    8.1395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.9072    7.3145    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1927    6.9020    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1927    6.0770    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4783    5.6645    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4783    4.8395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7638    4.4270    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7638    3.6020    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0493    3.1895    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0493    2.3645    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3349    1.9520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3349    1.1270    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6204    0.7145    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9059    1.1270    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1914    0.7145    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5230    1.1270    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2375    0.7145    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2375   -0.1105    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.9520    1.1270    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6664    0.7145    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3809    1.1270    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.6664   -0.1105    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  2  0  0  0  0
  2  4  1  0  0  0  0
  4  5  1  0  0  0  0
  4  6  2  0  0  0  0
  6  7  1  0  0  0  0
  7  8  2  0  0  0  0
  8  9  1  0  0  0  0
  9 10  2  0  0  0  0
 10 11  1  0  0  0  0
 11 12  2  0  0  0  0
 12 13  1  0  0  0  0
 13 14  2  0  0  0  0
 14 15  1  0  0  0  0
 15 16  2  0  0  0  0
 16 17  1  0  0  0  0
 17 18  2  0  0  0  0
 18 19  1  0  0  0  0
 19 20  2  0  0  0  0
 20 21  1  0  0  0  0
 21 22  2  0  0  0  0
 22 23  1  0  0  0  0
 23 24  2  0  0  0  0
 24 25  1  0  0  0  0
 25 26  1  0  0  0  0
 26 27  1  0  0  0  0
 26 28  1  0  0  0  0
 28 29  1  0  0  0  0
 29 30  2  0  0  0  0
 29 31  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0297027

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CC(=O)C(\C)=C\C=C\C=C/C=C/C=C/C=C/C=C/C=C/C=C\C=C\CC(O)CC(O)=O

> <INCHI_IDENTIFIER>
InChI=1S/C27H32O4/c1-24(25(2)28)21-19-17-15-13-11-9-7-5-3-4-6-8-10-12-14-16-18-20-22-26(29)23-27(30)31/h3-21,26,29H,22-23H2,1-2H3,(H,30,31)/b4-3+,7-5+,8-6+,11-9+,12-10+,15-13-,16-14-,19-17+,20-18+,24-21+

> <INCHI_KEY>
KTAMMGIWIFDREV-SLHRBXMBSA-N

> <FORMULA>
C27H32O4

> <MOLECULAR_WEIGHT>
420.549

> <EXACT_MASS>
420.23005951

> <JCHEM_ACCEPTOR_COUNT>
4

> <JCHEM_ATOM_COUNT>
63

> <JCHEM_AVERAGE_POLARIZABILITY>
51.142149387666336

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
2

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(5E,7Z,9E,11E,13E,15E,17E,19Z,21E,23E)-3-hydroxy-24-methyl-25-oxohexacosa-5,7,9,11,13,15,17,19,21,23-decaenoic acid

> <JCHEM_LOGP>
5.172352522333333

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
0

> <JCHEM_PHYSIOLOGICAL_CHARGE>
-1

> <JCHEM_PKA>
15.232285749338075

> <JCHEM_PKA_STRONGEST_ACIDIC>
4.579722753082734

> <JCHEM_PKA_STRONGEST_BASIC>
-2.823145651741534

> <JCHEM_POLAR_SURFACE_AREA>
74.6

> <JCHEM_REFRACTIVITY>
140.72440000000006

> <JCHEM_ROTATABLE_BOND_COUNT>
14

> <JCHEM_RULE_OF_FIVE>
0

> <JCHEM_TRADITIONAL_IUPAC>
(5E,7Z,9E,11E,13E,15E,17E,19Z,21E,23E)-3-hydroxy-24-methyl-25-oxohexacosa-5,7,9,11,13,15,17,19,21,23-decaenoic acid

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 10-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   10-SEP-22         0                                  
HETATM    1  C   UNK     0     -20.363  15.964   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0     -19.029  15.194   0.000  0.00  0.00           C+0
HETATM    3  O   UNK     0     -19.029  13.654   0.000  0.00  0.00           O+0
HETATM    4  C   UNK     0     -17.695  15.964   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0     -17.695  17.504   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0     -16.362  15.194   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0     -15.028  15.964   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0     -13.694  15.194   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0     -12.360  15.964   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0     -11.027  15.194   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0     -11.027  13.654   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0      -9.693  12.884   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0      -9.693  11.344   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0      -8.359  10.574   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0      -8.359   9.034   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0      -7.026   8.264   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0      -7.026   6.724   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0      -5.692   5.954   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0      -5.692   4.414   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0      -4.358   3.644   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0      -4.358   2.104   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0      -3.025   1.334   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0      -1.691   2.104   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0      -0.357   1.334   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0       0.976   2.104   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0       2.310   1.334   0.000  0.00  0.00           C+0
HETATM   27  O   UNK     0       2.310  -0.206   0.000  0.00  0.00           O+0
HETATM   28  C   UNK     0       3.644   2.104   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0       4.977   1.334   0.000  0.00  0.00           C+0
HETATM   30  O   UNK     0       6.311   2.104   0.000  0.00  0.00           O+0
HETATM   31  O   UNK     0       4.977  -0.206   0.000  0.00  0.00           O+0
CONECT    1    2                                                            
CONECT    2    1    3    4                                                  
CONECT    3    2                                                            
CONECT    4    2    5    6                                                  
CONECT    5    4                                                            
CONECT    6    4    7                                                       
CONECT    7    6    8                                                       
CONECT    8    7    9                                                       
CONECT    9    8   10                                                       
CONECT   10    9   11                                                       
CONECT   11   10   12                                                       
CONECT   12   11   13                                                       
CONECT   13   12   14                                                       
CONECT   14   13   15                                                       
CONECT   15   14   16                                                       
CONECT   16   15   17                                                       
CONECT   17   16   18                                                       
CONECT   18   17   19                                                       
CONECT   19   18   20                                                       
CONECT   20   19   21                                                       
CONECT   21   20   22                                                       
CONECT   22   21   23                                                       
CONECT   23   22   24                                                       
CONECT   24   23   25                                                       
CONECT   25   24   26                                                       
CONECT   26   25   27   28                                                  
CONECT   27   26                                                            
CONECT   28   26   29                                                       
CONECT   29   28   30   31                                                  
CONECT   30   29                                                            
CONECT   31   29                                                            
MASTER        0    0    0    0    0    0    0    0   31    0   60    0
END

View in JSmol

Synonyms

Value	Source
7-cis-Laetipate a	Generator
7-cis-Laetipic acid a	Generator

Chemical Formula

C₂₇H₃₂O₄

Average Mass

420.5490 Da

Monoisotopic Mass

420.23006 Da

IUPAC Name

(5E,7Z,9E,11E,13E,15E,17E,19Z,21E,23E)-3-hydroxy-24-methyl-25-oxohexacosa-5,7,9,11,13,15,17,19,21,23-decaenoic acid

Traditional Name

(5E,7Z,9E,11E,13E,15E,17E,19Z,21E,23E)-3-hydroxy-24-methyl-25-oxohexacosa-5,7,9,11,13,15,17,19,21,23-decaenoic acid

CAS Registry Number

Not Available

SMILES

CC(=O)C(\C)=C\C=C\C=C/C=C/C=C/C=C/C=C/C=C/C=C\C=C\CC(O)CC(O)=O

InChI Identifier

InChI=1S/C27H32O4/c1-24(25(2)28)21-19-17-15-13-11-9-7-5-3-4-6-8-10-12-14-16-18-20-22-26(29)23-27(30)31/h3-21,26,29H,22-23H2,1-2H3,(H,30,31)/b4-3+,7-5+,8-6+,11-9+,12-10+,15-13-,16-14-,19-17+,20-18+,24-21+

InChI Key

KTAMMGIWIFDREV-SLHRBXMBSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Laetiporus sulphureus	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as very long-chain fatty acids. These are fatty acids with an aliphatic tail that contains at least 22 carbon atoms.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Fatty Acyls

Sub Class

Fatty acids and conjugates

Direct Parent

Very long-chain fatty acids

Alternative Parents

Substituents

Very long-chain fatty acid
Beta-hydroxy acid
Branched fatty acid
Hydroxy fatty acid
Alpha-branched alpha,beta-unsaturated-ketone
Unsaturated fatty acid
Hydroxy acid
Acryloyl-group
Alpha,beta-unsaturated ketone
Enone
Secondary alcohol
Ketone
Carboxylic acid
Carboxylic acid derivative
Monocarboxylic acid or derivatives
Organooxygen compound
Organic oxygen compound
Carbonyl group
Hydrocarbon derivative
Organic oxide
Alcohol
Aliphatic acyclic compound

Molecular Framework

Aliphatic acyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	5.17	ChemAxon
pKa (Strongest Acidic)	4.58	ChemAxon
pKa (Strongest Basic)	-2.8	ChemAxon
Physiological Charge	-1	ChemAxon
Hydrogen Acceptor Count	4	ChemAxon
Hydrogen Donor Count	2	ChemAxon
Polar Surface Area	74.6 Å²	ChemAxon
Rotatable Bond Count	14	ChemAxon
Refractivity	140.72 m³·mol⁻¹	ChemAxon
Polarizability	51.14 Å³	ChemAxon
Number of Rings	0	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

78434764

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

102356186

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

Goodrich JA, Walker D, Lin X, Wang H, Lim T, McConnell R, Conti DV, Chatzi L, Setiawan VW: Exposure to perfluoroalkyl substances and risk of hepatocellular carcinoma in a multiethnic cohort. JHEP Rep. 2022 Aug 8;4(10):100550. doi: 10.1016/j.jhepr.2022.100550. eCollection 2022 Oct. [PubMed:36111068 ]
Guoyun X, Dawei D, Ning L, Yinan H, Fangfang Y, Siyuan T, Hao S, Jiaqi Y, Ang X, Guanya G, Xi C, Yulong S, Ying H: Efficacy and safety of fenofibrate add-on therapy in patients with primary biliary cholangitis refractory to ursodeoxycholic acid: A retrospective study and updated meta-analysis. Front Pharmacol. 2022 Aug 30;13:948362. doi: 10.3389/fphar.2022.948362. eCollection 2022. [PubMed:36110537 ]
Ma S, Xu Q, Hu Q, Huang L, Wu D, Lin G, Chen X, Luo W: Post-operative uric acid: a predictor for 30-days mortality of acute type A aortic dissection repair. BMC Cardiovasc Disord. 2022 Sep 15;22(1):411. doi: 10.1186/s12872-022-02749-9. [PubMed:36109723 ]
Hu Z, Zhu Y, Chen J, Chen J, Li C, Gao Z, Li J, Liu L: Sesquiterpenoids with Phytotoxic and Antifungal Activities from a Pathogenic Fungus Aspergillus alabamensis. J Agric Food Chem. 2022 Sep 28;70(38):12065-12073. doi: 10.1021/acs.jafc.2c05703. Epub 2022 Sep 15. [PubMed:36109198 ]
Liu S, Lin H, Chen Y, Wang Y, Zhang X, Xiang Z, Cai X: Metabolic Profiling of Glabridin in Rat Plasma, Urine, Bile, and Feces After Intragastric and Intravenous Administration. Eur J Drug Metab Pharmacokinet. 2022 Nov;47(6):879-887. doi: 10.1007/s13318-022-00797-2. Epub 2022 Sep 15. [PubMed:36107364 ]
LOTUS database [Link]

Showing NP-Card for (5e,7z,9e,11e,13e,15e,17e,19z,21e,23e)-3-hydroxy-24-methyl-25-oxohexacosa-5,7,9,11,13,15,17,19,21,23-decaenoic acid (NP0297027)

MOL for NP0297027 ((5e,7z,9e,11e,13e,15e,17e,19z,21e,23e)-3-hydroxy-24-methyl-25-oxohexacosa-5,7,9,11,13,15,17,19,21,23-decaenoic acid)

3D MOL for NP0297027 ((5e,7z,9e,11e,13e,15e,17e,19z,21e,23e)-3-hydroxy-24-methyl-25-oxohexacosa-5,7,9,11,13,15,17,19,21,23-decaenoic acid)

3D SDF for NP0297027 ((5e,7z,9e,11e,13e,15e,17e,19z,21e,23e)-3-hydroxy-24-methyl-25-oxohexacosa-5,7,9,11,13,15,17,19,21,23-decaenoic acid)

3D-SDF for NP0297027 ((5e,7z,9e,11e,13e,15e,17e,19z,21e,23e)-3-hydroxy-24-methyl-25-oxohexacosa-5,7,9,11,13,15,17,19,21,23-decaenoic acid)

PDB for NP0297027 ((5e,7z,9e,11e,13e,15e,17e,19z,21e,23e)-3-hydroxy-24-methyl-25-oxohexacosa-5,7,9,11,13,15,17,19,21,23-decaenoic acid)

3D PDB for NP0297027 ((5e,7z,9e,11e,13e,15e,17e,19z,21e,23e)-3-hydroxy-24-methyl-25-oxohexacosa-5,7,9,11,13,15,17,19,21,23-decaenoic acid)

SMILES for NP0297027 ((5e,7z,9e,11e,13e,15e,17e,19z,21e,23e)-3-hydroxy-24-methyl-25-oxohexacosa-5,7,9,11,13,15,17,19,21,23-decaenoic acid)

INCHI for NP0297027 ((5e,7z,9e,11e,13e,15e,17e,19z,21e,23e)-3-hydroxy-24-methyl-25-oxohexacosa-5,7,9,11,13,15,17,19,21,23-decaenoic acid)

Structure for NP0297027 ((5e,7z,9e,11e,13e,15e,17e,19z,21e,23e)-3-hydroxy-24-methyl-25-oxohexacosa-5,7,9,11,13,15,17,19,21,23-decaenoic acid)

3D Structure for NP0297027 ((5e,7z,9e,11e,13e,15e,17e,19z,21e,23e)-3-hydroxy-24-methyl-25-oxohexacosa-5,7,9,11,13,15,17,19,21,23-decaenoic acid)