NP-MRD: Showing NP-Card for 7-[(3,7-dimethylocta-2,6-dien-1-yl)oxy]-5-hydroxy-3-(4-methoxyphenyl)chromen-4-one (NP0292146)

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Record Information

Version

2.0

Created at

2022-09-09 23:32:51 UTC

Updated at

2022-09-09 23:32:51 UTC

NP-MRD ID

NP0292146

Secondary Accession Numbers

None

Natural Product Identification

Common Name

7-[(3,7-dimethylocta-2,6-dien-1-yl)oxy]-5-hydroxy-3-(4-methoxyphenyl)chromen-4-one

Description

7-[(3,7-Dimethylocta-2,6-dien-1-yl)oxy]-5-hydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one belongs to the class of organic compounds known as 4'-o-methylisoflavones. These are isoflavones with methoxy groups attached to the C4' atom of the isoflavone backbone. 7-[(3,7-dimethylocta-2,6-dien-1-yl)oxy]-5-hydroxy-3-(4-methoxyphenyl)chromen-4-one is found in Tephrosia tinctoria. 7-[(3,7-Dimethylocta-2,6-dien-1-yl)oxy]-5-hydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one is an extremely weak basic (essentially neutral) compound (based on its pKa).

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1533004161515532D          

 31 33  0  0  0  0            999 V2000
   -2.1434   -3.7125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1434   -2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -2.8875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.0000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868   -0.0000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4302   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4302   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.1447   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.8592   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.5737   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.2881   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.0026   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.2881   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -2.4750    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -2.4750    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  4  5  1  0  0  0  0
  5  6  2  0  0  0  0
  6  7  1  0  0  0  0
  7  8  2  0  0  0  0
  3  8  1  0  0  0  0
  6  9  1  0  0  0  0
  9 10  2  0  0  0  0
 10 11  1  0  0  0  0
 11 12  1  0  0  0  0
 12 13  2  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 17 16  1  4  0  0  0
 17 18  2  0  0  0  0
 18 19  1  0  0  0  0
 18 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  2  0  0  0  0
 23 24  1  0  0  0  0
 23 25  1  0  0  0  0
 14 26  2  0  0  0  0
 26 27  1  0  0  0  0
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 27 29  2  0  0  0  0
 12 29  1  0  0  0  0
 29 30  1  0  0  0  0
  9 30  1  0  0  0  0
 30 31  2  0  0  0  0
M  END

     RDKit          3D

 59 61  0  0  0  0  0  0  0  0999 V2000
   10.4411    1.7731    0.8223 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.9583    1.0723   -0.3107 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.5859    0.8580   -0.3991 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.7073    1.3015    0.5676 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.3585    1.0985    0.4941 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.8091    0.4165   -0.5919 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3799    0.1865   -0.6958 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.7462    0.4089   -1.8947 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4461    0.1919   -1.9617 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.7581   -0.2276   -0.9147 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3822   -0.4422   -1.0388 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3827   -0.8785    0.0181 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7466   -1.0993   -0.0763 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4274   -0.8833   -1.2825 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8498   -1.1830   -1.1346 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3832   -1.5967   -0.0084 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6035   -1.8089    1.2481 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.8755   -1.8659   -0.0129 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.5616   -0.9750    1.0009 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.2921    0.4372    0.6136 C   0  0  0  0  0  0  0  0  0  0  0  0
   -7.2739    1.2712    0.3278 C   0  0  0  0  0  0  0  0  0  0  0  0
   -8.6763    0.7835    0.3963 C   0  0  0  0  0  0  0  0  0  0  0  0
   -7.0074    2.6724   -0.0565 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1978   -1.1216    1.2560 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5665   -0.9072    1.3766 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2140   -1.1295    2.5838 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.3209   -0.4718    0.3158 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6996   -0.2503    0.4174 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2177   -0.4690    1.5283 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.6895   -0.0249   -1.5550 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.0505    0.1805   -1.4800 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.0731    2.8243    0.7073 H   0  0  0  0  0  0  0  0  0  0  0  0
   11.5466    1.7367    0.8237 H   0  0  0  0  0  0  0  0  0  0  0  0
   10.0306    1.2905    1.7387 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.0848    1.8453    1.4460 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.6512    1.4393    1.2437 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.3103    0.7508   -2.7458 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0815   -0.2602   -1.9846 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9500   -1.5553   -2.0597 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2421    0.1546   -1.6785 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5347   -1.0629   -2.0027 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8672   -2.6277    1.1796 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3484   -2.1778    2.0188 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2188   -0.8546    1.6412 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.2644   -1.6744   -1.0147 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.9842   -2.9206    0.2505 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.6300   -1.1975    1.0513 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1270   -1.1707    1.9991 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.2635    0.7754    0.5690 H   0  0  0  0  0  0  0  0  0  0  0  0
   -8.7724   -0.0072   -0.3823 H   0  0  0  0  0  0  0  0  0  0  0  0
   -9.3838    1.5840    0.1306 H   0  0  0  0  0  0  0  0  0  0  0  0
   -8.8824    0.3761    1.4087 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.0872    3.3556    0.8105 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.0221    2.7093   -0.5570 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.7947    2.9917   -0.7800 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3882   -1.4638    2.0943 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.6837   -1.4533    3.3921 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.2650   -0.5613   -2.4106 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.7479   -0.1638   -2.2336 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  2  0
  4  5  1  0
  5  6  2  0
  6 30  1  0
 30 31  2  0
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 13 14  1  0
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 20 21  2  3
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 25 26  1  0
 25 27  2  0
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 31  3  1  0
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 27 10  1  0
  1 32  1  0
  1 33  1  0
  1 34  1  0
  4 35  1  0
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 30 58  1  0
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 22 52  1  0
 23 53  1  0
 23 54  1  0
 23 55  1  0
 24 56  1  0
 26 57  1  0
M  END


  Mrv1533004161515532D          

 31 33  0  0  0  0            999 V2000
   -2.1434   -3.7125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1434   -2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -2.8875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.0000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868   -0.0000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
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    6.4302   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.1447   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.8592   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.5737   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.2881   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
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    3.5724   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -2.4750    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
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    1.4289   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -2.4750    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  4  5  1  0  0  0  0
  5  6  2  0  0  0  0
  6  7  1  0  0  0  0
  7  8  2  0  0  0  0
  3  8  1  0  0  0  0
  6  9  1  0  0  0  0
  9 10  2  0  0  0  0
 10 11  1  0  0  0  0
 11 12  1  0  0  0  0
 12 13  2  0  0  0  0
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 18 20  1  0  0  0  0
 20 21  1  0  0  0  0
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 22 23  2  0  0  0  0
 23 24  1  0  0  0  0
 23 25  1  0  0  0  0
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 30 31  2  0  0  0  0
M  END
> <DATABASE_ID>
NP0292146

> <DATABASE_NAME>
NP-MRD

> <SMILES>
COC1=CC=C(C=C1)C1=COC2=CC(OCC=C(C)CCC=C(C)C)=CC(O)=C2C1=O

> <INCHI_IDENTIFIER>
InChI=1S/C26H28O5/c1-17(2)6-5-7-18(3)12-13-30-21-14-23(27)25-24(15-21)31-16-22(26(25)28)19-8-10-20(29-4)11-9-19/h6,8-12,14-16,27H,5,7,13H2,1-4H3

> <INCHI_KEY>
BCMWIEXPSAVRQD-UHFFFAOYSA-N

> <FORMULA>
C26H28O5

> <MOLECULAR_WEIGHT>
420.505

> <EXACT_MASS>
420.193674002

> <JCHEM_ACCEPTOR_COUNT>
5

> <JCHEM_ATOM_COUNT>
59

> <JCHEM_AVERAGE_POLARIZABILITY>
48.22536665040502

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
1

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
7-[(3,7-dimethylocta-2,6-dien-1-yl)oxy]-5-hydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one

> <ALOGPS_LOGP>
4.94

> <JCHEM_LOGP>
6.389620866333333

> <ALOGPS_LOGS>
-5.44

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
3

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA_STRONGEST_ACIDIC>
7.3231609503943655

> <JCHEM_PKA_STRONGEST_BASIC>
-4.495605058488145

> <JCHEM_POLAR_SURFACE_AREA>
64.99000000000001

> <JCHEM_REFRACTIVITY>
123.56829999999998

> <JCHEM_ROTATABLE_BOND_COUNT>
8

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
1.52e-03 g/l

> <JCHEM_TRADITIONAL_IUPAC>
7-[(3,7-dimethylocta-2,6-dien-1-yl)oxy]-5-hydroxy-3-(4-methoxyphenyl)chromen-4-one

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 16-APR-15   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   16-APR-15         0                                  
HETATM    1  C   UNK     0      -4.001  -6.930   0.000  0.00  0.00           C+0
HETATM    2  O   UNK     0      -4.001  -5.390   0.000  0.00  0.00           O+0
HETATM    3  C   UNK     0      -2.667  -4.620   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      -2.667  -3.080   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      -1.334  -2.310   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       0.000  -3.080   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       0.000  -4.620   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0      -1.334  -5.390   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       1.334  -2.310   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       1.334  -0.770   0.000  0.00  0.00           C+0
HETATM   11  O   UNK     0       2.667   0.000   0.000  0.00  0.00           O+0
HETATM   12  C   UNK     0       4.001  -0.770   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       5.335   0.000   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       6.668  -0.770   0.000  0.00  0.00           C+0
HETATM   15  O   UNK     0       8.002  -0.000   0.000  0.00  0.00           O+0
HETATM   16  C   UNK     0       9.336  -0.770   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0      10.669  -0.000   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0      12.003  -0.770   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0      12.003  -2.310   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0      13.337  -0.000   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0      14.670  -0.770   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0      16.004  -0.000   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0      17.338  -0.770   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0      18.672  -0.000   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0      17.338  -2.310   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0       6.668  -2.310   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0       5.335  -3.080   0.000  0.00  0.00           C+0
HETATM   28  O   UNK     0       5.335  -4.620   0.000  0.00  0.00           O+0
HETATM   29  C   UNK     0       4.001  -2.310   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0       2.667  -3.080   0.000  0.00  0.00           C+0
HETATM   31  O   UNK     0       2.667  -4.620   0.000  0.00  0.00           O+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4    8                                                  
CONECT    4    3    5                                                       
CONECT    5    4    6                                                       
CONECT    6    5    7    9                                                  
CONECT    7    6    8                                                       
CONECT    8    7    3                                                       
CONECT    9    6   10   30                                                  
CONECT   10    9   11                                                       
CONECT   11   10   12                                                       
CONECT   12   11   13   29                                                  
CONECT   13   12   14                                                       
CONECT   14   13   15   26                                                  
CONECT   15   14   16                                                       
CONECT   16   15   17                                                       
CONECT   17   16   18                                                       
CONECT   18   17   19   20                                                  
CONECT   19   18                                                            
CONECT   20   18   21                                                       
CONECT   21   20   22                                                       
CONECT   22   21   23                                                       
CONECT   23   22   24   25                                                  
CONECT   24   23                                                            
CONECT   25   23                                                            
CONECT   26   14   27                                                       
CONECT   27   26   28   29                                                  
CONECT   28   27                                                            
CONECT   29   27   12   30                                                  
CONECT   30   29    9   31                                                  
CONECT   31   30                                                            
MASTER        0    0    0    0    0    0    0    0   31    0   66    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₂₆H₂₈O₅

Average Mass

420.5050 Da

Monoisotopic Mass

420.19367 Da

IUPAC Name

7-[(3,7-dimethylocta-2,6-dien-1-yl)oxy]-5-hydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one

Traditional Name

7-[(3,7-dimethylocta-2,6-dien-1-yl)oxy]-5-hydroxy-3-(4-methoxyphenyl)chromen-4-one

CAS Registry Number

Not Available

SMILES

COC1=CC=C(C=C1)C1=COC2=CC(OCC=C(C)CCC=C(C)C)=CC(O)=C2C1=O

InChI Identifier

InChI=1S/C26H28O5/c1-17(2)6-5-7-18(3)12-13-30-21-14-23(27)25-24(15-21)31-16-22(26(25)28)19-8-10-20(29-4)11-9-19/h6,8-12,14-16,27H,5,7,13H2,1-4H3

InChI Key

BCMWIEXPSAVRQD-UHFFFAOYSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Tephrosia tinctoria	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as 4'-o-methylisoflavones. These are isoflavones with methoxy groups attached to the C4' atom of the isoflavone backbone.

Kingdom

Organic compounds

Super Class

Phenylpropanoids and polyketides

Class

Isoflavonoids

Sub Class

O-methylated isoflavonoids

Direct Parent

4'-O-methylisoflavones

Alternative Parents

Substituents

4p-o-methylisoflavone
Isoflavone
Hydroxyisoflavonoid
Chromone
Monoterpenoid
1-benzopyran
Bicyclic monoterpenoid
Benzopyran
Aromatic monoterpenoid
Methoxybenzene
Phenol ether
Phenoxy compound
Anisole
1-hydroxy-4-unsubstituted benzenoid
Pyranone
1-hydroxy-2-unsubstituted benzenoid
Alkyl aryl ether
Monocyclic benzene moiety
Benzenoid
Pyran
Vinylogous acid
Heteroaromatic compound
Ether
Organoheterocyclic compound
Oxacycle
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	4.94	ALOGPS
logP	6.39	ChemAxon
logS	-5.4	ALOGPS
pKa (Strongest Acidic)	7.32	ChemAxon
pKa (Strongest Basic)	-4.5	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	5	ChemAxon
Hydrogen Donor Count	1	ChemAxon
Polar Surface Area	64.99 Å²	ChemAxon
Rotatable Bond Count	8	ChemAxon
Refractivity	123.57 m³·mol⁻¹	ChemAxon
Polarizability	48.23 Å³	ChemAxon
Number of Rings	3	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	Yes	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

Not Available

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for 7-[(3,7-dimethylocta-2,6-dien-1-yl)oxy]-5-hydroxy-3-(4-methoxyphenyl)chromen-4-one (NP0292146)

MOL for NP0292146 (7-[(3,7-dimethylocta-2,6-dien-1-yl)oxy]-5-hydroxy-3-(4-methoxyphenyl)chromen-4-one)

3D MOL for NP0292146 (7-[(3,7-dimethylocta-2,6-dien-1-yl)oxy]-5-hydroxy-3-(4-methoxyphenyl)chromen-4-one)

3D SDF for NP0292146 (7-[(3,7-dimethylocta-2,6-dien-1-yl)oxy]-5-hydroxy-3-(4-methoxyphenyl)chromen-4-one)

3D-SDF for NP0292146 (7-[(3,7-dimethylocta-2,6-dien-1-yl)oxy]-5-hydroxy-3-(4-methoxyphenyl)chromen-4-one)

PDB for NP0292146 (7-[(3,7-dimethylocta-2,6-dien-1-yl)oxy]-5-hydroxy-3-(4-methoxyphenyl)chromen-4-one)

3D PDB for NP0292146 (7-[(3,7-dimethylocta-2,6-dien-1-yl)oxy]-5-hydroxy-3-(4-methoxyphenyl)chromen-4-one)

SMILES for NP0292146 (7-[(3,7-dimethylocta-2,6-dien-1-yl)oxy]-5-hydroxy-3-(4-methoxyphenyl)chromen-4-one)

INCHI for NP0292146 (7-[(3,7-dimethylocta-2,6-dien-1-yl)oxy]-5-hydroxy-3-(4-methoxyphenyl)chromen-4-one)

Structure for NP0292146 (7-[(3,7-dimethylocta-2,6-dien-1-yl)oxy]-5-hydroxy-3-(4-methoxyphenyl)chromen-4-one)

3D Structure for NP0292146 (7-[(3,7-dimethylocta-2,6-dien-1-yl)oxy]-5-hydroxy-3-(4-methoxyphenyl)chromen-4-one)