NP-MRD: Showing NP-Card for 3-(acetyloxy)-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4a,5,6,7,8,9,10,11,12,12a,14a-tetradecahydropicene-4-carboxylic acid (NP0290233)

Jump To Section:

Identification Spectra BioTaxonomy ChemoTaxonomy Physical properties Links References XML

Record Information

Version

2.0

Created at

2022-09-09 20:49:32 UTC

Updated at

2022-09-09 20:49:33 UTC

NP-MRD ID

NP0290233

Secondary Accession Numbers

None

Natural Product Identification

Common Name

3-(acetyloxy)-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4a,5,6,7,8,9,10,11,12,12a,14a-tetradecahydropicene-4-carboxylic acid

Description

AKBA, also known as akba CPD or ackba, belongs to the class of organic compounds known as triterpenoids. These are terpene molecules containing six isoprene units. 3-(acetyloxy)-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4a,5,6,7,8,9,10,11,12,12a,14a-tetradecahydropicene-4-carboxylic acid is found in Boswellia papyrifera, Boswellia sacra and Boswellia serrata. AKBA is an extremely weak basic (essentially neutral) compound (based on its pKa).

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1533004161523412D          

 37 41  0  0  0  0            999 V2000
   -0.1105   -3.1086    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3020   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1105   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3020   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1270   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5395   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3645   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7770   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1895   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3645   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7770   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6020   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0145   -3.1086    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.0145   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.8395   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4270   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2520   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0770   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4895   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.3145   -4.5375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.7270   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.3145   -3.1086    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.5520   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0770   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9337   -6.0644    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2520   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.8395   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0145   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6020   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6882   -6.0725    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.8522   -5.5341    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.4842   -5.0038    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.9955   -6.3466    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.5395   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1270   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5395   -3.1086    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  1  0  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  5  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  1  0  0  0  0
  9 11  1  0  0  0  0
 11 12  2  0  0  0  0
 12 13  1  0  0  0  0
 13 14  2  0  0  0  0
 13 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 16 18  1  0  0  0  0
 18 19  1  0  0  0  0
 19 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  2  0  0  0  0
 22 24  1  0  0  0  0
 20 25  1  0  0  0  0
 25 26  1  0  0  0  0
 25 27  1  0  0  0  0
 16 27  1  0  0  0  0
 27 28  1  0  0  0  0
 28 29  1  0  0  0  0
 29 30  1  0  0  0  0
  9 30  1  0  0  0  0
 15 30  1  0  0  0  0
 30 31  1  0  0  0  0
 25 32  1  0  0  0  0
 32 33  2  0  0  0  0
 32 34  1  0  0  0  0
 11 35  1  0  0  0  0
  5 35  1  0  0  0  0
 35 36  1  0  0  0  0
  2 36  1  0  0  0  0
 36 37  1  0  0  0  0
M  END

     RDKit          3D

 85 89  0  0  0  0  0  0  0  0999 V2000
    7.9437   -1.9159    1.6412 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.0904   -1.0437    0.7910 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.5891   -0.4090   -0.1997 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.7475   -0.8705    1.0121 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.8958   -0.0416    0.2178 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.3706    1.0063    1.1663 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2849    1.8731    0.6239 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3053    1.1125   -0.2540 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.7307    1.4721   -1.6671 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8819    1.5311   -0.0807 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.0672    1.4626   -1.3266 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3588    2.0310   -2.4090 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1961    0.6882   -1.3779 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9519    0.5780   -0.2970 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2033   -0.1208   -0.1579 C   0  0  2  0  0  0  0  0  0  0  0  0
   -3.7769   -0.7362   -1.3748 C   0  0  1  0  0  0  0  0  0  0  0  0
   -3.1983   -2.1508   -1.5065 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.2699   -0.8208   -1.4486 C   0  0  1  0  0  0  0  0  0  0  0  0
   -5.6226   -2.1139   -2.1996 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.0052   -0.8180   -0.1777 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3460   -0.1827    0.9777 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1864    0.7546    0.6136 C   0  0  2  0  0  0  0  0  0  0  0  0
   -4.6796    1.9056   -0.2121 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5963    1.1695    1.9242 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1419    0.9356    2.0835 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3489    1.3083    0.8663 C   0  0  2  0  0  0  0  0  0  0  0  0
   -1.4066    2.7854    0.6910 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0950    0.7723    0.9626 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.4440    1.0817    2.3812 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1766   -0.6854    0.6247 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2981   -1.0947   -0.2823 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5134   -0.3328    0.0803 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.8156   -0.9191   -0.3517 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.8627   -2.3047    0.3425 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9552   -1.2278   -1.7687 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.9305   -0.8504   -2.4620 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.9727   -1.9729   -2.3917 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.9141   -1.3855    1.8435 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.1082   -2.9120    1.1923 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.4584   -2.0537    2.6232 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.5799    0.3817   -0.5597 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.2622    1.6547    1.4178 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.1162    0.5215    2.1437 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.8068    2.7039    0.0580 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.8099    2.4122    1.4580 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.3445    0.8360   -2.4449 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.4804    2.5718   -1.7686 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.8599    1.5358   -1.7343 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.9273    2.6346    0.1649 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5451    0.1939   -2.2653 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0640   -0.9586    0.5952 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4830   -0.2658   -2.3428 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4801   -2.6088   -2.4772 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4446   -2.7705   -0.6418 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0966   -2.0241   -1.5390 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.7027   -0.0070   -2.1044 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.2923   -3.0080   -1.6309 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.2994   -2.0898   -3.2395 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.7506   -2.1525   -2.1599 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.0163   -0.3227   -0.3017 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.2869   -1.8699    0.1346 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9229   -0.9533    1.6782 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.0382    0.4283    1.5930 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.7494    1.7262   -0.4456 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0963    2.0536   -1.1305 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6676    2.8725    0.3638 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0774    0.6642    2.8189 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9143    2.2431    2.0841 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0181   -0.1596    2.3356 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7934    1.5836    2.9231 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6480    3.3619    1.2118 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4354    3.1400   -0.3597 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3884    3.1532    1.1157 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.4490    0.9418    2.7247 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.1450    2.1225    2.6168 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1719    0.3619    3.0009 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.3537   -1.2197    1.6039 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7265   -1.1280    0.2136 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.4788   -2.1935   -0.0819 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.1126   -1.0257   -1.3478 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.5883   -0.4470    1.2086 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.9372   -2.5815    0.3814 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.3375   -3.0347   -0.2725 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.4782   -2.2200    1.3758 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.1613   -2.5632   -3.1901 H   0  0  0  0  0  0  0  0  0  0  0  0
 19 18  1  0
 18 20  1  0
 20 21  1  0
 21 22  1  0
 22 23  1  6
 22 24  1  0
 24 25  1  0
 25 26  1  0
 26 27  1  6
 26 14  1  0
 14 13  2  0
 13 11  1  0
 11 12  2  0
 11 10  1  0
 10  8  1  0
  8  9  1  6
  8  7  1  0
  7  6  1  0
  6  5  1  0
  5  4  1  0
  4  2  1  0
  2  1  1  0
  2  3  2  0
  5 33  1  0
 33 34  1  0
 33 32  1  0
 32 31  1  0
 31 30  1  0
 30 28  1  0
 28 29  1  1
 33 35  1  6
 35 37  1  0
 35 36  2  0
 14 15  1  0
 15 16  1  0
 16 17  1  0
 16 18  1  0
 15 22  1  0
 28 26  1  0
 28 10  1  0
 32  8  1  0
 19 57  1  0
 19 58  1  0
 19 59  1  0
 18 56  1  6
 20 60  1  0
 20 61  1  0
 21 62  1  0
 21 63  1  0
 23 64  1  0
 23 65  1  0
 23 66  1  0
 24 67  1  0
 24 68  1  0
 25 69  1  0
 25 70  1  0
 27 71  1  0
 27 72  1  0
 27 73  1  0
 13 50  1  0
 10 49  1  1
  9 46  1  0
  9 47  1  0
  9 48  1  0
  7 44  1  0
  7 45  1  0
  6 42  1  0
  6 43  1  0
  5 41  1  6
  1 38  1  0
  1 39  1  0
  1 40  1  0
 34 82  1  0
 34 83  1  0
 34 84  1  0
 32 81  1  1
 31 79  1  0
 31 80  1  0
 30 77  1  0
 30 78  1  0
 29 74  1  0
 29 75  1  0
 29 76  1  0
 37 85  1  0
 15 51  1  1
 16 52  1  6
 17 53  1  0
 17 54  1  0
 17 55  1  0
M  END


  Mrv1533004161523412D          

 37 41  0  0  0  0            999 V2000
   -0.1105   -3.1086    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3020   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1105   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3020   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1270   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5395   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3645   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7770   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1895   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3645   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7770   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6020   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0145   -3.1086    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.0145   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.8395   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4270   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2520   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0770   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4895   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.3145   -4.5375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.7270   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.3145   -3.1086    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.5520   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0770   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9337   -6.0644    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2520   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.8395   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0145   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6020   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6882   -6.0725    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.8522   -5.5341    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.4842   -5.0038    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.9955   -6.3466    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.5395   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1270   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5395   -3.1086    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  1  0  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  5  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  1  0  0  0  0
  9 11  1  0  0  0  0
 11 12  2  0  0  0  0
 12 13  1  0  0  0  0
 13 14  2  0  0  0  0
 13 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 16 18  1  0  0  0  0
 18 19  1  0  0  0  0
 19 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  2  0  0  0  0
 22 24  1  0  0  0  0
 20 25  1  0  0  0  0
 25 26  1  0  0  0  0
 25 27  1  0  0  0  0
 16 27  1  0  0  0  0
 27 28  1  0  0  0  0
 28 29  1  0  0  0  0
 29 30  1  0  0  0  0
  9 30  1  0  0  0  0
 15 30  1  0  0  0  0
 30 31  1  0  0  0  0
 25 32  1  0  0  0  0
 32 33  2  0  0  0  0
 32 34  1  0  0  0  0
 11 35  1  0  0  0  0
  5 35  1  0  0  0  0
 35 36  1  0  0  0  0
  2 36  1  0  0  0  0
 36 37  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0290233

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CC1CCC2(C)CCC3(C)C(=CC(=O)C4C5(C)CCC(OC(C)=O)C(C)(C5CCC34C)C(O)=O)C2C1C

> <INCHI_IDENTIFIER>
InChI=1S/C32H48O5/c1-18-9-12-28(4)15-16-30(6)21(25(28)19(18)2)17-22(34)26-29(5)13-11-24(37-20(3)33)32(8,27(35)36)23(29)10-14-31(26,30)7/h17-19,23-26H,9-16H2,1-8H3,(H,35,36)

> <INCHI_KEY>
HMMGKOVEOFBCAU-UHFFFAOYSA-N

> <FORMULA>
C32H48O5

> <MOLECULAR_WEIGHT>
512.731

> <EXACT_MASS>
512.350174646

> <JCHEM_ACCEPTOR_COUNT>
4

> <JCHEM_ATOM_COUNT>
85

> <JCHEM_AVERAGE_POLARIZABILITY>
59.780200262415214

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
1

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
3-(acetyloxy)-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicene-4-carboxylic acid

> <ALOGPS_LOGP>
5.90

> <JCHEM_LOGP>
6.459425422999997

> <ALOGPS_LOGS>
-6.06

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
5

> <JCHEM_PHYSIOLOGICAL_CHARGE>
-1

> <JCHEM_PKA_STRONGEST_ACIDIC>
4.319016198507818

> <JCHEM_PKA_STRONGEST_BASIC>
-5.112343197938021

> <JCHEM_POLAR_SURFACE_AREA>
80.67

> <JCHEM_REFRACTIVITY>
143.49350000000004

> <JCHEM_ROTATABLE_BOND_COUNT>
3

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
4.50e-04 g/l

> <JCHEM_TRADITIONAL_IUPAC>
3-(acetyloxy)-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4a,5,6,7,8,9,10,11,12,12a,14a-tetradecahydropicene-4-carboxylic acid

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 16-APR-15   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   16-APR-15         0                                  
HETATM    1  C   UNK     0      -0.206  -5.803   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       0.564  -7.136   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      -0.206  -8.470   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       0.564  -9.804   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       2.104  -9.804   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       1.334 -11.137   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       2.874 -11.137   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       4.414 -11.137   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       5.184  -9.804   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       5.954 -11.137   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       4.414  -8.470   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       5.184  -7.136   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       6.724  -7.136   0.000  0.00  0.00           C+0
HETATM   14  O   UNK     0       7.494  -5.803   0.000  0.00  0.00           O+0
HETATM   15  C   UNK     0       7.494  -8.470   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       9.034  -8.470   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       8.264  -7.136   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       9.804  -7.136   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0      11.344  -7.136   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0      12.114  -8.470   0.000  0.00  0.00           C+0
HETATM   21  O   UNK     0      13.654  -8.470   0.000  0.00  0.00           O+0
HETATM   22  C   UNK     0      14.424  -7.136   0.000  0.00  0.00           C+0
HETATM   23  O   UNK     0      13.654  -5.803   0.000  0.00  0.00           O+0
HETATM   24  C   UNK     0      15.964  -7.136   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0      11.344  -9.804   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0      11.076 -11.320   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0       9.804  -9.804   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0       9.034 -11.137   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0       7.494 -11.137   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0       6.724  -9.804   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0       6.885 -11.335   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0      12.791 -10.330   0.000  0.00  0.00           C+0
HETATM   33  O   UNK     0      13.971  -9.340   0.000  0.00  0.00           O+0
HETATM   34  O   UNK     0      13.058 -11.847   0.000  0.00  0.00           O+0
HETATM   35  C   UNK     0       2.874  -8.470   0.000  0.00  0.00           C+0
HETATM   36  C   UNK     0       2.104  -7.136   0.000  0.00  0.00           C+0
HETATM   37  C   UNK     0       2.874  -5.803   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3   36                                                  
CONECT    3    2    4                                                       
CONECT    4    3    5                                                       
CONECT    5    4    6    7   35                                             
CONECT    6    5                                                            
CONECT    7    5    8                                                       
CONECT    8    7    9                                                       
CONECT    9    8   10   11   30                                             
CONECT   10    9                                                            
CONECT   11    9   12   35                                                  
CONECT   12   11   13                                                       
CONECT   13   12   14   15                                                  
CONECT   14   13                                                            
CONECT   15   13   16   30                                                  
CONECT   16   15   17   18   27                                             
CONECT   17   16                                                            
CONECT   18   16   19                                                       
CONECT   19   18   20                                                       
CONECT   20   19   21   25                                                  
CONECT   21   20   22                                                       
CONECT   22   21   23   24                                                  
CONECT   23   22                                                            
CONECT   24   22                                                            
CONECT   25   20   26   27   32                                             
CONECT   26   25                                                            
CONECT   27   25   16   28                                                  
CONECT   28   27   29                                                       
CONECT   29   28   30                                                       
CONECT   30   29    9   15   31                                             
CONECT   31   30                                                            
CONECT   32   25   33   34                                                  
CONECT   33   32                                                            
CONECT   34   32                                                            
CONECT   35   11    5   36                                                  
CONECT   36   35    2   37                                                  
CONECT   37   36                                                            
MASTER        0    0    0    0    0    0    0    0   37    0   82    0
END

View in JSmol

Synonyms

Value	Source
3-O-Acetyl-11-keto-boswellic acid	MeSH
Acetyl-11-keto-beta-boswellic acid	MeSH
Acetyl-11-ketoboswellic acid	MeSH
Acetyl-11-keto-boswellic acid	MeSH
AKBA CPD	MeSH
AcKBA	MeSH
3-(Acetyloxy)-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicene-4-carboxylate	Generator

Chemical Formula

C₃₂H₄₈O₅

Average Mass

512.7310 Da

Monoisotopic Mass

512.35017 Da

IUPAC Name

3-(acetyloxy)-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicene-4-carboxylic acid

Traditional Name

3-(acetyloxy)-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4a,5,6,7,8,9,10,11,12,12a,14a-tetradecahydropicene-4-carboxylic acid

CAS Registry Number

Not Available

SMILES

CC1CCC2(C)CCC3(C)C(=CC(=O)C4C5(C)CCC(OC(C)=O)C(C)(C5CCC34C)C(O)=O)C2C1C

InChI Identifier

InChI=1S/C32H48O5/c1-18-9-12-28(4)15-16-30(6)21(25(28)19(18)2)17-22(34)26-29(5)13-11-24(37-20(3)33)32(8,27(35)36)23(29)10-14-31(26,30)7/h17-19,23-26H,9-16H2,1-8H3,(H,35,36)

InChI Key

HMMGKOVEOFBCAU-UHFFFAOYSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Boswellia papyrifera	LOTUS Database	35616633
Boswellia sacra	LOTUS Database	35616633
Boswellia serrata	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as triterpenoids. These are terpene molecules containing six isoprene units.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Prenol lipids

Sub Class

Triterpenoids

Direct Parent

Triterpenoids

Alternative Parents

Substituents

Triterpenoid
15-hydroxysteroid
Hydroxysteroid
Steroid
Cyclohexenone
Dicarboxylic acid or derivatives
Carboxylic acid ester
Ketone
Carboxylic acid derivative
Carboxylic acid
Organic oxide
Carbonyl group
Organic oxygen compound
Hydrocarbon derivative
Organooxygen compound
Aliphatic homopolycyclic compound

Molecular Framework

Aliphatic homopolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	5.9	ALOGPS
logP	6.46	ChemAxon
logS	-6.1	ALOGPS
pKa (Strongest Acidic)	4.32	ChemAxon
pKa (Strongest Basic)	-5.1	ChemAxon
Physiological Charge	-1	ChemAxon
Hydrogen Acceptor Count	4	ChemAxon
Hydrogen Donor Count	1	ChemAxon
Polar Surface Area	80.67 Å²	ChemAxon
Rotatable Bond Count	3	ChemAxon
Refractivity	143.49 m³·mol⁻¹	ChemAxon
Polarizability	59.78 Å³	ChemAxon
Number of Rings	5	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Boswellic acid

METLIN ID

Not Available

PubChem Compound

17973666

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for 3-(acetyloxy)-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4a,5,6,7,8,9,10,11,12,12a,14a-tetradecahydropicene-4-carboxylic acid (NP0290233)

MOL for NP0290233 (3-(acetyloxy)-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4a,5,6,7,8,9,10,11,12,12a,14a-tetradecahydropicene-4-carboxylic acid)

3D MOL for NP0290233 (3-(acetyloxy)-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4a,5,6,7,8,9,10,11,12,12a,14a-tetradecahydropicene-4-carboxylic acid)

3D SDF for NP0290233 (3-(acetyloxy)-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4a,5,6,7,8,9,10,11,12,12a,14a-tetradecahydropicene-4-carboxylic acid)

3D-SDF for NP0290233 (3-(acetyloxy)-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4a,5,6,7,8,9,10,11,12,12a,14a-tetradecahydropicene-4-carboxylic acid)

PDB for NP0290233 (3-(acetyloxy)-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4a,5,6,7,8,9,10,11,12,12a,14a-tetradecahydropicene-4-carboxylic acid)

3D PDB for NP0290233 (3-(acetyloxy)-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4a,5,6,7,8,9,10,11,12,12a,14a-tetradecahydropicene-4-carboxylic acid)

SMILES for NP0290233 (3-(acetyloxy)-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4a,5,6,7,8,9,10,11,12,12a,14a-tetradecahydropicene-4-carboxylic acid)

INCHI for NP0290233 (3-(acetyloxy)-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4a,5,6,7,8,9,10,11,12,12a,14a-tetradecahydropicene-4-carboxylic acid)

Structure for NP0290233 (3-(acetyloxy)-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4a,5,6,7,8,9,10,11,12,12a,14a-tetradecahydropicene-4-carboxylic acid)

3D Structure for NP0290233 (3-(acetyloxy)-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4a,5,6,7,8,9,10,11,12,12a,14a-tetradecahydropicene-4-carboxylic acid)