NP-MRD: Showing NP-Card for (1'r,2r,2's,4'r,5's,6'r,7's,8's)-5'-[(2s,3ar,6as)-hexahydrofuro[2,3-b]furan-2-yl]-2'-(acetyloxy)-7'-hydroxy-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecan]-11'-yl (2e)-2-methylbut-2-enoate (NP0288230)

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Record Information

Version

2.0

Created at

2022-09-09 17:51:00 UTC

Updated at

2022-09-09 17:51:00 UTC

NP-MRD ID

NP0288230

Secondary Accession Numbers

None

Natural Product Identification

Common Name

(1'r,2r,2's,4'r,5's,6'r,7's,8's)-5'-[(2s,3ar,6as)-hexahydrofuro[2,3-b]furan-2-yl]-2'-(acetyloxy)-7'-hydroxy-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecan]-11'-yl (2e)-2-methylbut-2-enoate

Description

Ajugapyrin A belongs to the class of organic compounds known as furofurans. These are organic compounds containing a two furan rings fused to each other. Furan is a five-membered aromatic ring with four carbon atoms and one oxygen atom. (1'r,2r,2's,4'r,5's,6'r,7's,8's)-5'-[(2s,3ar,6as)-hexahydrofuro[2,3-b]furan-2-yl]-2'-(acetyloxy)-7'-hydroxy-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecan]-11'-yl (2e)-2-methylbut-2-enoate is found in Ajuga pyramidalis. Based on a literature review very few articles have been published on Ajugapyrin A.

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652309092219512D          

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M  END

     RDKit          3D

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M  END


  Mrv1652309092219512D          

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    2.4403   -1.6565    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.1331   -2.5009    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  2  0  0  0  0
  3  4  1  0  0  0  0
  3  5  1  0  0  0  0
  5  6  2  0  0  0  0
  5  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
 10  9  1  6  0  0  0
 10 11  1  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 12 14  1  6  0  0  0
 15 12  1  1  0  0  0
  8 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  6  0  0  0
 17 18  1  0  0  0  0
 18 19  1  0  0  0  0
 18 20  2  0  0  0  0
 16 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  1  6  0  0  0
 22 24  1  0  0  0  0
 24 25  1  6  0  0  0
 24 26  1  1  0  0  0
 26 27  1  0  0  0  0
 28 27  1  6  0  0  0
 28 29  1  0  0  0  0
 29 30  1  0  0  0  0
 30 31  1  0  0  0  0
 32 31  1  6  0  0  0
 28 32  1  0  0  0  0
 32 33  1  0  0  0  0
 26 33  1  1  0  0  0
 34 24  1  6  0  0  0
 15 34  1  0  0  0  0
 34 35  1  0  0  0  0
 10 35  1  0  0  0  0
 35 36  1  1  0  0  0
M  END
> <DATABASE_ID>
NP0288230

> <DATABASE_NAME>
NP-MRD

> <SMILES>
C\C=C(/C)C(=O)OC1O[C@H]2C[C@]3(CO3)[C@@]11[C@H](C[C@@H](C)[C@](C)([C@@H]3C[C@H]4CCO[C@H]4O3)[C@H]1[C@@H]2O)OC(C)=O

> <INCHI_IDENTIFIER>
InChI=1S/C27H38O9/c1-6-13(2)22(30)36-24-27-19(33-15(4)28)9-14(3)25(5,18-10-16-7-8-31-23(16)35-18)21(27)20(29)17(34-24)11-26(27)12-32-26/h6,14,16-21,23-24,29H,7-12H2,1-5H3/b13-6+/t14-,16-,17+,18+,19+,20-,21-,23+,24?,25-,26+,27-/m1/s1

> <INCHI_KEY>
LCUUDDVODSPJLB-WAQASEDFSA-N

> <FORMULA>
C27H38O9

> <MOLECULAR_WEIGHT>
506.592

> <EXACT_MASS>
506.251582804

> <JCHEM_ACCEPTOR_COUNT>
7

> <JCHEM_ATOM_COUNT>
74

> <JCHEM_AVERAGE_POLARIZABILITY>
52.74764771911215

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
1

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(1'R,2R,2'S,4'R,5'S,6'R,7'S,8'S)-5'-[(2S,3aR,6aS)-hexahydrofuro[2,3-b]furan-2-yl]-2'-(acetyloxy)-7'-hydroxy-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0^{1,6}]dodecane]-11'-yl (2E)-2-methylbut-2-enoate

> <JCHEM_LOGP>
2.3729625476666643

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
6

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA_STRONGEST_ACIDIC>
13.886041558095236

> <JCHEM_PKA_STRONGEST_BASIC>
-3.2860454224891438

> <JCHEM_POLAR_SURFACE_AREA>
113.05000000000003

> <JCHEM_REFRACTIVITY>
125.35279999999999

> <JCHEM_ROTATABLE_BOND_COUNT>
6

> <JCHEM_RULE_OF_FIVE>
0

> <JCHEM_TRADITIONAL_IUPAC>
(1'R,2R,2'S,4'R,5'S,6'R,7'S,8'S)-5'-[(2S,3aR,6aS)-hexahydrofuro[2,3-b]furan-2-yl]-2'-(acetyloxy)-7'-hydroxy-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0^{1,6}]dodecane]-11'-yl (2E)-2-methylbut-2-enoate

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 09-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   09-SEP-22         0                                  
HETATM    1  C   UNK     0      13.756  -3.866   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      12.243  -4.156   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      11.236  -2.991   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      11.741  -1.536   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       9.723  -3.282   0.000  0.00  0.00           C+0
HETATM    6  O   UNK     0       9.219  -4.737   0.000  0.00  0.00           O+0
HETATM    7  O   UNK     0       8.684  -2.080   0.000  0.00  0.00           O+0
HETATM    8  C   UNK     0       6.963  -1.670   0.000  0.00  0.00           C+0
HETATM    9  O   UNK     0       7.516  -3.127   0.000  0.00  0.00           O+0
HETATM   10  C   UNK     0       6.042  -3.642   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       5.963  -2.058   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       6.828  -0.561   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       7.449   0.849   0.000  0.00  0.00           C+0
HETATM   14  O   UNK     0       8.359  -0.393   0.000  0.00  0.00           O+0
HETATM   15  C   UNK     0       5.412  -0.734   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       4.768   0.799   0.000  0.00  0.00           C+0
HETATM   17  O   UNK     0       4.891   2.435   0.000  0.00  0.00           O+0
HETATM   18  C   UNK     0       5.071   4.005   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       3.834   4.922   0.000  0.00  0.00           C+0
HETATM   20  O   UNK     0       6.484   4.618   0.000  0.00  0.00           O+0
HETATM   21  C   UNK     0       3.427   1.645   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0       2.263   0.596   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0       0.923   1.308   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0       2.479  -0.958   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0       1.904  -2.440   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0       0.940  -0.906   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0       0.077   0.370   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0      -1.403  -0.056   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0      -2.850   0.469   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0      -3.797  -0.746   0.000  0.00  0.00           C+0
HETATM   31  O   UNK     0      -2.934  -2.021   0.000  0.00  0.00           O+0
HETATM   32  C   UNK     0      -1.455  -1.595   0.000  0.00  0.00           C+0
HETATM   33  O   UNK     0      -0.007  -2.120   0.000  0.00  0.00           O+0
HETATM   34  C   UNK     0       3.989  -1.557   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0       4.555  -3.092   0.000  0.00  0.00           C+0
HETATM   36  O   UNK     0       3.982  -4.668   0.000  0.00  0.00           O+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4    5                                                  
CONECT    4    3                                                            
CONECT    5    3    6    7                                                  
CONECT    6    5                                                            
CONECT    7    5    8                                                       
CONECT    8    7    9   15                                                  
CONECT    9    8   10                                                       
CONECT   10    9   11   35                                                  
CONECT   11   10   12                                                       
CONECT   12   11   13   14   15                                             
CONECT   13   12   14                                                       
CONECT   14   13   12                                                       
CONECT   15   12    8   16   34                                             
CONECT   16   15   17   21                                                  
CONECT   17   16   18                                                       
CONECT   18   17   19   20                                                  
CONECT   19   18                                                            
CONECT   20   18                                                            
CONECT   21   16   22                                                       
CONECT   22   21   23   24                                                  
CONECT   23   22                                                            
CONECT   24   22   25   26   34                                             
CONECT   25   24                                                            
CONECT   26   24   27   33                                                  
CONECT   27   26   28                                                       
CONECT   28   27   29   32                                                  
CONECT   29   28   30                                                       
CONECT   30   29   31                                                       
CONECT   31   30   32                                                       
CONECT   32   31   28   33                                                  
CONECT   33   32   26                                                       
CONECT   34   24   15   35                                                  
CONECT   35   34   10   36                                                  
CONECT   36   35                                                            
MASTER        0    0    0    0    0    0    0    0   36    0   82    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₂₇H₃₈O₉

Average Mass

506.5920 Da

Monoisotopic Mass

506.25158 Da

IUPAC Name

(1'R,2R,2'S,4'R,5'S,6'R,7'S,8'S)-5'-[(2S,3aR,6aS)-hexahydrofuro[2,3-b]furan-2-yl]-2'-(acetyloxy)-7'-hydroxy-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0^{1,6}]dodecane]-11'-yl (2E)-2-methylbut-2-enoate

Traditional Name

CAS Registry Number

Not Available

SMILES

C\C=C(/C)C(=O)OC1O[C@H]2C[C@]3(CO3)[C@@]11[C@H](C[C@@H](C)[C@](C)([C@@H]3C[C@H]4CCO[C@H]4O3)[C@H]1[C@@H]2O)OC(C)=O

InChI Identifier

InChI=1S/C27H38O9/c1-6-13(2)22(30)36-24-27-19(33-15(4)28)9-14(3)25(5,18-10-16-7-8-31-23(16)35-18)21(27)20(29)17(34-24)11-26(27)12-32-26/h6,14,16-21,23-24,29H,7-12H2,1-5H3/b13-6+/t14-,16-,17+,18+,19+,20-,21-,23+,24?,25-,26+,27-/m1/s1

InChI Key

LCUUDDVODSPJLB-WAQASEDFSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Ajuga pyramidalis	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as furofurans. These are organic compounds containing a two furan rings fused to each other. Furan is a five-membered aromatic ring with four carbon atoms and one oxygen atom.

Kingdom

Organic compounds

Super Class

Organoheterocyclic compounds

Class

Furofurans

Sub Class

Not Available

Direct Parent

Furofurans

Alternative Parents

Substituents

Furofuran
Fatty acid ester
Fatty acyl
Oxane
Dicarboxylic acid or derivatives
Alpha,beta-unsaturated carboxylic ester
Enoate ester
Tetrahydrofuran
Cyclic alcohol
Secondary alcohol
Carboxylic acid ester
Oxacycle
Ether
Oxirane
Dialkyl ether
Carboxylic acid derivative
Acetal
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Carbonyl group
Alcohol
Aliphatic heteropolycyclic compound

Molecular Framework

Aliphatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	2.37	ChemAxon
pKa (Strongest Acidic)	13.89	ChemAxon
pKa (Strongest Basic)	-3.3	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	7	ChemAxon
Hydrogen Donor Count	1	ChemAxon
Polar Surface Area	113.05 Å²	ChemAxon
Rotatable Bond Count	6	ChemAxon
Refractivity	125.35 m³·mol⁻¹	ChemAxon
Polarizability	52.75 Å³	ChemAxon
Number of Rings	6	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	Yes	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

C00049102

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

101939211

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for (1'r,2r,2's,4'r,5's,6'r,7's,8's)-5'-[(2s,3ar,6as)-hexahydrofuro[2,3-b]furan-2-yl]-2'-(acetyloxy)-7'-hydroxy-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecan]-11'-yl (2e)-2-methylbut-2-enoate (NP0288230)

MOL for NP0288230 ((1'r,2r,2's,4'r,5's,6'r,7's,8's)-5'-[(2s,3ar,6as)-hexahydrofuro[2,3-b]furan-2-yl]-2'-(acetyloxy)-7'-hydroxy-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecan]-11'-yl (2e)-2-methylbut-2-enoate)

3D MOL for NP0288230 ((1'r,2r,2's,4'r,5's,6'r,7's,8's)-5'-[(2s,3ar,6as)-hexahydrofuro[2,3-b]furan-2-yl]-2'-(acetyloxy)-7'-hydroxy-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecan]-11'-yl (2e)-2-methylbut-2-enoate)

3D SDF for NP0288230 ((1'r,2r,2's,4'r,5's,6'r,7's,8's)-5'-[(2s,3ar,6as)-hexahydrofuro[2,3-b]furan-2-yl]-2'-(acetyloxy)-7'-hydroxy-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecan]-11'-yl (2e)-2-methylbut-2-enoate)

3D-SDF for NP0288230 ((1'r,2r,2's,4'r,5's,6'r,7's,8's)-5'-[(2s,3ar,6as)-hexahydrofuro[2,3-b]furan-2-yl]-2'-(acetyloxy)-7'-hydroxy-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecan]-11'-yl (2e)-2-methylbut-2-enoate)

PDB for NP0288230 ((1'r,2r,2's,4'r,5's,6'r,7's,8's)-5'-[(2s,3ar,6as)-hexahydrofuro[2,3-b]furan-2-yl]-2'-(acetyloxy)-7'-hydroxy-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecan]-11'-yl (2e)-2-methylbut-2-enoate)

3D PDB for NP0288230 ((1'r,2r,2's,4'r,5's,6'r,7's,8's)-5'-[(2s,3ar,6as)-hexahydrofuro[2,3-b]furan-2-yl]-2'-(acetyloxy)-7'-hydroxy-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecan]-11'-yl (2e)-2-methylbut-2-enoate)

SMILES for NP0288230 ((1'r,2r,2's,4'r,5's,6'r,7's,8's)-5'-[(2s,3ar,6as)-hexahydrofuro[2,3-b]furan-2-yl]-2'-(acetyloxy)-7'-hydroxy-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecan]-11'-yl (2e)-2-methylbut-2-enoate)

INCHI for NP0288230 ((1'r,2r,2's,4'r,5's,6'r,7's,8's)-5'-[(2s,3ar,6as)-hexahydrofuro[2,3-b]furan-2-yl]-2'-(acetyloxy)-7'-hydroxy-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecan]-11'-yl (2e)-2-methylbut-2-enoate)

Structure for NP0288230 ((1'r,2r,2's,4'r,5's,6'r,7's,8's)-5'-[(2s,3ar,6as)-hexahydrofuro[2,3-b]furan-2-yl]-2'-(acetyloxy)-7'-hydroxy-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecan]-11'-yl (2e)-2-methylbut-2-enoate)

3D Structure for NP0288230 ((1'r,2r,2's,4'r,5's,6'r,7's,8's)-5'-[(2s,3ar,6as)-hexahydrofuro[2,3-b]furan-2-yl]-2'-(acetyloxy)-7'-hydroxy-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecan]-11'-yl (2e)-2-methylbut-2-enoate)