NP-MRD: Showing NP-Card for 11'-hydroxy-5'-{5-hydroxy-hexahydrofuro[2,3-b]furan-2-yl}-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecan]-2'-yl acetate (NP0287912)

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Record Information

Version

2.0

Created at

2022-09-09 17:23:53 UTC

Updated at

2022-09-09 17:23:53 UTC

NP-MRD ID

NP0287912

Secondary Accession Numbers

None

Natural Product Identification

Common Name

11'-hydroxy-5'-{5-hydroxy-hexahydrofuro[2,3-b]furan-2-yl}-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecan]-2'-yl acetate

Description

11'-Hydroxy-5'-{5-hydroxy-hexahydrofuro[2,3-b]furan-2-yl}-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]Dodecane]-2'-yl acetate belongs to the class of organic compounds known as furofurans. These are organic compounds containing a two furan rings fused to each other. Furan is a five-membered aromatic ring with four carbon atoms and one oxygen atom. 11'-hydroxy-5'-{5-hydroxy-hexahydrofuro[2,3-b]furan-2-yl}-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecan]-2'-yl acetate is found in Scutellaria albida and Scutellaria discolor. 11'-Hydroxy-5'-{5-hydroxy-hexahydrofuro[2,3-b]furan-2-yl}-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]Dodecane]-2'-yl acetate is an extremely weak basic (essentially neutral) compound (based on its pKa).

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1533004171511102D          

 30 35  0  0  0  0            999 V2000
   -1.1279    0.9562    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3528    0.6735    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.2710    1.2350    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9895    0.7818    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6189    1.3151    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.4718    2.1269    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6953    2.4054    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1013    2.6602    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3345   -0.0395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1650   -0.5405    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.9307   -0.2335    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.4616   -1.3214    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.6718   -1.5973    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8752   -1.3025    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5719   -0.4803    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2370   -0.1591    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5701   -0.9139    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0492   -0.3036    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4098   -1.0456    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2269   -0.9320    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9548   -1.3204    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5491   -0.7482    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3613   -0.8927    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1885   -0.0062    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3714   -0.1198    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6435    0.2686    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.6294   -0.7487    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0929    0.0537    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4253    0.8087    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.9130    0.1433    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  1  0  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  6  7  2  0  0  0  0
  6  8  1  0  0  0  0
  4  9  1  0  0  0  0
  9 10  1  0  0  0  0
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  9 28  1  0  0  0  0
 28 29  1  0  0  0  0
 29 30  1  0  0  0  0
 28 30  1  0  0  0  0
M  END

     RDKit          3D

 62 67  0  0  0  0  0  0  0  0999 V2000
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M  END


  Mrv1533004171511102D          

 30 35  0  0  0  0            999 V2000
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   -0.3528    0.6735    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
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    1.6189    1.3151    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
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M  END
> <DATABASE_ID>
NP0287912

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CC1CC(OC(C)=O)C23C(O)OC(CC2C1(C)C1CC2CC(O)OC2O1)CC31CO1

> <INCHI_IDENTIFIER>
InChI=1S/C22H32O8/c1-10-4-16(27-11(2)23)22-14(7-13(28-19(22)25)8-21(22)9-26-21)20(10,3)15-5-12-6-17(24)30-18(12)29-15/h10,12-19,24-25H,4-9H2,1-3H3

> <INCHI_KEY>
VNNHJRDFAKPJHC-UHFFFAOYSA-N

> <FORMULA>
C22H32O8

> <MOLECULAR_WEIGHT>
424.49

> <EXACT_MASS>
424.20971799

> <JCHEM_ACCEPTOR_COUNT>
7

> <JCHEM_ATOM_COUNT>
62

> <JCHEM_AVERAGE_POLARIZABILITY>
43.71711840298373

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
2

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
11'-hydroxy-5'-{5-hydroxy-hexahydrofuro[2,3-b]furan-2-yl}-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecane]-2'-yl acetate

> <ALOGPS_LOGP>
0.66

> <JCHEM_LOGP>
0.5640497823333327

> <ALOGPS_LOGS>
-2.51

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
6

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
12.485442614392294

> <JCHEM_PKA_STRONGEST_ACIDIC>
11.679790713371876

> <JCHEM_PKA_STRONGEST_BASIC>
-3.737441028973866

> <JCHEM_POLAR_SURFACE_AREA>
106.98000000000002

> <JCHEM_REFRACTIVITY>
101.37879999999998

> <JCHEM_ROTATABLE_BOND_COUNT>
3

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
1.32e+00 g/l

> <JCHEM_TRADITIONAL_IUPAC>
11'-hydroxy-5'-{5-hydroxy-hexahydrofuro[2,3-b]furan-2-yl}-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecane]-2'-yl acetate

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 17-APR-15   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   17-APR-15         0                                  
HETATM    1  C   UNK     0      -2.105   1.785   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      -0.659   1.257   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       0.506   2.305   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       1.847   1.459   0.000  0.00  0.00           C+0
HETATM    5  O   UNK     0       3.022   2.455   0.000  0.00  0.00           O+0
HETATM    6  C   UNK     0       2.747   3.970   0.000  0.00  0.00           C+0
HETATM    7  O   UNK     0       1.298   4.490   0.000  0.00  0.00           O+0
HETATM    8  C   UNK     0       3.922   4.966   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       2.491  -0.074   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       4.041  -1.009   0.000  0.00  0.00           C+0
HETATM   11  O   UNK     0       5.471  -0.436   0.000  0.00  0.00           O+0
HETATM   12  O   UNK     0       4.595  -2.467   0.000  0.00  0.00           O+0
HETATM   13  C   UNK     0       3.121  -2.982   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       1.634  -2.431   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       1.068  -0.896   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0      -0.442  -0.297   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0      -1.064  -1.706   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0      -1.959  -0.567   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0      -2.632  -1.952   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0      -4.157  -1.740   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0      -5.516  -2.465   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0      -6.625  -1.397   0.000  0.00  0.00           C+0
HETATM   23  O   UNK     0      -8.141  -1.666   0.000  0.00  0.00           O+0
HETATM   24  O   UNK     0      -5.952  -0.011   0.000  0.00  0.00           O+0
HETATM   25  C   UNK     0      -4.427  -0.224   0.000  0.00  0.00           C+0
HETATM   26  O   UNK     0      -3.068   0.501   0.000  0.00  0.00           O+0
HETATM   27  C   UNK     0       3.041  -1.398   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0       3.907   0.100   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0       4.527   1.510   0.000  0.00  0.00           C+0
HETATM   30  O   UNK     0       5.438   0.268   0.000  0.00  0.00           O+0
CONECT    1    2                                                            
CONECT    2    1    3   16                                                  
CONECT    3    2    4                                                       
CONECT    4    3    5    9                                                  
CONECT    5    4    6                                                       
CONECT    6    5    7    8                                                  
CONECT    7    6                                                            
CONECT    8    6                                                            
CONECT    9    4   10   15   28                                             
CONECT   10    9   11   12                                                  
CONECT   11   10                                                            
CONECT   12   10   13                                                       
CONECT   13   12   14   27                                                  
CONECT   14   13   15                                                       
CONECT   15   14    9   16                                                  
CONECT   16   15    2   17   18                                             
CONECT   17   16                                                            
CONECT   18   16   19   26                                                  
CONECT   19   18   20                                                       
CONECT   20   19   21   25                                                  
CONECT   21   20   22                                                       
CONECT   22   21   23   24                                                  
CONECT   23   22                                                            
CONECT   24   22   25                                                       
CONECT   25   24   20   26                                                  
CONECT   26   25   18                                                       
CONECT   27   13   28                                                       
CONECT   28   27    9   29   30                                             
CONECT   29   28   30                                                       
CONECT   30   29   28                                                       
MASTER        0    0    0    0    0    0    0    0   30    0   70    0
END

View in JSmol

Synonyms

Value	Source
11'-Hydroxy-5'-{5-hydroxy-hexahydrofuro[2,3-b]furan-2-yl}-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0,]dodecane]-2'-yl acetic acid	Generator
11'-Hydroxy-5'-{5-hydroxy-hexahydrofuro[2,3-b]furan-2-yl}-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecane]-2'-yl acetic acid	Generator

Chemical Formula

C₂₂H₃₂O₈

Average Mass

424.4900 Da

Monoisotopic Mass

424.20972 Da

IUPAC Name

11'-hydroxy-5'-{5-hydroxy-hexahydrofuro[2,3-b]furan-2-yl}-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecane]-2'-yl acetate

Traditional Name

11'-hydroxy-5'-{5-hydroxy-hexahydrofuro[2,3-b]furan-2-yl}-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecane]-2'-yl acetate

CAS Registry Number

Not Available

SMILES

CC1CC(OC(C)=O)C23C(O)OC(CC2C1(C)C1CC2CC(O)OC2O1)CC31CO1

InChI Identifier

InChI=1S/C22H32O8/c1-10-4-16(27-11(2)23)22-14(7-13(28-19(22)25)8-21(22)9-26-21)20(10,3)15-5-12-6-17(24)30-18(12)29-15/h10,12-19,24-25H,4-9H2,1-3H3

InChI Key

VNNHJRDFAKPJHC-UHFFFAOYSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Scutellaria albida	LOTUS Database	35616633
Scutellaria discolor	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as furofurans. These are organic compounds containing a two furan rings fused to each other. Furan is a five-membered aromatic ring with four carbon atoms and one oxygen atom.

Kingdom

Organic compounds

Super Class

Organoheterocyclic compounds

Class

Furofurans

Sub Class

Not Available

Direct Parent

Furofurans

Alternative Parents

Substituents

Furofuran
Oxane
Tetrahydrofuran
Carboxylic acid ester
Hemiacetal
Monocarboxylic acid or derivatives
Ether
Oxirane
Dialkyl ether
Acetal
Carboxylic acid derivative
Oxacycle
Organic oxide
Organooxygen compound
Organic oxygen compound
Carbonyl group
Hydrocarbon derivative
Aliphatic heteropolycyclic compound

Molecular Framework

Aliphatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	0.66	ALOGPS
logP	0.56	ChemAxon
logS	-2.5	ALOGPS
pKa (Strongest Acidic)	11.68	ChemAxon
pKa (Strongest Basic)	-3.7	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	7	ChemAxon
Hydrogen Donor Count	2	ChemAxon
Polar Surface Area	106.98 Å²	ChemAxon
Rotatable Bond Count	3	ChemAxon
Refractivity	101.38 m³·mol⁻¹	ChemAxon
Polarizability	43.72 Å³	ChemAxon
Number of Rings	6	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

Not Available

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for 11'-hydroxy-5'-{5-hydroxy-hexahydrofuro[2,3-b]furan-2-yl}-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecan]-2'-yl acetate (NP0287912)

MOL for NP0287912 (11'-hydroxy-5'-{5-hydroxy-hexahydrofuro[2,3-b]furan-2-yl}-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecan]-2'-yl acetate)

3D MOL for NP0287912 (11'-hydroxy-5'-{5-hydroxy-hexahydrofuro[2,3-b]furan-2-yl}-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecan]-2'-yl acetate)

3D SDF for NP0287912 (11'-hydroxy-5'-{5-hydroxy-hexahydrofuro[2,3-b]furan-2-yl}-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecan]-2'-yl acetate)

3D-SDF for NP0287912 (11'-hydroxy-5'-{5-hydroxy-hexahydrofuro[2,3-b]furan-2-yl}-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecan]-2'-yl acetate)

PDB for NP0287912 (11'-hydroxy-5'-{5-hydroxy-hexahydrofuro[2,3-b]furan-2-yl}-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecan]-2'-yl acetate)

3D PDB for NP0287912 (11'-hydroxy-5'-{5-hydroxy-hexahydrofuro[2,3-b]furan-2-yl}-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecan]-2'-yl acetate)

SMILES for NP0287912 (11'-hydroxy-5'-{5-hydroxy-hexahydrofuro[2,3-b]furan-2-yl}-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecan]-2'-yl acetate)

INCHI for NP0287912 (11'-hydroxy-5'-{5-hydroxy-hexahydrofuro[2,3-b]furan-2-yl}-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecan]-2'-yl acetate)

Structure for NP0287912 (11'-hydroxy-5'-{5-hydroxy-hexahydrofuro[2,3-b]furan-2-yl}-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecan]-2'-yl acetate)

3D Structure for NP0287912 (11'-hydroxy-5'-{5-hydroxy-hexahydrofuro[2,3-b]furan-2-yl}-4',5'-dimethyl-12'-oxaspiro[oxirane-2,10'-tricyclo[6.2.2.0¹,⁶]dodecan]-2'-yl acetate)