NP-MRD: Showing NP-Card for (1s,4s,5r,6r,9s,10r,12r)-6-(acetyloxy)-7-[(acetyloxy)methyl]-5-hydroxy-3,11,11-trimethyl-15-oxotetracyclo[7.5.1.0¹,⁵.0¹⁰,¹²]pentadeca-2,7-dien-4-yl (2z)-2-methylbut-2-enoate (NP0284791)

Jump To Section:

Identification Spectra BioTaxonomy ChemoTaxonomy Physical properties Links References XML

Record Information

Version

2.0

Created at

2022-09-09 12:40:12 UTC

Updated at

2022-09-09 12:40:12 UTC

NP-MRD ID

NP0284791

Secondary Accession Numbers

None

Natural Product Identification

Common Name

(1s,4s,5r,6r,9s,10r,12r)-6-(acetyloxy)-7-[(acetyloxy)methyl]-5-hydroxy-3,11,11-trimethyl-15-oxotetracyclo[7.5.1.0¹,⁵.0¹⁰,¹²]pentadeca-2,7-dien-4-yl (2z)-2-methylbut-2-enoate

Description

CHEMBL562740 belongs to the class of organic compounds known as tricarboxylic acids and derivatives. These are carboxylic acids containing exactly three carboxyl groups. (1s,4s,5r,6r,9s,10r,12r)-6-(acetyloxy)-7-[(acetyloxy)methyl]-5-hydroxy-3,11,11-trimethyl-15-oxotetracyclo[7.5.1.0¹,⁵.0¹⁰,¹²]pentadeca-2,7-dien-4-yl (2z)-2-methylbut-2-enoate is found in Euphorbia royleana. Based on a literature review very few articles have been published on CHEMBL562740.

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652309092214402D          

 36 39  0  0  1  0            999 V2000
   -2.4014    1.3779    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1322    0.9951    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1661    0.1708    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8970   -0.2120    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4692   -0.2707    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5032   -1.0951    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7384    0.1120    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0415   -0.3295    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.0008   -1.1576    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6332   -1.6874    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1929   -1.3426    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3261   -0.6574    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.7898   -1.4107    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6097   -1.6445    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2721   -1.1201    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.2431   -0.2956    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.5837    0.2513    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.2746    1.0377    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4853    1.3255    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3879    2.1447    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0487    2.6386    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.8069    2.3133    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9042    1.4941    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4677    2.8072    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2167    0.8594    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.9315    1.2713    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9322    2.0963    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6471    2.5082    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2181    2.5094    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2695   -0.0102    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.9411    0.4689    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.9424   -0.2150    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4256   -0.8837    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.9716   -0.6827    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6304   -0.1861    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6636   -1.1319    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  2  0  0  0  0
  3  4  1  0  0  0  0
  3  5  1  0  0  0  0
  5  6  2  0  0  0  0
  5  7  1  0  0  0  0
  8  7  1  6  0  0  0
  8  9  1  0  0  0  0
  9 10  1  0  0  0  0
  9 11  2  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 15 14  1  6  0  0  0
 16 15  1  6  0  0  0
 16 17  1  0  0  0  0
 17 18  1  0  0  0  0
 18 19  2  0  0  0  0
 19 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  1  0  0  0  0
 22 24  2  0  0  0  0
 19 25  1  0  0  0  0
 25 26  1  6  0  0  0
 26 27  1  0  0  0  0
 27 28  1  0  0  0  0
 27 29  2  0  0  0  0
 25 30  1  0  0  0  0
  8 30  1  0  0  0  0
 12 30  1  0  0  0  0
 30 31  1  6  0  0  0
 17 32  1  1  0  0  0
 12 32  1  1  0  0  0
 32 33  2  0  0  0  0
 16 34  1  0  0  0  0
 15 34  1  0  0  0  0
 34 35  1  0  0  0  0
 34 36  1  0  0  0  0
M  END

     RDKit          3D

 72 75  0  0  0  0  0  0  0  0999 V2000
    3.4635   -2.9284   -0.1292 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7236   -2.1938    0.0553 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.8313   -0.9000   -0.1434 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.1310   -0.2371    0.0634 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6872   -0.1292   -0.5613 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.8061    1.1321   -0.7516 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.4187   -0.6409   -0.7865 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.3505    0.1983   -1.1974 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.8612   -0.1522   -2.5500 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6377    0.1774   -3.8004 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2883   -0.7565   -2.4381 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6601   -0.8625   -1.0667 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.5738   -2.3187   -0.5437 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8471   -3.0360   -0.7226 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1152   -2.7589   -0.1480 C   0  0  2  0  0  0  0  0  0  0  0  0
   -3.4912   -1.6420    0.7301 C   0  0  2  0  0  0  0  0  0  0  0  0
   -2.4405   -0.6628    0.7663 C   0  0  2  0  0  0  0  0  0  0  0  0
   -2.4997    0.6992    1.1996 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5189    1.5597    0.8890 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6123    2.8520    1.6125 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7376    3.8557    0.6576 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8525    5.2028    0.9096 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9762    6.1059   -0.2647 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8466    5.5878    2.0940 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3567    1.4658   -0.0429 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.6849    2.2054    0.5901 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.2515    3.3427    0.0983 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3511    4.0710    0.8225 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8712    3.8191   -0.9791 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.1692    0.0839   -0.2544 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.5387   -0.5064    0.9516 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0598   -0.5841   -0.7076 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9121   -0.3049   -1.4674 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4049   -3.0136    1.3280 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2612   -3.4223    2.1938 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.7226   -3.7011    1.7056 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6292   -4.0096    0.0941 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.7141   -2.4937    0.5886 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.1134   -2.8241   -1.1846 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.6139   -2.7629    0.3752 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.5248   -0.4346    1.0847 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.8961   -0.5901   -0.6736 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.0831    0.8578   -0.0436 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.7097    1.2603   -1.2937 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.2923   -0.4100   -4.6614 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.6814   -0.1328   -3.5851 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.5418    1.2443   -4.0628 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8891   -1.1326   -3.2839 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.1861   -2.7964   -1.1967 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1472   -2.3273    0.4750 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9377   -3.1099   -1.8612 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5955   -4.1257   -0.4888 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9858   -3.1410   -0.7803 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5256   -1.2410    0.6678 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6371   -1.1657    1.3872 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3247    1.0876    1.7868 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7357    3.0016    2.2929 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5010    2.8896    2.2713 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2084    7.1372   -0.0018 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9808    6.0447   -0.7951 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7024    5.6811   -1.0182 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6457    1.9270   -1.0100 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.8347    4.7945    1.4877 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.0309    4.5852    0.1428 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.8411    3.3270    1.4776 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.4979   -0.4422    1.1391 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8004   -2.6263    2.7854 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5196   -3.9737    1.5436 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5546   -4.2063    2.9548 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.4695   -3.3401    0.9709 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6348   -4.7843    1.5806 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9944   -3.3752    2.7225 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  2  0
  3  4  1  0
  3  5  1  0
  5  6  2  0
  5  7  1  0
  7  8  1  0
  8  9  1  0
  9 10  1  0
  9 11  2  0
 12 11  1  6
 12 13  1  0
 13 14  1  0
 14 15  1  0
 15 16  1  0
 16 17  1  0
 17 18  1  0
 18 19  2  0
 19 20  1  0
 20 21  1  0
 21 22  1  0
 22 23  1  0
 22 24  2  0
 19 25  1  0
 25 26  1  0
 26 27  1  0
 27 28  1  0
 27 29  2  0
 25 30  1  0
 30 31  1  1
 17 32  1  0
 32 33  2  0
 16 34  1  0
 34 35  1  0
 34 36  1  0
 30  8  1  0
 30 12  1  0
 32 12  1  0
 34 15  1  0
  1 37  1  0
  1 38  1  0
  1 39  1  0
  2 40  1  0
  4 41  1  0
  4 42  1  0
  4 43  1  0
  8 44  1  6
 10 45  1  0
 10 46  1  0
 10 47  1  0
 11 48  1  0
 13 49  1  0
 13 50  1  0
 14 51  1  0
 14 52  1  0
 15 53  1  6
 16 54  1  6
 17 55  1  1
 18 56  1  0
 20 57  1  0
 20 58  1  0
 23 59  1  0
 23 60  1  0
 23 61  1  0
 25 62  1  6
 28 63  1  0
 28 64  1  0
 28 65  1  0
 31 66  1  0
 35 67  1  0
 35 68  1  0
 35 69  1  0
 36 70  1  0
 36 71  1  0
 36 72  1  0
M  END


  Mrv1652309092214402D          

 36 39  0  0  1  0            999 V2000
   -2.4014    1.3779    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1322    0.9951    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1661    0.1708    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8970   -0.2120    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4692   -0.2707    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5032   -1.0951    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7384    0.1120    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0415   -0.3295    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.0008   -1.1576    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6332   -1.6874    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1929   -1.3426    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3261   -0.6574    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.7898   -1.4107    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6097   -1.6445    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2721   -1.1201    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.2431   -0.2956    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.5837    0.2513    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.2746    1.0377    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4853    1.3255    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3879    2.1447    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0487    2.6386    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.8069    2.3133    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9042    1.4941    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4677    2.8072    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2167    0.8594    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.9315    1.2713    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9322    2.0963    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6471    2.5082    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2181    2.5094    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2695   -0.0102    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.9411    0.4689    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.9424   -0.2150    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4256   -0.8837    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.9716   -0.6827    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6304   -0.1861    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6636   -1.1319    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  2  0  0  0  0
  3  4  1  0  0  0  0
  3  5  1  0  0  0  0
  5  6  2  0  0  0  0
  5  7  1  0  0  0  0
  8  7  1  6  0  0  0
  8  9  1  0  0  0  0
  9 10  1  0  0  0  0
  9 11  2  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 15 14  1  6  0  0  0
 16 15  1  6  0  0  0
 16 17  1  0  0  0  0
 17 18  1  0  0  0  0
 18 19  2  0  0  0  0
 19 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  1  0  0  0  0
 22 24  2  0  0  0  0
 19 25  1  0  0  0  0
 25 26  1  6  0  0  0
 26 27  1  0  0  0  0
 27 28  1  0  0  0  0
 27 29  2  0  0  0  0
 25 30  1  0  0  0  0
  8 30  1  0  0  0  0
 12 30  1  0  0  0  0
 30 31  1  6  0  0  0
 17 32  1  1  0  0  0
 12 32  1  1  0  0  0
 32 33  2  0  0  0  0
 16 34  1  0  0  0  0
 15 34  1  0  0  0  0
 34 35  1  0  0  0  0
 34 36  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0284791

> <DATABASE_NAME>
NP-MRD

> <SMILES>
C\C=C(\C)C(=O)O[C@H]1C(C)=C[C@@]23CC[C@@H]4[C@H]([C@H](C=C(COC(C)=O)[C@@H](OC(C)=O)[C@]12O)C3=O)C4(C)C

> <INCHI_IDENTIFIER>
InChI=1S/C28H36O8/c1-8-14(2)25(32)36-23-15(3)12-27-10-9-20-21(26(20,6)7)19(22(27)31)11-18(13-34-16(4)29)24(28(23,27)33)35-17(5)30/h8,11-12,19-21,23-24,33H,9-10,13H2,1-7H3/b14-8-/t19-,20+,21-,23-,24+,27+,28+/m0/s1

> <INCHI_KEY>
XLPLYIPUTHRBCU-JODHMPKJSA-N

> <FORMULA>
C28H36O8

> <MOLECULAR_WEIGHT>
500.588

> <EXACT_MASS>
500.241018119

> <JCHEM_ACCEPTOR_COUNT>
5

> <JCHEM_ATOM_COUNT>
72

> <JCHEM_AVERAGE_POLARIZABILITY>
53.19277740533631

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
1

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(1S,4S,5R,6R,9S,10R,12R)-6-(acetyloxy)-7-[(acetyloxy)methyl]-5-hydroxy-3,11,11-trimethyl-15-oxotetracyclo[7.5.1.0^{1,5}.0^{10,12}]pentadeca-2,7-dien-4-yl (2Z)-2-methylbut-2-enoate

> <JCHEM_LOGP>
3.1008369853333333

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
4

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
14.950206006462501

> <JCHEM_PKA_STRONGEST_ACIDIC>
12.14140835335201

> <JCHEM_PKA_STRONGEST_BASIC>
-4.048407627444331

> <JCHEM_POLAR_SURFACE_AREA>
116.20000000000002

> <JCHEM_REFRACTIVITY>
131.6111

> <JCHEM_ROTATABLE_BOND_COUNT>
8

> <JCHEM_RULE_OF_FIVE>
0

> <JCHEM_TRADITIONAL_IUPAC>
(1S,4S,5R,6R,9S,10R,12R)-6-(acetyloxy)-7-[(acetyloxy)methyl]-5-hydroxy-3,11,11-trimethyl-15-oxotetracyclo[7.5.1.0^{1,5}.0^{10,12}]pentadeca-2,7-dien-4-yl (2Z)-2-methylbut-2-enoate

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 09-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   09-SEP-22         0                                  
HETATM    1  C   UNK     0      -4.483   2.572   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      -5.847   1.858   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      -5.910   0.319   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      -7.274  -0.396   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      -4.609  -0.505   0.000  0.00  0.00           C+0
HETATM    6  O   UNK     0      -4.673  -2.044   0.000  0.00  0.00           O+0
HETATM    7  O   UNK     0      -3.245   0.209   0.000  0.00  0.00           O+0
HETATM    8  C   UNK     0      -1.944  -0.615   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0      -1.868  -2.161   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0      -3.049  -3.150   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0      -0.360  -2.506   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       0.609  -1.227   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       1.474  -2.633   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       3.005  -3.070   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       4.241  -2.091   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       4.187  -0.552   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       2.956   0.469   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       2.379   1.937   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       0.906   2.474   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0       0.724   4.003   0.000  0.00  0.00           C+0
HETATM   21  O   UNK     0       1.958   4.925   0.000  0.00  0.00           O+0
HETATM   22  C   UNK     0       3.373   4.318   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0       3.555   2.789   0.000  0.00  0.00           C+0
HETATM   24  O   UNK     0       4.606   5.240   0.000  0.00  0.00           O+0
HETATM   25  C   UNK     0      -0.404   1.604   0.000  0.00  0.00           C+0
HETATM   26  O   UNK     0      -1.739   2.373   0.000  0.00  0.00           O+0
HETATM   27  C   UNK     0      -1.740   3.913   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0      -3.075   4.682   0.000  0.00  0.00           C+0
HETATM   29  O   UNK     0      -0.407   4.684   0.000  0.00  0.00           O+0
HETATM   30  C   UNK     0      -0.503  -0.019   0.000  0.00  0.00           C+0
HETATM   31  O   UNK     0      -1.757   0.875   0.000  0.00  0.00           O+0
HETATM   32  C   UNK     0       1.759  -0.401   0.000  0.00  0.00           C+0
HETATM   33  O   UNK     0       2.661  -1.650   0.000  0.00  0.00           O+0
HETATM   34  C   UNK     0       5.547  -1.274   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0       6.777  -0.347   0.000  0.00  0.00           C+0
HETATM   36  C   UNK     0       6.839  -2.113   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4    5                                                  
CONECT    4    3                                                            
CONECT    5    3    6    7                                                  
CONECT    6    5                                                            
CONECT    7    5    8                                                       
CONECT    8    7    9   30                                                  
CONECT    9    8   10   11                                                  
CONECT   10    9                                                            
CONECT   11    9   12                                                       
CONECT   12   11   13   30   32                                             
CONECT   13   12   14                                                       
CONECT   14   13   15                                                       
CONECT   15   14   16   34                                                  
CONECT   16   15   17   34                                                  
CONECT   17   16   18   32                                                  
CONECT   18   17   19                                                       
CONECT   19   18   20   25                                                  
CONECT   20   19   21                                                       
CONECT   21   20   22                                                       
CONECT   22   21   23   24                                                  
CONECT   23   22                                                            
CONECT   24   22                                                            
CONECT   25   19   26   30                                                  
CONECT   26   25   27                                                       
CONECT   27   26   28   29                                                  
CONECT   28   27                                                            
CONECT   29   27                                                            
CONECT   30   25    8   12   31                                             
CONECT   31   30                                                            
CONECT   32   17   12   33                                                  
CONECT   33   32                                                            
CONECT   34   16   15   35   36                                             
CONECT   35   34                                                            
CONECT   36   34                                                            
MASTER        0    0    0    0    0    0    0    0   36    0   78    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₂₈H₃₆O₈

Average Mass

500.5880 Da

Monoisotopic Mass

500.24102 Da

IUPAC Name

Not Available

Traditional Name

Not Available

CAS Registry Number

Not Available

SMILES

C\C=C(\C)C(=O)O[C@H]1C(C)=C[C@@]23CC[C@@H]4[C@H]([C@H](C=C(COC(C)=O)[C@@H](OC(C)=O)[C@]12O)C3=O)C4(C)C

InChI Identifier

InChI=1S/C28H36O8/c1-8-14(2)25(32)36-23-15(3)12-27-10-9-20-21(26(20,6)7)19(22(27)31)11-18(13-34-16(4)29)24(28(23,27)33)35-17(5)30/h8,11-12,19-21,23-24,33H,9-10,13H2,1-7H3/b14-8-/t19-,20+,21-,23-,24+,27+,28+/m0/s1

InChI Key

XLPLYIPUTHRBCU-JODHMPKJSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Euphorbia royleana	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as tricarboxylic acids and derivatives. These are carboxylic acids containing exactly three carboxyl groups.

Kingdom

Organic compounds

Super Class

Organic acids and derivatives

Class

Carboxylic acids and derivatives

Sub Class

Tricarboxylic acids and derivatives

Direct Parent

Tricarboxylic acids and derivatives

Alternative Parents

Substituents

Tricarboxylic acid or derivatives
Fatty acid ester
Fatty acyl
Alpha,beta-unsaturated carboxylic ester
Enoate ester
Tertiary alcohol
Ketone
Carboxylic acid ester
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Carbonyl group
Alcohol
Aliphatic homopolycyclic compound

Molecular Framework

Aliphatic homopolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

24628935

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

45269949

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for (1s,4s,5r,6r,9s,10r,12r)-6-(acetyloxy)-7-[(acetyloxy)methyl]-5-hydroxy-3,11,11-trimethyl-15-oxotetracyclo[7.5.1.0¹,⁵.0¹⁰,¹²]pentadeca-2,7-dien-4-yl (2z)-2-methylbut-2-enoate (NP0284791)

MOL for NP0284791 ((1s,4s,5r,6r,9s,10r,12r)-6-(acetyloxy)-7-[(acetyloxy)methyl]-5-hydroxy-3,11,11-trimethyl-15-oxotetracyclo[7.5.1.0¹,⁵.0¹⁰,¹²]pentadeca-2,7-dien-4-yl (2z)-2-methylbut-2-enoate)

3D MOL for NP0284791 ((1s,4s,5r,6r,9s,10r,12r)-6-(acetyloxy)-7-[(acetyloxy)methyl]-5-hydroxy-3,11,11-trimethyl-15-oxotetracyclo[7.5.1.0¹,⁵.0¹⁰,¹²]pentadeca-2,7-dien-4-yl (2z)-2-methylbut-2-enoate)

3D SDF for NP0284791 ((1s,4s,5r,6r,9s,10r,12r)-6-(acetyloxy)-7-[(acetyloxy)methyl]-5-hydroxy-3,11,11-trimethyl-15-oxotetracyclo[7.5.1.0¹,⁵.0¹⁰,¹²]pentadeca-2,7-dien-4-yl (2z)-2-methylbut-2-enoate)

3D-SDF for NP0284791 ((1s,4s,5r,6r,9s,10r,12r)-6-(acetyloxy)-7-[(acetyloxy)methyl]-5-hydroxy-3,11,11-trimethyl-15-oxotetracyclo[7.5.1.0¹,⁵.0¹⁰,¹²]pentadeca-2,7-dien-4-yl (2z)-2-methylbut-2-enoate)

PDB for NP0284791 ((1s,4s,5r,6r,9s,10r,12r)-6-(acetyloxy)-7-[(acetyloxy)methyl]-5-hydroxy-3,11,11-trimethyl-15-oxotetracyclo[7.5.1.0¹,⁵.0¹⁰,¹²]pentadeca-2,7-dien-4-yl (2z)-2-methylbut-2-enoate)

3D PDB for NP0284791 ((1s,4s,5r,6r,9s,10r,12r)-6-(acetyloxy)-7-[(acetyloxy)methyl]-5-hydroxy-3,11,11-trimethyl-15-oxotetracyclo[7.5.1.0¹,⁵.0¹⁰,¹²]pentadeca-2,7-dien-4-yl (2z)-2-methylbut-2-enoate)

SMILES for NP0284791 ((1s,4s,5r,6r,9s,10r,12r)-6-(acetyloxy)-7-[(acetyloxy)methyl]-5-hydroxy-3,11,11-trimethyl-15-oxotetracyclo[7.5.1.0¹,⁵.0¹⁰,¹²]pentadeca-2,7-dien-4-yl (2z)-2-methylbut-2-enoate)

INCHI for NP0284791 ((1s,4s,5r,6r,9s,10r,12r)-6-(acetyloxy)-7-[(acetyloxy)methyl]-5-hydroxy-3,11,11-trimethyl-15-oxotetracyclo[7.5.1.0¹,⁵.0¹⁰,¹²]pentadeca-2,7-dien-4-yl (2z)-2-methylbut-2-enoate)

Structure for NP0284791 ((1s,4s,5r,6r,9s,10r,12r)-6-(acetyloxy)-7-[(acetyloxy)methyl]-5-hydroxy-3,11,11-trimethyl-15-oxotetracyclo[7.5.1.0¹,⁵.0¹⁰,¹²]pentadeca-2,7-dien-4-yl (2z)-2-methylbut-2-enoate)

3D Structure for NP0284791 ((1s,4s,5r,6r,9s,10r,12r)-6-(acetyloxy)-7-[(acetyloxy)methyl]-5-hydroxy-3,11,11-trimethyl-15-oxotetracyclo[7.5.1.0¹,⁵.0¹⁰,¹²]pentadeca-2,7-dien-4-yl (2z)-2-methylbut-2-enoate)