NP-MRD: Showing NP-Card for 1,3a,5-trihydroxy-1-(1-{2-hydroxy-1,2,6-trimethyl-3,7-dioxabicyclo[4.1.0]heptan-4-yl}ethyl)-9a,11a-dimethyl-2h,3h,3bh,4h,5h,9bh,10h,11h-cyclopenta[a]phenanthren-9-one (NP0282840)

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Record Information

Version

2.0

Created at

2022-09-09 09:50:11 UTC

Updated at

2022-09-09 09:50:12 UTC

NP-MRD ID

NP0282840

Secondary Accession Numbers

None

Natural Product Identification

Common Name

1,3a,5-trihydroxy-1-(1-{2-hydroxy-1,2,6-trimethyl-3,7-dioxabicyclo[4.1.0]heptan-4-yl}ethyl)-9a,11a-dimethyl-2h,3h,3bh,4h,5h,9bh,10h,11h-cyclopenta[a]phenanthren-9-one

Description

8,11,14-Trihydroxy-14-(1-{2-hydroxy-1,2,6-trimethyl-3,7-dioxabicyclo[4.1.0]Heptan-4-yl}ethyl)-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]Heptadeca-4,6-dien-3-one belongs to the class of organic compounds known as oxosteroids. These are steroid derivatives carrying a C=O group attached to steroid skeleton. 1,3a,5-trihydroxy-1-(1-{2-hydroxy-1,2,6-trimethyl-3,7-dioxabicyclo[4.1.0]heptan-4-yl}ethyl)-9a,11a-dimethyl-2h,3h,3bh,4h,5h,9bh,10h,11h-cyclopenta[a]phenanthren-9-one is found in Jaborosa bergii. 8,11,14-Trihydroxy-14-(1-{2-hydroxy-1,2,6-trimethyl-3,7-dioxabicyclo[4.1.0]Heptan-4-yl}ethyl)-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]Heptadeca-4,6-dien-3-one is an extremely weak basic (essentially neutral) compound (based on its pKa).

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1533004231514252D          

 36 41  0  0  0  0            999 V2000
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M  END

     RDKit          3D

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M  END


  Mrv1533004231514252D          

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    7.6731   -2.5662    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.8610   -2.7114    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.5807   -3.4873    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.3292   -2.0807    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0489   -2.8566    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.5171   -2.2259    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2368   -3.0018    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4247   -3.1470    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.8928   -2.5163    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5330   -3.2587    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  1  0  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  5  7  1  0  0  0  0
  7  8  1  0  0  0  0
  5  8  1  0  0  0  0
  8  9  1  0  0  0  0
  8 10  1  0  0  0  0
 10 11  1  0  0  0  0
 10 12  1  0  0  0  0
 10 13  1  0  0  0  0
  3 13  1  0  0  0  0
  2 14  1  0  0  0  0
 14 15  1  0  0  0  0
 14 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  1  0  0  0  0
 18 19  1  0  0  0  0
 18 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  1  0  0  0  0
 22 24  1  0  0  0  0
 24 25  2  0  0  0  0
 25 26  1  0  0  0  0
 26 27  2  0  0  0  0
 27 28  1  0  0  0  0
 28 29  2  0  0  0  0
 28 30  1  0  0  0  0
 24 30  1  0  0  0  0
 30 31  1  0  0  0  0
 30 32  1  0  0  0  0
 20 32  1  0  0  0  0
 32 33  1  0  0  0  0
 33 34  1  0  0  0  0
 34 35  1  0  0  0  0
 14 35  1  0  0  0  0
 18 35  1  0  0  0  0
 35 36  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0282840

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CC(C1CC2(C)OC2(C)C(C)(O)O1)C1(O)CCC2(O)C3CC(O)C4=CC=CC(=O)C4(C)C3CCC12C

> <INCHI_IDENTIFIER>
InChI=1S/C29H42O7/c1-16(21-15-24(3)26(5,36-24)27(6,32)35-21)28(33)12-13-29(34)19-14-20(30)18-8-7-9-22(31)25(18,4)17(19)10-11-23(28,29)2/h7-9,16-17,19-21,30,32-34H,10-15H2,1-6H3

> <INCHI_KEY>
RKFCLQILUORBKT-UHFFFAOYSA-N

> <FORMULA>
C29H42O7

> <MOLECULAR_WEIGHT>
502.648

> <EXACT_MASS>
502.293053692

> <JCHEM_ACCEPTOR_COUNT>
7

> <JCHEM_ATOM_COUNT>
78

> <JCHEM_AVERAGE_POLARIZABILITY>
55.534609669041686

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
4

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
8,11,14-trihydroxy-14-(1-{2-hydroxy-1,2,6-trimethyl-3,7-dioxabicyclo[4.1.0]heptan-4-yl}ethyl)-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-4,6-dien-3-one

> <ALOGPS_LOGP>
2.05

> <JCHEM_LOGP>
1.9135830813333343

> <ALOGPS_LOGS>
-3.73

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
6

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
13.691644314893537

> <JCHEM_PKA_STRONGEST_ACIDIC>
11.087854109487312

> <JCHEM_PKA_STRONGEST_BASIC>
-2.991857380114997

> <JCHEM_POLAR_SURFACE_AREA>
119.75

> <JCHEM_REFRACTIVITY>
135.0893

> <JCHEM_ROTATABLE_BOND_COUNT>
2

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
9.34e-02 g/l

> <JCHEM_TRADITIONAL_IUPAC>
8,11,14-trihydroxy-14-(1-{2-hydroxy-1,2,6-trimethyl-3,7-dioxabicyclo[4.1.0]heptan-4-yl}ethyl)-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-4,6-dien-3-one

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 23-APR-15   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   23-APR-15         0                                  
HETATM    1  C   UNK     0       3.688  -6.367   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       4.211  -4.918   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       3.219  -3.741   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       1.703  -4.012   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       0.710  -2.835   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0      -0.467  -3.827   0.000  0.00  0.00           C+0
HETATM    7  O   UNK     0      -0.283  -1.657   0.000  0.00  0.00           O+0
HETATM    8  C   UNK     0       1.233  -1.386   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       0.962   0.130   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       2.749  -1.115   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       2.219   0.331   0.000  0.00  0.00           C+0
HETATM   12  O   UNK     0       4.081  -0.342   0.000  0.00  0.00           O+0
HETATM   13  O   UNK     0       3.742  -2.292   0.000  0.00  0.00           O+0
HETATM   14  C   UNK     0       5.727  -4.647   0.000  0.00  0.00           C+0
HETATM   15  O   UNK     0       5.839  -6.183   0.000  0.00  0.00           O+0
HETATM   16  C   UNK     0       5.299  -3.168   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       6.574  -2.304   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       7.790  -3.249   0.000  0.00  0.00           C+0
HETATM   19  O   UNK     0       8.159  -1.754   0.000  0.00  0.00           O+0
HETATM   20  C   UNK     0       9.306  -2.978   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0       9.829  -1.529   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0      11.345  -1.258   0.000  0.00  0.00           C+0
HETATM   23  O   UNK     0      11.868   0.190   0.000  0.00  0.00           O+0
HETATM   24  C   UNK     0      12.338  -2.436   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0      13.854  -2.164   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0      14.846  -3.342   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0      14.323  -4.790   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0      12.807  -5.061   0.000  0.00  0.00           C+0
HETATM   29  O   UNK     0      12.284  -6.510   0.000  0.00  0.00           O+0
HETATM   30  C   UNK     0      11.814  -3.884   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0      11.291  -5.332   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0      10.299  -4.155   0.000  0.00  0.00           C+0
HETATM   33  C   UNK     0       9.775  -5.603   0.000  0.00  0.00           C+0
HETATM   34  C   UNK     0       8.259  -5.874   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0       7.267  -4.697   0.000  0.00  0.00           C+0
HETATM   36  C   UNK     0       6.595  -6.083   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3   14                                                  
CONECT    3    2    4   13                                                  
CONECT    4    3    5                                                       
CONECT    5    4    6    7    8                                             
CONECT    6    5                                                            
CONECT    7    5    8                                                       
CONECT    8    7    5    9   10                                             
CONECT    9    8                                                            
CONECT   10    8   11   12   13                                             
CONECT   11   10                                                            
CONECT   12   10                                                            
CONECT   13   10    3                                                       
CONECT   14    2   15   16   35                                             
CONECT   15   14                                                            
CONECT   16   14   17                                                       
CONECT   17   16   18                                                       
CONECT   18   17   19   20   35                                             
CONECT   19   18                                                            
CONECT   20   18   21   32                                                  
CONECT   21   20   22                                                       
CONECT   22   21   23   24                                                  
CONECT   23   22                                                            
CONECT   24   22   25   30                                                  
CONECT   25   24   26                                                       
CONECT   26   25   27                                                       
CONECT   27   26   28                                                       
CONECT   28   27   29   30                                                  
CONECT   29   28                                                            
CONECT   30   28   24   31   32                                             
CONECT   31   30                                                            
CONECT   32   30   20   33                                                  
CONECT   33   32   34                                                       
CONECT   34   33   35                                                       
CONECT   35   34   14   18   36                                             
CONECT   36   35                                                            
MASTER        0    0    0    0    0    0    0    0   36    0   82    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₂₉H₄₂O₇

Average Mass

502.6480 Da

Monoisotopic Mass

502.29305 Da

IUPAC Name

8,11,14-trihydroxy-14-(1-{2-hydroxy-1,2,6-trimethyl-3,7-dioxabicyclo[4.1.0]heptan-4-yl}ethyl)-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-4,6-dien-3-one

Traditional Name

8,11,14-trihydroxy-14-(1-{2-hydroxy-1,2,6-trimethyl-3,7-dioxabicyclo[4.1.0]heptan-4-yl}ethyl)-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-4,6-dien-3-one

CAS Registry Number

Not Available

SMILES

CC(C1CC2(C)OC2(C)C(C)(O)O1)C1(O)CCC2(O)C3CC(O)C4=CC=CC(=O)C4(C)C3CCC12C

InChI Identifier

InChI=1S/C29H42O7/c1-16(21-15-24(3)26(5,36-24)27(6,32)35-21)28(33)12-13-29(34)19-14-20(30)18-8-7-9-22(31)25(18,4)17(19)10-11-23(28,29)2/h7-9,16-17,19-21,30,32-34H,10-15H2,1-6H3

InChI Key

RKFCLQILUORBKT-UHFFFAOYSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Jaborosa bergii	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as oxosteroids. These are steroid derivatives carrying a C=O group attached to steroid skeleton.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Steroids and steroid derivatives

Sub Class

Oxosteroids

Direct Parent

Oxosteroids

Alternative Parents

Substituents

27-hydroxysteroid
Pregnane-skeleton
14-hydroxysteroid
6-hydroxysteroid
17-hydroxysteroid
Hydroxysteroid
Oxosteroid
1-oxosteroid
1,4-dioxepane
Dioxepane
Oxane
Cyclic alcohol
Tertiary alcohol
Hemiacetal
Secondary alcohol
Ketone
Organoheterocyclic compound
Oxacycle
Ether
Oxirane
Dialkyl ether
Polyol
Alcohol
Organic oxygen compound
Hydrocarbon derivative
Organic oxide
Carbonyl group
Organooxygen compound
Aliphatic heteropolycyclic compound

Molecular Framework

Aliphatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	2.05	ALOGPS
logP	1.91	ChemAxon
logS	-3.7	ALOGPS
pKa (Strongest Acidic)	11.09	ChemAxon
pKa (Strongest Basic)	-3	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	7	ChemAxon
Hydrogen Donor Count	4	ChemAxon
Polar Surface Area	119.75 Å²	ChemAxon
Rotatable Bond Count	2	ChemAxon
Refractivity	135.09 m³·mol⁻¹	ChemAxon
Polarizability	55.53 Å³	ChemAxon
Number of Rings	6	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

14188970

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for 1,3a,5-trihydroxy-1-(1-{2-hydroxy-1,2,6-trimethyl-3,7-dioxabicyclo[4.1.0]heptan-4-yl}ethyl)-9a,11a-dimethyl-2h,3h,3bh,4h,5h,9bh,10h,11h-cyclopenta[a]phenanthren-9-one (NP0282840)

MOL for NP0282840 (1,3a,5-trihydroxy-1-(1-{2-hydroxy-1,2,6-trimethyl-3,7-dioxabicyclo[4.1.0]heptan-4-yl}ethyl)-9a,11a-dimethyl-2h,3h,3bh,4h,5h,9bh,10h,11h-cyclopenta[a]phenanthren-9-one)

3D MOL for NP0282840 (1,3a,5-trihydroxy-1-(1-{2-hydroxy-1,2,6-trimethyl-3,7-dioxabicyclo[4.1.0]heptan-4-yl}ethyl)-9a,11a-dimethyl-2h,3h,3bh,4h,5h,9bh,10h,11h-cyclopenta[a]phenanthren-9-one)

3D SDF for NP0282840 (1,3a,5-trihydroxy-1-(1-{2-hydroxy-1,2,6-trimethyl-3,7-dioxabicyclo[4.1.0]heptan-4-yl}ethyl)-9a,11a-dimethyl-2h,3h,3bh,4h,5h,9bh,10h,11h-cyclopenta[a]phenanthren-9-one)

3D-SDF for NP0282840 (1,3a,5-trihydroxy-1-(1-{2-hydroxy-1,2,6-trimethyl-3,7-dioxabicyclo[4.1.0]heptan-4-yl}ethyl)-9a,11a-dimethyl-2h,3h,3bh,4h,5h,9bh,10h,11h-cyclopenta[a]phenanthren-9-one)

PDB for NP0282840 (1,3a,5-trihydroxy-1-(1-{2-hydroxy-1,2,6-trimethyl-3,7-dioxabicyclo[4.1.0]heptan-4-yl}ethyl)-9a,11a-dimethyl-2h,3h,3bh,4h,5h,9bh,10h,11h-cyclopenta[a]phenanthren-9-one)

3D PDB for NP0282840 (1,3a,5-trihydroxy-1-(1-{2-hydroxy-1,2,6-trimethyl-3,7-dioxabicyclo[4.1.0]heptan-4-yl}ethyl)-9a,11a-dimethyl-2h,3h,3bh,4h,5h,9bh,10h,11h-cyclopenta[a]phenanthren-9-one)

SMILES for NP0282840 (1,3a,5-trihydroxy-1-(1-{2-hydroxy-1,2,6-trimethyl-3,7-dioxabicyclo[4.1.0]heptan-4-yl}ethyl)-9a,11a-dimethyl-2h,3h,3bh,4h,5h,9bh,10h,11h-cyclopenta[a]phenanthren-9-one)

INCHI for NP0282840 (1,3a,5-trihydroxy-1-(1-{2-hydroxy-1,2,6-trimethyl-3,7-dioxabicyclo[4.1.0]heptan-4-yl}ethyl)-9a,11a-dimethyl-2h,3h,3bh,4h,5h,9bh,10h,11h-cyclopenta[a]phenanthren-9-one)

Structure for NP0282840 (1,3a,5-trihydroxy-1-(1-{2-hydroxy-1,2,6-trimethyl-3,7-dioxabicyclo[4.1.0]heptan-4-yl}ethyl)-9a,11a-dimethyl-2h,3h,3bh,4h,5h,9bh,10h,11h-cyclopenta[a]phenanthren-9-one)

3D Structure for NP0282840 (1,3a,5-trihydroxy-1-(1-{2-hydroxy-1,2,6-trimethyl-3,7-dioxabicyclo[4.1.0]heptan-4-yl}ethyl)-9a,11a-dimethyl-2h,3h,3bh,4h,5h,9bh,10h,11h-cyclopenta[a]phenanthren-9-one)