NP-MRD: Showing NP-Card for 4-{6-[5-(dimethylamino)-6-methyloxan-2-yl]-1,5-dihydroxy-9,10-dioxoanthracen-2-yl}-3-hydroxy-3-methylbutanoic acid (NP0280962)

Jump To Section:

Identification Spectra BioTaxonomy ChemoTaxonomy Physical properties Links References XML

Record Information

Version

2.0

Created at

2022-09-09 07:02:25 UTC

Updated at

2022-09-09 07:02:25 UTC

NP-MRD ID

NP0280962

Secondary Accession Numbers

None

Natural Product Identification

Common Name

4-{6-[5-(dimethylamino)-6-methyloxan-2-yl]-1,5-dihydroxy-9,10-dioxoanthracen-2-yl}-3-hydroxy-3-methylbutanoic acid

Description

4-{6-[5-(Dimethylamino)-6-methyloxan-2-yl]-1,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracen-2-yl}-3-hydroxy-3-methylbutanoic acid belongs to the class of organic compounds known as anthraquinones. These are organic compounds containing either anthracene-9,10-quinone, 1,4-anthraquinone, or 1,2-anthraquinone. Based on a literature review very few articles have been published on 4-{6-[5-(dimethylamino)-6-methyloxan-2-yl]-1,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracen-2-yl}-3-hydroxy-3-methylbutanoic acid.

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652309092209022D          

 36 39  0  0  0  0            999 V2000
    5.7158   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5395    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1105    2.0625    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    2.8875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289    3.3000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289    4.1250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1434    2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    2.0625    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434    2.0625    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4302   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4302   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.1447   -1.6500    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    7.8592   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.1447   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  1  0  0  0  0
  4  5  1  0  0  0  0
  5  6  2  0  0  0  0
  6  7  1  0  0  0  0
  7  8  2  0  0  0  0
  8  9  1  0  0  0  0
  9 10  2  0  0  0  0
  5 10  1  0  0  0  0
 10 11  1  0  0  0  0
  9 12  1  0  0  0  0
 12 13  2  0  0  0  0
 12 14  1  0  0  0  0
 14 15  2  0  0  0  0
 15 16  1  0  0  0  0
 16 17  2  0  0  0  0
 17 18  1  0  0  0  0
 18 19  1  0  0  0  0
 19 20  1  0  0  0  0
 19 21  1  0  0  0  0
 19 22  1  0  0  0  0
 22 23  1  0  0  0  0
 23 24  2  0  0  0  0
 23 25  1  0  0  0  0
 17 26  1  0  0  0  0
 26 27  1  0  0  0  0
 26 28  2  0  0  0  0
 14 28  1  0  0  0  0
 28 29  1  0  0  0  0
  8 29  1  0  0  0  0
 29 30  2  0  0  0  0
  4 31  1  0  0  0  0
 31 32  1  0  0  0  0
 32 33  1  0  0  0  0
  2 33  1  0  0  0  0
 33 34  1  0  0  0  0
 34 35  1  0  0  0  0
 34 36  1  0  0  0  0
M  END

     RDKit          3D

 67 70  0  0  0  0  0  0  0  0999 V2000
    5.1682   -1.9125    0.4815 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.1333   -0.4799    0.8854 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.9337    0.1774    0.6144 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.5976   -0.1209   -0.6866 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.1854    0.2027   -0.9065 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6989    0.6025   -2.0969 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3655    0.8982   -2.3126 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4830    0.7618   -1.2097 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0472    0.3594    0.0292 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3035    0.0726    0.1901 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7908   -0.3309    1.3844 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9755    0.2527    1.1422 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6280   -0.1073    2.2785 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3943    0.5794    0.9368 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2760    0.4833    1.9971 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6051    0.7825    1.8408 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.0879    1.1857    0.6203 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.5313    1.4773    0.3983 C   0  0  0  0  0  0  0  0  0  0  0  0
   -7.1963    0.2610   -0.2600 C   0  0  1  0  0  0  0  0  0  0  0  0
   -8.6561    0.5878   -0.4515 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.6524   -0.0331   -1.4861 O   0  0  0  0  0  0  0  0  0  0  0  0
   -7.0571   -0.9400    0.6302 C   0  0  0  0  0  0  0  0  0  0  0  0
   -7.6598   -2.1546    0.0445 C   0  0  0  0  0  0  0  0  0  0  0  0
   -8.1884   -2.1677   -1.0996 O   0  0  0  0  0  0  0  0  0  0  0  0
   -7.6600   -3.3535    0.7602 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1799    1.2813   -0.4525 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6712    1.6865   -1.6659 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8434    0.9815   -0.2948 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9015    1.0856   -1.4074 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2354    1.4442   -2.5584 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.5325    0.3500   -1.7395 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9516    0.4046   -1.3159 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.2497    0.2436    0.1284 C   0  0  2  0  0  0  0  0  0  0  0  0
    7.4717   -0.4228    0.4446 N   0  0  0  0  0  0  0  0  0  0  0  0
    7.8639   -0.3732    1.8140 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.5227   -0.2457   -0.4983 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.5036   -2.0311   -0.5892 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.2875   -2.5112    0.7206 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.0355   -2.3738    1.0477 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.3314   -0.3938    1.9519 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.6443   -1.2623   -0.7414 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.3263    0.7270   -2.9930 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.0026    1.2220   -3.2811 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.4129   -0.4937    2.2442 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9240    0.1681    2.9828 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3322    0.7210    2.6492 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.0379    1.6499    1.3443 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.6143    2.3304   -0.2686 H   0  0  0  0  0  0  0  0  0  0  0  0
   -8.7523    1.5913   -0.9474 H   0  0  0  0  0  0  0  0  0  0  0  0
   -9.1721    0.6935    0.5405 H   0  0  0  0  0  0  0  0  0  0  0  0
   -9.2119   -0.1207   -1.0648 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.0227   -0.7727   -1.3968 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.5589   -0.7526    1.5994 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.9668   -1.1455    0.7629 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.9043   -4.0312    0.5712 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.2680    1.8228   -2.5007 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.4597   -0.3759   -2.6115 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.2195    1.3176   -2.2046 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.5473   -0.3820   -1.8612 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.3524    1.4299   -1.6142 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.2685    1.2801    0.6000 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.1829    0.1342    2.5016 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.9726   -1.4136    2.1898 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.8861    0.1028    1.8934 H   0  0  0  0  0  0  0  0  0  0  0  0
    9.4904   -0.4175    0.0155 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.4256   -0.9952   -1.3021 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.5771    0.7622   -0.9381 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  1  0
  4 31  1  0
 31 32  1  0
 32 33  1  0
 33 34  1  0
 34 35  1  0
 34 36  1  0
  4  5  1  0
  5  6  2  0
  6  7  1  0
  7  8  2  0
  8 29  1  0
 29 30  2  0
 29 28  1  0
 28 26  2  0
 26 27  1  0
 26 17  1  0
 17 18  1  0
 18 19  1  0
 19 20  1  0
 19 21  1  6
 19 22  1  0
 22 23  1  0
 23 25  1  0
 23 24  2  0
 17 16  2  0
 16 15  1  0
 15 14  2  0
 14 12  1  0
 12 13  2  0
 12  9  1  0
  9 10  2  0
 10 11  1  0
 33  2  1  0
 10  5  1  0
  9  8  1  0
 14 28  1  0
  1 37  1  0
  1 38  1  0
  1 39  1  0
  2 40  1  1
  4 41  1  1
 31 57  1  0
 31 58  1  0
 32 59  1  0
 32 60  1  0
 33 61  1  1
 35 62  1  0
 35 63  1  0
 35 64  1  0
 36 65  1  0
 36 66  1  0
 36 67  1  0
  6 42  1  0
  7 43  1  0
 27 56  1  0
 18 47  1  0
 18 48  1  0
 20 49  1  0
 20 50  1  0
 20 51  1  0
 21 52  1  0
 22 53  1  0
 22 54  1  0
 25 55  1  0
 16 46  1  0
 15 45  1  0
 11 44  1  0
M  END


  Mrv1652309092209022D          

 36 39  0  0  0  0            999 V2000
    5.7158   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5395    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1105    2.0625    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    2.8875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289    3.3000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289    4.1250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1434    2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    2.0625    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434    2.0625    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4302   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4302   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.1447   -1.6500    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    7.8592   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.1447   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  1  0  0  0  0
  4  5  1  0  0  0  0
  5  6  2  0  0  0  0
  6  7  1  0  0  0  0
  7  8  2  0  0  0  0
  8  9  1  0  0  0  0
  9 10  2  0  0  0  0
  5 10  1  0  0  0  0
 10 11  1  0  0  0  0
  9 12  1  0  0  0  0
 12 13  2  0  0  0  0
 12 14  1  0  0  0  0
 14 15  2  0  0  0  0
 15 16  1  0  0  0  0
 16 17  2  0  0  0  0
 17 18  1  0  0  0  0
 18 19  1  0  0  0  0
 19 20  1  0  0  0  0
 19 21  1  0  0  0  0
 19 22  1  0  0  0  0
 22 23  1  0  0  0  0
 23 24  2  0  0  0  0
 23 25  1  0  0  0  0
 17 26  1  0  0  0  0
 26 27  1  0  0  0  0
 26 28  2  0  0  0  0
 14 28  1  0  0  0  0
 28 29  1  0  0  0  0
  8 29  1  0  0  0  0
 29 30  2  0  0  0  0
  4 31  1  0  0  0  0
 31 32  1  0  0  0  0
 32 33  1  0  0  0  0
  2 33  1  0  0  0  0
 33 34  1  0  0  0  0
 34 35  1  0  0  0  0
 34 36  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0280962

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CC1OC(CCC1N(C)C)C1=CC=C2C(=O)C3=C(O)C(CC(C)(O)CC(O)=O)=CC=C3C(=O)C2=C1O

> <INCHI_IDENTIFIER>
InChI=1S/C27H31NO8/c1-13-18(28(3)4)9-10-19(36-13)15-7-8-17-22(24(15)32)26(34)16-6-5-14(23(31)21(16)25(17)33)11-27(2,35)12-20(29)30/h5-8,13,18-19,31-32,35H,9-12H2,1-4H3,(H,29,30)

> <INCHI_KEY>
SRYOJNZDZIEUBQ-UHFFFAOYSA-N

> <FORMULA>
C27H31NO8

> <MOLECULAR_WEIGHT>
497.544

> <EXACT_MASS>
497.204966962

> <JCHEM_ACCEPTOR_COUNT>
9

> <JCHEM_ATOM_COUNT>
67

> <JCHEM_AVERAGE_POLARIZABILITY>
53.3975753248972

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
4

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
4-{6-[5-(dimethylamino)-6-methyloxan-2-yl]-1,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracen-2-yl}-3-hydroxy-3-methylbutanoic acid

> <JCHEM_LOGP>
1.2919912655833934

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
4

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
7.409264555038355

> <JCHEM_PKA_STRONGEST_ACIDIC>
2.9354438948782797

> <JCHEM_PKA_STRONGEST_BASIC>
7.9017912807160595

> <JCHEM_POLAR_SURFACE_AREA>
144.60000000000002

> <JCHEM_REFRACTIVITY>
132.66249999999994

> <JCHEM_ROTATABLE_BOND_COUNT>
6

> <JCHEM_RULE_OF_FIVE>
1

> <JCHEM_TRADITIONAL_IUPAC>
4-{6-[5-(dimethylamino)-6-methyloxan-2-yl]-1,5-dihydroxy-9,10-dioxoanthracen-2-yl}-3-hydroxy-3-methylbutanoic acid

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 09-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   09-SEP-22         0                                  
HETATM    1  C   UNK     0      10.669  -4.620   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      10.669  -3.080   0.000  0.00  0.00           C+0
HETATM    3  O   UNK     0       9.336  -2.310   0.000  0.00  0.00           O+0
HETATM    4  C   UNK     0       9.336  -0.770   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       8.002  -0.000   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       8.002   1.540   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       6.668   2.310   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       5.335   1.540   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       5.335   0.000   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       6.668  -0.770   0.000  0.00  0.00           C+0
HETATM   11  O   UNK     0       6.668  -2.310   0.000  0.00  0.00           O+0
HETATM   12  C   UNK     0       4.001  -0.770   0.000  0.00  0.00           C+0
HETATM   13  O   UNK     0       4.001  -2.310   0.000  0.00  0.00           O+0
HETATM   14  C   UNK     0       2.667  -0.000   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       1.334  -0.770   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0      -0.000   0.000   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       0.000   1.540   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0      -1.334   2.310   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0      -1.334   3.850   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0      -2.874   3.850   0.000  0.00  0.00           C+0
HETATM   21  O   UNK     0       0.206   3.850   0.000  0.00  0.00           O+0
HETATM   22  C   UNK     0      -1.334   5.390   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0      -2.667   6.160   0.000  0.00  0.00           C+0
HETATM   24  O   UNK     0      -2.667   7.700   0.000  0.00  0.00           O+0
HETATM   25  O   UNK     0      -4.001   5.390   0.000  0.00  0.00           O+0
HETATM   26  C   UNK     0       1.334   2.310   0.000  0.00  0.00           C+0
HETATM   27  O   UNK     0       1.334   3.850   0.000  0.00  0.00           O+0
HETATM   28  C   UNK     0       2.667   1.540   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0       4.001   2.310   0.000  0.00  0.00           C+0
HETATM   30  O   UNK     0       4.001   3.850   0.000  0.00  0.00           O+0
HETATM   31  C   UNK     0      10.669  -0.000   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0      12.003  -0.770   0.000  0.00  0.00           C+0
HETATM   33  C   UNK     0      12.003  -2.310   0.000  0.00  0.00           C+0
HETATM   34  N   UNK     0      13.337  -3.080   0.000  0.00  0.00           N+0
HETATM   35  C   UNK     0      14.670  -2.310   0.000  0.00  0.00           C+0
HETATM   36  C   UNK     0      13.337  -4.620   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3   33                                                  
CONECT    3    2    4                                                       
CONECT    4    3    5   31                                                  
CONECT    5    4    6   10                                                  
CONECT    6    5    7                                                       
CONECT    7    6    8                                                       
CONECT    8    7    9   29                                                  
CONECT    9    8   10   12                                                  
CONECT   10    9    5   11                                                  
CONECT   11   10                                                            
CONECT   12    9   13   14                                                  
CONECT   13   12                                                            
CONECT   14   12   15   28                                                  
CONECT   15   14   16                                                       
CONECT   16   15   17                                                       
CONECT   17   16   18   26                                                  
CONECT   18   17   19                                                       
CONECT   19   18   20   21   22                                             
CONECT   20   19                                                            
CONECT   21   19                                                            
CONECT   22   19   23                                                       
CONECT   23   22   24   25                                                  
CONECT   24   23                                                            
CONECT   25   23                                                            
CONECT   26   17   27   28                                                  
CONECT   27   26                                                            
CONECT   28   26   14   29                                                  
CONECT   29   28    8   30                                                  
CONECT   30   29                                                            
CONECT   31    4   32                                                       
CONECT   32   31   33                                                       
CONECT   33   32    2   34                                                  
CONECT   34   33   35   36                                                  
CONECT   35   34                                                            
CONECT   36   34                                                            
MASTER        0    0    0    0    0    0    0    0   36    0   78    0
END

View in JSmol

Synonyms

Value	Source
4-{6-[5-(dimethylamino)-6-methyloxan-2-yl]-1,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracen-2-yl}-3-hydroxy-3-methylbutanoate	Generator

Chemical Formula

C₂₇H₃₁NO₈

Average Mass

497.5440 Da

Monoisotopic Mass

497.20497 Da

IUPAC Name

4-{6-[5-(dimethylamino)-6-methyloxan-2-yl]-1,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracen-2-yl}-3-hydroxy-3-methylbutanoic acid

Traditional Name

4-{6-[5-(dimethylamino)-6-methyloxan-2-yl]-1,5-dihydroxy-9,10-dioxoanthracen-2-yl}-3-hydroxy-3-methylbutanoic acid

CAS Registry Number

Not Available

SMILES

CC1OC(CCC1N(C)C)C1=CC=C2C(=O)C3=C(O)C(CC(C)(O)CC(O)=O)=CC=C3C(=O)C2=C1O

InChI Identifier

InChI=1S/C27H31NO8/c1-13-18(28(3)4)9-10-19(36-13)15-7-8-17-22(24(15)32)26(34)16-6-5-14(23(31)21(16)25(17)33)11-27(2,35)12-20(29)30/h5-8,13,18-19,31-32,35H,9-12H2,1-4H3,(H,29,30)

InChI Key

SRYOJNZDZIEUBQ-UHFFFAOYSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Not Available

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as anthraquinones. These are organic compounds containing either anthracene-9,10-quinone, 1,4-anthraquinone, or 1,2-anthraquinone.

Kingdom

Super Class

Class

Sub Class

Direct Parent

Alternative Parents

Substituents

Anthraquinone
9,10-anthraquinone
Aryl ketone
1-hydroxy-4-unsubstituted benzenoid
Aralkylamine
Oxane
Vinylogous acid
Tertiary alcohol
Amino acid
Tertiary aliphatic amine
Tertiary amine
Ketone
Amino acid or derivatives
Oxacycle
Organoheterocyclic compound
Monocarboxylic acid or derivatives
Ether
Dialkyl ether
Carboxylic acid
Carboxylic acid derivative
Organic nitrogen compound
Organic oxygen compound
Organopnictogen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Organonitrogen compound
Carbonyl group
Amine
Alcohol
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	1.29	ChemAxon
pKa (Strongest Acidic)	2.94	ChemAxon
pKa (Strongest Basic)	7.9	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	9	ChemAxon
Hydrogen Donor Count	4	ChemAxon
Polar Surface Area	144.6 Å²	ChemAxon
Rotatable Bond Count	6	ChemAxon
Refractivity	132.66 m³·mol⁻¹	ChemAxon
Polarizability	53.4 Å³	ChemAxon
Number of Rings	4	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	Yes	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

163073234

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for 4-{6-[5-(dimethylamino)-6-methyloxan-2-yl]-1,5-dihydroxy-9,10-dioxoanthracen-2-yl}-3-hydroxy-3-methylbutanoic acid (NP0280962)

MOL for NP0280962 (4-{6-[5-(dimethylamino)-6-methyloxan-2-yl]-1,5-dihydroxy-9,10-dioxoanthracen-2-yl}-3-hydroxy-3-methylbutanoic acid)

3D MOL for NP0280962 (4-{6-[5-(dimethylamino)-6-methyloxan-2-yl]-1,5-dihydroxy-9,10-dioxoanthracen-2-yl}-3-hydroxy-3-methylbutanoic acid)

3D SDF for NP0280962 (4-{6-[5-(dimethylamino)-6-methyloxan-2-yl]-1,5-dihydroxy-9,10-dioxoanthracen-2-yl}-3-hydroxy-3-methylbutanoic acid)

3D-SDF for NP0280962 (4-{6-[5-(dimethylamino)-6-methyloxan-2-yl]-1,5-dihydroxy-9,10-dioxoanthracen-2-yl}-3-hydroxy-3-methylbutanoic acid)

PDB for NP0280962 (4-{6-[5-(dimethylamino)-6-methyloxan-2-yl]-1,5-dihydroxy-9,10-dioxoanthracen-2-yl}-3-hydroxy-3-methylbutanoic acid)

3D PDB for NP0280962 (4-{6-[5-(dimethylamino)-6-methyloxan-2-yl]-1,5-dihydroxy-9,10-dioxoanthracen-2-yl}-3-hydroxy-3-methylbutanoic acid)

SMILES for NP0280962 (4-{6-[5-(dimethylamino)-6-methyloxan-2-yl]-1,5-dihydroxy-9,10-dioxoanthracen-2-yl}-3-hydroxy-3-methylbutanoic acid)

INCHI for NP0280962 (4-{6-[5-(dimethylamino)-6-methyloxan-2-yl]-1,5-dihydroxy-9,10-dioxoanthracen-2-yl}-3-hydroxy-3-methylbutanoic acid)

Structure for NP0280962 (4-{6-[5-(dimethylamino)-6-methyloxan-2-yl]-1,5-dihydroxy-9,10-dioxoanthracen-2-yl}-3-hydroxy-3-methylbutanoic acid)

3D Structure for NP0280962 (4-{6-[5-(dimethylamino)-6-methyloxan-2-yl]-1,5-dihydroxy-9,10-dioxoanthracen-2-yl}-3-hydroxy-3-methylbutanoic acid)