NP-MRD: Showing NP-Card for (2s)-2-{n-[(2s)-1-(4-decyl-3-hydroxy-2-oxo-5h-pyrrol-1-yl)-3-methyl-1-oxobutan-2-yl]-(c-hydroxycarbonimidoyl)amino}-3-phenylpropanoic acid (NP0279741)

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Record Information

Version

2.0

Created at

2022-09-09 05:14:30 UTC

Updated at

2022-09-09 05:14:31 UTC

NP-MRD ID

NP0279741

Secondary Accession Numbers

None

Natural Product Identification

Common Name

(2s)-2-{n-[(2s)-1-(4-decyl-3-hydroxy-2-oxo-5h-pyrrol-1-yl)-3-methyl-1-oxobutan-2-yl]-(c-hydroxycarbonimidoyl)amino}-3-phenylpropanoic acid

Description

Leopolic acid A, also known as leopolate a, belongs to the class of organic compounds known as phenylalanine and derivatives. Phenylalanine and derivatives are compounds containing phenylalanine or a derivative thereof resulting from reaction of phenylalanine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. (2s)-2-{n-[(2s)-1-(4-decyl-3-hydroxy-2-oxo-5h-pyrrol-1-yl)-3-methyl-1-oxobutan-2-yl]-(c-hydroxycarbonimidoyl)amino}-3-phenylpropanoic acid was first documented in 2016 (PMID: 27559415). Based on a literature review very few articles have been published on Leopolic acid A (PMID: 30344771).

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652309092207142D          

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M  END

     RDKit          3D

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M  END


  Mrv1652309092207142D          

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    2.5075   -3.9604    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8431   -3.2067    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6635   -3.1205    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.1485   -3.7879    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.8129   -4.5416    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9623   -5.9627    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2978   -5.2090    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.4472   -6.6301    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.3448   -7.0613    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6803   -6.3076    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4757   -7.1475    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8784   -7.9556    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  1  0  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  1  0  0  0  0
 10 11  1  0  0  0  0
 11 12  2  0  0  0  0
 12 13  1  0  0  0  0
 12 14  1  0  0  0  0
 14 15  2  0  0  0  0
 14 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  2  0  0  0  0
 17 19  1  0  0  0  0
 19 20  1  6  0  0  0
 20 21  1  0  0  0  0
 21 22  1  4  0  0  0
 21 23  2  0  0  0  0
 24 23  1  1  0  0  0
 24 25  1  0  0  0  0
 25 26  1  0  0  0  0
 26 27  2  0  0  0  0
 27 28  1  0  0  0  0
 28 29  2  0  0  0  0
 29 30  1  0  0  0  0
 30 31  2  0  0  0  0
 26 31  1  0  0  0  0
 24 32  1  0  0  0  0
 32 33  2  0  0  0  0
 32 34  1  0  0  0  0
 19 35  1  0  0  0  0
 35 36  1  0  0  0  0
 35 37  1  0  0  0  0
 16 38  1  0  0  0  0
 11 38  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0279741

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CCCCCCCCCCC1=C(O)C(=O)N(C1)C(=O)[C@@H](NC(O)=N[C@@H](CC1=CC=CC=C1)C(O)=O)C(C)C

> <INCHI_IDENTIFIER>
InChI=1S/C29H43N3O6/c1-4-5-6-7-8-9-10-14-17-22-19-32(27(35)25(22)33)26(34)24(20(2)3)31-29(38)30-23(28(36)37)18-21-15-12-11-13-16-21/h11-13,15-16,20,23-24,33H,4-10,14,17-19H2,1-3H3,(H,36,37)(H2,30,31,38)/t23-,24-/m0/s1

> <INCHI_KEY>
BSVQYPWIIRMJLD-ZEQRLZLVSA-N

> <FORMULA>
C29H43N3O6

> <MOLECULAR_WEIGHT>
529.678

> <EXACT_MASS>
529.315186117

> <JCHEM_ACCEPTOR_COUNT>
8

> <JCHEM_ATOM_COUNT>
81

> <JCHEM_AVERAGE_POLARIZABILITY>
59.58831026558631

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
4

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(2S)-2-{N-[(2S)-1-(4-decyl-3-hydroxy-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-3-methyl-1-oxobutan-2-yl]-(C-hydroxycarbonimidoyl)amino}-3-phenylpropanoic acid

> <JCHEM_LOGP>
5.623827356984673

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
2

> <JCHEM_PHYSIOLOGICAL_CHARGE>
-1

> <JCHEM_PKA>
5.700374365394979

> <JCHEM_PKA_STRONGEST_ACIDIC>
4.0943918730163

> <JCHEM_PKA_STRONGEST_BASIC>
3.049506007023265

> <JCHEM_POLAR_SURFACE_AREA>
139.53

> <JCHEM_REFRACTIVITY>
146.00710000000007

> <JCHEM_ROTATABLE_BOND_COUNT>
16

> <JCHEM_RULE_OF_FIVE>
0

> <JCHEM_TRADITIONAL_IUPAC>
(2S)-2-{N-[(2S)-1-(4-decyl-3-hydroxy-2-oxo-5H-pyrrol-1-yl)-3-methyl-1-oxobutan-2-yl]-(C-hydroxycarbonimidoyl)amino}-3-phenylpropanoic acid

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 09-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   09-SEP-22         0                                  
HETATM    1  C   UNK     0     -16.383 -15.477   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0     -15.050 -14.707   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0     -13.716 -15.477   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0     -12.382 -14.707   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0     -11.049 -15.477   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0      -9.715 -14.707   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0      -8.381 -15.477   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0      -7.048 -14.707   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0      -5.714 -15.477   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0      -4.380 -14.707   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0      -3.046 -15.477   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0      -2.885 -17.008   0.000  0.00  0.00           C+0
HETATM   13  O   UNK     0      -4.030 -18.039   0.000  0.00  0.00           O+0
HETATM   14  C   UNK     0      -1.379 -17.328   0.000  0.00  0.00           C+0
HETATM   15  O   UNK     0      -0.753 -18.735   0.000  0.00  0.00           O+0
HETATM   16  N   UNK     0      -0.609 -15.995   0.000  0.00  0.00           N+0
HETATM   17  C   UNK     0       0.922 -15.834   0.000  0.00  0.00           C+0
HETATM   18  O   UNK     0       1.828 -17.080   0.000  0.00  0.00           O+0
HETATM   19  C   UNK     0       1.549 -14.427   0.000  0.00  0.00           C+0
HETATM   20  N   UNK     0       3.080 -14.266   0.000  0.00  0.00           N+0
HETATM   21  C   UNK     0       3.707 -12.859   0.000  0.00  0.00           C+0
HETATM   22  O   UNK     0       2.802 -11.613   0.000  0.00  0.00           O+0
HETATM   23  N   UNK     0       5.238 -12.698   0.000  0.00  0.00           N+0
HETATM   24  C   UNK     0       5.865 -11.291   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0       4.959 -10.045   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0       5.586  -8.639   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0       4.681  -7.393   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0       5.307  -5.986   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0       6.839  -5.825   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0       7.744  -7.071   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0       7.117  -8.478   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0       7.396 -11.130   0.000  0.00  0.00           C+0
HETATM   33  O   UNK     0       8.023  -9.723   0.000  0.00  0.00           O+0
HETATM   34  O   UNK     0       8.301 -12.376   0.000  0.00  0.00           O+0
HETATM   35  C   UNK     0       0.644 -13.181   0.000  0.00  0.00           C+0
HETATM   36  C   UNK     0       1.270 -11.774   0.000  0.00  0.00           C+0
HETATM   37  C   UNK     0      -0.888 -13.342   0.000  0.00  0.00           C+0
HETATM   38  C   UNK     0      -1.640 -14.850   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4                                                       
CONECT    4    3    5                                                       
CONECT    5    4    6                                                       
CONECT    6    5    7                                                       
CONECT    7    6    8                                                       
CONECT    8    7    9                                                       
CONECT    9    8   10                                                       
CONECT   10    9   11                                                       
CONECT   11   10   12   38                                                  
CONECT   12   11   13   14                                                  
CONECT   13   12                                                            
CONECT   14   12   15   16                                                  
CONECT   15   14                                                            
CONECT   16   14   17   38                                                  
CONECT   17   16   18   19                                                  
CONECT   18   17                                                            
CONECT   19   17   20   35                                                  
CONECT   20   19   21                                                       
CONECT   21   20   22   23                                                  
CONECT   22   21                                                            
CONECT   23   21   24                                                       
CONECT   24   23   25   32                                                  
CONECT   25   24   26                                                       
CONECT   26   25   27   31                                                  
CONECT   27   26   28                                                       
CONECT   28   27   29                                                       
CONECT   29   28   30                                                       
CONECT   30   29   31                                                       
CONECT   31   30   26                                                       
CONECT   32   24   33   34                                                  
CONECT   33   32                                                            
CONECT   34   32                                                            
CONECT   35   19   36   37                                                  
CONECT   36   35                                                            
CONECT   37   35                                                            
CONECT   38   16   11                                                       
MASTER        0    0    0    0    0    0    0    0   38    0   78    0
END

View in JSmol

Synonyms

Value	Source
Leopolate a	Generator

Chemical Formula

C₂₉H₄₃N₃O₆

Average Mass

529.6780 Da

Monoisotopic Mass

529.31519 Da

IUPAC Name

(2S)-2-{N-[(2S)-1-(4-decyl-3-hydroxy-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-3-methyl-1-oxobutan-2-yl]-(C-hydroxycarbonimidoyl)amino}-3-phenylpropanoic acid

Traditional Name

(2S)-2-{N-[(2S)-1-(4-decyl-3-hydroxy-2-oxo-5H-pyrrol-1-yl)-3-methyl-1-oxobutan-2-yl]-(C-hydroxycarbonimidoyl)amino}-3-phenylpropanoic acid

CAS Registry Number

Not Available

SMILES

CCCCCCCCCCC1=C(O)C(=O)N(C1)C(=O)[C@@H](NC(O)=N[C@@H](CC1=CC=CC=C1)C(O)=O)C(C)C

InChI Identifier

InChI=1S/C29H43N3O6/c1-4-5-6-7-8-9-10-14-17-22-19-32(27(35)25(22)33)26(34)24(20(2)3)31-29(38)30-23(28(36)37)18-21-15-12-11-13-16-21/h11-13,15-16,20,23-24,33H,4-10,14,17-19H2,1-3H3,(H,36,37)(H2,30,31,38)/t23-,24-/m0/s1

InChI Key

BSVQYPWIIRMJLD-ZEQRLZLVSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Not Available

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as phenylalanine and derivatives. Phenylalanine and derivatives are compounds containing phenylalanine or a derivative thereof resulting from reaction of phenylalanine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.

Kingdom

Organic compounds

Super Class

Organic acids and derivatives

Class

Carboxylic acids and derivatives

Sub Class

Amino acids, peptides, and analogues

Direct Parent

Phenylalanine and derivatives

Alternative Parents

Substituents

Phenylalanine or derivatives
Valine or derivatives
N-carbamoyl-alpha-amino acid
N-carbamoyl-alpha-amino acid or derivatives
Alpha-amino acid amide
3-phenylpropanoic-acid
Amphetamine or derivatives
Monocyclic benzene moiety
Benzenoid
Carboxylic acid imide, n-substituted
Carboxylic acid imide
Dicarboximide
Pyrroline
Urea
Carbonic acid derivative
Carboxylic acid
Enol
Monocarboxylic acid or derivatives
Azacycle
Organoheterocyclic compound
Organic oxygen compound
Hydrocarbon derivative
Organic nitrogen compound
Organic oxide
Organopnictogen compound
Carbonyl group
Organooxygen compound
Organonitrogen compound
Aromatic heteromonocyclic compound

Molecular Framework

Aromatic heteromonocyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	5.62	ChemAxon
pKa (Strongest Acidic)	4.09	ChemAxon
pKa (Strongest Basic)	3.05	ChemAxon
Physiological Charge	-1	ChemAxon
Hydrogen Acceptor Count	8	ChemAxon
Hydrogen Donor Count	4	ChemAxon
Polar Surface Area	139.53 Å²	ChemAxon
Rotatable Bond Count	16	ChemAxon
Refractivity	146.01 m³·mol⁻¹	ChemAxon
Polarizability	59.59 Å³	ChemAxon
Number of Rings	2	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

78443392

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

71482889

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

Mattio L, Musso L, Scaglioni L, Pinto A, Martino PA, Dallavalle S: Synthesis of a leopolic acid-inspired tetramic acid with antimicrobial activity against multidrug-resistant bacteria. Beilstein J Org Chem. 2018 Sep 24;14:2482-2487. doi: 10.3762/bjoc.14.224. eCollection 2018. [PubMed:30344771 ]
Dhavan AA, Kaduskar RD, Musso L, Scaglioni L, Martino PA, Dallavalle S: Total synthesis of leopolic acid A, a natural 2,3-pyrrolidinedione with antimicrobial activity. Beilstein J Org Chem. 2016 Jul 29;12:1624-8. doi: 10.3762/bjoc.12.159. eCollection 2016. [PubMed:27559415 ]
LOTUS database [Link]

Showing NP-Card for (2s)-2-{n-[(2s)-1-(4-decyl-3-hydroxy-2-oxo-5h-pyrrol-1-yl)-3-methyl-1-oxobutan-2-yl]-(c-hydroxycarbonimidoyl)amino}-3-phenylpropanoic acid (NP0279741)

MOL for NP0279741 ((2s)-2-{n-[(2s)-1-(4-decyl-3-hydroxy-2-oxo-5h-pyrrol-1-yl)-3-methyl-1-oxobutan-2-yl]-(c-hydroxycarbonimidoyl)amino}-3-phenylpropanoic acid)

3D MOL for NP0279741 ((2s)-2-{n-[(2s)-1-(4-decyl-3-hydroxy-2-oxo-5h-pyrrol-1-yl)-3-methyl-1-oxobutan-2-yl]-(c-hydroxycarbonimidoyl)amino}-3-phenylpropanoic acid)

3D SDF for NP0279741 ((2s)-2-{n-[(2s)-1-(4-decyl-3-hydroxy-2-oxo-5h-pyrrol-1-yl)-3-methyl-1-oxobutan-2-yl]-(c-hydroxycarbonimidoyl)amino}-3-phenylpropanoic acid)

3D-SDF for NP0279741 ((2s)-2-{n-[(2s)-1-(4-decyl-3-hydroxy-2-oxo-5h-pyrrol-1-yl)-3-methyl-1-oxobutan-2-yl]-(c-hydroxycarbonimidoyl)amino}-3-phenylpropanoic acid)

PDB for NP0279741 ((2s)-2-{n-[(2s)-1-(4-decyl-3-hydroxy-2-oxo-5h-pyrrol-1-yl)-3-methyl-1-oxobutan-2-yl]-(c-hydroxycarbonimidoyl)amino}-3-phenylpropanoic acid)

3D PDB for NP0279741 ((2s)-2-{n-[(2s)-1-(4-decyl-3-hydroxy-2-oxo-5h-pyrrol-1-yl)-3-methyl-1-oxobutan-2-yl]-(c-hydroxycarbonimidoyl)amino}-3-phenylpropanoic acid)

SMILES for NP0279741 ((2s)-2-{n-[(2s)-1-(4-decyl-3-hydroxy-2-oxo-5h-pyrrol-1-yl)-3-methyl-1-oxobutan-2-yl]-(c-hydroxycarbonimidoyl)amino}-3-phenylpropanoic acid)

INCHI for NP0279741 ((2s)-2-{n-[(2s)-1-(4-decyl-3-hydroxy-2-oxo-5h-pyrrol-1-yl)-3-methyl-1-oxobutan-2-yl]-(c-hydroxycarbonimidoyl)amino}-3-phenylpropanoic acid)

Structure for NP0279741 ((2s)-2-{n-[(2s)-1-(4-decyl-3-hydroxy-2-oxo-5h-pyrrol-1-yl)-3-methyl-1-oxobutan-2-yl]-(c-hydroxycarbonimidoyl)amino}-3-phenylpropanoic acid)

3D Structure for NP0279741 ((2s)-2-{n-[(2s)-1-(4-decyl-3-hydroxy-2-oxo-5h-pyrrol-1-yl)-3-methyl-1-oxobutan-2-yl]-(c-hydroxycarbonimidoyl)amino}-3-phenylpropanoic acid)