NP-MRD: Showing NP-Card for 2,6-dichloro-1-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]-5-hydroxy-8-methylchromeno[2,3-b]pyrrol-4-one (NP0279570)

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Record Information

Version

2.0

Created at

2022-09-09 05:00:31 UTC

Updated at

2022-09-09 05:00:31 UTC

NP-MRD ID

NP0279570

Secondary Accession Numbers

None

Natural Product Identification

Common Name

2,6-dichloro-1-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]-5-hydroxy-8-methylchromeno[2,3-b]pyrrol-4-one

Description

2,6-Dichloro-1-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]-5-hydroxy-8-methyl-1H,4H-chromeno[2,3-b]pyrrol-4-one belongs to the class of organic compounds known as chromones. Chromones are compounds containing a benzopyran-4-one moiety. 2,6-dichloro-1-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]-5-hydroxy-8-methylchromeno[2,3-b]pyrrol-4-one is found in Nonomuraea spiralis. 2,6-Dichloro-1-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]-5-hydroxy-8-methyl-1H,4H-chromeno[2,3-b]pyrrol-4-one is an extremely weak basic (essentially neutral) compound (based on its pKa).

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1533004171521212D          

 30 33  0  0  0  0            999 V2000
    1.3855   -6.3545    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8334   -5.7414    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.0884   -4.9567    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5363   -4.3437    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2706   -4.5152    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7913   -3.5590    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.2392   -2.9459    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.5983   -3.3875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1503   -4.0006    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.8953   -4.7852    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4474   -5.3983    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1924   -6.1829    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.8532   -2.6029    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    1.3683   -1.9354    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5433   -1.9354    0.0000 Cl  0  0  0  0  0  0  0  0  0  0  0  0
    1.8532   -1.2680    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6378   -1.5229    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3523   -1.1104    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3523   -0.2854    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.0668   -1.5229    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7812   -1.1104    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7812   -0.2854    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.4957   -1.5229    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.2102   -1.1104    0.0000 Cl  0  0  0  0  0  0  0  0  0  0  0  0
    5.4957   -2.3479    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7812   -2.7604    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7812   -3.5854    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0668   -2.3479    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3523   -2.7604    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.6378   -2.3479    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  1  0  0  0  0
  4  5  1  0  0  0  0
  4  6  1  0  0  0  0
  6  7  1  0  0  0  0
  6  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  1  0  0  0  0
  3 10  1  0  0  0  0
 10 11  1  0  0  0  0
 11 12  1  0  0  0  0
  8 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 14 16  2  0  0  0  0
 16 17  1  0  0  0  0
 17 18  1  0  0  0  0
 18 19  2  0  0  0  0
 18 20  1  0  0  0  0
 20 21  2  0  0  0  0
 21 22  1  0  0  0  0
 21 23  1  0  0  0  0
 23 24  1  0  0  0  0
 23 25  2  0  0  0  0
 25 26  1  0  0  0  0
 26 27  1  0  0  0  0
 26 28  2  0  0  0  0
 20 28  1  0  0  0  0
 28 29  1  0  0  0  0
 29 30  1  0  0  0  0
 13 30  1  0  0  0  0
 17 30  2  0  0  0  0
M  END

     RDKit          3D

 49 52  0  0  0  0  0  0  0  0999 V2000
   -5.3234   -1.7074    0.8675 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6992   -0.7950    0.0420 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3655   -0.5693    0.3863 C   0  0  2  0  0  0  0  0  0  0  0  0
   -3.2122    0.8572    0.7593 C   0  0  2  0  0  0  0  0  0  0  0  0
   -4.1769    1.7563   -0.0125 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.4739    1.2411    0.0578 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9708    1.3984    0.6611 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9811    0.5852    0.1705 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.2223    1.3742    0.0018 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.2750    2.7129   -0.2259 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0715    3.7948   -0.3691 Cl  0  0  0  0  0  0  0  0  0  0  0  0
    1.5972    3.1146   -0.3326 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3405    1.9581   -0.1591 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.7270    1.8285   -0.1780 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4735    2.8077   -0.3653 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.2390    0.5642    0.0205 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.6101    0.3140    0.0225 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.5115    1.2923   -0.1693 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.0537   -1.0058    0.2324 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.7910   -1.2991    0.2308 Cl  0  0  0  0  0  0  0  0  0  0  0  0
    5.1366   -1.9985    0.4271 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.7808   -1.7319    0.4219 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8237   -2.8417    0.6375 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3058   -0.4525    0.2197 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0221   -0.2979    0.2314 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.4901    0.8929    0.0458 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4643   -0.0030   -1.1383 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.4192   -0.7076   -1.7784 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5170   -1.0269   -0.7573 C   0  0  2  0  0  0  0  0  0  0  0  0
   -3.2893   -1.3890   -1.8735 O   0  0  0  0  0  0  0  0  0  0  0  0
   -6.3541   -1.8291    0.5370 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.7804   -2.6949    0.8281 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.2646   -1.4049    1.9437 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1696   -1.2273    1.2821 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5363    0.9582    1.8382 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.2182    2.7448    0.5125 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8442    1.9265   -1.0496 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.9523    1.5313    0.8674 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8170   -0.2886    0.8562 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.9564    4.1059   -0.5106 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.5675    2.2271   -0.3288 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.5249   -2.9991    0.5847 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.8279   -2.6449    0.1759 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.2355   -3.7211    0.0679 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.7629   -3.1480    1.6827 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8899    0.7637   -1.8167 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7308   -0.9326   -2.6892 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9522   -1.9516   -0.4720 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8014   -2.0821   -2.3862 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  1  0
  4  5  1  0
  5  6  1  0
  4  7  1  0
  7  8  1  0
  8 27  1  0
 27 28  1  0
 27 29  1  0
 29 30  1  0
  8  9  1  0
  9 10  1  0
 10 11  1  0
 10 12  2  0
 12 13  1  0
 13 26  2  0
 26 25  1  0
 25 24  1  0
 24 22  2  0
 22 23  1  0
 22 21  1  0
 21 19  2  0
 19 20  1  0
 19 17  1  0
 17 18  1  0
 17 16  2  0
 16 14  1  0
 14 15  2  0
 29  3  1  0
 26  9  1  0
 16 24  1  0
 14 13  1  0
  1 31  1  0
  1 32  1  0
  1 33  1  0
  3 34  1  1
  4 35  1  1
  5 36  1  0
  5 37  1  0
  6 38  1  0
  8 39  1  1
 27 46  1  6
 28 47  1  0
 29 48  1  1
 30 49  1  0
 12 40  1  0
 23 43  1  0
 23 44  1  0
 23 45  1  0
 21 42  1  0
 18 41  1  0
M  END


  Mrv1533004171521212D          

 30 33  0  0  0  0            999 V2000
    1.3855   -6.3545    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8334   -5.7414    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.0884   -4.9567    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5363   -4.3437    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2706   -4.5152    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7913   -3.5590    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.2392   -2.9459    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.5983   -3.3875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1503   -4.0006    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.8953   -4.7852    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4474   -5.3983    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1924   -6.1829    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.8532   -2.6029    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    1.3683   -1.9354    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5433   -1.9354    0.0000 Cl  0  0  0  0  0  0  0  0  0  0  0  0
    1.8532   -1.2680    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6378   -1.5229    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3523   -1.1104    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3523   -0.2854    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.0668   -1.5229    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7812   -1.1104    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7812   -0.2854    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.4957   -1.5229    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.2102   -1.1104    0.0000 Cl  0  0  0  0  0  0  0  0  0  0  0  0
    5.4957   -2.3479    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7812   -2.7604    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7812   -3.5854    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0668   -2.3479    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3523   -2.7604    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.6378   -2.3479    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  1  0  0  0  0
  4  5  1  0  0  0  0
  4  6  1  0  0  0  0
  6  7  1  0  0  0  0
  6  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  1  0  0  0  0
  3 10  1  0  0  0  0
 10 11  1  0  0  0  0
 11 12  1  0  0  0  0
  8 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 14 16  2  0  0  0  0
 16 17  1  0  0  0  0
 17 18  1  0  0  0  0
 18 19  2  0  0  0  0
 18 20  1  0  0  0  0
 20 21  2  0  0  0  0
 21 22  1  0  0  0  0
 21 23  1  0  0  0  0
 23 24  1  0  0  0  0
 23 25  2  0  0  0  0
 25 26  1  0  0  0  0
 26 27  1  0  0  0  0
 26 28  2  0  0  0  0
 20 28  1  0  0  0  0
 28 29  1  0  0  0  0
 29 30  1  0  0  0  0
 13 30  1  0  0  0  0
 17 30  2  0  0  0  0
M  END
> <DATABASE_ID>
NP0279570

> <DATABASE_NAME>
NP-MRD

> <SMILES>
COC1C(CO)OC(C(O)C1O)N1C(Cl)=CC2=C1OC1=C(C)C=C(Cl)C(O)=C1C2=O

> <INCHI_IDENTIFIER>
InChI=1S/C19H19Cl2NO8/c1-6-3-8(20)13(25)11-12(24)7-4-10(21)22(18(7)30-16(6)11)19-15(27)14(26)17(28-2)9(5-23)29-19/h3-4,9,14-15,17,19,23,25-27H,5H2,1-2H3

> <INCHI_KEY>
ZXYNPGZWOMFXHV-UHFFFAOYSA-N

> <FORMULA>
C19H19Cl2NO8

> <MOLECULAR_WEIGHT>
460.26

> <EXACT_MASS>
459.048772

> <JCHEM_ACCEPTOR_COUNT>
7

> <JCHEM_ATOM_COUNT>
49

> <JCHEM_AVERAGE_POLARIZABILITY>
43.71071428139274

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
4

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
2,6-dichloro-1-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]-5-hydroxy-8-methyl-1H,4H-chromeno[2,3-b]pyrrol-4-one

> <ALOGPS_LOGP>
1.91

> <JCHEM_LOGP>
2.3646118376666663

> <ALOGPS_LOGS>
-2.70

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
4

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
12.45078010974531

> <JCHEM_PKA_STRONGEST_ACIDIC>
7.309827604750588

> <JCHEM_PKA_STRONGEST_BASIC>
-2.9807069992737087

> <JCHEM_POLAR_SURFACE_AREA>
130.61

> <JCHEM_REFRACTIVITY>
104.77119999999998

> <JCHEM_ROTATABLE_BOND_COUNT>
3

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
9.18e-01 g/l

> <JCHEM_TRADITIONAL_IUPAC>
2,6-dichloro-1-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]-5-hydroxy-8-methylchromeno[2,3-b]pyrrol-4-one

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 17-APR-15   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   17-APR-15         0                                  
HETATM    1  C   UNK     0       2.586 -11.862   0.000  0.00  0.00           C+0
HETATM    2  O   UNK     0       1.556 -10.717   0.000  0.00  0.00           O+0
HETATM    3  C   UNK     0       2.032  -9.253   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       1.001  -8.108   0.000  0.00  0.00           C+0
HETATM    5  O   UNK     0      -0.505  -8.428   0.000  0.00  0.00           O+0
HETATM    6  C   UNK     0       1.477  -6.644   0.000  0.00  0.00           C+0
HETATM    7  O   UNK     0       0.447  -5.499   0.000  0.00  0.00           O+0
HETATM    8  C   UNK     0       2.983  -6.323   0.000  0.00  0.00           C+0
HETATM    9  O   UNK     0       4.014  -7.468   0.000  0.00  0.00           O+0
HETATM   10  C   UNK     0       3.538  -8.932   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       4.568 -10.077   0.000  0.00  0.00           C+0
HETATM   12  O   UNK     0       4.093 -11.541   0.000  0.00  0.00           O+0
HETATM   13  N   UNK     0       3.459  -4.859   0.000  0.00  0.00           N+0
HETATM   14  C   UNK     0       2.554  -3.613   0.000  0.00  0.00           C+0
HETATM   15 Cl   UNK     0       1.014  -3.613   0.000  0.00  0.00          Cl+0
HETATM   16  C   UNK     0       3.459  -2.367   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       4.924  -2.843   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       6.258  -2.073   0.000  0.00  0.00           C+0
HETATM   19  O   UNK     0       6.258  -0.533   0.000  0.00  0.00           O+0
HETATM   20  C   UNK     0       7.591  -2.843   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0       8.925  -2.073   0.000  0.00  0.00           C+0
HETATM   22  O   UNK     0       8.925  -0.533   0.000  0.00  0.00           O+0
HETATM   23  C   UNK     0      10.259  -2.843   0.000  0.00  0.00           C+0
HETATM   24 Cl   UNK     0      11.592  -2.073   0.000  0.00  0.00          Cl+0
HETATM   25  C   UNK     0      10.259  -4.383   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0       8.925  -5.153   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0       8.925  -6.693   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0       7.591  -4.383   0.000  0.00  0.00           C+0
HETATM   29  O   UNK     0       6.258  -5.153   0.000  0.00  0.00           O+0
HETATM   30  C   UNK     0       4.924  -4.383   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4   10                                                  
CONECT    4    3    5    6                                                  
CONECT    5    4                                                            
CONECT    6    4    7    8                                                  
CONECT    7    6                                                            
CONECT    8    6    9   13                                                  
CONECT    9    8   10                                                       
CONECT   10    9    3   11                                                  
CONECT   11   10   12                                                       
CONECT   12   11                                                            
CONECT   13    8   14   30                                                  
CONECT   14   13   15   16                                                  
CONECT   15   14                                                            
CONECT   16   14   17                                                       
CONECT   17   16   18   30                                                  
CONECT   18   17   19   20                                                  
CONECT   19   18                                                            
CONECT   20   18   21   28                                                  
CONECT   21   20   22   23                                                  
CONECT   22   21                                                            
CONECT   23   21   24   25                                                  
CONECT   24   23                                                            
CONECT   25   23   26                                                       
CONECT   26   25   27   28                                                  
CONECT   27   26                                                            
CONECT   28   26   20   29                                                  
CONECT   29   28   30                                                       
CONECT   30   29   13   17                                                  
MASTER        0    0    0    0    0    0    0    0   30    0   66    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₁₉H₁₉Cl₂NO₈

Average Mass

460.2600 Da

Monoisotopic Mass

459.04877 Da

IUPAC Name

2,6-dichloro-1-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]-5-hydroxy-8-methyl-1H,4H-chromeno[2,3-b]pyrrol-4-one

Traditional Name

2,6-dichloro-1-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]-5-hydroxy-8-methylchromeno[2,3-b]pyrrol-4-one

CAS Registry Number

Not Available

SMILES

COC1C(CO)OC(C(O)C1O)N1C(Cl)=CC2=C1OC1=C(C)C=C(Cl)C(O)=C1C2=O

InChI Identifier

InChI=1S/C19H19Cl2NO8/c1-6-3-8(20)13(25)11-12(24)7-4-10(21)22(18(7)30-16(6)11)19-15(27)14(26)17(28-2)9(5-23)29-19/h3-4,9,14-15,17,19,23,25-27H,5H2,1-2H3

InChI Key

ZXYNPGZWOMFXHV-UHFFFAOYSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Nonomuraea spiralis	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as chromones. Chromones are compounds containing a benzopyran-4-one moiety.

Kingdom

Organic compounds

Super Class

Organoheterocyclic compounds

Class

Benzopyrans

Sub Class

1-benzopyrans

Direct Parent

Chromones

Alternative Parents

Substituents

Chromone
Glycosyl compound
N-glycosyl compound
2-halophenol
Phenol
Pyranone
Benzenoid
Substituted pyrrole
Pyran
Aryl chloride
Aryl halide
Oxane
Monosaccharide
Heteroaromatic compound
Vinylogous amide
Vinylogous acid
Pyrrole
Secondary alcohol
1,2-diol
Azacycle
Oxacycle
Dialkyl ether
Ether
Hydrocarbon derivative
Organic oxide
Organic oxygen compound
Alcohol
Organic nitrogen compound
Primary alcohol
Organooxygen compound
Organohalogen compound
Organochloride
Organonitrogen compound
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	1.91	ALOGPS
logP	2.36	ChemAxon
logS	-2.7	ALOGPS
pKa (Strongest Acidic)	7.31	ChemAxon
pKa (Strongest Basic)	-3	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	7	ChemAxon
Hydrogen Donor Count	4	ChemAxon
Polar Surface Area	130.61 Å²	ChemAxon
Rotatable Bond Count	3	ChemAxon
Refractivity	104.77 m³·mol⁻¹	ChemAxon
Polarizability	43.71 Å³	ChemAxon
Number of Rings	4	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

10072932

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for 2,6-dichloro-1-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]-5-hydroxy-8-methylchromeno[2,3-b]pyrrol-4-one (NP0279570)

MOL for NP0279570 (2,6-dichloro-1-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]-5-hydroxy-8-methylchromeno[2,3-b]pyrrol-4-one)

3D MOL for NP0279570 (2,6-dichloro-1-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]-5-hydroxy-8-methylchromeno[2,3-b]pyrrol-4-one)

3D SDF for NP0279570 (2,6-dichloro-1-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]-5-hydroxy-8-methylchromeno[2,3-b]pyrrol-4-one)

3D-SDF for NP0279570 (2,6-dichloro-1-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]-5-hydroxy-8-methylchromeno[2,3-b]pyrrol-4-one)

PDB for NP0279570 (2,6-dichloro-1-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]-5-hydroxy-8-methylchromeno[2,3-b]pyrrol-4-one)

3D PDB for NP0279570 (2,6-dichloro-1-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]-5-hydroxy-8-methylchromeno[2,3-b]pyrrol-4-one)

SMILES for NP0279570 (2,6-dichloro-1-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]-5-hydroxy-8-methylchromeno[2,3-b]pyrrol-4-one)

INCHI for NP0279570 (2,6-dichloro-1-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]-5-hydroxy-8-methylchromeno[2,3-b]pyrrol-4-one)

Structure for NP0279570 (2,6-dichloro-1-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]-5-hydroxy-8-methylchromeno[2,3-b]pyrrol-4-one)

3D Structure for NP0279570 (2,6-dichloro-1-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]-5-hydroxy-8-methylchromeno[2,3-b]pyrrol-4-one)