NP-MRD: Showing NP-Card for (3as,6s,6ar,9ar,9br)-8-chloro-6,9a-dimethyl-3-methylidene-3ah,4h,5h,6h,6ah,9bh-azuleno[4,5-b]furan-2,9-dione (NP0277085)

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Record Information

Version

1.0

Created at

2022-09-09 01:32:48 UTC

Updated at

2022-09-09 01:32:48 UTC

NP-MRD ID

NP0277085

Secondary Accession Numbers

None

Natural Product Identification

Common Name

(3as,6s,6ar,9ar,9br)-8-chloro-6,9a-dimethyl-3-methylidene-3ah,4h,5h,6h,6ah,9bh-azuleno[4,5-b]furan-2,9-dione

Description

Chloroambrosin belongs to the class of organic compounds known as ambrosanolides and secoambrosanolides. These are sesquiterpene lactones from the Ambrosia family, with a backbone derivative of azuleno[6,5-b]furan-2-one (ambrosanolides) or azuleno[4,5-b]furan-2-one (secoambrosanolides). (3as,6s,6ar,9ar,9br)-8-chloro-6,9a-dimethyl-3-methylidene-3ah,4h,5h,6h,6ah,9bh-azuleno[4,5-b]furan-2,9-dione is found in Ambrosia maritima. Based on a literature review very few articles have been published on Chloroambrosin.

Structure

MOL 3D MOL SDF PDB SMILES InChI

     RDKit          3D

 36 38  0  0  0  0  0  0  0  0999 V2000
    2.7375    0.5102   -2.3086 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4768    0.5282   -1.0103 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8547    1.5713   -0.0622 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.8306    2.3884   -0.1886 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.9700    1.5057    0.9788 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.1838    0.3121    0.9048 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.7501   -0.4822   -0.1975 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.8559   -1.3574   -0.9772 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0522   -2.1321   -0.1016 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3704   -1.5045    0.2026 C   0  0  2  0  0  0  0  0  0  0  0  0
   -2.2149   -1.2950   -1.0071 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2204   -0.3738    1.1213 C   0  0  2  0  0  0  0  0  0  0  0  0
   -2.4331    0.3737    1.4526 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0364    1.5292    1.9755 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0715    2.8458    2.5671 Cl  0  0  0  0  0  0  0  0  0  0  0  0
   -0.5705    1.5742    1.9824 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1827    2.1814    2.7533 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2476    0.6910    0.8107 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.5760    1.5398   -0.3868 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3893   -0.3382   -2.8832 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.2812    1.3223   -2.7680 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.3402   -0.1965    1.8852 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.5621   -1.1377    0.2404 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.5175   -2.1111   -1.5069 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.3026   -0.8729   -1.8037 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2770   -3.1238   -0.5960 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.4583   -2.4107    0.8478 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9320   -2.3093    0.7781 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4598   -2.3232   -1.4115 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7298   -0.7714   -1.8399 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2036   -0.8658   -0.7380 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8749   -0.8149    2.1121 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4739    0.0825    1.3164 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.1953    1.4417   -1.2058 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5989    1.3742   -0.7794 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5458    2.6488   -0.1568 H   0  0  0  0  0  0  0  0  0  0  0  0
 11 10  1  0
 10  9  1  0
  9  8  1  0
  8  7  1  0
  7  6  1  0
  6  5  1  0
  5  3  1  0
  3  4  2  0
  3  2  1  0
  2  1  2  3
  6 18  1  0
 18 19  1  6
 18 12  1  0
 12 13  1  0
 13 14  2  0
 14 15  1  0
 14 16  1  0
 16 17  2  0
 12 10  1  0
  2  7  1  0
 16 18  1  0
 11 29  1  0
 11 30  1  0
 11 31  1  0
 10 28  1  1
  9 26  1  0
  9 27  1  0
  8 24  1  0
  8 25  1  0
  7 23  1  1
  6 22  1  1
  1 20  1  0
  1 21  1  0
 19 34  1  0
 19 35  1  0
 19 36  1  0
 12 32  1  1
 13 33  1  0
M  END


  Mrv1652309092203322D          

 19 21  0  0  1  0            999 V2000
    5.6412   -1.0466    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.9527   -0.5921    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.9157    0.2321    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.5607    0.7464    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.1204    0.4515    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.6659   -0.2370    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.1803   -0.8820    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.9967   -1.6863    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2534   -2.0443    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5101   -1.6863    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.8651   -2.2007    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3265   -0.8820    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.5541   -0.5921    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5912    0.2321    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9461    0.7464    0.0000 Cl  0  0  0  0  0  0  0  0  0  0  0  0
    2.3864    0.4515    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6763    1.2239    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.8409   -0.2370    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.2319    0.4895    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  3  5  1  0  0  0  0
  6  5  1  6  0  0  0
  6  7  1  0  0  0  0
  7  2  1  6  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  1  0  0  0  0
 10 11  1  6  0  0  0
 10 12  1  0  0  0  0
 12 13  1  6  0  0  0
 13 14  2  0  0  0  0
 14 15  1  0  0  0  0
 14 16  1  0  0  0  0
 16 17  2  0  0  0  0
 16 18  1  0  0  0  0
 12 18  1  0  0  0  0
  6 18  1  0  0  0  0
 18 19  1  6  0  0  0
M  END
> <DATABASE_ID>
NP0277085

> <DATABASE_NAME>
NP-MRD

> <SMILES>
C[C@H]1CC[C@@H]2[C@@H](OC(=O)C2=C)[C@@]2(C)[C@H]1C=C(Cl)C2=O

> <INCHI_IDENTIFIER>
InChI=1S/C15H17ClO3/c1-7-4-5-9-8(2)14(18)19-13(9)15(3)10(7)6-11(16)12(15)17/h6-7,9-10,13H,2,4-5H2,1,3H3/t7-,9-,10-,13+,15-/m0/s1

> <INCHI_KEY>
IWODEDMZZHXMJY-UHEPVNHGSA-N

> <FORMULA>
C15H17ClO3

> <MOLECULAR_WEIGHT>
280.75

> <EXACT_MASS>
280.0866221

> <JCHEM_ACCEPTOR_COUNT>
2

> <JCHEM_ATOM_COUNT>
36

> <JCHEM_AVERAGE_POLARIZABILITY>
28.556850226297513

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
0

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
(3aS,6S,6aR,9aR,9bR)-8-chloro-6,9a-dimethyl-3-methylidene-2H,3H,3aH,4H,5H,6H,6aH,9H,9aH,9bH-azuleno[4,5-b]furan-2,9-dione

> <JCHEM_LOGP>
3.581021037999999

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
3

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA_STRONGEST_BASIC>
-6.425666988484968

> <JCHEM_POLAR_SURFACE_AREA>
43.370000000000005

> <JCHEM_REFRACTIVITY>
72.8437

> <JCHEM_ROTATABLE_BOND_COUNT>
0

> <JCHEM_RULE_OF_FIVE>
1

> <JCHEM_TRADITIONAL_IUPAC>
(3aS,6S,6aR,9aR,9bR)-8-chloro-6,9a-dimethyl-3-methylidene-3aH,4H,5H,6H,6aH,9bH-azuleno[4,5-b]furan-2,9-dione

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 09-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   09-SEP-22         0                                  
HETATM    1  C   UNK     0      10.530  -1.954   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       9.245  -1.105   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       9.176   0.433   0.000  0.00  0.00           C+0
HETATM    4  O   UNK     0      10.380   1.393   0.000  0.00  0.00           O+0
HETATM    5  O   UNK     0       7.691   0.843   0.000  0.00  0.00           O+0
HETATM    6  C   UNK     0       6.843  -0.442   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       7.803  -1.646   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       7.461  -3.148   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       6.073  -3.816   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       4.686  -3.148   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       3.482  -4.108   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       4.343  -1.646   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       2.901  -1.105   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       2.970   0.433   0.000  0.00  0.00           C+0
HETATM   15 Cl   UNK     0       1.766   1.393   0.000  0.00  0.00          Cl+0
HETATM   16  C   UNK     0       4.455   0.843   0.000  0.00  0.00           C+0
HETATM   17  O   UNK     0       4.996   2.285   0.000  0.00  0.00           O+0
HETATM   18  C   UNK     0       5.303  -0.442   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       6.033   0.914   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3    7                                                  
CONECT    3    2    4    5                                                  
CONECT    4    3                                                            
CONECT    5    3    6                                                       
CONECT    6    5    7   18                                                  
CONECT    7    6    2    8                                                  
CONECT    8    7    9                                                       
CONECT    9    8   10                                                       
CONECT   10    9   11   12                                                  
CONECT   11   10                                                            
CONECT   12   10   13   18                                                  
CONECT   13   12   14                                                       
CONECT   14   13   15   16                                                  
CONECT   15   14                                                            
CONECT   16   14   17   18                                                  
CONECT   17   16                                                            
CONECT   18   16   12    6   19                                             
CONECT   19   18                                                            
MASTER        0    0    0    0    0    0    0    0   19    0   42    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₁₅H₁₇ClO₃

Average Mass

280.7500 Da

Monoisotopic Mass

280.08662 Da

IUPAC Name

(3aS,6S,6aR,9aR,9bR)-8-chloro-6,9a-dimethyl-3-methylidene-2H,3H,3aH,4H,5H,6H,6aH,9H,9aH,9bH-azuleno[4,5-b]furan-2,9-dione

Traditional Name

(3aS,6S,6aR,9aR,9bR)-8-chloro-6,9a-dimethyl-3-methylidene-3aH,4H,5H,6H,6aH,9bH-azuleno[4,5-b]furan-2,9-dione

CAS Registry Number

Not Available

SMILES

C[C@H]1CC[C@@H]2[C@@H](OC(=O)C2=C)[C@@]2(C)[C@H]1C=C(Cl)C2=O

InChI Identifier

InChI=1S/C15H17ClO3/c1-7-4-5-9-8(2)14(18)19-13(9)15(3)10(7)6-11(16)12(15)17/h6-7,9-10,13H,2,4-5H2,1,3H3/t7-,9-,10-,13+,15-/m0/s1

InChI Key

IWODEDMZZHXMJY-UHEPVNHGSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Ambrosia maritima	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as ambrosanolides and secoambrosanolides. These are sesquiterpene lactones from the Ambrosia family, with a backbone derivative of azuleno[6,5-b]furan-2-one (ambrosanolides) or azuleno[4,5-b]furan-2-one (secoambrosanolides).

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Prenol lipids

Sub Class

Terpene lactones

Direct Parent

Ambrosanolides and secoambrosanolides

Alternative Parents

Substituents

Ambrosanolide
Pseudoguaiane sesquiterpenoid
Sesquiterpenoid
Gamma butyrolactone
Alpha-haloketone
Alpha-chloroketone
Tetrahydrofuran
Enoate ester
Alpha,beta-unsaturated carboxylic ester
Carboxylic acid ester
Ketone
Lactone
Vinyl chloride
Chloroalkene
Oxacycle
Monocarboxylic acid or derivatives
Carboxylic acid derivative
Vinyl halide
Haloalkene
Organoheterocyclic compound
Hydrocarbon derivative
Organooxygen compound
Organochloride
Organohalogen compound
Carbonyl group
Organic oxygen compound
Organic oxide
Aliphatic heteropolycyclic compound

Molecular Framework

Aliphatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	3.58	ChemAxon
pKa (Strongest Basic)	-6.4	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	2	ChemAxon
Hydrogen Donor Count	0	ChemAxon
Polar Surface Area	43.37 Å²	ChemAxon
Rotatable Bond Count	0	ChemAxon
Refractivity	72.84 m³·mol⁻¹	ChemAxon
Polarizability	28.56 Å³	ChemAxon
Number of Rings	3	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

158920

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

182744

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for (3as,6s,6ar,9ar,9br)-8-chloro-6,9a-dimethyl-3-methylidene-3ah,4h,5h,6h,6ah,9bh-azuleno[4,5-b]furan-2,9-dione (NP0277085)

MOL for NP0277085 ((3as,6s,6ar,9ar,9br)-8-chloro-6,9a-dimethyl-3-methylidene-3ah,4h,5h,6h,6ah,9bh-azuleno[4,5-b]furan-2,9-dione)

3D MOL for NP0277085 ((3as,6s,6ar,9ar,9br)-8-chloro-6,9a-dimethyl-3-methylidene-3ah,4h,5h,6h,6ah,9bh-azuleno[4,5-b]furan-2,9-dione)

3D SDF for NP0277085 ((3as,6s,6ar,9ar,9br)-8-chloro-6,9a-dimethyl-3-methylidene-3ah,4h,5h,6h,6ah,9bh-azuleno[4,5-b]furan-2,9-dione)

3D-SDF for NP0277085 ((3as,6s,6ar,9ar,9br)-8-chloro-6,9a-dimethyl-3-methylidene-3ah,4h,5h,6h,6ah,9bh-azuleno[4,5-b]furan-2,9-dione)

PDB for NP0277085 ((3as,6s,6ar,9ar,9br)-8-chloro-6,9a-dimethyl-3-methylidene-3ah,4h,5h,6h,6ah,9bh-azuleno[4,5-b]furan-2,9-dione)

3D PDB for NP0277085 ((3as,6s,6ar,9ar,9br)-8-chloro-6,9a-dimethyl-3-methylidene-3ah,4h,5h,6h,6ah,9bh-azuleno[4,5-b]furan-2,9-dione)

SMILES for NP0277085 ((3as,6s,6ar,9ar,9br)-8-chloro-6,9a-dimethyl-3-methylidene-3ah,4h,5h,6h,6ah,9bh-azuleno[4,5-b]furan-2,9-dione)

INCHI for NP0277085 ((3as,6s,6ar,9ar,9br)-8-chloro-6,9a-dimethyl-3-methylidene-3ah,4h,5h,6h,6ah,9bh-azuleno[4,5-b]furan-2,9-dione)

Structure for NP0277085 ((3as,6s,6ar,9ar,9br)-8-chloro-6,9a-dimethyl-3-methylidene-3ah,4h,5h,6h,6ah,9bh-azuleno[4,5-b]furan-2,9-dione)

3D Structure for NP0277085 ((3as,6s,6ar,9ar,9br)-8-chloro-6,9a-dimethyl-3-methylidene-3ah,4h,5h,6h,6ah,9bh-azuleno[4,5-b]furan-2,9-dione)