NP-MRD: Showing NP-Card for methyl (3's,5as,7ar,8r,9r,11ar,11br)-9-(furan-3-carbonyl)-5,5,7a,9,11b-pentamethyl-3,7-dioxo-6,10,11,11a-tetrahydro-5ah-spiro[naphtho[2,1-c]oxepine-8,2'-oxirane]-3'-carboxylate (NP0276667)

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Record Information

Version

2.0

Created at

2022-09-09 00:54:36 UTC

Updated at

2022-09-09 00:54:36 UTC

NP-MRD ID

NP0276667

Secondary Accession Numbers

None

Natural Product Identification

Common Name

methyl (3's,5as,7ar,8r,9r,11ar,11br)-9-(furan-3-carbonyl)-5,5,7a,9,11b-pentamethyl-3,7-dioxo-6,10,11,11a-tetrahydro-5ah-spiro[naphtho[2,1-c]oxepine-8,2'-oxirane]-3'-carboxylate

Description

Methyl (3'S,5aS,7aR,8R,9R,11aR,11bR)-9-(furan-3-carbonyl)-5,5,7a,9,11b-pentamethyl-3,7-dioxo-5,5a,6,7,7a,9,10,11,11a,11b-decahydro-3H-spiro[naphtho[2,1-c]oxepine-8,2'-oxirane]-3'-carboxylate belongs to the class of organic compounds known as limonoids. These are highly oxygenated, modified terpenoids with a prototypical structure either containing or derived from a precursor with a 4,4,8-trimethyl-17-furanylsteroid skeleton. All naturally occurring citrus limonoids contain a furan ring attached to the D-ring, at C-17, as well as oxygen containing functional groups at C-3, C-4, C-7, C-16 and C-17. Based on a literature review very few articles have been published on methyl (3'S,5aS,7aR,8R,9R,11aR,11bR)-9-(furan-3-carbonyl)-5,5,7a,9,11b-pentamethyl-3,7-dioxo-5,5a,6,7,7a,9,10,11,11a,11b-decahydro-3H-spiro[naphtho[2,1-c]oxepine-8,2'-oxirane]-3'-carboxylate.

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652309092202542D          

 35 39  0  0  1  0            999 V2000
   -0.1439   -4.5697    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6301   -4.8551    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.2643   -4.3275    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0384   -4.6129    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.1245   -3.5144    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.5969   -2.8802    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.4100   -2.7404    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.2701   -1.9273    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.4937   -2.2062    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8607   -1.2111    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2762   -0.4984    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
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  7 34  1  0  0  0  0
 34 35  1  6  0  0  0
M  END

     RDKit          3D

 67 71  0  0  0  0  0  0  0  0999 V2000
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M  END


  Mrv1652309092202542D          

 35 39  0  0  1  0            999 V2000
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 19 20  1  0  0  0  0
 20 21  1  6  0  0  0
 20 22  1  0  0  0  0
 22 23  2  0  0  0  0
 23 24  1  0  0  0  0
 24 25  2  0  0  0  0
 24 26  1  0  0  0  0
 26 27  1  0  0  0  0
 27 28  1  0  0  0  0
 27 29  1  0  0  0  0
 27 30  1  0  0  0  0
 20 30  1  0  0  0  0
 30 31  1  1  0  0  0
 31 32  1  0  0  0  0
 32 33  2  0  0  0  0
 32 34  1  0  0  0  0
 19 34  1  0  0  0  0
  7 34  1  0  0  0  0
 34 35  1  6  0  0  0
M  END
> <DATABASE_ID>
NP0276667

> <DATABASE_NAME>
NP-MRD

> <SMILES>
COC(=O)[C@H]1O[C@@]11[C@@](C)(CC[C@@H]2[C@@]3(C)C=CC(=O)OC(C)(C)[C@H]3CC(=O)[C@@]12C)C(=O)C1=COC=C1

> <INCHI_IDENTIFIER>
InChI=1S/C27H32O8/c1-23(2)17-13-18(28)26(5)16(24(17,3)10-8-19(29)34-23)7-11-25(4,20(30)15-9-12-33-14-15)27(26)21(35-27)22(31)32-6/h8-10,12,14,16-17,21H,7,11,13H2,1-6H3/t16-,17-,21-,24-,25+,26+,27-/m1/s1

> <INCHI_KEY>
UCOPOTMGOFAKFC-OXTGLVGQSA-N

> <FORMULA>
C27H32O8

> <MOLECULAR_WEIGHT>
484.545

> <EXACT_MASS>
484.20971799

> <JCHEM_ACCEPTOR_COUNT>
5

> <JCHEM_ATOM_COUNT>
67

> <JCHEM_AVERAGE_POLARIZABILITY>
49.654009167312985

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
0

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
methyl (3'S,5aS,7aR,8R,9R,11aR,11bR)-9-(furan-3-carbonyl)-5,5,7a,9,11b-pentamethyl-3,7-dioxo-5,5a,6,7,7a,9,10,11,11a,11b-decahydro-3H-spiro[naphtho[2,1-c]oxepine-8,2'-oxirane]-3'-carboxylate

> <JCHEM_LOGP>
3.806204703999999

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
5

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA_STRONGEST_ACIDIC>
17.91946038105326

> <JCHEM_PKA_STRONGEST_BASIC>
-3.0056192366565346

> <JCHEM_POLAR_SURFACE_AREA>
112.41

> <JCHEM_REFRACTIVITY>
123.92449999999998

> <JCHEM_ROTATABLE_BOND_COUNT>
4

> <JCHEM_RULE_OF_FIVE>
1

> <JCHEM_TRADITIONAL_IUPAC>
methyl (3'S,5aS,7aR,8R,9R,11aR,11bR)-9-(furan-3-carbonyl)-5,5,7a,9,11b-pentamethyl-3,7-dioxo-6,10,11,11a-tetrahydro-5aH-spiro[naphtho[2,1-c]oxepine-8,2'-oxirane]-3'-carboxylate

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 09-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   09-SEP-22         0                                  
HETATM    1  C   UNK     0      -0.269  -8.530   0.000  0.00  0.00           C+0
HETATM    2  O   UNK     0       1.176  -9.063   0.000  0.00  0.00           O+0
HETATM    3  C   UNK     0       2.360  -8.078   0.000  0.00  0.00           C+0
HETATM    4  O   UNK     0       3.805  -8.611   0.000  0.00  0.00           O+0
HETATM    5  C   UNK     0       2.099  -6.560   0.000  0.00  0.00           C+0
HETATM    6  O   UNK     0       1.114  -5.376   0.000  0.00  0.00           O+0
HETATM    7  C   UNK     0       2.632  -5.115   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       2.371  -3.598   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       0.922  -4.118   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       1.607  -2.261   0.000  0.00  0.00           C+0
HETATM   11  O   UNK     0       2.382  -0.930   0.000  0.00  0.00           O+0
HETATM   12  C   UNK     0       0.067  -2.254   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0      -0.844  -3.496   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0      -2.306  -3.014   0.000  0.00  0.00           C+0
HETATM   15  O   UNK     0      -2.300  -1.474   0.000  0.00  0.00           O+0
HETATM   16  C   UNK     0      -0.833  -1.005   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       3.555  -2.613   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       5.000  -3.146   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       5.261  -4.663   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0       6.706  -5.196   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0       6.332  -3.702   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0       7.729  -4.046   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0       9.267  -4.129   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0      10.161  -5.383   0.000  0.00  0.00           C+0
HETATM   25  O   UNK     0      11.679  -5.122   0.000  0.00  0.00           O+0
HETATM   26  O   UNK     0       9.737  -6.864   0.000  0.00  0.00           O+0
HETATM   27  C   UNK     0       8.316  -7.456   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0       9.210  -8.710   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0       7.292  -8.606   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0       6.967  -6.714   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0       5.783  -7.699   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0       4.338  -7.166   0.000  0.00  0.00           C+0
HETATM   33  O   UNK     0       4.439  -8.703   0.000  0.00  0.00           O+0
HETATM   34  C   UNK     0       4.077  -5.648   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0       2.893  -6.633   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4    5                                                  
CONECT    4    3                                                            
CONECT    5    3    6    7                                                  
CONECT    6    5    7                                                       
CONECT    7    6    5    8   34                                             
CONECT    8    7    9   10   17                                             
CONECT    9    8                                                            
CONECT   10    8   11   12                                                  
CONECT   11   10                                                            
CONECT   12   10   13   16                                                  
CONECT   13   12   14                                                       
CONECT   14   13   15                                                       
CONECT   15   14   16                                                       
CONECT   16   15   12                                                       
CONECT   17    8   18                                                       
CONECT   18   17   19                                                       
CONECT   19   18   20   34                                                  
CONECT   20   19   21   22   30                                             
CONECT   21   20                                                            
CONECT   22   20   23                                                       
CONECT   23   22   24                                                       
CONECT   24   23   25   26                                                  
CONECT   25   24                                                            
CONECT   26   24   27                                                       
CONECT   27   26   28   29   30                                             
CONECT   28   27                                                            
CONECT   29   27                                                            
CONECT   30   27   20   31                                                  
CONECT   31   30   32                                                       
CONECT   32   31   33   34                                                  
CONECT   33   32                                                            
CONECT   34   32   19    7   35                                             
CONECT   35   34                                                            
MASTER        0    0    0    0    0    0    0    0   35    0   78    0
END

View in JSmol

Synonyms

Value	Source
Methyl (3's,5as,7ar,8R,9R,11ar,11BR)-9-(furan-3-carbonyl)-5,5,7a,9,11b-pentamethyl-3,7-dioxo-5,5a,6,7,7a,9,10,11,11a,11b-decahydro-3H-spiro[naphtho[2,1-c]oxepine-8,2'-oxirane]-3'-carboxylic acid	Generator

Chemical Formula

C₂₇H₃₂O₈

Average Mass

484.5450 Da

Monoisotopic Mass

484.20972 Da

IUPAC Name

methyl (3'S,5aS,7aR,8R,9R,11aR,11bR)-9-(furan-3-carbonyl)-5,5,7a,9,11b-pentamethyl-3,7-dioxo-5,5a,6,7,7a,9,10,11,11a,11b-decahydro-3H-spiro[naphtho[2,1-c]oxepine-8,2'-oxirane]-3'-carboxylate

Traditional Name

methyl (3'S,5aS,7aR,8R,9R,11aR,11bR)-9-(furan-3-carbonyl)-5,5,7a,9,11b-pentamethyl-3,7-dioxo-6,10,11,11a-tetrahydro-5aH-spiro[naphtho[2,1-c]oxepine-8,2'-oxirane]-3'-carboxylate

CAS Registry Number

Not Available

SMILES

COC(=O)[C@H]1O[C@@]11[C@@](C)(CC[C@@H]2[C@@]3(C)C=CC(=O)OC(C)(C)[C@H]3CC(=O)[C@@]12C)C(=O)C1=COC=C1

InChI Identifier

InChI=1S/C27H32O8/c1-23(2)17-13-18(28)26(5)16(24(17,3)10-8-19(29)34-23)7-11-25(4,20(30)15-9-12-33-14-15)27(26)21(35-27)22(31)32-6/h8-10,12,14,16-17,21H,7,11,13H2,1-6H3/t16-,17-,21-,24-,25+,26+,27-/m1/s1

InChI Key

UCOPOTMGOFAKFC-OXTGLVGQSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Not Available

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as limonoids. These are highly oxygenated, modified terpenoids with a prototypical structure either containing or derived from a precursor with a 4,4,8-trimethyl-17-furanylsteroid skeleton. All naturally occurring citrus limonoids contain a furan ring attached to the D-ring, at C-17, as well as oxygen containing functional groups at C-3, C-4, C-7, C-16 and C-17.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Prenol lipids

Sub Class

Triterpenoids

Direct Parent

Limonoids

Alternative Parents

Substituents

Limonoid skeleton
Aryl ketone
Aryl alkyl ketone
Dicarboxylic acid or derivatives
Oxirane carboxylic acid
Oxirane carboxylic acid or derivatives
Heteroaromatic compound
Furan
Alpha,beta-unsaturated carboxylic ester
Enoate ester
Methyl ester
Carboxylic acid ester
Ketone
Lactone
Organoheterocyclic compound
Oxacycle
Ether
Oxirane
Dialkyl ether
Carboxylic acid derivative
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Carbonyl group
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	3.81	ChemAxon
pKa (Strongest Acidic)	17.92	ChemAxon
pKa (Strongest Basic)	-3	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	5	ChemAxon
Hydrogen Donor Count	0	ChemAxon
Polar Surface Area	112.41 Å²	ChemAxon
Rotatable Bond Count	4	ChemAxon
Refractivity	123.92 m³·mol⁻¹	ChemAxon
Polarizability	49.65 Å³	ChemAxon
Number of Rings	5	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

162984920

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for methyl (3's,5as,7ar,8r,9r,11ar,11br)-9-(furan-3-carbonyl)-5,5,7a,9,11b-pentamethyl-3,7-dioxo-6,10,11,11a-tetrahydro-5ah-spiro[naphtho[2,1-c]oxepine-8,2'-oxirane]-3'-carboxylate (NP0276667)

MOL for NP0276667 (methyl (3's,5as,7ar,8r,9r,11ar,11br)-9-(furan-3-carbonyl)-5,5,7a,9,11b-pentamethyl-3,7-dioxo-6,10,11,11a-tetrahydro-5ah-spiro[naphtho[2,1-c]oxepine-8,2'-oxirane]-3'-carboxylate)

3D MOL for NP0276667 (methyl (3's,5as,7ar,8r,9r,11ar,11br)-9-(furan-3-carbonyl)-5,5,7a,9,11b-pentamethyl-3,7-dioxo-6,10,11,11a-tetrahydro-5ah-spiro[naphtho[2,1-c]oxepine-8,2'-oxirane]-3'-carboxylate)

3D SDF for NP0276667 (methyl (3's,5as,7ar,8r,9r,11ar,11br)-9-(furan-3-carbonyl)-5,5,7a,9,11b-pentamethyl-3,7-dioxo-6,10,11,11a-tetrahydro-5ah-spiro[naphtho[2,1-c]oxepine-8,2'-oxirane]-3'-carboxylate)

3D-SDF for NP0276667 (methyl (3's,5as,7ar,8r,9r,11ar,11br)-9-(furan-3-carbonyl)-5,5,7a,9,11b-pentamethyl-3,7-dioxo-6,10,11,11a-tetrahydro-5ah-spiro[naphtho[2,1-c]oxepine-8,2'-oxirane]-3'-carboxylate)

PDB for NP0276667 (methyl (3's,5as,7ar,8r,9r,11ar,11br)-9-(furan-3-carbonyl)-5,5,7a,9,11b-pentamethyl-3,7-dioxo-6,10,11,11a-tetrahydro-5ah-spiro[naphtho[2,1-c]oxepine-8,2'-oxirane]-3'-carboxylate)

3D PDB for NP0276667 (methyl (3's,5as,7ar,8r,9r,11ar,11br)-9-(furan-3-carbonyl)-5,5,7a,9,11b-pentamethyl-3,7-dioxo-6,10,11,11a-tetrahydro-5ah-spiro[naphtho[2,1-c]oxepine-8,2'-oxirane]-3'-carboxylate)

SMILES for NP0276667 (methyl (3's,5as,7ar,8r,9r,11ar,11br)-9-(furan-3-carbonyl)-5,5,7a,9,11b-pentamethyl-3,7-dioxo-6,10,11,11a-tetrahydro-5ah-spiro[naphtho[2,1-c]oxepine-8,2'-oxirane]-3'-carboxylate)

INCHI for NP0276667 (methyl (3's,5as,7ar,8r,9r,11ar,11br)-9-(furan-3-carbonyl)-5,5,7a,9,11b-pentamethyl-3,7-dioxo-6,10,11,11a-tetrahydro-5ah-spiro[naphtho[2,1-c]oxepine-8,2'-oxirane]-3'-carboxylate)

Structure for NP0276667 (methyl (3's,5as,7ar,8r,9r,11ar,11br)-9-(furan-3-carbonyl)-5,5,7a,9,11b-pentamethyl-3,7-dioxo-6,10,11,11a-tetrahydro-5ah-spiro[naphtho[2,1-c]oxepine-8,2'-oxirane]-3'-carboxylate)

3D Structure for NP0276667 (methyl (3's,5as,7ar,8r,9r,11ar,11br)-9-(furan-3-carbonyl)-5,5,7a,9,11b-pentamethyl-3,7-dioxo-6,10,11,11a-tetrahydro-5ah-spiro[naphtho[2,1-c]oxepine-8,2'-oxirane]-3'-carboxylate)