NP-MRD: Showing NP-Card for 2-[(1-{1-[(4,5-dihydroxy-6-methyloxan-2-yl)oxy]ethyl}-1-hydroxy-9a,11a-dimethyl-2h,3h,3ah,3bh,4h,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-7-yl)oxy]-4-methoxy-6-methyl-2,6-dihydropyran-3-one (NP0275963)

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Record Information

Version

2.0

Created at

2022-09-08 23:52:59 UTC

Updated at

2022-09-08 23:52:59 UTC

NP-MRD ID

NP0275963

Secondary Accession Numbers

None

Natural Product Identification

Common Name

2-[(1-{1-[(4,5-dihydroxy-6-methyloxan-2-yl)oxy]ethyl}-1-hydroxy-9a,11a-dimethyl-2h,3h,3ah,3bh,4h,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-7-yl)oxy]-4-methoxy-6-methyl-2,6-dihydropyran-3-one

Description

2-[(14-{1-[(4,5-Dihydroxy-6-methyloxan-2-yl)oxy]ethyl}-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]Heptadec-7-en-5-yl)oxy]-4-methoxy-6-methyl-3,6-dihydro-2H-pyran-3-one belongs to the class of organic compounds known as steroidal glycosides. These are sterol lipids containing a carbohydrate moiety glycosidically linked to the steroid skeleton. 2-[(1-{1-[(4,5-dihydroxy-6-methyloxan-2-yl)oxy]ethyl}-1-hydroxy-9a,11a-dimethyl-2h,3h,3ah,3bh,4h,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-7-yl)oxy]-4-methoxy-6-methyl-2,6-dihydropyran-3-one is found in Periploca sepium. 2-[(14-{1-[(4,5-Dihydroxy-6-methyloxan-2-yl)oxy]ethyl}-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]Heptadec-7-en-5-yl)oxy]-4-methoxy-6-methyl-3,6-dihydro-2H-pyran-3-one is an extremely weak basic (essentially neutral) compound (based on its pKa).

Structure

MOL SDF PDB SMILES InChI


  Mrv1533004161518182D          

 43 48  0  0  0  0            999 V2000
   -0.6870   -5.9421    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4067   -5.1662    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9385   -4.5355    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7507   -4.6807    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2825   -4.0500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0946   -4.1952    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0022   -3.2741    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1901   -3.1289    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9098   -2.3529    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0976   -2.2077    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1827   -1.4318    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9948   -1.2866    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5266   -1.9173    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8069   -1.1414    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3387   -1.7721    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6190   -0.9961    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4311   -0.8509    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9629   -1.4816    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3228   -0.7393    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6826   -2.2576    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3340   -2.7639    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0168   -2.3009    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7875   -1.5084    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.5484   -1.1896    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.9089   -0.6924    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.6763   -0.3896    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2629   -0.1793    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.3843    0.6367    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.7383    1.1499    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.8597    1.9659    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2137    2.4791    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.6271    2.2688    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7485    3.0848    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.2731    1.7556    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0405    2.0585    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.1517    0.9396    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.8705   -2.4028    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5902   -3.1787    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7781   -3.3239    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2463   -2.6932    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4342   -2.8384    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6582   -3.7596    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1539   -3.6143    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  5  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  1  0  0  0  0
 10 11  1  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 13 15  1  0  0  0  0
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 18 20  1  0  0  0  0
 20 21  1  0  0  0  0
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 22 23  1  0  0  0  0
 18 23  1  0  0  0  0
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 20 37  1  0  0  0  0
 15 37  1  0  0  0  0
 37 38  1  0  0  0  0
 38 39  1  0  0  0  0
 39 40  2  0  0  0  0
 13 40  1  0  0  0  0
 40 41  1  0  0  0  0
 10 41  1  0  0  0  0
  8 42  1  0  0  0  0
  3 42  1  0  0  0  0
 42 43  2  0  0  0  0
M  END


  Mrv1533004161518182D          

 43 48  0  0  0  0            999 V2000
   -0.6870   -5.9421    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4067   -5.1662    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9385   -4.5355    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7507   -4.6807    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2825   -4.0500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0946   -4.1952    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0022   -3.2741    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1901   -3.1289    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9098   -2.3529    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0976   -2.2077    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1827   -1.4318    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9948   -1.2866    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5266   -1.9173    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8069   -1.1414    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3387   -1.7721    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6190   -0.9961    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4311   -0.8509    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9629   -1.4816    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3228   -0.7393    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6826   -2.2576    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3340   -2.7639    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0168   -2.3009    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7875   -1.5084    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.5484   -1.1896    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.9089   -0.6924    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.6763   -0.3896    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2629   -0.1793    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.3843    0.6367    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.7383    1.1499    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.8597    1.9659    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2137    2.4791    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.6271    2.2688    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7485    3.0848    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.2731    1.7556    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0405    2.0585    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.1517    0.9396    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.8705   -2.4028    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5902   -3.1787    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7781   -3.3239    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2463   -2.6932    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4342   -2.8384    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6582   -3.7596    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1539   -3.6143    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  5  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  1  0  0  0  0
 10 11  1  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 13 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  1  0  0  0  0
 18 19  1  0  0  0  0
 18 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  1  0  0  0  0
 18 23  1  0  0  0  0
 23 24  1  0  0  0  0
 23 25  1  0  0  0  0
 25 26  1  0  0  0  0
 25 27  1  0  0  0  0
 27 28  1  0  0  0  0
 28 29  1  0  0  0  0
 29 30  1  0  0  0  0
 30 31  1  0  0  0  0
 30 32  1  0  0  0  0
 32 33  1  0  0  0  0
 32 34  1  0  0  0  0
 34 35  1  0  0  0  0
 34 36  1  0  0  0  0
 28 36  1  0  0  0  0
 20 37  1  0  0  0  0
 15 37  1  0  0  0  0
 37 38  1  0  0  0  0
 38 39  1  0  0  0  0
 39 40  2  0  0  0  0
 13 40  1  0  0  0  0
 40 41  1  0  0  0  0
 10 41  1  0  0  0  0
  8 42  1  0  0  0  0
  3 42  1  0  0  0  0
 42 43  2  0  0  0  0
M  END
> <DATABASE_ID>
NP0275963

> <DATABASE_NAME>
NP-MRD

> <SMILES>
COC1=CC(C)OC(OC2CCC3(C)C4CCC5(C)C(CCC5(O)C(C)OC5CC(O)C(O)C(C)O5)C4CC=C3C2)C1=O

> <INCHI_IDENTIFIER>
InChI=1S/C34H52O9/c1-18-15-27(39-6)30(37)31(40-18)43-22-9-12-32(4)21(16-22)7-8-23-24(32)10-13-33(5)25(23)11-14-34(33,38)20(3)42-28-17-26(35)29(36)19(2)41-28/h7,15,18-20,22-26,28-29,31,35-36,38H,8-14,16-17H2,1-6H3

> <INCHI_KEY>
CGUNKFNCRCGQRL-UHFFFAOYSA-N

> <FORMULA>
C34H52O9

> <MOLECULAR_WEIGHT>
604.781

> <EXACT_MASS>
604.361133254

> <JCHEM_ACCEPTOR_COUNT>
9

> <JCHEM_ATOM_COUNT>
95

> <JCHEM_AVERAGE_POLARIZABILITY>
68.06322721762342

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
3

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
2-[(14-{1-[(4,5-dihydroxy-6-methyloxan-2-yl)oxy]ethyl}-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-7-en-5-yl)oxy]-4-methoxy-6-methyl-3,6-dihydro-2H-pyran-3-one

> <ALOGPS_LOGP>
3.82

> <JCHEM_LOGP>
3.8217322576666675

> <ALOGPS_LOGS>
-5.13

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
6

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
13.625181060121179

> <JCHEM_PKA_STRONGEST_ACIDIC>
12.981862835025336

> <JCHEM_PKA_STRONGEST_BASIC>
-3.2525593911592043

> <JCHEM_POLAR_SURFACE_AREA>
123.91000000000003

> <JCHEM_REFRACTIVITY>
160.74930000000003

> <JCHEM_ROTATABLE_BOND_COUNT>
6

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
4.52e-03 g/l

> <JCHEM_TRADITIONAL_IUPAC>
2-[(14-{1-[(4,5-dihydroxy-6-methyloxan-2-yl)oxy]ethyl}-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-7-en-5-yl)oxy]-4-methoxy-6-methyl-2,6-dihydropyran-3-one

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 16-APR-15   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   16-APR-15         0                                  
HETATM    1  C   UNK     0      -1.282 -11.092   0.000  0.00  0.00           C+0
HETATM    2  O   UNK     0      -0.759  -9.644   0.000  0.00  0.00           O+0
HETATM    3  C   UNK     0      -1.752  -8.466   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      -3.268  -8.737   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      -4.261  -7.560   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0      -5.777  -7.831   0.000  0.00  0.00           C+0
HETATM    7  O   UNK     0      -3.737  -6.112   0.000  0.00  0.00           O+0
HETATM    8  C   UNK     0      -2.221  -5.841   0.000  0.00  0.00           C+0
HETATM    9  O   UNK     0      -1.698  -4.392   0.000  0.00  0.00           O+0
HETATM   10  C   UNK     0      -0.182  -4.121   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       0.341  -2.673   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       1.857  -2.402   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       2.850  -3.579   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       3.373  -2.131   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       4.366  -3.308   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       4.889  -1.859   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       6.405  -1.588   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       7.398  -2.766   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       8.069  -1.380   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0       6.874  -4.214   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0       8.090  -5.159   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0       9.365  -4.295   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0       8.937  -2.816   0.000  0.00  0.00           C+0
HETATM   24  O   UNK     0      10.357  -2.221   0.000  0.00  0.00           O+0
HETATM   25  C   UNK     0       9.163  -1.293   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0      10.596  -0.727   0.000  0.00  0.00           C+0
HETATM   27  O   UNK     0       7.957  -0.335   0.000  0.00  0.00           O+0
HETATM   28  C   UNK     0       8.184   1.189   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0       6.978   2.146   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0       7.205   3.670   0.000  0.00  0.00           C+0
HETATM   31  O   UNK     0       5.999   4.628   0.000  0.00  0.00           O+0
HETATM   32  C   UNK     0       8.637   4.235   0.000  0.00  0.00           C+0
HETATM   33  O   UNK     0       8.864   5.758   0.000  0.00  0.00           O+0
HETATM   34  C   UNK     0       9.843   3.277   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0      11.276   3.843   0.000  0.00  0.00           C+0
HETATM   36  O   UNK     0       9.617   1.754   0.000  0.00  0.00           O+0
HETATM   37  C   UNK     0       5.358  -4.485   0.000  0.00  0.00           C+0
HETATM   38  C   UNK     0       4.835  -5.934   0.000  0.00  0.00           C+0
HETATM   39  C   UNK     0       3.319  -6.205   0.000  0.00  0.00           C+0
HETATM   40  C   UNK     0       2.326  -5.027   0.000  0.00  0.00           C+0
HETATM   41  C   UNK     0       0.810  -5.298   0.000  0.00  0.00           C+0
HETATM   42  C   UNK     0      -1.229  -7.018   0.000  0.00  0.00           C+0
HETATM   43  O   UNK     0       0.287  -6.747   0.000  0.00  0.00           O+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4   42                                                  
CONECT    4    3    5                                                       
CONECT    5    4    6    7                                                  
CONECT    6    5                                                            
CONECT    7    5    8                                                       
CONECT    8    7    9   42                                                  
CONECT    9    8   10                                                       
CONECT   10    9   11   41                                                  
CONECT   11   10   12                                                       
CONECT   12   11   13                                                       
CONECT   13   12   14   15   40                                             
CONECT   14   13                                                            
CONECT   15   13   16   37                                                  
CONECT   16   15   17                                                       
CONECT   17   16   18                                                       
CONECT   18   17   19   20   23                                             
CONECT   19   18                                                            
CONECT   20   18   21   37                                                  
CONECT   21   20   22                                                       
CONECT   22   21   23                                                       
CONECT   23   22   18   24   25                                             
CONECT   24   23                                                            
CONECT   25   23   26   27                                                  
CONECT   26   25                                                            
CONECT   27   25   28                                                       
CONECT   28   27   29   36                                                  
CONECT   29   28   30                                                       
CONECT   30   29   31   32                                                  
CONECT   31   30                                                            
CONECT   32   30   33   34                                                  
CONECT   33   32                                                            
CONECT   34   32   35   36                                                  
CONECT   35   34                                                            
CONECT   36   34   28                                                       
CONECT   37   20   15   38                                                  
CONECT   38   37   39                                                       
CONECT   39   38   40                                                       
CONECT   40   39   13   41                                                  
CONECT   41   40   10                                                       
CONECT   42    8    3   43                                                  
CONECT   43   42                                                            
MASTER        0    0    0    0    0    0    0    0   43    0   96    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₃₄H₅₂O₉

Average Mass

604.7810 Da

Monoisotopic Mass

604.36113 Da

IUPAC Name

2-[(14-{1-[(4,5-dihydroxy-6-methyloxan-2-yl)oxy]ethyl}-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-7-en-5-yl)oxy]-4-methoxy-6-methyl-3,6-dihydro-2H-pyran-3-one

Traditional Name

2-[(14-{1-[(4,5-dihydroxy-6-methyloxan-2-yl)oxy]ethyl}-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-7-en-5-yl)oxy]-4-methoxy-6-methyl-2,6-dihydropyran-3-one

CAS Registry Number

Not Available

SMILES

COC1=CC(C)OC(OC2CCC3(C)C4CCC5(C)C(CCC5(O)C(C)OC5CC(O)C(O)C(C)O5)C4CC=C3C2)C1=O

InChI Identifier

InChI=1S/C34H52O9/c1-18-15-27(39-6)30(37)31(40-18)43-22-9-12-32(4)21(16-22)7-8-23-24(32)10-13-33(5)25(23)11-14-34(33,38)20(3)42-28-17-26(35)29(36)19(2)41-28/h7,15,18-20,22-26,28-29,31,35-36,38H,8-14,16-17H2,1-6H3

InChI Key

CGUNKFNCRCGQRL-UHFFFAOYSA-N

Experimental Spectra

Not Available

Predicted Spectra

Not Available

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Periploca sepium	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as steroidal glycosides. These are sterol lipids containing a carbohydrate moiety glycosidically linked to the steroid skeleton.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Steroids and steroid derivatives

Sub Class

Steroidal glycosides

Direct Parent

Steroidal glycosides

Alternative Parents

Substituents

Steroidal glycoside
Pregnane-skeleton
Hydroxysteroid
17-hydroxysteroid
Delta-5-steroid
Glycosyl compound
O-glycosyl compound
Dihydropyranone
Monosaccharide
Oxane
Pyran
Cyclic alcohol
Tertiary alcohol
Ketone
Secondary alcohol
Cyclic ketone
Organoheterocyclic compound
Acetal
Oxacycle
Alcohol
Organooxygen compound
Hydrocarbon derivative
Organic oxide
Organic oxygen compound
Carbonyl group
Aliphatic heteropolycyclic compound

Molecular Framework

Aliphatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	3.82	ALOGPS
logP	3.82	ChemAxon
logS	-5.1	ALOGPS
pKa (Strongest Acidic)	12.98	ChemAxon
pKa (Strongest Basic)	-3.3	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	9	ChemAxon
Hydrogen Donor Count	3	ChemAxon
Polar Surface Area	123.91 Å²	ChemAxon
Rotatable Bond Count	6	ChemAxon
Refractivity	160.75 m³·mol⁻¹	ChemAxon
Polarizability	68.06 Å³	ChemAxon
Number of Rings	6	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	Yes	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

Not Available

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for 2-[(1-{1-[(4,5-dihydroxy-6-methyloxan-2-yl)oxy]ethyl}-1-hydroxy-9a,11a-dimethyl-2h,3h,3ah,3bh,4h,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-7-yl)oxy]-4-methoxy-6-methyl-2,6-dihydropyran-3-one (NP0275963)

MOL for NP0275963 (2-[(1-{1-[(4,5-dihydroxy-6-methyloxan-2-yl)oxy]ethyl}-1-hydroxy-9a,11a-dimethyl-2h,3h,3ah,3bh,4h,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-7-yl)oxy]-4-methoxy-6-methyl-2,6-dihydropyran-3-one)

3D MOL for NP0275963 (2-[(1-{1-[(4,5-dihydroxy-6-methyloxan-2-yl)oxy]ethyl}-1-hydroxy-9a,11a-dimethyl-2h,3h,3ah,3bh,4h,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-7-yl)oxy]-4-methoxy-6-methyl-2,6-dihydropyran-3-one)

3D SDF for NP0275963 (2-[(1-{1-[(4,5-dihydroxy-6-methyloxan-2-yl)oxy]ethyl}-1-hydroxy-9a,11a-dimethyl-2h,3h,3ah,3bh,4h,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-7-yl)oxy]-4-methoxy-6-methyl-2,6-dihydropyran-3-one)

3D-SDF for NP0275963 (2-[(1-{1-[(4,5-dihydroxy-6-methyloxan-2-yl)oxy]ethyl}-1-hydroxy-9a,11a-dimethyl-2h,3h,3ah,3bh,4h,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-7-yl)oxy]-4-methoxy-6-methyl-2,6-dihydropyran-3-one)

PDB for NP0275963 (2-[(1-{1-[(4,5-dihydroxy-6-methyloxan-2-yl)oxy]ethyl}-1-hydroxy-9a,11a-dimethyl-2h,3h,3ah,3bh,4h,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-7-yl)oxy]-4-methoxy-6-methyl-2,6-dihydropyran-3-one)

3D PDB for NP0275963 (2-[(1-{1-[(4,5-dihydroxy-6-methyloxan-2-yl)oxy]ethyl}-1-hydroxy-9a,11a-dimethyl-2h,3h,3ah,3bh,4h,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-7-yl)oxy]-4-methoxy-6-methyl-2,6-dihydropyran-3-one)

SMILES for NP0275963 (2-[(1-{1-[(4,5-dihydroxy-6-methyloxan-2-yl)oxy]ethyl}-1-hydroxy-9a,11a-dimethyl-2h,3h,3ah,3bh,4h,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-7-yl)oxy]-4-methoxy-6-methyl-2,6-dihydropyran-3-one)

INCHI for NP0275963 (2-[(1-{1-[(4,5-dihydroxy-6-methyloxan-2-yl)oxy]ethyl}-1-hydroxy-9a,11a-dimethyl-2h,3h,3ah,3bh,4h,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-7-yl)oxy]-4-methoxy-6-methyl-2,6-dihydropyran-3-one)

Structure for NP0275963 (2-[(1-{1-[(4,5-dihydroxy-6-methyloxan-2-yl)oxy]ethyl}-1-hydroxy-9a,11a-dimethyl-2h,3h,3ah,3bh,4h,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-7-yl)oxy]-4-methoxy-6-methyl-2,6-dihydropyran-3-one)

3D Structure for NP0275963 (2-[(1-{1-[(4,5-dihydroxy-6-methyloxan-2-yl)oxy]ethyl}-1-hydroxy-9a,11a-dimethyl-2h,3h,3ah,3bh,4h,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-7-yl)oxy]-4-methoxy-6-methyl-2,6-dihydropyran-3-one)