NP-MRD: Showing NP-Card for (2z)-6-hydroxy-2-[(4-hydroxy-3-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)methylidene]-1-benzofuran-3-one (NP0272365)

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Record Information

Version

2.0

Created at

2022-09-08 18:57:31 UTC

Updated at

2022-09-08 18:57:31 UTC

NP-MRD ID

NP0272365

Secondary Accession Numbers

None

Natural Product Identification

Common Name

(2z)-6-hydroxy-2-[(4-hydroxy-3-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)methylidene]-1-benzofuran-3-one

Description

6-Hydroxy-2-[3-(beta-D-glucopyranosyloxy)-4-hydroxybenzylidene]benzofuran-3(2H)-one belongs to the class of organic compounds known as aurone flavonoids. These are flavonoids containing a 2-Benzylidene-1-benzofuran-3-one based core. Aurone flavonoids provide the bright yellow color of some important ornamental flowers, such as snapdragon (Antirrhinum majus). (2z)-6-hydroxy-2-[(4-hydroxy-3-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)methylidene]-1-benzofuran-3-one is found in Butea monosperma. Based on a literature review very few articles have been published on 6-Hydroxy-2-[3-(beta-D-glucopyranosyloxy)-4-hydroxybenzylidene]benzofuran-3(2H)-one.

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652309082220572D          

 31 34  0  0  1  0            999 V2000
    0.8838   -2.1500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.1387   -1.3654    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6538   -0.6979    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1712   -0.6979    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5837    0.0165    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4087    0.0165    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8212    0.7310    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4087    1.4455    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8212    2.1599    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5837    1.4455    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1712    2.1599    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5837    2.8744    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -1.4087    2.8744    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8212    3.5889    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -2.6462    3.5889    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0587    4.3034    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4087    4.3034    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.8212    5.0178    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5837    4.3034    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.1712    5.0178    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1712    3.5889    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.6538    3.5889    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1712    0.7310    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1387   -0.0305    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.9233   -0.2854    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6378    0.1271    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3523   -0.2854    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0668    0.1271    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.3523   -1.1104    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6378   -1.5229    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9233   -1.1104    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  4  5  1  0  0  0  0
  5  6  2  0  0  0  0
  6  7  1  0  0  0  0
  7  8  2  0  0  0  0
  8  9  1  0  0  0  0
  8 10  1  0  0  0  0
 10 11  1  0  0  0  0
 12 11  1  6  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  6  0  0  0
 15 16  1  0  0  0  0
 14 17  1  0  0  0  0
 17 18  1  1  0  0  0
 17 19  1  0  0  0  0
 19 20  1  6  0  0  0
 19 21  1  0  0  0  0
 12 21  1  0  0  0  0
 21 22  1  1  0  0  0
 10 23  2  0  0  0  0
  5 23  1  0  0  0  0
  3 24  1  0  0  0  0
 24 25  1  0  0  0  0
 25 26  2  0  0  0  0
 26 27  1  0  0  0  0
 27 28  1  0  0  0  0
 27 29  2  0  0  0  0
 29 30  1  0  0  0  0
 30 31  2  0  0  0  0
 25 31  1  0  0  0  0
  2 31  1  0  0  0  0
M  END

     RDKit          3D

 51 54  0  0  0  0  0  0  0  0999 V2000
    4.4941   -1.7653   -2.7407 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.6343   -1.0555   -1.7373 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6249   -0.8256   -0.7092 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3924   -1.2902   -0.6061 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5136   -0.9442    0.5139 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9912   -0.8084    1.8012 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1918   -0.4848    2.8786 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1566   -0.2834    2.6751 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9750    0.0446    3.7589 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6901   -0.4087    1.3907 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0290   -0.1935    1.2751 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8127   -0.2551    0.1024 C   0  0  2  0  0  0  0  0  0  0  0  0
   -3.3451    1.0041   -0.0821 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3923    1.0906   -0.9522 C   0  0  2  0  0  0  0  0  0  0  0  0
   -4.8518    2.5509   -0.9599 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.9351    2.7086   -1.8414 O   0  0  0  0  0  0  0  0  0  0  0  0
   -5.5537    0.2946   -0.3421 C   0  0  1  0  0  0  0  0  0  0  0  0
   -6.7330    0.4952   -1.0237 O   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1089   -1.1657   -0.4343 C   0  0  2  0  0  0  0  0  0  0  0  0
   -6.0861   -1.9798    0.1578 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8319   -1.3427    0.3072 C   0  0  1  0  0  0  0  0  0  0  0  0
   -3.2558   -2.5599   -0.1268 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.1476   -0.7338    0.3444 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2311    0.0260    0.2038 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.5127    0.3374   -0.1689 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4379    1.1478    0.4674 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.6849    1.3237   -0.0919 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.6376    2.1437    0.5406 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.0122    0.7097   -1.2594 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.0784   -0.1085   -1.9021 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.8265   -0.3009   -1.3650 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0292   -1.9444   -1.3740 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.0503   -0.9677    1.9538 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.5737   -0.3793    3.8904 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9655    0.1950    3.6199 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2425   -0.5174   -0.8085 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.2223    0.7258   -1.9646 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0124    3.2382   -1.2111 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.2204    2.8522    0.0414 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1803    3.6656   -1.8034 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.7034    0.6065    0.7087 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.5044    0.6297   -0.4029 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.0488   -1.3932   -1.5106 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.0261   -2.9104   -0.2117 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0689   -1.3998    1.3986 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9209   -3.1021   -0.6447 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2439   -0.8371   -0.6584 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.2300    1.6561    1.3918 H   0  0  0  0  0  0  0  0  0  0  0  0
    9.5439    2.2938    0.1676 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.9888    0.8343   -1.7158 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.2895   -0.6167   -2.8305 H   0  0  0  0  0  0  0  0  0  0  0  0
 16 15  1  0
 15 14  1  0
 14 13  1  0
 13 12  1  0
 12 11  1  0
 11 10  1  0
 10 23  2  0
 23  5  1  0
  5  4  1  0
  4  3  2  0
  3 24  1  0
 24 25  1  0
 25 26  2  0
 26 27  1  0
 27 28  1  0
 27 29  2  0
 29 30  1  0
 30 31  2  0
 31  2  1  0
  2  1  2  0
  5  6  2  0
  6  7  1  0
  7  8  2  0
  8  9  1  0
 12 21  1  0
 21 22  1  0
 21 19  1  0
 19 20  1  0
 19 17  1  0
 17 18  1  0
 17 14  1  0
  8 10  1  0
  2  3  1  0
 31 25  1  0
 16 40  1  0
 15 38  1  0
 15 39  1  0
 14 37  1  6
 12 36  1  6
 23 47  1  0
  4 32  1  0
 26 48  1  0
 28 49  1  0
 29 50  1  0
 30 51  1  0
  6 33  1  0
  7 34  1  0
  9 35  1  0
 21 45  1  1
 22 46  1  0
 19 43  1  6
 20 44  1  0
 17 41  1  1
 18 42  1  0
M  END


  Mrv1652309082220572D          

 31 34  0  0  1  0            999 V2000
    0.8838   -2.1500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.1387   -1.3654    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6538   -0.6979    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1712   -0.6979    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5837    0.0165    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4087    0.0165    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8212    0.7310    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4087    1.4455    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8212    2.1599    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5837    1.4455    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1712    2.1599    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5837    2.8744    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -1.4087    2.8744    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8212    3.5889    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -2.6462    3.5889    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0587    4.3034    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4087    4.3034    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.8212    5.0178    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5837    4.3034    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.1712    5.0178    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1712    3.5889    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.6538    3.5889    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1712    0.7310    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1387   -0.0305    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.9233   -0.2854    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6378    0.1271    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3523   -0.2854    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0668    0.1271    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.3523   -1.1104    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6378   -1.5229    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9233   -1.1104    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  4  5  1  0  0  0  0
  5  6  2  0  0  0  0
  6  7  1  0  0  0  0
  7  8  2  0  0  0  0
  8  9  1  0  0  0  0
  8 10  1  0  0  0  0
 10 11  1  0  0  0  0
 12 11  1  6  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  6  0  0  0
 15 16  1  0  0  0  0
 14 17  1  0  0  0  0
 17 18  1  1  0  0  0
 17 19  1  0  0  0  0
 19 20  1  6  0  0  0
 19 21  1  0  0  0  0
 12 21  1  0  0  0  0
 21 22  1  1  0  0  0
 10 23  2  0  0  0  0
  5 23  1  0  0  0  0
  3 24  1  0  0  0  0
 24 25  1  0  0  0  0
 25 26  2  0  0  0  0
 26 27  1  0  0  0  0
 27 28  1  0  0  0  0
 27 29  2  0  0  0  0
 29 30  1  0  0  0  0
 30 31  2  0  0  0  0
 25 31  1  0  0  0  0
  2 31  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0272365

> <DATABASE_NAME>
NP-MRD

> <SMILES>
OC[C@H]1O[C@@H](OC2=CC(\C=C3/OC4=CC(O)=CC=C4C3=O)=CC=C2O)[C@H](O)[C@@H](O)[C@@H]1O

> <INCHI_IDENTIFIER>
InChI=1S/C21H20O10/c22-8-16-18(26)19(27)20(28)21(31-16)30-14-5-9(1-4-12(14)24)6-15-17(25)11-3-2-10(23)7-13(11)29-15/h1-7,16,18-24,26-28H,8H2/b15-6-/t16-,18-,19+,20-,21-/m1/s1

> <INCHI_KEY>
PAEWWLDNEFSNIG-LTEMJKMTSA-N

> <FORMULA>
C21H20O10

> <MOLECULAR_WEIGHT>
432.381

> <EXACT_MASS>
432.105646844

> <JCHEM_ACCEPTOR_COUNT>
10

> <JCHEM_ATOM_COUNT>
51

> <JCHEM_AVERAGE_POLARIZABILITY>
41.666945027128946

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
6

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
(2Z)-6-hydroxy-2-[(4-hydroxy-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)methylidene]-2,3-dihydro-1-benzofuran-3-one

> <JCHEM_LOGP>
0.023510258000000284

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
4

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
9.153515630728608

> <JCHEM_PKA_STRONGEST_ACIDIC>
7.638491437290396

> <JCHEM_PKA_STRONGEST_BASIC>
-2.981092354911903

> <JCHEM_POLAR_SURFACE_AREA>
166.14

> <JCHEM_REFRACTIVITY>
105.13340000000001

> <JCHEM_ROTATABLE_BOND_COUNT>
4

> <JCHEM_RULE_OF_FIVE>
0

> <JCHEM_TRADITIONAL_IUPAC>
(2Z)-6-hydroxy-2-[(4-hydroxy-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)methylidene]-1-benzofuran-3-one

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 08-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   08-SEP-22         0                                  
HETATM    1  O   UNK     0       1.650  -4.013   0.000  0.00  0.00           O+0
HETATM    2  C   UNK     0       2.126  -2.549   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       1.220  -1.303   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      -0.320  -1.303   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      -1.090   0.031   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0      -2.630   0.031   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0      -3.400   1.365   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0      -2.630   2.698   0.000  0.00  0.00           C+0
HETATM    9  O   UNK     0      -3.400   4.032   0.000  0.00  0.00           O+0
HETATM   10  C   UNK     0      -1.090   2.698   0.000  0.00  0.00           C+0
HETATM   11  O   UNK     0      -0.320   4.032   0.000  0.00  0.00           O+0
HETATM   12  C   UNK     0      -1.090   5.366   0.000  0.00  0.00           C+0
HETATM   13  O   UNK     0      -2.630   5.366   0.000  0.00  0.00           O+0
HETATM   14  C   UNK     0      -3.400   6.699   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0      -4.940   6.699   0.000  0.00  0.00           C+0
HETATM   16  O   UNK     0      -5.710   8.033   0.000  0.00  0.00           O+0
HETATM   17  C   UNK     0      -2.630   8.033   0.000  0.00  0.00           C+0
HETATM   18  O   UNK     0      -3.400   9.367   0.000  0.00  0.00           O+0
HETATM   19  C   UNK     0      -1.090   8.033   0.000  0.00  0.00           C+0
HETATM   20  O   UNK     0      -0.320   9.367   0.000  0.00  0.00           O+0
HETATM   21  C   UNK     0      -0.320   6.699   0.000  0.00  0.00           C+0
HETATM   22  O   UNK     0       1.220   6.699   0.000  0.00  0.00           O+0
HETATM   23  C   UNK     0      -0.320   1.365   0.000  0.00  0.00           C+0
HETATM   24  O   UNK     0       2.126  -0.057   0.000  0.00  0.00           O+0
HETATM   25  C   UNK     0       3.590  -0.533   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0       4.924   0.237   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0       6.258  -0.533   0.000  0.00  0.00           C+0
HETATM   28  O   UNK     0       7.591   0.237   0.000  0.00  0.00           O+0
HETATM   29  C   UNK     0       6.258  -2.073   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0       4.924  -2.843   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0       3.590  -2.073   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3   31                                                  
CONECT    3    2    4   24                                                  
CONECT    4    3    5                                                       
CONECT    5    4    6   23                                                  
CONECT    6    5    7                                                       
CONECT    7    6    8                                                       
CONECT    8    7    9   10                                                  
CONECT    9    8                                                            
CONECT   10    8   11   23                                                  
CONECT   11   10   12                                                       
CONECT   12   11   13   21                                                  
CONECT   13   12   14                                                       
CONECT   14   13   15   17                                                  
CONECT   15   14   16                                                       
CONECT   16   15                                                            
CONECT   17   14   18   19                                                  
CONECT   18   17                                                            
CONECT   19   17   20   21                                                  
CONECT   20   19                                                            
CONECT   21   19   12   22                                                  
CONECT   22   21                                                            
CONECT   23   10    5                                                       
CONECT   24    3   25                                                       
CONECT   25   24   26   31                                                  
CONECT   26   25   27                                                       
CONECT   27   26   28   29                                                  
CONECT   28   27                                                            
CONECT   29   27   30                                                       
CONECT   30   29   31                                                       
CONECT   31   30   25    2                                                  
MASTER        0    0    0    0    0    0    0    0   31    0   68    0
END

View in JSmol

Synonyms

Value	Source
6-Hydroxy-2-[3-(b-D-glucopyranosyloxy)-4-hydroxybenzylidene]benzofuran-3(2H)-one	Generator
6-Hydroxy-2-[3-(β-D-glucopyranosyloxy)-4-hydroxybenzylidene]benzofuran-3(2H)-one	Generator

Chemical Formula

C₂₁H₂₀O₁₀

Average Mass

432.3810 Da

Monoisotopic Mass

432.10565 Da

IUPAC Name

(2Z)-6-hydroxy-2-[(4-hydroxy-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)methylidene]-2,3-dihydro-1-benzofuran-3-one

Traditional Name

(2Z)-6-hydroxy-2-[(4-hydroxy-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)methylidene]-1-benzofuran-3-one

CAS Registry Number

Not Available

SMILES

OC[C@H]1O[C@@H](OC2=CC(\C=C3/OC4=CC(O)=CC=C4C3=O)=CC=C2O)[C@H](O)[C@@H](O)[C@@H]1O

InChI Identifier

InChI=1S/C21H20O10/c22-8-16-18(26)19(27)20(28)21(31-16)30-14-5-9(1-4-12(14)24)6-15-17(25)11-3-2-10(23)7-13(11)29-15/h1-7,16,18-24,26-28H,8H2/b15-6-/t16-,18-,19+,20-,21-/m1/s1

InChI Key

PAEWWLDNEFSNIG-LTEMJKMTSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Butea monosperma	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as aurone flavonoids. These are flavonoids containing a 2-Benzylidene-1-benzofuran-3-one based core. Aurone flavonoids provide the bright yellow color of some important ornamental flowers, such as snapdragon (Antirrhinum majus).

Kingdom

Organic compounds

Super Class

Phenylpropanoids and polyketides

Class

Aurone flavonoids

Sub Class

Not Available

Direct Parent

Aurone flavonoids

Alternative Parents

Substituents

Aurone
Phenolic glycoside
Hexose monosaccharide
Glycosyl compound
O-glycosyl compound
Benzofuran
Coumaran
Phenoxy compound
Phenol ether
Aryl ketone
1-hydroxy-2-unsubstituted benzenoid
Phenol
Benzenoid
Monocyclic benzene moiety
Monosaccharide
Oxane
Ketone
Secondary alcohol
Acetal
Oxacycle
Organoheterocyclic compound
Polyol
Organooxygen compound
Hydrocarbon derivative
Organic oxide
Organic oxygen compound
Alcohol
Primary alcohol
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	0.024	ChemAxon
pKa (Strongest Acidic)	7.64	ChemAxon
pKa (Strongest Basic)	-3	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	10	ChemAxon
Hydrogen Donor Count	6	ChemAxon
Polar Surface Area	166.14 Å²	ChemAxon
Rotatable Bond Count	4	ChemAxon
Refractivity	105.13 m³·mol⁻¹	ChemAxon
Polarizability	41.67 Å³	ChemAxon
Number of Rings	4	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

54597953

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for (2z)-6-hydroxy-2-[(4-hydroxy-3-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)methylidene]-1-benzofuran-3-one (NP0272365)

MOL for NP0272365 ((2z)-6-hydroxy-2-[(4-hydroxy-3-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)methylidene]-1-benzofuran-3-one)

3D MOL for NP0272365 ((2z)-6-hydroxy-2-[(4-hydroxy-3-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)methylidene]-1-benzofuran-3-one)

3D SDF for NP0272365 ((2z)-6-hydroxy-2-[(4-hydroxy-3-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)methylidene]-1-benzofuran-3-one)

3D-SDF for NP0272365 ((2z)-6-hydroxy-2-[(4-hydroxy-3-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)methylidene]-1-benzofuran-3-one)

PDB for NP0272365 ((2z)-6-hydroxy-2-[(4-hydroxy-3-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)methylidene]-1-benzofuran-3-one)

3D PDB for NP0272365 ((2z)-6-hydroxy-2-[(4-hydroxy-3-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)methylidene]-1-benzofuran-3-one)

SMILES for NP0272365 ((2z)-6-hydroxy-2-[(4-hydroxy-3-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)methylidene]-1-benzofuran-3-one)

INCHI for NP0272365 ((2z)-6-hydroxy-2-[(4-hydroxy-3-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)methylidene]-1-benzofuran-3-one)

Structure for NP0272365 ((2z)-6-hydroxy-2-[(4-hydroxy-3-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)methylidene]-1-benzofuran-3-one)

3D Structure for NP0272365 ((2z)-6-hydroxy-2-[(4-hydroxy-3-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)methylidene]-1-benzofuran-3-one)