NP-MRD: Showing NP-Card for 1-{3-[(5-acetyl-2,4,6-trihydroxy-3,3-dimethylcyclohexa-1,4-dien-1-yl)methyl]-2,4,6-trihydroxy-5-methylphenyl}butan-1-one (NP0271815)

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Record Information

Version

2.0

Created at

2022-09-08 18:13:50 UTC

Updated at

2022-09-08 18:13:50 UTC

NP-MRD ID

NP0271815

Secondary Accession Numbers

None

Natural Product Identification

Common Name

1-{3-[(5-acetyl-2,4,6-trihydroxy-3,3-dimethylcyclohexa-1,4-dien-1-yl)methyl]-2,4,6-trihydroxy-5-methylphenyl}butan-1-one

Description

1-{3-[(5-Acetyl-2,4,6-trihydroxy-3,3-dimethylcyclohexa-1,4-dien-1-yl)methyl]-2,4,6-trihydroxy-5-methylphenyl}butan-1-one belongs to the class of organic compounds known as alkyl-phenylketones. These are aromatic compounds containing a ketone substituted by one alkyl group, and a phenyl group. 1-{3-[(5-acetyl-2,4,6-trihydroxy-3,3-dimethylcyclohexa-1,4-dien-1-yl)methyl]-2,4,6-trihydroxy-5-methylphenyl}butan-1-one is found in Dryopteris sieboldii. 1-{3-[(5-Acetyl-2,4,6-trihydroxy-3,3-dimethylcyclohexa-1,4-dien-1-yl)methyl]-2,4,6-trihydroxy-5-methylphenyl}butan-1-one is an extremely weak basic (essentially neutral) compound (based on its pKa).

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1533004171500372D          

 30 31  0  0  0  0            999 V2000
   -2.1434    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    0.0000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1434   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1434   -2.8875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -2.8875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -3.7125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -2.8875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6131   -0.6055    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6737   -0.6055    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -2.8875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -3.7125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -2.8875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868   -2.4750    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -3.7125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3356   -0.8963    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  1  0  0  0  0
  4  5  2  0  0  0  0
  4  6  1  0  0  0  0
  6  7  2  0  0  0  0
  7  8  1  0  0  0  0
  7  9  1  0  0  0  0
  9 10  1  0  0  0  0
  9 11  2  0  0  0  0
 11 12  1  0  0  0  0
 11 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  2  0  0  0  0
 16 17  1  0  0  0  0
 16 18  1  0  0  0  0
 18 19  1  0  0  0  0
 18 20  1  0  0  0  0
 18 21  1  0  0  0  0
 21 22  2  0  0  0  0
 22 23  1  0  0  0  0
 15 23  1  0  0  0  0
 23 24  1  0  0  0  0
 22 25  1  0  0  0  0
 25 26  2  0  0  0  0
 25 27  1  0  0  0  0
 21 28  1  0  0  0  0
 13 29  2  0  0  0  0
  6 29  1  0  0  0  0
 29 30  1  0  0  0  0
M  END

     RDKit          3D

 58 59  0  0  0  0  0  0  0  0999 V2000
    6.4752   -0.0041    2.2548 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9840    1.2954    1.7069 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0565    1.0657    0.5284 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.8793    0.2671    0.9243 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.7944   -0.0998    2.1218 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.8544   -0.0765   -0.0598 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.9339    0.3139   -1.3600 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0167    1.0720   -1.8104 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.9440   -0.0284   -2.2724 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1044    0.4349   -3.6700 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8586   -0.7666   -1.9000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1591   -1.1459   -2.7347 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7826   -1.1663   -0.5569 C   0  0  0  0  0  0  0  0  0  0  0  0
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   -1.6072   -1.1730    0.1044 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6922   -1.4644   -0.5860 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6308   -2.5102   -1.5038 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9715   -0.7645   -0.4607 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5743   -0.4680   -1.8252 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9528   -1.6374    0.3065 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8678    0.5203    0.2992 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9216    1.4383    0.2804 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8038    0.8159    0.9916 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7291    2.0699    1.7236 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8042    3.0881    1.7549 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6759    2.3161    2.3821 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6216   -0.0897    1.0808 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.5335   -0.5668    2.4044 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.7495   -0.8382    0.3598 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7422   -1.1939    1.6978 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.5865   -0.1177    2.1511 H   0  0  0  0  0  0  0  0  0  0  0  0
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    5.5307    1.9652    2.4481 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.8719    1.8450    1.2889 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.7731    2.0717    0.1515 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.6777    0.5824   -0.2536 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.1203    1.3717   -2.7560 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.3037    1.5478   -3.6681 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.0252   -0.0094   -4.1161 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.2061    0.2270   -4.2437 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2964   -0.9744   -3.6919 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1321   -2.5527    0.7639 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5401   -2.7176   -0.9389 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7762   -3.4897   -1.2188 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.6593   -0.3661   -1.6717 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.2854   -1.2683   -2.5072 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1771    0.5351   -2.1236 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5353   -1.8779    1.3022 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1119   -2.6013   -0.2223 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.9106   -1.1007    0.4709 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.8476    1.1793    0.6435 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.7189    2.6647    2.2195 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0474    3.5166    0.7622 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4844    3.9623    2.3719 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7353    0.5968    0.9839 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3283   -1.0844    2.6116 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.9964   -1.7229    2.0852 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  1  0
  4  5  2  0
  4  6  1  0
  6  7  2  0
  7  8  1  0
  7  9  1  0
  9 10  1  0
  9 11  2  0
 11 12  1  0
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 13 14  1  0
 14 15  1  0
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 16 17  1  0
 16 18  1  0
 18 19  1  0
 18 20  1  0
 18 21  1  0
 21 22  1  0
 21 23  2  0
 23 27  1  0
 27 28  1  0
 23 24  1  0
 24 25  1  0
 24 26  2  0
 13 29  2  0
 29 30  1  0
 29  6  1  0
 27 15  1  0
  1 31  1  0
  1 32  1  0
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  2 34  1  0
  2 35  1  0
  3 36  1  0
  3 37  1  0
  8 38  1  0
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 17 45  1  0
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 19 47  1  0
 19 48  1  0
 20 49  1  0
 20 50  1  0
 20 51  1  0
 22 52  1  0
 27 56  1  6
 28 57  1  0
 25 53  1  0
 25 54  1  0
 25 55  1  0
 30 58  1  0
M  END


  Mrv1533004171500372D          

 30 31  0  0  0  0            999 V2000
   -2.1434    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    0.0000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1434   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1434   -2.8875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -2.8875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -3.7125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -2.8875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6131   -0.6055    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6737   -0.6055    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -2.8875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -3.7125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -2.8875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868   -2.4750    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -3.7125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3356   -0.8963    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  1  0  0  0  0
  4  5  2  0  0  0  0
  4  6  1  0  0  0  0
  6  7  2  0  0  0  0
  7  8  1  0  0  0  0
  7  9  1  0  0  0  0
  9 10  1  0  0  0  0
  9 11  2  0  0  0  0
 11 12  1  0  0  0  0
 11 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  2  0  0  0  0
 16 17  1  0  0  0  0
 16 18  1  0  0  0  0
 18 19  1  0  0  0  0
 18 20  1  0  0  0  0
 18 21  1  0  0  0  0
 21 22  2  0  0  0  0
 22 23  1  0  0  0  0
 15 23  1  0  0  0  0
 23 24  1  0  0  0  0
 22 25  1  0  0  0  0
 25 26  2  0  0  0  0
 25 27  1  0  0  0  0
 21 28  1  0  0  0  0
 13 29  2  0  0  0  0
  6 29  1  0  0  0  0
 29 30  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0271815

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CCCC(=O)C1=C(O)C(C)=C(O)C(CC2=C(O)C(C)(C)C(O)=C(C2O)C(C)=O)=C1O

> <INCHI_IDENTIFIER>
InChI=1S/C22H28O8/c1-6-7-13(24)15-17(26)9(2)16(25)11(18(15)27)8-12-19(28)14(10(3)23)21(30)22(4,5)20(12)29/h19,25-30H,6-8H2,1-5H3

> <INCHI_KEY>
QBTDHAKBGQYTFR-UHFFFAOYSA-N

> <FORMULA>
C22H28O8

> <MOLECULAR_WEIGHT>
420.458

> <EXACT_MASS>
420.178417862

> <JCHEM_ACCEPTOR_COUNT>
8

> <JCHEM_ATOM_COUNT>
58

> <JCHEM_AVERAGE_POLARIZABILITY>
43.263169344960865

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
6

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
1-{3-[(5-acetyl-2,4,6-trihydroxy-3,3-dimethylcyclohexa-1,4-dien-1-yl)methyl]-2,4,6-trihydroxy-5-methylphenyl}butan-1-one

> <ALOGPS_LOGP>
1.94

> <JCHEM_LOGP>
3.305928245666667

> <ALOGPS_LOGS>
-3.06

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
2

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
8.27315488013474

> <JCHEM_PKA_STRONGEST_ACIDIC>
7.453639231696517

> <JCHEM_PKA_STRONGEST_BASIC>
-3.4122681859650337

> <JCHEM_POLAR_SURFACE_AREA>
155.51999999999998

> <JCHEM_REFRACTIVITY>
113.15189999999997

> <JCHEM_ROTATABLE_BOND_COUNT>
6

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
3.66e-01 g/l

> <JCHEM_TRADITIONAL_IUPAC>
1-{3-[(5-acetyl-2,4,6-trihydroxy-3,3-dimethylcyclohexa-1,4-dien-1-yl)methyl]-2,4,6-trihydroxy-5-methylphenyl}butan-1-one

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 17-APR-15   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   17-APR-15         0                                  
HETATM    1  C   UNK     0      -4.001   2.310   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      -2.667   1.540   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      -2.667  -0.000   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      -1.334  -0.770   0.000  0.00  0.00           C+0
HETATM    5  O   UNK     0       0.000   0.000   0.000  0.00  0.00           O+0
HETATM    6  C   UNK     0      -1.334  -2.310   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0      -2.667  -3.080   0.000  0.00  0.00           C+0
HETATM    8  O   UNK     0      -4.001  -2.310   0.000  0.00  0.00           O+0
HETATM    9  C   UNK     0      -2.667  -4.620   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0      -4.001  -5.390   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0      -1.334  -5.390   0.000  0.00  0.00           C+0
HETATM   12  O   UNK     0      -1.334  -6.930   0.000  0.00  0.00           O+0
HETATM   13  C   UNK     0       0.000  -4.620   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       1.334  -5.390   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       2.667  -4.620   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       2.667  -3.080   0.000  0.00  0.00           C+0
HETATM   17  O   UNK     0       1.334  -2.310   0.000  0.00  0.00           O+0
HETATM   18  C   UNK     0       4.001  -2.310   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       3.011  -1.130   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0       4.991  -1.130   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0       5.335  -3.080   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0       5.335  -4.620   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0       4.001  -5.390   0.000  0.00  0.00           C+0
HETATM   24  O   UNK     0       4.001  -6.930   0.000  0.00  0.00           O+0
HETATM   25  C   UNK     0       6.668  -5.390   0.000  0.00  0.00           C+0
HETATM   26  O   UNK     0       8.002  -4.620   0.000  0.00  0.00           O+0
HETATM   27  C   UNK     0       6.668  -6.930   0.000  0.00  0.00           C+0
HETATM   28  O   UNK     0       6.668  -2.310   0.000  0.00  0.00           O+0
HETATM   29  C   UNK     0       0.000  -3.080   0.000  0.00  0.00           C+0
HETATM   30  O   UNK     0       0.626  -1.673   0.000  0.00  0.00           O+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4                                                       
CONECT    4    3    5    6                                                  
CONECT    5    4                                                            
CONECT    6    4    7   29                                                  
CONECT    7    6    8    9                                                  
CONECT    8    7                                                            
CONECT    9    7   10   11                                                  
CONECT   10    9                                                            
CONECT   11    9   12   13                                                  
CONECT   12   11                                                            
CONECT   13   11   14   29                                                  
CONECT   14   13   15                                                       
CONECT   15   14   16   23                                                  
CONECT   16   15   17   18                                                  
CONECT   17   16                                                            
CONECT   18   16   19   20   21                                             
CONECT   19   18                                                            
CONECT   20   18                                                            
CONECT   21   18   22   28                                                  
CONECT   22   21   23   25                                                  
CONECT   23   22   15   24                                                  
CONECT   24   23                                                            
CONECT   25   22   26   27                                                  
CONECT   26   25                                                            
CONECT   27   25                                                            
CONECT   28   21                                                            
CONECT   29   13    6   30                                                  
CONECT   30   29                                                            
MASTER        0    0    0    0    0    0    0    0   30    0   62    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₂₂H₂₈O₈

Average Mass

420.4580 Da

Monoisotopic Mass

420.17842 Da

IUPAC Name

1-{3-[(5-acetyl-2,4,6-trihydroxy-3,3-dimethylcyclohexa-1,4-dien-1-yl)methyl]-2,4,6-trihydroxy-5-methylphenyl}butan-1-one

Traditional Name

1-{3-[(5-acetyl-2,4,6-trihydroxy-3,3-dimethylcyclohexa-1,4-dien-1-yl)methyl]-2,4,6-trihydroxy-5-methylphenyl}butan-1-one

CAS Registry Number

Not Available

SMILES

CCCC(=O)C1=C(O)C(C)=C(O)C(CC2=C(O)C(C)(C)C(O)=C(C2O)C(C)=O)=C1O

InChI Identifier

InChI=1S/C22H28O8/c1-6-7-13(24)15-17(26)9(2)16(25)11(18(15)27)8-12-19(28)14(10(3)23)21(30)22(4,5)20(12)29/h19,25-30H,6-8H2,1-5H3

InChI Key

QBTDHAKBGQYTFR-UHFFFAOYSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Dryopteris sieboldii	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as alkyl-phenylketones. These are aromatic compounds containing a ketone substituted by one alkyl group, and a phenyl group.

Kingdom

Organic compounds

Super Class

Organic oxygen compounds

Class

Organooxygen compounds

Sub Class

Carbonyl compounds

Direct Parent

Alkyl-phenylketones

Alternative Parents

Substituents

Alkyl-phenylketone
Acylphloroglucinol derivative
Butyrophenone
Benzenetriol
Phloroglucinol derivative
Benzoyl
Aryl alkyl ketone
O-cresol
P-cresol
Toluene
Phenol
Benzenoid
Monocyclic benzene moiety
Cyclitol or derivatives
Vinylogous acid
Secondary alcohol
Enol
Polyol
Organic oxide
Hydrocarbon derivative
Alcohol
Aromatic homomonocyclic compound

Molecular Framework

Aromatic homomonocyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	1.94	ALOGPS
logP	3.31	ChemAxon
logS	-3.1	ALOGPS
pKa (Strongest Acidic)	7.45	ChemAxon
pKa (Strongest Basic)	-3.4	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	8	ChemAxon
Hydrogen Donor Count	6	ChemAxon
Polar Surface Area	155.52 Å²	ChemAxon
Rotatable Bond Count	6	ChemAxon
Refractivity	113.15 m³·mol⁻¹	ChemAxon
Polarizability	43.26 Å³	ChemAxon
Number of Rings	2	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

Not Available

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for 1-{3-[(5-acetyl-2,4,6-trihydroxy-3,3-dimethylcyclohexa-1,4-dien-1-yl)methyl]-2,4,6-trihydroxy-5-methylphenyl}butan-1-one (NP0271815)

MOL for NP0271815 (1-{3-[(5-acetyl-2,4,6-trihydroxy-3,3-dimethylcyclohexa-1,4-dien-1-yl)methyl]-2,4,6-trihydroxy-5-methylphenyl}butan-1-one)

3D MOL for NP0271815 (1-{3-[(5-acetyl-2,4,6-trihydroxy-3,3-dimethylcyclohexa-1,4-dien-1-yl)methyl]-2,4,6-trihydroxy-5-methylphenyl}butan-1-one)

3D SDF for NP0271815 (1-{3-[(5-acetyl-2,4,6-trihydroxy-3,3-dimethylcyclohexa-1,4-dien-1-yl)methyl]-2,4,6-trihydroxy-5-methylphenyl}butan-1-one)

3D-SDF for NP0271815 (1-{3-[(5-acetyl-2,4,6-trihydroxy-3,3-dimethylcyclohexa-1,4-dien-1-yl)methyl]-2,4,6-trihydroxy-5-methylphenyl}butan-1-one)

PDB for NP0271815 (1-{3-[(5-acetyl-2,4,6-trihydroxy-3,3-dimethylcyclohexa-1,4-dien-1-yl)methyl]-2,4,6-trihydroxy-5-methylphenyl}butan-1-one)

3D PDB for NP0271815 (1-{3-[(5-acetyl-2,4,6-trihydroxy-3,3-dimethylcyclohexa-1,4-dien-1-yl)methyl]-2,4,6-trihydroxy-5-methylphenyl}butan-1-one)

SMILES for NP0271815 (1-{3-[(5-acetyl-2,4,6-trihydroxy-3,3-dimethylcyclohexa-1,4-dien-1-yl)methyl]-2,4,6-trihydroxy-5-methylphenyl}butan-1-one)

INCHI for NP0271815 (1-{3-[(5-acetyl-2,4,6-trihydroxy-3,3-dimethylcyclohexa-1,4-dien-1-yl)methyl]-2,4,6-trihydroxy-5-methylphenyl}butan-1-one)

Structure for NP0271815 (1-{3-[(5-acetyl-2,4,6-trihydroxy-3,3-dimethylcyclohexa-1,4-dien-1-yl)methyl]-2,4,6-trihydroxy-5-methylphenyl}butan-1-one)

3D Structure for NP0271815 (1-{3-[(5-acetyl-2,4,6-trihydroxy-3,3-dimethylcyclohexa-1,4-dien-1-yl)methyl]-2,4,6-trihydroxy-5-methylphenyl}butan-1-one)