NP-MRD: Showing NP-Card for 6-(acetyloxy)-1,3,4,5-tetramethoxyhexan-2-yl acetate (NP0267507)

Jump To Section:

Identification Spectra BioTaxonomy ChemoTaxonomy Physical properties Links References XML

Record Information

Version

2.0

Created at

2022-09-08 12:18:37 UTC

Updated at

2022-09-08 12:18:37 UTC

NP-MRD ID

NP0267507

Secondary Accession Numbers

None

Natural Product Identification

Common Name

6-(acetyloxy)-1,3,4,5-tetramethoxyhexan-2-yl acetate

Description

1,5-DI-O-ACETYL-2,3,4,6-TETRA-O-METHYLHEXITOL (1-D) belongs to the class of organic compounds known as dicarboxylic acids and derivatives. These are organic compounds containing exactly two carboxylic acid groups. 6-(acetyloxy)-1,3,4,5-tetramethoxyhexan-2-yl acetate is found in Grifola frondosa and Omphalotus japonicus. 1,5-DI-O-ACETYL-2,3,4,6-TETRA-O-METHYLHEXITOL (1-D) is an extremely weak basic (essentially neutral) compound (based on its pKa).

Structure

MOL 3D MOL SDF PDB SMILES InChI

     RDKit          3D

 48 47  0  0  0  0  0  0  0  0999 V2000
   -4.2327    1.7693   -1.3765 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5034    2.4125   -0.4322 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2257    2.0393   -0.2041 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0395    0.6978    0.3492 C   0  0  1  0  0  0  0  0  0  0  0  0
   -2.4848   -0.3987   -0.3750 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2941   -1.4103    0.2026 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7564   -2.5745   -0.5992 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5864   -1.2577    1.4113 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5253    0.4602    0.6935 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.1647    1.5278    1.4488 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1426    1.1941    2.8207 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.2639    0.2080   -0.4982 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.2576   -0.9124   -1.2212 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4373   -0.5867   -2.5594 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7171   -0.1488   -0.1408 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.4764    1.0636    0.3275 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.8518    0.7909    0.5327 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.2279   -0.1248    1.4900 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7000   -0.3537    1.6398 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4188   -0.7527    2.2156 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.3447   -0.5440   -1.3636 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.7992   -1.8488   -1.2557 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.2535    2.2405   -1.4197 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.2895    0.7004   -1.2500 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7482    1.9390   -2.3820 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6115    2.2375   -1.1309 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8013    2.8416    0.5033 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4888    0.6552    1.3706 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3274   -2.2305   -1.5012 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8696   -3.1777   -0.8873 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4789   -3.1232    0.0230 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6173   -0.4783    1.3181 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1605    0.8643    3.1118 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.5441    0.3342    2.9783 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.1659    2.0990    3.3655 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.3031    1.0295   -1.2084 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.5246   -0.3005   -3.0466 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1975    0.1909   -2.6404 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8059   -1.4888   -3.0815 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.8152   -0.9622    0.5559 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.3357    1.9255   -0.3707 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.0804    1.3869    1.2976 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.1788    0.6562    1.5809 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.9564   -0.8247    2.6004 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.0599   -0.9968    0.8042 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.5307   -2.0407   -0.4775 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.1128   -2.2592   -2.2362 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.8932   -2.4686   -0.9832 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  1  0
  4  5  1  0
  5  6  1  0
  6  7  1  0
  6  8  2  0
  4  9  1  0
  9 10  1  0
 10 11  1  0
  9 12  1  0
 12 13  1  0
 13 14  1  0
 12 15  1  0
 15 16  1  0
 16 17  1  0
 17 18  1  0
 18 19  1  0
 18 20  2  0
 15 21  1  0
 21 22  1  0
  1 23  1  0
  1 24  1  0
  1 25  1  0
  3 26  1  0
  3 27  1  0
  4 28  1  1
  7 29  1  0
  7 30  1  0
  7 31  1  0
  9 32  1  1
 11 33  1  0
 11 34  1  0
 11 35  1  0
 12 36  1  6
 14 37  1  0
 14 38  1  0
 14 39  1  0
 15 40  1  1
 16 41  1  0
 16 42  1  0
 19 43  1  0
 19 44  1  0
 19 45  1  0
 22 46  1  0
 22 47  1  0
 22 48  1  0
M  END


  Mrv1533004161519542D          

 22 21  0  0  0  0            999 V2000
    0.3146    5.3524    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8547    4.7288    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.6649    4.8847    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2050    4.2611    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9349    3.4815    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.4750    2.8579    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2050    2.0783    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.2221    2.5078    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.0151    4.4170    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2851    5.1965    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.7450    5.8202    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5552    3.7933    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2851    3.0138    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.8252    2.3902    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3653    3.9493    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.9054    3.3256    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7155    3.4815    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.2556    2.8579    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.0658    3.0138    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.9856    2.0783    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.6354    4.7288    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.4455    4.8847    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  1  0  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  6  7  2  0  0  0  0
  6  8  1  0  0  0  0
  4  9  1  0  0  0  0
  9 10  1  0  0  0  0
 10 11  1  0  0  0  0
  9 12  1  0  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 12 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  1  0  0  0  0
 18 19  2  0  0  0  0
 18 20  1  0  0  0  0
 15 21  1  0  0  0  0
 21 22  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0267507

> <DATABASE_NAME>
NP-MRD

> <SMILES>
COCC(OC(C)=O)C(OC)C(OC)C(COC(C)=O)OC

> <INCHI_IDENTIFIER>
InChI=1S/C14H26O8/c1-9(15)21-8-11(18-4)13(19-5)14(20-6)12(7-17-3)22-10(2)16/h11-14H,7-8H2,1-6H3

> <INCHI_KEY>
OVCJDQPBVXUBBF-UHFFFAOYSA-N

> <FORMULA>
C14H26O8

> <MOLECULAR_WEIGHT>
322.354

> <EXACT_MASS>
322.162767797

> <JCHEM_ACCEPTOR_COUNT>
6

> <JCHEM_ATOM_COUNT>
48

> <JCHEM_AVERAGE_POLARIZABILITY>
32.89874909752371

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
0

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
6-(acetyloxy)-1,3,4,5-tetramethoxyhexan-2-yl acetate

> <ALOGPS_LOGP>
0.81

> <JCHEM_LOGP>
-0.2752620133333327

> <ALOGPS_LOGS>
-1.73

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
0

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA_STRONGEST_BASIC>
-3.5469394849426803

> <JCHEM_POLAR_SURFACE_AREA>
89.52000000000002

> <JCHEM_REFRACTIVITY>
75.71140000000003

> <JCHEM_ROTATABLE_BOND_COUNT>
13

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
5.97e+00 g/l

> <JCHEM_TRADITIONAL_IUPAC>
6-(acetyloxy)-1,3,4,5-tetramethoxyhexan-2-yl acetate

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 16-APR-15   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   16-APR-15         0                                  
HETATM    1  C   UNK     0       0.587   9.991   0.000  0.00  0.00           C+0
HETATM    2  O   UNK     0       1.596   8.827   0.000  0.00  0.00           O+0
HETATM    3  C   UNK     0       3.108   9.118   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       4.116   7.954   0.000  0.00  0.00           C+0
HETATM    5  O   UNK     0       3.612   6.499   0.000  0.00  0.00           O+0
HETATM    6  C   UNK     0       4.620   5.335   0.000  0.00  0.00           C+0
HETATM    7  O   UNK     0       4.116   3.880   0.000  0.00  0.00           O+0
HETATM    8  C   UNK     0       6.015   4.681   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       5.628   8.245   0.000  0.00  0.00           C+0
HETATM   10  O   UNK     0       6.132   9.700   0.000  0.00  0.00           O+0
HETATM   11  C   UNK     0       5.124  10.864   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       6.636   7.081   0.000  0.00  0.00           C+0
HETATM   13  O   UNK     0       6.132   5.626   0.000  0.00  0.00           O+0
HETATM   14  C   UNK     0       7.140   4.462   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       8.149   7.372   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       9.157   6.208   0.000  0.00  0.00           C+0
HETATM   17  O   UNK     0      10.669   6.499   0.000  0.00  0.00           O+0
HETATM   18  C   UNK     0      11.677   5.335   0.000  0.00  0.00           C+0
HETATM   19  O   UNK     0      13.189   5.626   0.000  0.00  0.00           O+0
HETATM   20  C   UNK     0      11.173   3.880   0.000  0.00  0.00           C+0
HETATM   21  O   UNK     0       8.653   8.827   0.000  0.00  0.00           O+0
HETATM   22  C   UNK     0      10.165   9.118   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4                                                       
CONECT    4    3    5    9                                                  
CONECT    5    4    6                                                       
CONECT    6    5    7    8                                                  
CONECT    7    6                                                            
CONECT    8    6                                                            
CONECT    9    4   10   12                                                  
CONECT   10    9   11                                                       
CONECT   11   10                                                            
CONECT   12    9   13   15                                                  
CONECT   13   12   14                                                       
CONECT   14   13                                                            
CONECT   15   12   16   21                                                  
CONECT   16   15   17                                                       
CONECT   17   16   18                                                       
CONECT   18   17   19   20                                                  
CONECT   19   18                                                            
CONECT   20   18                                                            
CONECT   21   15   22                                                       
CONECT   22   21                                                            
MASTER        0    0    0    0    0    0    0    0   22    0   42    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₁₄H₂₆O₈

Average Mass

322.3540 Da

Monoisotopic Mass

322.16277 Da

IUPAC Name

6-(acetyloxy)-1,3,4,5-tetramethoxyhexan-2-yl acetate

Traditional Name

6-(acetyloxy)-1,3,4,5-tetramethoxyhexan-2-yl acetate

CAS Registry Number

Not Available

SMILES

COCC(OC(C)=O)C(OC)C(OC)C(COC(C)=O)OC

InChI Identifier

InChI=1S/C14H26O8/c1-9(15)21-8-11(18-4)13(19-5)14(20-6)12(7-17-3)22-10(2)16/h11-14H,7-8H2,1-6H3

InChI Key

OVCJDQPBVXUBBF-UHFFFAOYSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Grifola frondosa	LOTUS Database	35616633
Lampteromyces japonicus	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as dicarboxylic acids and derivatives. These are organic compounds containing exactly two carboxylic acid groups.

Kingdom

Organic compounds

Super Class

Organic acids and derivatives

Class

Carboxylic acids and derivatives

Sub Class

Dicarboxylic acids and derivatives

Direct Parent

Dicarboxylic acids and derivatives

Alternative Parents

Substituents

Monosaccharide
Dicarboxylic acid or derivatives
Carboxylic acid ester
Ether
Dialkyl ether
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Carbonyl group
Aliphatic acyclic compound

Molecular Framework

Aliphatic acyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	0.81	ALOGPS
logP	-0.28	ChemAxon
logS	-1.7	ALOGPS
pKa (Strongest Basic)	-3.5	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	6	ChemAxon
Hydrogen Donor Count	0	ChemAxon
Polar Surface Area	89.52 Å²	ChemAxon
Rotatable Bond Count	13	ChemAxon
Refractivity	75.71 m³·mol⁻¹	ChemAxon
Polarizability	32.9 Å³	ChemAxon
Number of Rings	0	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

538739

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for 6-(acetyloxy)-1,3,4,5-tetramethoxyhexan-2-yl acetate (NP0267507)

MOL for NP0267507 (6-(acetyloxy)-1,3,4,5-tetramethoxyhexan-2-yl acetate)

3D MOL for NP0267507 (6-(acetyloxy)-1,3,4,5-tetramethoxyhexan-2-yl acetate)

3D SDF for NP0267507 (6-(acetyloxy)-1,3,4,5-tetramethoxyhexan-2-yl acetate)

3D-SDF for NP0267507 (6-(acetyloxy)-1,3,4,5-tetramethoxyhexan-2-yl acetate)

PDB for NP0267507 (6-(acetyloxy)-1,3,4,5-tetramethoxyhexan-2-yl acetate)

3D PDB for NP0267507 (6-(acetyloxy)-1,3,4,5-tetramethoxyhexan-2-yl acetate)

SMILES for NP0267507 (6-(acetyloxy)-1,3,4,5-tetramethoxyhexan-2-yl acetate)

INCHI for NP0267507 (6-(acetyloxy)-1,3,4,5-tetramethoxyhexan-2-yl acetate)

Structure for NP0267507 (6-(acetyloxy)-1,3,4,5-tetramethoxyhexan-2-yl acetate)

3D Structure for NP0267507 (6-(acetyloxy)-1,3,4,5-tetramethoxyhexan-2-yl acetate)