NP-MRD: Showing NP-Card for (2r,3r,4s)-2-[(1s,3r,6s,8r,11r,12s,15r,16r)-6-hydroxy-7,7,12,16-tetramethylpentacyclo[9.7.0.0¹,³.0³,⁸.0¹²,¹⁶]octadecan-15-yl]-6-methyl-5-methylidenehept-6-ene-1,3,4-triol (NP0259838)

Jump To Section:

Identification Spectra BioTaxonomy ChemoTaxonomy Physical properties Links References XML

Record Information

Version

2.0

Created at

2022-09-08 01:50:22 UTC

Updated at

2022-09-08 01:50:23 UTC

NP-MRD ID

NP0259838

Secondary Accession Numbers

None

Natural Product Identification

Common Name

(2r,3r,4s)-2-[(1s,3r,6s,8r,11r,12s,15r,16r)-6-hydroxy-7,7,12,16-tetramethylpentacyclo[9.7.0.0¹,³.0³,⁸.0¹²,¹⁶]octadecan-15-yl]-6-methyl-5-methylidenehept-6-ene-1,3,4-triol

Description

(2R,3R,4S)-2-[(1S,3R,6S,8R,11R,12S,15R,16R)-6-hydroxy-7,7,12,16-tetramethylpentacyclo[9.7.0.0¹,³.0³,⁸.0¹²,¹⁶]Octadecan-15-yl]-6-methyl-5-methylidenehept-6-ene-1,3,4-triol belongs to the class of organic compounds known as cycloartanols and derivatives. These are steroids containing a cycloartanol moiety. (2r,3r,4s)-2-[(1s,3r,6s,8r,11r,12s,15r,16r)-6-hydroxy-7,7,12,16-tetramethylpentacyclo[9.7.0.0¹,³.0³,⁸.0¹²,¹⁶]octadecan-15-yl]-6-methyl-5-methylidenehept-6-ene-1,3,4-triol is found in Guarea guidonia. Based on a literature review very few articles have been published on (2R,3R,4S)-2-[(1S,3R,6S,8R,11R,12S,15R,16R)-6-hydroxy-7,7,12,16-tetramethylpentacyclo[9.7.0.0¹,³.0³,⁸.0¹²,¹⁶]Octadecan-15-yl]-6-methyl-5-methylidenehept-6-ene-1,3,4-triol.

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652309082203502D          

 35 39  0  0  1  0            999 V2000
    0.6141   -5.9669    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4391   -5.9669    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8516   -6.6813    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8516   -5.2524    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4391   -4.5379    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6766   -5.2524    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.0891   -5.9669    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.0891   -4.5379    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.6766   -3.8235    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.9141   -4.5379    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.3266   -5.2524    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9141   -5.9669    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.3266   -3.8235    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.9910   -3.0698    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.6041   -2.5178    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.3186   -2.9303    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    5.4048   -2.1098    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.1032   -2.6753    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    6.2748   -1.8683    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.0594   -1.6134    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.6725   -2.1654    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    8.4571   -1.9105    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.0698   -1.1821    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.1072   -1.4026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.0702   -2.4625    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    9.8548   -2.2076    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.8987   -3.2695    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.1140   -3.5244    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.5009   -2.9724    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    7.3294   -3.7794    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.7163   -3.2273    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    6.5448   -4.0343    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7602   -4.2893    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.1471   -3.7372    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.8921   -4.5218    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0  0  0  0
  2  3  1  0  0  0  0
  2  4  1  0  0  0  0
  4  5  2  0  0  0  0
  4  6  1  0  0  0  0
  6  7  1  1  0  0  0
  6  8  1  0  0  0  0
  8  9  1  6  0  0  0
  8 10  1  0  0  0  0
 10 11  1  6  0  0  0
 11 12  1  0  0  0  0
 13 10  1  1  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  6  0  0  0
 16 18  1  0  0  0  0
 18 19  1  1  0  0  0
 19 20  1  0  0  0  0
 21 20  1  1  0  0  0
 21 22  1  0  0  0  0
 22 23  1  0  0  0  0
 22 24  1  0  0  0  0
 22 25  1  0  0  0  0
 25 26  1  1  0  0  0
 25 27  1  0  0  0  0
 27 28  1  0  0  0  0
 28 29  1  0  0  0  0
 21 29  1  0  0  0  0
 29 30  1  1  0  0  0
 31 30  1  1  0  0  0
 18 31  1  0  0  0  0
 29 31  1  0  0  0  0
 31 32  1  0  0  0  0
 32 33  1  0  0  0  0
 33 34  1  0  0  0  0
 13 34  1  0  0  0  0
 16 34  1  0  0  0  0
 34 35  1  1  0  0  0
M  END

     RDKit          3D

 85 89  0  0  0  0  0  0  0  0999 V2000
    3.5614    3.2631   -3.1599 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.6145    3.6136   -2.4378 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.8398    4.0537   -3.2053 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7206    3.5921   -1.0048 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.8263    3.9970   -0.4193 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6663    3.0637   -0.0631 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.8026    3.7707    1.0963 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.7030    1.5939    0.0001 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.5346    1.0080   -1.2480 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.1575    0.8710    1.1496 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.9263    1.2655    2.4291 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2848    0.9882    2.3214 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.7459    0.8214    1.4895 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.9894    2.0666    1.7703 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4956    1.7342    1.5179 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4592    0.2293    1.4901 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.2094   -0.2015    2.8966 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6274   -0.4561    0.8869 C   0  0  1  0  0  0  0  0  0  0  0  0
   -2.8117    0.4031    0.6033 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9784   -0.4422    0.1578 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7329   -1.9120    0.3449 C   0  0  1  0  0  0  0  0  0  0  0  0
   -4.9130   -2.6833   -0.2091 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3094   -3.8137    0.7479 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1537   -1.8408   -0.3704 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6023   -3.3358   -1.5314 C   0  0  1  0  0  0  0  0  0  0  0  0
   -4.4809   -2.3885   -2.5614 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4332   -4.2710   -1.4779 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3521   -3.7722   -0.5291 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5109   -2.2869   -0.4289 C   0  0  1  0  0  0  0  0  0  0  0  0
   -2.0176   -1.4576   -1.5188 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3161   -1.4061   -0.2272 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.0339   -2.1604   -0.0081 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1366   -1.3722    0.4279 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7919    0.0628    0.6016 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.5960    0.7149   -0.7180 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6010    3.2970   -4.2572 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.6419    2.9634   -2.7156 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.6448    3.3137   -2.9753 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.6386    4.0491   -4.2973 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.0984    5.0745   -2.8835 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.6403    4.3444   -1.0663 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.9917    4.0013    0.6563 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.7031    3.3566   -0.6086 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.8382    4.7341    0.8501 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.8737    1.3874    0.1385 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.0306    0.1474   -1.3208 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.4994   -0.2155    1.0056 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.5707    0.5540    3.2540 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.7917    2.2844    2.7414 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.4503    0.0268    2.3459 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.7217    0.2582    2.5145 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.1904    2.9290    1.1396 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.0202    2.3409    2.8681 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1466    2.0365    2.3454 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8693    2.1917    0.6023 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.3606   -1.1134    3.0405 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.1059    0.6381    3.5849 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2408   -0.4523    3.3130 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0045   -1.1598    1.7172 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6822    1.2235   -0.0882 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1089    0.8551    1.5997 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9078   -0.1772    0.7301 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1832   -0.2626   -0.9157 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6811   -2.1945    1.4344 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.5617   -4.7512    0.2084 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.2319   -3.5474    1.3287 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5334   -3.9938    1.5130 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.9308   -2.5142   -0.7862 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.5058   -1.5592    0.6473 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.0685   -0.9793   -1.0239 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.5067   -3.9410   -1.8041 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3543   -1.9365   -2.6813 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9575   -4.2387   -2.5036 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7068   -5.3209   -1.2667 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3308   -4.0032   -0.9239 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4017   -4.2763    0.4595 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4525   -1.9840   -2.3418 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4338   -0.5113   -1.8711 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.2201   -2.6527   -0.9830 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2686   -3.0263    0.6754 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.9871   -1.4305   -0.2997 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.5383   -1.8486    1.3527 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.9980    1.7384   -0.8015 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.9640    0.1612   -1.6019 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5111    0.8709   -0.9245 H   0  0  0  0  0  0  0  0  0  0  0  0
  3  2  1  0
  2  1  2  3
  2  4  1  0
  4  5  2  3
  4  6  1  0
  6  7  1  0
  6  8  1  0
  8  9  1  0
  8 10  1  0
 10 11  1  0
 11 12  1  0
 10 13  1  0
 13 14  1  0
 14 15  1  0
 15 16  1  0
 16 17  1  1
 16 18  1  0
 18 19  1  0
 19 20  1  0
 20 21  1  0
 21 29  1  0
 29 30  1  6
 31 30  1  6
 31 32  1  0
 32 33  1  0
 33 34  1  0
 34 35  1  6
 29 28  1  0
 28 27  1  0
 27 25  1  0
 25 26  1  0
 25 22  1  0
 22 23  1  0
 22 24  1  0
 34 13  1  0
 34 16  1  0
 31 18  1  0
 22 21  1  0
 31 29  1  0
  3 38  1  0
  3 39  1  0
  3 40  1  0
  1 36  1  0
  1 37  1  0
  5 41  1  0
  5 42  1  0
  6 43  1  6
  7 44  1  0
  8 45  1  1
  9 46  1  0
 10 47  1  6
 11 48  1  0
 11 49  1  0
 12 50  1  0
 13 51  1  1
 14 52  1  0
 14 53  1  0
 15 54  1  0
 15 55  1  0
 17 56  1  0
 17 57  1  0
 17 58  1  0
 18 59  1  1
 19 60  1  0
 19 61  1  0
 20 62  1  0
 20 63  1  0
 21 64  1  1
 30 77  1  0
 30 78  1  0
 32 79  1  0
 32 80  1  0
 33 81  1  0
 33 82  1  0
 35 83  1  0
 35 84  1  0
 35 85  1  0
 28 75  1  0
 28 76  1  0
 27 73  1  0
 27 74  1  0
 25 71  1  6
 26 72  1  0
 23 65  1  0
 23 66  1  0
 23 67  1  0
 24 68  1  0
 24 69  1  0
 24 70  1  0
M  END


  Mrv1652309082203502D          

 35 39  0  0  1  0            999 V2000
    0.6141   -5.9669    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4391   -5.9669    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8516   -6.6813    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8516   -5.2524    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4391   -4.5379    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6766   -5.2524    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.0891   -5.9669    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.0891   -4.5379    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.6766   -3.8235    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.9141   -4.5379    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.3266   -5.2524    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9141   -5.9669    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.3266   -3.8235    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.9910   -3.0698    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.6041   -2.5178    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.3186   -2.9303    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    5.4048   -2.1098    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.1032   -2.6753    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    6.2748   -1.8683    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.0594   -1.6134    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.6725   -2.1654    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    8.4571   -1.9105    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.0698   -1.1821    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.1072   -1.4026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.0702   -2.4625    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    9.8548   -2.2076    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.8987   -3.2695    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.1140   -3.5244    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.5009   -2.9724    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    7.3294   -3.7794    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.7163   -3.2273    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    6.5448   -4.0343    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7602   -4.2893    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.1471   -3.7372    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.8921   -4.5218    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0  0  0  0
  2  3  1  0  0  0  0
  2  4  1  0  0  0  0
  4  5  2  0  0  0  0
  4  6  1  0  0  0  0
  6  7  1  1  0  0  0
  6  8  1  0  0  0  0
  8  9  1  6  0  0  0
  8 10  1  0  0  0  0
 10 11  1  6  0  0  0
 11 12  1  0  0  0  0
 13 10  1  1  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  6  0  0  0
 16 18  1  0  0  0  0
 18 19  1  1  0  0  0
 19 20  1  0  0  0  0
 21 20  1  1  0  0  0
 21 22  1  0  0  0  0
 22 23  1  0  0  0  0
 22 24  1  0  0  0  0
 22 25  1  0  0  0  0
 25 26  1  1  0  0  0
 25 27  1  0  0  0  0
 27 28  1  0  0  0  0
 28 29  1  0  0  0  0
 21 29  1  0  0  0  0
 29 30  1  1  0  0  0
 31 30  1  1  0  0  0
 18 31  1  0  0  0  0
 29 31  1  0  0  0  0
 31 32  1  0  0  0  0
 32 33  1  0  0  0  0
 33 34  1  0  0  0  0
 13 34  1  0  0  0  0
 16 34  1  0  0  0  0
 34 35  1  1  0  0  0
M  END
> <DATABASE_ID>
NP0259838

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CC(=C)C(=C)[C@H](O)[C@H](O)[C@@H](CO)[C@H]1CC[C@@]2(C)[C@H]3CC[C@@H]4[C@]5(C[C@@]35CC[C@]12C)CC[C@H](O)C4(C)C

> <INCHI_IDENTIFIER>
InChI=1S/C31H50O4/c1-18(2)19(3)25(34)26(35)20(16-32)21-10-12-29(7)23-9-8-22-27(4,5)24(33)11-13-30(22)17-31(23,30)15-14-28(21,29)6/h20-26,32-35H,1,3,8-17H2,2,4-7H3/t20-,21+,22-,23+,24-,25-,26+,28+,29-,30+,31-/m0/s1

> <INCHI_KEY>
BPOCTWJJJPPYFY-VCKCDYDKSA-N

> <FORMULA>
C31H50O4

> <MOLECULAR_WEIGHT>
486.737

> <EXACT_MASS>
486.37091009

> <JCHEM_ACCEPTOR_COUNT>
4

> <JCHEM_ATOM_COUNT>
85

> <JCHEM_AVERAGE_POLARIZABILITY>
58.24514128126953

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
4

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(2R,3R,4S)-2-[(1S,3R,6S,8R,11R,12S,15R,16R)-6-hydroxy-7,7,12,16-tetramethylpentacyclo[9.7.0.0^{1,3}.0^{3,8}.0^{12,16}]octadecan-15-yl]-6-methyl-5-methylidenehept-6-ene-1,3,4-triol

> <JCHEM_LOGP>
3.922086501333334

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
5

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
14.732354282028343

> <JCHEM_PKA_STRONGEST_ACIDIC>
13.367250051336747

> <JCHEM_PKA_STRONGEST_BASIC>
-0.8351325136321294

> <JCHEM_POLAR_SURFACE_AREA>
80.92

> <JCHEM_REFRACTIVITY>
139.91669999999996

> <JCHEM_ROTATABLE_BOND_COUNT>
6

> <JCHEM_RULE_OF_FIVE>
1

> <JCHEM_TRADITIONAL_IUPAC>
(2R,3R,4S)-2-[(1S,3R,6S,8R,11R,12S,15R,16R)-6-hydroxy-7,7,12,16-tetramethylpentacyclo[9.7.0.0^{1,3}.0^{3,8}.0^{12,16}]octadecan-15-yl]-6-methyl-5-methylidenehept-6-ene-1,3,4-triol

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 08-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   08-SEP-22         0                                  
HETATM    1  C   UNK     0       1.146 -11.138   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       2.686 -11.138   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       3.456 -12.472   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       3.456  -9.804   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       2.686  -8.471   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       4.996  -9.804   0.000  0.00  0.00           C+0
HETATM    7  O   UNK     0       5.766 -11.138   0.000  0.00  0.00           O+0
HETATM    8  C   UNK     0       5.766  -8.471   0.000  0.00  0.00           C+0
HETATM    9  O   UNK     0       4.996  -7.137   0.000  0.00  0.00           O+0
HETATM   10  C   UNK     0       7.306  -8.471   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       8.076  -9.804   0.000  0.00  0.00           C+0
HETATM   12  O   UNK     0       7.306 -11.138   0.000  0.00  0.00           O+0
HETATM   13  C   UNK     0       8.076  -7.137   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       7.450  -5.730   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       8.594  -4.700   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       9.928  -5.470   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0      10.089  -3.938   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0      11.393  -4.994   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0      11.713  -3.488   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0      13.178  -3.012   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0      14.322  -4.042   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0      15.787  -3.566   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0      15.064  -2.207   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0      17.000  -2.618   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0      16.931  -4.597   0.000  0.00  0.00           C+0
HETATM   26  O   UNK     0      18.396  -4.121   0.000  0.00  0.00           O+0
HETATM   27  C   UNK     0      16.611  -6.103   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0      15.146  -6.579   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0      14.002  -5.548   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0      13.682  -7.055   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0      12.537  -6.024   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0      12.217  -7.531   0.000  0.00  0.00           C+0
HETATM   33  C   UNK     0      10.752  -8.007   0.000  0.00  0.00           C+0
HETATM   34  C   UNK     0       9.608  -6.976   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0       9.132  -8.441   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3    4                                                  
CONECT    3    2                                                            
CONECT    4    2    5    6                                                  
CONECT    5    4                                                            
CONECT    6    4    7    8                                                  
CONECT    7    6                                                            
CONECT    8    6    9   10                                                  
CONECT    9    8                                                            
CONECT   10    8   11   13                                                  
CONECT   11   10   12                                                       
CONECT   12   11                                                            
CONECT   13   10   14   34                                                  
CONECT   14   13   15                                                       
CONECT   15   14   16                                                       
CONECT   16   15   17   18   34                                             
CONECT   17   16                                                            
CONECT   18   16   19   31                                                  
CONECT   19   18   20                                                       
CONECT   20   19   21                                                       
CONECT   21   20   22   29                                                  
CONECT   22   21   23   24   25                                             
CONECT   23   22                                                            
CONECT   24   22                                                            
CONECT   25   22   26   27                                                  
CONECT   26   25                                                            
CONECT   27   25   28                                                       
CONECT   28   27   29                                                       
CONECT   29   28   21   30   31                                             
CONECT   30   29   31                                                       
CONECT   31   30   18   29   32                                             
CONECT   32   31   33                                                       
CONECT   33   32   34                                                       
CONECT   34   33   13   16   35                                             
CONECT   35   34                                                            
MASTER        0    0    0    0    0    0    0    0   35    0   78    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₃₁H₅₀O₄

Average Mass

486.7370 Da

Monoisotopic Mass

486.37091 Da

IUPAC Name

(2R,3R,4S)-2-[(1S,3R,6S,8R,11R,12S,15R,16R)-6-hydroxy-7,7,12,16-tetramethylpentacyclo[9.7.0.0^{1,3}.0^{3,8}.0^{12,16}]octadecan-15-yl]-6-methyl-5-methylidenehept-6-ene-1,3,4-triol

Traditional Name

(2R,3R,4S)-2-[(1S,3R,6S,8R,11R,12S,15R,16R)-6-hydroxy-7,7,12,16-tetramethylpentacyclo[9.7.0.0^{1,3}.0^{3,8}.0^{12,16}]octadecan-15-yl]-6-methyl-5-methylidenehept-6-ene-1,3,4-triol

CAS Registry Number

Not Available

SMILES

CC(=C)C(=C)[C@H](O)[C@H](O)[C@@H](CO)[C@H]1CC[C@@]2(C)[C@H]3CC[C@@H]4[C@]5(C[C@@]35CC[C@]12C)CC[C@H](O)C4(C)C

InChI Identifier

InChI=1S/C31H50O4/c1-18(2)19(3)25(34)26(35)20(16-32)21-10-12-29(7)23-9-8-22-27(4,5)24(33)11-13-30(22)17-31(23,30)15-14-28(21,29)6/h20-26,32-35H,1,3,8-17H2,2,4-7H3/t20-,21+,22-,23+,24-,25-,26+,28+,29-,30+,31-/m0/s1

InChI Key

BPOCTWJJJPPYFY-VCKCDYDKSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Guarea guidonia	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as cycloartanols and derivatives. These are steroids containing a cycloartanol moiety.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Steroids and steroid derivatives

Sub Class

Cycloartanols and derivatives

Direct Parent

Cycloartanols and derivatives

Alternative Parents

Substituents

Cycloartanol-skeleton
9b,19-cyclo-lanostane-skeleton
Cycloartane-skeleton
Triterpenoid
Tetrahydroxy bile acid, alcohol, or derivatives
Hydroxy bile acid, alcohol, or derivatives
23-hydroxysteroid
Bile acid, alcohol, or derivatives
22-hydroxysteroid
21-hydroxysteroid
3-beta-hydroxysteroid
3-hydroxysteroid
Hydroxysteroid
Fatty alcohol
Fatty acyl
Cyclic alcohol
Secondary alcohol
Polyol
Primary alcohol
Hydrocarbon derivative
Organic oxygen compound
Alcohol
Organooxygen compound
Aliphatic homopolycyclic compound

Molecular Framework

Aliphatic homopolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	3.92	ChemAxon
pKa (Strongest Acidic)	13.37	ChemAxon
pKa (Strongest Basic)	-0.84	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	4	ChemAxon
Hydrogen Donor Count	4	ChemAxon
Polar Surface Area	80.92 Å²	ChemAxon
Rotatable Bond Count	6	ChemAxon
Refractivity	139.92 m³·mol⁻¹	ChemAxon
Polarizability	58.25 Å³	ChemAxon
Number of Rings	5	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	Yes	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

162855000

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for (2r,3r,4s)-2-[(1s,3r,6s,8r,11r,12s,15r,16r)-6-hydroxy-7,7,12,16-tetramethylpentacyclo[9.7.0.0¹,³.0³,⁸.0¹²,¹⁶]octadecan-15-yl]-6-methyl-5-methylidenehept-6-ene-1,3,4-triol (NP0259838)

MOL for NP0259838 ((2r,3r,4s)-2-[(1s,3r,6s,8r,11r,12s,15r,16r)-6-hydroxy-7,7,12,16-tetramethylpentacyclo[9.7.0.0¹,³.0³,⁸.0¹²,¹⁶]octadecan-15-yl]-6-methyl-5-methylidenehept-6-ene-1,3,4-triol)

3D MOL for NP0259838 ((2r,3r,4s)-2-[(1s,3r,6s,8r,11r,12s,15r,16r)-6-hydroxy-7,7,12,16-tetramethylpentacyclo[9.7.0.0¹,³.0³,⁸.0¹²,¹⁶]octadecan-15-yl]-6-methyl-5-methylidenehept-6-ene-1,3,4-triol)

3D SDF for NP0259838 ((2r,3r,4s)-2-[(1s,3r,6s,8r,11r,12s,15r,16r)-6-hydroxy-7,7,12,16-tetramethylpentacyclo[9.7.0.0¹,³.0³,⁸.0¹²,¹⁶]octadecan-15-yl]-6-methyl-5-methylidenehept-6-ene-1,3,4-triol)

3D-SDF for NP0259838 ((2r,3r,4s)-2-[(1s,3r,6s,8r,11r,12s,15r,16r)-6-hydroxy-7,7,12,16-tetramethylpentacyclo[9.7.0.0¹,³.0³,⁸.0¹²,¹⁶]octadecan-15-yl]-6-methyl-5-methylidenehept-6-ene-1,3,4-triol)

PDB for NP0259838 ((2r,3r,4s)-2-[(1s,3r,6s,8r,11r,12s,15r,16r)-6-hydroxy-7,7,12,16-tetramethylpentacyclo[9.7.0.0¹,³.0³,⁸.0¹²,¹⁶]octadecan-15-yl]-6-methyl-5-methylidenehept-6-ene-1,3,4-triol)

3D PDB for NP0259838 ((2r,3r,4s)-2-[(1s,3r,6s,8r,11r,12s,15r,16r)-6-hydroxy-7,7,12,16-tetramethylpentacyclo[9.7.0.0¹,³.0³,⁸.0¹²,¹⁶]octadecan-15-yl]-6-methyl-5-methylidenehept-6-ene-1,3,4-triol)

SMILES for NP0259838 ((2r,3r,4s)-2-[(1s,3r,6s,8r,11r,12s,15r,16r)-6-hydroxy-7,7,12,16-tetramethylpentacyclo[9.7.0.0¹,³.0³,⁸.0¹²,¹⁶]octadecan-15-yl]-6-methyl-5-methylidenehept-6-ene-1,3,4-triol)

INCHI for NP0259838 ((2r,3r,4s)-2-[(1s,3r,6s,8r,11r,12s,15r,16r)-6-hydroxy-7,7,12,16-tetramethylpentacyclo[9.7.0.0¹,³.0³,⁸.0¹²,¹⁶]octadecan-15-yl]-6-methyl-5-methylidenehept-6-ene-1,3,4-triol)

Structure for NP0259838 ((2r,3r,4s)-2-[(1s,3r,6s,8r,11r,12s,15r,16r)-6-hydroxy-7,7,12,16-tetramethylpentacyclo[9.7.0.0¹,³.0³,⁸.0¹²,¹⁶]octadecan-15-yl]-6-methyl-5-methylidenehept-6-ene-1,3,4-triol)

3D Structure for NP0259838 ((2r,3r,4s)-2-[(1s,3r,6s,8r,11r,12s,15r,16r)-6-hydroxy-7,7,12,16-tetramethylpentacyclo[9.7.0.0¹,³.0³,⁸.0¹²,¹⁶]octadecan-15-yl]-6-methyl-5-methylidenehept-6-ene-1,3,4-triol)