NP-MRD: Showing NP-Card for [(1s,3r,4r,5r)-1,3,4-trihydroxy-5-{[(2e)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy}cyclohexyl]acetic acid (NP0259495)

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Record Information

Version

2.0

Created at

2022-09-08 01:23:20 UTC

Updated at

2022-09-08 01:23:21 UTC

NP-MRD ID

NP0259495

Secondary Accession Numbers

None

Natural Product Identification

Common Name

[(1s,3r,4r,5r)-1,3,4-trihydroxy-5-{[(2e)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy}cyclohexyl]acetic acid

Description

(1S)-5alpha-[[3-(4-Hydroxyphenyl)-1-oxo-2-propenyl]oxy]-1beta,3beta,4beta-trihydroxycyclohexane-1-acetic acid belongs to the class of organic compounds known as coumaric acid esters. These are aromatic compounds containing an ester derivative of coumaric acid. [(1s,3r,4r,5r)-1,3,4-trihydroxy-5-{[(2e)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy}cyclohexyl]acetic acid is found in Onobrychis viciifolia. Based on a literature review very few articles have been published on (1S)-5alpha-[[3-(4-Hydroxyphenyl)-1-oxo-2-propenyl]oxy]-1beta,3beta,4beta-trihydroxycyclohexane-1-acetic acid.

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652309082203232D          

 25 26  0  0  1  0            999 V2000
    2.9218   -1.6733    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.3915   -2.3053    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5791   -2.1620    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.6737   -3.0805    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -3.7125    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.6131   -3.0805    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -4.1250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -4.9500    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.5724   -5.3625    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -5.3625    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.1434   -6.1875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -4.9500    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.7145   -5.3625    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -6.1875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -6.6000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -6.6000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -7.4250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -7.8375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -8.6625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289   -9.0750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1434   -8.6625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8579   -9.0750    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1434   -7.8375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289   -7.4250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -4.1250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0  0  0  0
  2  3  1  0  0  0  0
  2  4  1  0  0  0  0
  5  4  1  6  0  0  0
  5  6  1  1  0  0  0
  5  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  1  0  0  0
  8 10  1  0  0  0  0
 10 11  1  1  0  0  0
 10 12  1  0  0  0  0
 12 13  1  6  0  0  0
 13 14  1  0  0  0  0
 14 15  2  0  0  0  0
 14 16  1  0  0  0  0
 16 17  2  0  0  0  0
 17 18  1  0  0  0  0
 18 19  2  0  0  0  0
 19 20  1  0  0  0  0
 20 21  2  0  0  0  0
 21 22  1  0  0  0  0
 21 23  1  0  0  0  0
 23 24  2  0  0  0  0
 18 24  1  0  0  0  0
 12 25  1  0  0  0  0
  5 25  1  0  0  0  0
M  END

     RDKit          3D

 45 46  0  0  0  0  0  0  0  0999 V2000
   -4.4659    0.3865    2.0360 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9545    1.4780    1.6828 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1260    2.1155    2.5973 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1995    2.0732    0.3787 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8206    1.1890   -0.8080 C   0  0  2  0  0  0  0  0  0  0  0  0
   -4.3722    1.9112   -1.9145 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5585   -0.1041   -0.8123 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7572   -1.3358   -0.6003 C   0  0  1  0  0  0  0  0  0  0  0  0
   -3.5920   -2.0641   -1.8050 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4031   -1.1646   -0.0169 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.7294   -2.4006   -0.2086 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6374   -0.1182   -0.7614 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.4168    0.0891   -0.0391 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.8206   -0.2445   -0.5556 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8568   -0.7434   -1.6976 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.0568   -0.0325    0.1838 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1970   -0.3765   -0.3783 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.5118   -0.2283    0.2310 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.6533    0.2967    1.4781 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9335    0.4121    2.0124 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.0371    0.0027    1.2923 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.3017    0.1249    1.8390 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.8547   -0.5226    0.0354 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.6078   -0.6523   -0.5245 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3625    1.1414   -1.0235 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5372    1.6365    3.2732 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3059    2.3079    0.3381 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7063    3.0537    0.2387 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6834    2.3227   -2.4561 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3891   -0.0993   -0.0432 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1400   -0.2833   -1.7713 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3103   -2.0515    0.0614 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2682   -1.4783   -2.5372 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3492   -1.0064    1.0720 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3652   -2.4146   -1.1153 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3760   -0.5723   -1.7648 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.0608    0.3970    1.1790 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.1394   -0.8123   -1.3942 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.7864    0.6197    2.0483 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.0218    0.8297    3.0034 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.8165    0.9589    1.6897 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.7021   -0.8463   -0.5496 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.4748   -1.0661   -1.5114 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1030    1.5558   -2.0449 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9032    1.9191   -0.3368 H   0  0  0  0  0  0  0  0  0  0  0  0
  9  8  1  0
  8  7  1  0
  7  5  1  0
  5  6  1  6
  5  4  1  0
  4  2  1  0
  2  3  1  0
  2  1  2  0
  5 25  1  0
 25 12  1  0
 12 13  1  0
 13 14  1  0
 14 15  2  0
 14 16  1  0
 16 17  2  0
 17 18  1  0
 18 19  2  0
 19 20  1  0
 20 21  2  0
 21 22  1  0
 21 23  1  0
 23 24  2  0
 12 10  1  0
 10 11  1  0
 10  8  1  0
 24 18  1  0
  9 33  1  0
  8 32  1  1
  7 30  1  0
  7 31  1  0
  6 29  1  0
  4 27  1  0
  4 28  1  0
  3 26  1  0
 25 44  1  0
 25 45  1  0
 12 36  1  6
 16 37  1  0
 17 38  1  0
 19 39  1  0
 20 40  1  0
 22 41  1  0
 23 42  1  0
 24 43  1  0
 10 34  1  1
 11 35  1  0
M  END


  Mrv1652309082203232D          

 25 26  0  0  1  0            999 V2000
    2.9218   -1.6733    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.3915   -2.3053    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5791   -2.1620    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.6737   -3.0805    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -3.7125    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.6131   -3.0805    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -4.1250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -4.9500    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.5724   -5.3625    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -5.3625    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.1434   -6.1875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -4.9500    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.7145   -5.3625    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -6.1875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -6.6000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -6.6000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -7.4250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -7.8375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -8.6625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289   -9.0750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1434   -8.6625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8579   -9.0750    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1434   -7.8375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289   -7.4250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -4.1250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0  0  0  0
  2  3  1  0  0  0  0
  2  4  1  0  0  0  0
  5  4  1  6  0  0  0
  5  6  1  1  0  0  0
  5  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  1  0  0  0
  8 10  1  0  0  0  0
 10 11  1  1  0  0  0
 10 12  1  0  0  0  0
 12 13  1  6  0  0  0
 13 14  1  0  0  0  0
 14 15  2  0  0  0  0
 14 16  1  0  0  0  0
 16 17  2  0  0  0  0
 17 18  1  0  0  0  0
 18 19  2  0  0  0  0
 19 20  1  0  0  0  0
 20 21  2  0  0  0  0
 21 22  1  0  0  0  0
 21 23  1  0  0  0  0
 23 24  2  0  0  0  0
 18 24  1  0  0  0  0
 12 25  1  0  0  0  0
  5 25  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0259495

> <DATABASE_NAME>
NP-MRD

> <SMILES>
O[C@@H]1C[C@@](O)(CC(O)=O)C[C@@H](OC(=O)\C=C\C2=CC=C(O)C=C2)[C@@H]1O

> <INCHI_IDENTIFIER>
InChI=1S/C17H20O8/c18-11-4-1-10(2-5-11)3-6-15(22)25-13-8-17(24,9-14(20)21)7-12(19)16(13)23/h1-6,12-13,16,18-19,23-24H,7-9H2,(H,20,21)/b6-3+/t12-,13-,16-,17+/m1/s1

> <INCHI_KEY>
GJZFYEMLDRKGMP-WNWKMIQMSA-N

> <FORMULA>
C17H20O8

> <MOLECULAR_WEIGHT>
352.339

> <EXACT_MASS>
352.115817604

> <JCHEM_ACCEPTOR_COUNT>
7

> <JCHEM_ATOM_COUNT>
45

> <JCHEM_AVERAGE_POLARIZABILITY>
34.449452602465655

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
5

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
2-[(1S,3R,4R,5R)-1,3,4-trihydroxy-5-{[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy}cyclohexyl]acetic acid

> <JCHEM_LOGP>
-0.03233013533333355

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
2

> <JCHEM_PHYSIOLOGICAL_CHARGE>
-1

> <JCHEM_PKA>
9.398519876561126

> <JCHEM_PKA_STRONGEST_ACIDIC>
3.952859767610566

> <JCHEM_PKA_STRONGEST_BASIC>
-3.091392611872748

> <JCHEM_POLAR_SURFACE_AREA>
144.52

> <JCHEM_REFRACTIVITY>
85.803

> <JCHEM_ROTATABLE_BOND_COUNT>
6

> <JCHEM_RULE_OF_FIVE>
1

> <JCHEM_TRADITIONAL_IUPAC>
[(1S,3R,4R,5R)-1,3,4-trihydroxy-5-{[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy}cyclohexyl]acetic acid

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 08-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   08-SEP-22         0                                  
HETATM    1  O   UNK     0       5.454  -3.123   0.000  0.00  0.00           O+0
HETATM    2  C   UNK     0       4.464  -4.303   0.000  0.00  0.00           C+0
HETATM    3  O   UNK     0       2.948  -4.036   0.000  0.00  0.00           O+0
HETATM    4  C   UNK     0       4.991  -5.750   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       4.001  -6.930   0.000  0.00  0.00           C+0
HETATM    6  O   UNK     0       3.011  -5.750   0.000  0.00  0.00           O+0
HETATM    7  C   UNK     0       5.335  -7.700   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       5.335  -9.240   0.000  0.00  0.00           C+0
HETATM    9  O   UNK     0       6.668 -10.010   0.000  0.00  0.00           O+0
HETATM   10  C   UNK     0       4.001 -10.010   0.000  0.00  0.00           C+0
HETATM   11  O   UNK     0       4.001 -11.550   0.000  0.00  0.00           O+0
HETATM   12  C   UNK     0       2.667  -9.240   0.000  0.00  0.00           C+0
HETATM   13  O   UNK     0       1.334 -10.010   0.000  0.00  0.00           O+0
HETATM   14  C   UNK     0       1.334 -11.550   0.000  0.00  0.00           C+0
HETATM   15  O   UNK     0       2.667 -12.320   0.000  0.00  0.00           O+0
HETATM   16  C   UNK     0       0.000 -12.320   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       0.000 -13.860   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0      -1.334 -14.630   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0      -1.334 -16.170   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0      -2.667 -16.940   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0      -4.001 -16.170   0.000  0.00  0.00           C+0
HETATM   22  O   UNK     0      -5.335 -16.940   0.000  0.00  0.00           O+0
HETATM   23  C   UNK     0      -4.001 -14.630   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0      -2.667 -13.860   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0       2.667  -7.700   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3    4                                                  
CONECT    3    2                                                            
CONECT    4    2    5                                                       
CONECT    5    4    6    7   25                                             
CONECT    6    5                                                            
CONECT    7    5    8                                                       
CONECT    8    7    9   10                                                  
CONECT    9    8                                                            
CONECT   10    8   11   12                                                  
CONECT   11   10                                                            
CONECT   12   10   13   25                                                  
CONECT   13   12   14                                                       
CONECT   14   13   15   16                                                  
CONECT   15   14                                                            
CONECT   16   14   17                                                       
CONECT   17   16   18                                                       
CONECT   18   17   19   24                                                  
CONECT   19   18   20                                                       
CONECT   20   19   21                                                       
CONECT   21   20   22   23                                                  
CONECT   22   21                                                            
CONECT   23   21   24                                                       
CONECT   24   23   18                                                       
CONECT   25   12    5                                                       
MASTER        0    0    0    0    0    0    0    0   25    0   52    0
END

View in JSmol

Synonyms

Value	Source
(1S)-5a-[[3-(4-Hydroxyphenyl)-1-oxo-2-propenyl]oxy]-1b,3b,4b-trihydroxycyclohexane-1-acetate	Generator
(1S)-5a-[[3-(4-Hydroxyphenyl)-1-oxo-2-propenyl]oxy]-1b,3b,4b-trihydroxycyclohexane-1-acetic acid	Generator
(1S)-5alpha-[[3-(4-Hydroxyphenyl)-1-oxo-2-propenyl]oxy]-1beta,3beta,4beta-trihydroxycyclohexane-1-acetate	Generator
(1S)-5Α-[[3-(4-hydroxyphenyl)-1-oxo-2-propenyl]oxy]-1β,3β,4β-trihydroxycyclohexane-1-acetate	Generator
(1S)-5Α-[[3-(4-hydroxyphenyl)-1-oxo-2-propenyl]oxy]-1β,3β,4β-trihydroxycyclohexane-1-acetic acid	Generator

Chemical Formula

C₁₇H₂₀O₈

Average Mass

352.3390 Da

Monoisotopic Mass

352.11582 Da

IUPAC Name

2-[(1S,3R,4R,5R)-1,3,4-trihydroxy-5-{[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy}cyclohexyl]acetic acid

Traditional Name

[(1S,3R,4R,5R)-1,3,4-trihydroxy-5-{[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy}cyclohexyl]acetic acid

CAS Registry Number

Not Available

SMILES

O[C@@H]1C[C@@](O)(CC(O)=O)C[C@@H](OC(=O)\C=C\C2=CC=C(O)C=C2)[C@@H]1O

InChI Identifier

InChI=1S/C17H20O8/c18-11-4-1-10(2-5-11)3-6-15(22)25-13-8-17(24,9-14(20)21)7-12(19)16(13)23/h1-6,12-13,16,18-19,23-24H,7-9H2,(H,20,21)/b6-3+/t12-,13-,16-,17+/m1/s1

InChI Key

GJZFYEMLDRKGMP-WNWKMIQMSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Onobrychis viciifolia	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as coumaric acid esters. These are aromatic compounds containing an ester derivative of coumaric acid.

Kingdom

Organic compounds

Super Class

Phenylpropanoids and polyketides

Class

Cinnamic acids and derivatives

Sub Class

Hydroxycinnamic acids and derivatives

Direct Parent

Coumaric acid esters

Alternative Parents

Substituents

Coumaric acid ester
Coumaric acid or derivatives
Cinnamic acid ester
Styrene
1-hydroxy-2-unsubstituted benzenoid
Cyclohexanol
Fatty acid ester
Phenol
Cyclitol or derivatives
Dicarboxylic acid or derivatives
Monocyclic benzene moiety
Fatty acyl
Benzenoid
Cyclic alcohol
Alpha,beta-unsaturated carboxylic ester
Tertiary alcohol
Enoate ester
Carboxylic acid ester
Secondary alcohol
Carboxylic acid derivative
Carboxylic acid
Polyol
Hydrocarbon derivative
Alcohol
Carbonyl group
Organic oxide
Organic oxygen compound
Organooxygen compound
Aromatic homomonocyclic compound

Molecular Framework

Aromatic homomonocyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	-0.032	ChemAxon
pKa (Strongest Acidic)	3.95	ChemAxon
pKa (Strongest Basic)	-3.1	ChemAxon
Physiological Charge	-1	ChemAxon
Hydrogen Acceptor Count	7	ChemAxon
Hydrogen Donor Count	5	ChemAxon
Polar Surface Area	144.52 Å²	ChemAxon
Rotatable Bond Count	6	ChemAxon
Refractivity	85.8 m³·mol⁻¹	ChemAxon
Polarizability	34.45 Å³	ChemAxon
Number of Rings	2	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

8745379

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

10569992

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for [(1s,3r,4r,5r)-1,3,4-trihydroxy-5-{[(2e)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy}cyclohexyl]acetic acid (NP0259495)

MOL for NP0259495 ([(1s,3r,4r,5r)-1,3,4-trihydroxy-5-{[(2e)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy}cyclohexyl]acetic acid)

3D MOL for NP0259495 ([(1s,3r,4r,5r)-1,3,4-trihydroxy-5-{[(2e)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy}cyclohexyl]acetic acid)

3D SDF for NP0259495 ([(1s,3r,4r,5r)-1,3,4-trihydroxy-5-{[(2e)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy}cyclohexyl]acetic acid)

3D-SDF for NP0259495 ([(1s,3r,4r,5r)-1,3,4-trihydroxy-5-{[(2e)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy}cyclohexyl]acetic acid)

PDB for NP0259495 ([(1s,3r,4r,5r)-1,3,4-trihydroxy-5-{[(2e)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy}cyclohexyl]acetic acid)

3D PDB for NP0259495 ([(1s,3r,4r,5r)-1,3,4-trihydroxy-5-{[(2e)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy}cyclohexyl]acetic acid)

SMILES for NP0259495 ([(1s,3r,4r,5r)-1,3,4-trihydroxy-5-{[(2e)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy}cyclohexyl]acetic acid)

INCHI for NP0259495 ([(1s,3r,4r,5r)-1,3,4-trihydroxy-5-{[(2e)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy}cyclohexyl]acetic acid)

Structure for NP0259495 ([(1s,3r,4r,5r)-1,3,4-trihydroxy-5-{[(2e)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy}cyclohexyl]acetic acid)

3D Structure for NP0259495 ([(1s,3r,4r,5r)-1,3,4-trihydroxy-5-{[(2e)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy}cyclohexyl]acetic acid)