NP-MRD: Showing NP-Card for (1s,2r,3s,4r)-3-hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl acetate (NP0255313)

Jump To Section:

Identification Spectra BioTaxonomy ChemoTaxonomy Physical properties Links References XML

Record Information

Version

2.0

Created at

2022-09-07 19:45:54 UTC

Updated at

2022-09-07 19:45:54 UTC

NP-MRD ID

NP0255313

Secondary Accession Numbers

None

Natural Product Identification

Common Name

(1s,2r,3s,4r)-3-hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl acetate

Description

(1S,2R,3S,4R)-3-hydroxy-1,7,7-trimethylbicyclo[2.2.1]Heptan-2-yl acetate belongs to the class of organic compounds known as bicyclic monoterpenoids. These are monoterpenoids containing exactly 2 rings, which are fused to each other. (1s,2r,3s,4r)-3-hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl acetate is found in Artemisia vulgaris. Based on a literature review very few articles have been published on (1S,2R,3S,4R)-3-hydroxy-1,7,7-trimethylbicyclo[2.2.1]Heptan-2-yl acetate.

Structure

MOL SDF PDB SMILES InChI


  Mrv1652309072221452D          

 15 16  0  0  1  0            999 V2000
   -1.0854    2.5017    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3322    2.1650    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3360    2.6489    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2428    1.3017    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.2733    0.5639    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.2543   -0.2609    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.1219   -1.1218    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.8472   -0.6569    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.5709   -0.2609    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5899    0.5639    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8850    0.9927    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.1484    1.8188    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6599    0.1726    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2727    0.6314    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3084   -0.1303    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  2  0  0  0  0
  2  4  1  0  0  0  0
  5  4  1  6  0  0  0
  5  6  1  0  0  0  0
  6  7  1  6  0  0  0
  6  8  1  0  0  0  0
  8  9  1  1  0  0  0
  9 10  1  0  0  0  0
 10 11  1  0  0  0  0
  5 11  1  0  0  0  0
 11 12  1  6  0  0  0
 11 13  1  0  0  0  0
  8 13  1  0  0  0  0
 13 14  1  0  0  0  0
 13 15  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0255313

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CC(=O)O[C@H]1[C@@H](O)[C@@H]2CC[C@@]1(C)C2(C)C

> <INCHI_IDENTIFIER>
InChI=1S/C12H20O3/c1-7(13)15-10-9(14)8-5-6-12(10,4)11(8,2)3/h8-10,14H,5-6H2,1-4H3/t8-,9-,10-,12+/m0/s1

> <INCHI_KEY>
QRRSWTCVSAQEPQ-QFOLPQNPSA-N

> <FORMULA>
C12H20O3

> <MOLECULAR_WEIGHT>
212.289

> <EXACT_MASS>
212.141244504

> <JCHEM_ACCEPTOR_COUNT>
2

> <JCHEM_ATOM_COUNT>
35

> <JCHEM_AVERAGE_POLARIZABILITY>
23.3403918685487

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
1

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
(1S,2R,3S,4R)-3-hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl acetate

> <JCHEM_LOGP>
1.433633417666666

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
2

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA_STRONGEST_ACIDIC>
13.895902046511935

> <JCHEM_PKA_STRONGEST_BASIC>
-3.2817324448556784

> <JCHEM_POLAR_SURFACE_AREA>
46.53

> <JCHEM_REFRACTIVITY>
55.750299999999996

> <JCHEM_ROTATABLE_BOND_COUNT>
2

> <JCHEM_RULE_OF_FIVE>
1

> <JCHEM_TRADITIONAL_IUPAC>
(1S,2R,3S,4R)-3-hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl acetate

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 07-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   07-SEP-22         0                                  
HETATM    1  C   UNK     0      -2.026   4.670   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      -0.620   4.041   0.000  0.00  0.00           C+0
HETATM    3  O   UNK     0       0.627   4.945   0.000  0.00  0.00           O+0
HETATM    4  O   UNK     0      -0.453   2.430   0.000  0.00  0.00           O+0
HETATM    5  C   UNK     0       0.510   1.053   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       0.475  -0.487   0.000  0.00  0.00           C+0
HETATM    7  O   UNK     0       0.228  -2.094   0.000  0.00  0.00           O+0
HETATM    8  C   UNK     0       1.581  -1.226   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       2.932  -0.487   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       2.968   1.053   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       1.652   1.853   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       2.144   3.395   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       1.232   0.322   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0      -0.509   1.179   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0      -0.576  -0.243   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3    4                                                  
CONECT    3    2                                                            
CONECT    4    2    5                                                       
CONECT    5    4    6   11                                                  
CONECT    6    5    7    8                                                  
CONECT    7    6                                                            
CONECT    8    6    9   13                                                  
CONECT    9    8   10                                                       
CONECT   10    9   11                                                       
CONECT   11   10    5   12   13                                             
CONECT   12   11                                                            
CONECT   13   11    8   14   15                                             
CONECT   14   13                                                            
CONECT   15   13                                                            
MASTER        0    0    0    0    0    0    0    0   15    0   32    0
END

View in JSmol

Synonyms

Value	Source
(1S,2R,3S,4R)-3-Hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl acetic acid	Generator

Chemical Formula

C₁₂H₂₀O₃

Average Mass

212.2890 Da

Monoisotopic Mass

212.14124 Da

IUPAC Name

(1S,2R,3S,4R)-3-hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl acetate

Traditional Name

(1S,2R,3S,4R)-3-hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl acetate

CAS Registry Number

Not Available

SMILES

CC(=O)O[C@H]1[C@@H](O)[C@@H]2CC[C@@]1(C)C2(C)C

InChI Identifier

InChI=1S/C12H20O3/c1-7(13)15-10-9(14)8-5-6-12(10,4)11(8,2)3/h8-10,14H,5-6H2,1-4H3/t8-,9-,10-,12+/m0/s1

InChI Key

QRRSWTCVSAQEPQ-QFOLPQNPSA-N

Experimental Spectra

Not Available

Predicted Spectra

Not Available

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Artemisia vulgaris	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as bicyclic monoterpenoids. These are monoterpenoids containing exactly 2 rings, which are fused to each other.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Prenol lipids

Sub Class

Monoterpenoids

Direct Parent

Bicyclic monoterpenoids

Alternative Parents

Substituents

Bicyclic monoterpenoid
Bornane monoterpenoid
Cyclic alcohol
Secondary alcohol
Carboxylic acid ester
Monocarboxylic acid or derivatives
Carboxylic acid derivative
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Carbonyl group
Alcohol
Aliphatic homopolycyclic compound

Molecular Framework

Aliphatic homopolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	1.43	ChemAxon
pKa (Strongest Acidic)	13.9	ChemAxon
pKa (Strongest Basic)	-3.3	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	2	ChemAxon
Hydrogen Donor Count	1	ChemAxon
Polar Surface Area	46.53 Å²	ChemAxon
Rotatable Bond Count	2	ChemAxon
Refractivity	55.75 m³·mol⁻¹	ChemAxon
Polarizability	23.34 Å³	ChemAxon
Number of Rings	2	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

162914132

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for (1s,2r,3s,4r)-3-hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl acetate (NP0255313)

MOL for NP0255313 ((1s,2r,3s,4r)-3-hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl acetate)

3D MOL for NP0255313 ((1s,2r,3s,4r)-3-hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl acetate)

3D SDF for NP0255313 ((1s,2r,3s,4r)-3-hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl acetate)

3D-SDF for NP0255313 ((1s,2r,3s,4r)-3-hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl acetate)

PDB for NP0255313 ((1s,2r,3s,4r)-3-hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl acetate)

3D PDB for NP0255313 ((1s,2r,3s,4r)-3-hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl acetate)

SMILES for NP0255313 ((1s,2r,3s,4r)-3-hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl acetate)

INCHI for NP0255313 ((1s,2r,3s,4r)-3-hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl acetate)

Structure for NP0255313 ((1s,2r,3s,4r)-3-hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl acetate)

3D Structure for NP0255313 ((1s,2r,3s,4r)-3-hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl acetate)