Record Information |
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Version | 2.0 |
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Created at | 2022-09-07 16:32:15 UTC |
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Updated at | 2022-09-07 16:32:15 UTC |
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NP-MRD ID | NP0252866 |
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Secondary Accession Numbers | None |
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Natural Product Identification |
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Common Name | (3r,4ar,9ar)-4a,7-dihydroxy-3-(3-hydroxyprop-1-en-2-yl)-1,2,3,9a-tetrahydroxanthene-4,9-dione |
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Description | Applanatin A belongs to the class of organic compounds known as xanthones. These are polycyclic aromatic compounds containing a xanthene moiety conjugated to a ketone group at carbon 9. Xanthene is a tricyclic compound made up of two benzene rings linearly fused to each other through a pyran ring. (3r,4ar,9ar)-4a,7-dihydroxy-3-(3-hydroxyprop-1-en-2-yl)-1,2,3,9a-tetrahydroxanthene-4,9-dione is found in Ganoderma applanatum. It was first documented in 2022 (PMID: 36091400). Based on a literature review a significant number of articles have been published on Applanatin A (PMID: 36087713) (PMID: 36083970) (PMID: 36082849) (PMID: 36088383). |
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Structure | OCC(=C)[C@H]1CC[C@@H]2C(=O)C3=CC(O)=CC=C3O[C@@]2(O)C1=O InChI=1S/C16H16O6/c1-8(7-17)10-3-4-12-14(19)11-6-9(18)2-5-13(11)22-16(12,21)15(10)20/h2,5-6,10,12,17-18,21H,1,3-4,7H2/t10-,12-,16-/m1/s1 |
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Synonyms | Not Available |
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Chemical Formula | C16H16O6 |
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Average Mass | 304.2980 Da |
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Monoisotopic Mass | 304.09469 Da |
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IUPAC Name | (3R,4aR,9aR)-4a,7-dihydroxy-3-(3-hydroxyprop-1-en-2-yl)-2,3,4,4a,9,9a-hexahydro-1H-xanthene-4,9-dione |
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Traditional Name | (3R,4aR,9aR)-4a,7-dihydroxy-3-(3-hydroxyprop-1-en-2-yl)-1,2,3,9a-tetrahydroxanthene-4,9-dione |
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CAS Registry Number | Not Available |
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SMILES | OCC(=C)[C@H]1CC[C@@H]2C(=O)C3=CC(O)=CC=C3O[C@@]2(O)C1=O |
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InChI Identifier | InChI=1S/C16H16O6/c1-8(7-17)10-3-4-12-14(19)11-6-9(18)2-5-13(11)22-16(12,21)15(10)20/h2,5-6,10,12,17-18,21H,1,3-4,7H2/t10-,12-,16-/m1/s1 |
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InChI Key | HLIPHTRQCSGMCK-NSODJVPESA-N |
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Experimental Spectra |
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| Not Available | Predicted Spectra |
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| Not Available | Chemical Shift Submissions |
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| Not Available | Species |
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Species of Origin | |
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Chemical Taxonomy |
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Description | Belongs to the class of organic compounds known as xanthones. These are polycyclic aromatic compounds containing a xanthene moiety conjugated to a ketone group at carbon 9. Xanthene is a tricyclic compound made up of two benzene rings linearly fused to each other through a pyran ring. |
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Kingdom | Organic compounds |
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Super Class | Organoheterocyclic compounds |
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Class | Benzopyrans |
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Sub Class | 1-benzopyrans |
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Direct Parent | Xanthones |
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Alternative Parents | |
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Substituents | - Xanthone
- Chromone
- Aryl ketone
- Aryl alkyl ketone
- 1-hydroxy-2-unsubstituted benzenoid
- Benzenoid
- Cyclic alcohol
- Ketone
- Hemiacetal
- Oxacycle
- Hydrocarbon derivative
- Organic oxide
- Primary alcohol
- Organooxygen compound
- Alcohol
- Organic oxygen compound
- Carbonyl group
- Aromatic heteropolycyclic compound
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Molecular Framework | Aromatic heteropolycyclic compounds |
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External Descriptors | Not Available |
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Physical Properties |
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State | Not Available |
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Experimental Properties | Property | Value | Reference |
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Melting Point | Not Available | Not Available | Boiling Point | Not Available | Not Available | Water Solubility | Not Available | Not Available | LogP | Not Available | Not Available |
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Predicted Properties | |
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General References | - O'Byrne LJ, Bodunde EO, Maher GM, Khashan AS, Greene RM, Browne JP, Mccarthy FP: Patient reported outcome measures evaluating postpartum maternal health and wellbeing: a systematic review and evaluation of measurement properties. Am J Obstet Gynecol MFM. 2022 Sep 7:100743. doi: 10.1016/j.ajogmf.2022.100743. [PubMed:36087713 ]
- Panchal N, Desai C, Ghosal R: Fecal glucocorticoid metabolite levels in captive Indian leopards (Panthera pardus fusca) housed under three different enrichment regimes. PLoS One. 2022 Sep 9;17(9):e0261796. doi: 10.1371/journal.pone.0261796. eCollection 2022. [PubMed:36083970 ]
- Polishchuk V, Filatova M, Rusanov E, Shandura M: Trianionic 1,3,2-Dioxaborine-Containing Polymethines: Bright Near-Infrared Fluorophores. Chemistry. 2022 Sep 9. doi: 10.1002/chem.202202168. [PubMed:36082849 ]
- Yuksel S, Bonus M, Schwabe T, Pfleger C, Zimmer T, Enke U, Sass I, Gohlke H, Benndorf K, Kusch J: Uncoupling of Voltage- and Ligand-Induced Activation in HCN2 Channels by Glycine Inserts. Front Physiol. 2022 Aug 25;13:895324. doi: 10.3389/fphys.2022.895324. eCollection 2022. [PubMed:36091400 ]
- Peter A, Balogh A, Csanadi Z, Danko K, Griger Z: Subclinical systolic and diastolic myocardial dysfunction in polyphasic polymyositis/dermatomyositis: a 2-year longitudinal study. Arthritis Res Ther. 2022 Sep 10;24(1):219. doi: 10.1186/s13075-022-02906-7. [PubMed:36088383 ]
- LOTUS database [Link]
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