NP-MRD: Showing NP-Card for 10-(acetyloxy)-9-[(acetyloxy)methyl]-4a-(methoxycarbonyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-2-carboxylic acid (NP0245999)

Jump To Section:

Identification Spectra BioTaxonomy ChemoTaxonomy Physical properties Links References XML

Record Information

Version

2.0

Created at

2022-09-07 07:17:55 UTC

Updated at

2022-09-07 07:17:56 UTC

NP-MRD ID

NP0245999

Secondary Accession Numbers

None

Natural Product Identification

Common Name

10-(acetyloxy)-9-[(acetyloxy)methyl]-4a-(methoxycarbonyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-2-carboxylic acid

Description

10-(Acetyloxy)-9-[(acetyloxy)methyl]-4a-(methoxycarbonyl)-2,6a,6b,9,12a-pentamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylic acid belongs to the class of organic compounds known as triterpenoids. These are terpene molecules containing six isoprene units. 10-(acetyloxy)-9-[(acetyloxy)methyl]-4a-(methoxycarbonyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-2-carboxylic acid is found in Phytolacca acinosa. 10-(Acetyloxy)-9-[(acetyloxy)methyl]-4a-(methoxycarbonyl)-2,6a,6b,9,12a-pentamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylic acid is an extremely weak basic (essentially neutral) compound (based on its pKa).

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1533004181500392D          

 43 47  0  0  0  0            999 V2000
   -0.5230   -6.6809    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1105   -5.9664    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1270   -6.6809    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.1270   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3020   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1105   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3020   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4452   -3.0106    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1270   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5395   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3645   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7770   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6020   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0145   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.8395   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4270   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2520   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0770   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4895   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.3145   -4.5375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.7270   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.3145   -3.1086    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.5520   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0770   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9337   -6.0644    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.8522   -5.5341    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.9955   -6.3466    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.7707   -6.6288    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.4027   -6.0985    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.9140   -7.4412    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2520   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.8395   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0145   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6020   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1895   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7770   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6907   -6.0725    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3645   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5395   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4733   -3.5409    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1053   -4.0712    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6165   -2.7284    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  3  5  1  0  0  0  0
  5  6  1  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  8 10  1  0  0  0  0
 10 11  1  0  0  0  0
  5 11  1  0  0  0  0
 11 12  1  0  0  0  0
 12 13  2  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 16 18  1  0  0  0  0
 18 19  1  0  0  0  0
 19 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  2  0  0  0  0
 22 24  1  0  0  0  0
 20 25  1  0  0  0  0
 25 26  1  0  0  0  0
 25 27  1  0  0  0  0
 27 28  1  0  0  0  0
 28 29  1  0  0  0  0
 29 30  2  0  0  0  0
 29 31  1  0  0  0  0
 25 32  1  0  0  0  0
 16 32  1  0  0  0  0
 32 33  1  0  0  0  0
 33 34  1  0  0  0  0
 34 35  1  0  0  0  0
 15 35  1  0  0  0  0
 35 36  1  0  0  0  0
 35 37  1  0  0  0  0
 12 37  1  0  0  0  0
 37 38  1  0  0  0  0
 37 39  1  0  0  0  0
 39 40  1  0  0  0  0
  5 40  1  0  0  0  0
  8 41  1  0  0  0  0
 41 42  2  0  0  0  0
 41 43  1  0  0  0  0
M  END

     RDKit          3D

 95 99  0  0  0  0  0  0  0  0999 V2000
   -6.7730   -1.9528   -0.3388 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.8369   -0.9181   -0.0999 O   0  0  0  0  0  0  0  0  0  0  0  0
   -5.0496   -0.9377    1.0067 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.2064   -1.9270    1.7963 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0275    0.0524    1.4121 C   0  0  2  0  0  0  0  0  0  0  0  0
   -4.8016    1.2937    1.8042 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.6849    1.6934    0.6597 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9479    1.9059   -0.6097 C   0  0  1  0  0  0  0  0  0  0  0  0
   -5.9789    1.8720   -1.7510 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3811    3.2829   -0.6196 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5649    4.0503    0.3474 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6343    3.7236   -1.7230 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8696    0.9193   -0.9294 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1346    0.4896    0.3066 C   0  0  2  0  0  0  0  0  0  0  0  0
   -2.0176   -0.4502   -0.0304 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5870   -0.6179   -1.2549 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4664   -1.5607   -1.5543 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6401   -1.4129   -0.5293 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.5894   -0.2679   -0.8470 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.8108    1.0192   -1.1097 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1671   -0.6324   -2.2207 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4373   -0.0166   -2.5893 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3990    0.3315   -1.4337 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.1371    1.7014   -1.2158 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.8882    2.7816   -1.4834 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3278    4.1305   -1.1120 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9943    2.7005   -2.0107 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.0583   -0.4090   -0.2148 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.2072   -1.9108   -0.4124 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.9430   -0.0817    0.9449 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.2568   -0.3416    0.9476 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.4317   -0.0940    0.4347 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.6402   -0.8443    0.9627 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.5757    0.7435   -0.4761 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.6384   -0.0270    0.1688 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.3470   -0.5138    1.5538 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8403   -0.5932    1.8494 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1241   -1.4761    0.8712 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.4693   -2.8974    1.3800 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3507   -1.2588    1.0403 C   0  0  2  0  0  0  0  0  0  0  0  0
   -2.1197   -2.5753    1.0754 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7100   -0.5012    2.3028 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1864   -0.4452    2.5654 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1870   -2.8611   -0.5945 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.5284   -1.6848   -1.0965 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.3489   -2.2065    0.5882 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0489    2.1079    1.9441 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3836    1.1224    2.7348 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.6175    1.0839    0.5727 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1160    2.7225    0.9279 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.0842    0.8603   -2.1755 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.9314    2.2110   -1.3443 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.6919    2.5765   -2.5588 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6429    3.5744   -1.7825 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1989    0.0892   -1.5722 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1199    1.4951   -1.5534 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6552    1.4489    0.6881 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0302   -0.0874   -2.0759 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9310   -2.5686   -1.5272 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1553   -1.3957   -2.5916 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.2891   -2.2835   -0.7418 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.4888    1.8427   -1.4097 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.1826    1.3494   -0.2960 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.1422    0.9086   -2.0157 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.1210   -1.7500   -2.3845 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.4321   -0.2762   -3.0176 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.0166   -0.7648   -3.2086 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.3212    0.8571   -3.2617 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.4189    0.1964   -1.7726 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.1223    4.7235   -0.6264 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.8611    4.6062   -1.9806 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.5172    4.0222   -0.3473 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.4851   -2.4576    0.1841 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.2167   -2.1857   -0.0390 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.2651   -2.2005   -1.4905 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.5387   -0.5116    1.9109 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.8411    1.0457    1.1850 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.5792   -1.9148    0.7276 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.7038   -0.7513    2.0656 H   0  0  0  0  0  0  0  0  0  0  0  0
    9.5493   -0.4433    0.4694 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.7281    1.1016    0.2812 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.6960    0.2185    2.3485 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.8527   -1.4488    1.8375 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.8122   -1.0496    2.8866 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.5277    0.4573    1.8731 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0553   -3.1605    2.2847 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.5436   -2.8523    1.6381 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.4448   -3.6187    0.5396 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6037   -2.7659    2.0560 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4979   -3.4685    0.9047 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8753   -2.6402    0.2362 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4489    0.5798    2.0804 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2351   -0.8857    3.2031 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2939    0.3473    3.3709 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6096   -1.3425    3.0608 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  2  0
  5  3  1  6
  5  6  1  0
  6  7  1  0
  7  8  1  0
  8  9  1  0
  8 13  1  0
 13 14  1  0
 14 15  1  0
 15 16  2  0
 16 17  1  0
 17 18  1  0
 18 19  1  0
 19 20  1  6
 19 21  1  0
 21 22  1  0
 22 23  1  0
 23 24  1  0
 24 25  1  0
 25 26  1  0
 25 27  2  0
 23 28  1  0
 28 29  1  6
 28 30  1  0
 30 31  1  0
 31 32  1  0
 32 33  1  0
 32 34  2  0
 28 35  1  0
 35 36  1  0
 36 37  1  0
 37 38  1  0
 38 39  1  1
 38 40  1  0
 40 41  1  1
 40 42  1  0
 42 43  1  0
  8 10  1  1
 10 12  1  0
 10 11  2  0
 14  5  1  0
 40 15  1  0
 43  5  1  0
 38 18  1  0
 35 19  1  0
  1 44  1  0
  1 45  1  0
  1 46  1  0
  6 47  1  0
  6 48  1  0
  7 49  1  0
  7 50  1  0
  9 51  1  0
  9 52  1  0
  9 53  1  0
 13 55  1  0
 13 56  1  0
 14 57  1  1
 16 58  1  0
 17 59  1  0
 17 60  1  0
 18 61  1  1
 20 62  1  0
 20 63  1  0
 20 64  1  0
 21 65  1  0
 21 66  1  0
 22 67  1  0
 22 68  1  0
 23 69  1  6
 26 70  1  0
 26 71  1  0
 26 72  1  0
 29 73  1  0
 29 74  1  0
 29 75  1  0
 30 76  1  0
 30 77  1  0
 33 78  1  0
 33 79  1  0
 33 80  1  0
 35 81  1  1
 36 82  1  0
 36 83  1  0
 37 84  1  0
 37 85  1  0
 39 86  1  0
 39 87  1  0
 39 88  1  0
 41 89  1  0
 41 90  1  0
 41 91  1  0
 42 92  1  0
 42 93  1  0
 43 94  1  0
 43 95  1  0
 12 54  1  0
M  END


  Mrv1533004181500392D          

 43 47  0  0  0  0            999 V2000
   -0.5230   -6.6809    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1105   -5.9664    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1270   -6.6809    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.1270   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3020   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1105   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3020   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4452   -3.0106    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1270   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5395   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3645   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7770   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6020   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0145   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.8395   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4270   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2520   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0770   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4895   -4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.3145   -4.5375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.7270   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.3145   -3.1086    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.5520   -3.8230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0770   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9337   -6.0644    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.8522   -5.5341    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.9955   -6.3466    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.7707   -6.6288    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.4027   -6.0985    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.9140   -7.4412    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2520   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.8395   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0145   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6020   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1895   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7770   -5.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6907   -6.0725    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3645   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5395   -5.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4733   -3.5409    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1053   -4.0712    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6165   -2.7284    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  3  5  1  0  0  0  0
  5  6  1  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  8 10  1  0  0  0  0
 10 11  1  0  0  0  0
  5 11  1  0  0  0  0
 11 12  1  0  0  0  0
 12 13  2  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 16 18  1  0  0  0  0
 18 19  1  0  0  0  0
 19 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  2  0  0  0  0
 22 24  1  0  0  0  0
 20 25  1  0  0  0  0
 25 26  1  0  0  0  0
 25 27  1  0  0  0  0
 27 28  1  0  0  0  0
 28 29  1  0  0  0  0
 29 30  2  0  0  0  0
 29 31  1  0  0  0  0
 25 32  1  0  0  0  0
 16 32  1  0  0  0  0
 32 33  1  0  0  0  0
 33 34  1  0  0  0  0
 34 35  1  0  0  0  0
 15 35  1  0  0  0  0
 35 36  1  0  0  0  0
 35 37  1  0  0  0  0
 12 37  1  0  0  0  0
 37 38  1  0  0  0  0
 37 39  1  0  0  0  0
 39 40  1  0  0  0  0
  5 40  1  0  0  0  0
  8 41  1  0  0  0  0
 41 42  2  0  0  0  0
 41 43  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0245999

> <DATABASE_NAME>
NP-MRD

> <SMILES>
COC(=O)C12CCC(C)(CC1C1=CCC3C4(C)CCC(OC(C)=O)C(C)(COC(C)=O)C4CCC3(C)C1(C)CC2)C(O)=O

> <INCHI_IDENTIFIER>
InChI=1S/C35H52O8/c1-21(36)42-20-32(5)25-11-14-34(7)26(31(25,4)13-12-27(32)43-22(2)37)10-9-23-24-19-30(3,28(38)39)15-17-35(24,29(40)41-8)18-16-33(23,34)6/h9,24-27H,10-20H2,1-8H3,(H,38,39)

> <INCHI_KEY>
FKSHTFZYXULGLP-UHFFFAOYSA-N

> <FORMULA>
C35H52O8

> <MOLECULAR_WEIGHT>
600.793

> <EXACT_MASS>
600.366218634

> <JCHEM_ACCEPTOR_COUNT>
5

> <JCHEM_ATOM_COUNT>
95

> <JCHEM_AVERAGE_POLARIZABILITY>
67.44740411414905

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
1

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
10-(acetyloxy)-9-[(acetyloxy)methyl]-4a-(methoxycarbonyl)-2,6a,6b,9,12a-pentamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylic acid

> <ALOGPS_LOGP>
5.86

> <JCHEM_LOGP>
5.533899752333333

> <ALOGPS_LOGS>
-6.24

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
5

> <JCHEM_PHYSIOLOGICAL_CHARGE>
-1

> <JCHEM_PKA_STRONGEST_ACIDIC>
4.392492842751872

> <JCHEM_PKA_STRONGEST_BASIC>
-6.555794431750414

> <JCHEM_POLAR_SURFACE_AREA>
116.2

> <JCHEM_REFRACTIVITY>
160.18850000000003

> <JCHEM_ROTATABLE_BOND_COUNT>
8

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
3.42e-04 g/l

> <JCHEM_TRADITIONAL_IUPAC>
10-(acetyloxy)-9-[(acetyloxy)methyl]-4a-(methoxycarbonyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-2-carboxylic acid

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 18-APR-15   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   18-APR-15         0                                  
HETATM    1  C   UNK     0      -0.976 -12.471   0.000  0.00  0.00           C+0
HETATM    2  O   UNK     0      -0.206 -11.137   0.000  0.00  0.00           O+0
HETATM    3  C   UNK     0       1.334 -11.137   0.000  0.00  0.00           C+0
HETATM    4  O   UNK     0       2.104 -12.471   0.000  0.00  0.00           O+0
HETATM    5  C   UNK     0       2.104  -9.804   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       0.564  -9.804   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0      -0.206  -8.470   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       0.564  -7.136   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       0.831  -5.620   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       2.104  -7.136   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       2.874  -8.470   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       4.414  -8.470   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       5.184  -7.136   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       6.724  -7.136   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       7.494  -8.470   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       9.034  -8.470   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       8.264  -7.136   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       9.804  -7.136   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0      11.344  -7.136   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0      12.114  -8.470   0.000  0.00  0.00           C+0
HETATM   21  O   UNK     0      13.654  -8.470   0.000  0.00  0.00           O+0
HETATM   22  C   UNK     0      14.424  -7.136   0.000  0.00  0.00           C+0
HETATM   23  O   UNK     0      13.654  -5.803   0.000  0.00  0.00           O+0
HETATM   24  C   UNK     0      15.964  -7.136   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0      11.344  -9.804   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0      11.076 -11.320   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0      12.791 -10.330   0.000  0.00  0.00           C+0
HETATM   28  O   UNK     0      13.058 -11.847   0.000  0.00  0.00           O+0
HETATM   29  C   UNK     0      14.505 -12.374   0.000  0.00  0.00           C+0
HETATM   30  O   UNK     0      15.685 -11.384   0.000  0.00  0.00           O+0
HETATM   31  C   UNK     0      14.773 -13.890   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0       9.804  -9.804   0.000  0.00  0.00           C+0
HETATM   33  C   UNK     0       9.034 -11.137   0.000  0.00  0.00           C+0
HETATM   34  C   UNK     0       7.494 -11.137   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0       6.724  -9.804   0.000  0.00  0.00           C+0
HETATM   36  C   UNK     0       5.954 -11.137   0.000  0.00  0.00           C+0
HETATM   37  C   UNK     0       5.184  -9.804   0.000  0.00  0.00           C+0
HETATM   38  C   UNK     0       5.023 -11.335   0.000  0.00  0.00           C+0
HETATM   39  C   UNK     0       4.414 -11.137   0.000  0.00  0.00           C+0
HETATM   40  C   UNK     0       2.874 -11.137   0.000  0.00  0.00           C+0
HETATM   41  C   UNK     0      -0.883  -6.610   0.000  0.00  0.00           C+0
HETATM   42  O   UNK     0      -2.063  -7.600   0.000  0.00  0.00           O+0
HETATM   43  O   UNK     0      -1.151  -5.093   0.000  0.00  0.00           O+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4    5                                                  
CONECT    4    3                                                            
CONECT    5    3    6   11   40                                             
CONECT    6    5    7                                                       
CONECT    7    6    8                                                       
CONECT    8    7    9   10   41                                             
CONECT    9    8                                                            
CONECT   10    8   11                                                       
CONECT   11   10    5   12                                                  
CONECT   12   11   13   37                                                  
CONECT   13   12   14                                                       
CONECT   14   13   15                                                       
CONECT   15   14   16   35                                                  
CONECT   16   15   17   18   32                                             
CONECT   17   16                                                            
CONECT   18   16   19                                                       
CONECT   19   18   20                                                       
CONECT   20   19   21   25                                                  
CONECT   21   20   22                                                       
CONECT   22   21   23   24                                                  
CONECT   23   22                                                            
CONECT   24   22                                                            
CONECT   25   20   26   27   32                                             
CONECT   26   25                                                            
CONECT   27   25   28                                                       
CONECT   28   27   29                                                       
CONECT   29   28   30   31                                                  
CONECT   30   29                                                            
CONECT   31   29                                                            
CONECT   32   25   16   33                                                  
CONECT   33   32   34                                                       
CONECT   34   33   35                                                       
CONECT   35   34   15   36   37                                             
CONECT   36   35                                                            
CONECT   37   35   12   38   39                                             
CONECT   38   37                                                            
CONECT   39   37   40                                                       
CONECT   40   39    5                                                       
CONECT   41    8   42   43                                                  
CONECT   42   41                                                            
CONECT   43   41                                                            
MASTER        0    0    0    0    0    0    0    0   43    0   94    0
END

View in JSmol

Synonyms

Value	Source
10-(Acetyloxy)-9-[(acetyloxy)methyl]-4a-(methoxycarbonyl)-2,6a,6b,9,12a-pentamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylate	Generator

Chemical Formula

C₃₅H₅₂O₈

Average Mass

600.7930 Da

Monoisotopic Mass

600.36622 Da

IUPAC Name

10-(acetyloxy)-9-[(acetyloxy)methyl]-4a-(methoxycarbonyl)-2,6a,6b,9,12a-pentamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylic acid

Traditional Name

10-(acetyloxy)-9-[(acetyloxy)methyl]-4a-(methoxycarbonyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-2-carboxylic acid

CAS Registry Number

Not Available

SMILES

COC(=O)C12CCC(C)(CC1C1=CCC3C4(C)CCC(OC(C)=O)C(C)(COC(C)=O)C4CCC3(C)C1(C)CC2)C(O)=O

InChI Identifier

InChI=1S/C35H52O8/c1-21(36)42-20-32(5)25-11-14-34(7)26(31(25,4)13-12-27(32)43-22(2)37)10-9-23-24-19-30(3,28(38)39)15-17-35(24,29(40)41-8)18-16-33(23,34)6/h9,24-27H,10-20H2,1-8H3,(H,38,39)

InChI Key

FKSHTFZYXULGLP-UHFFFAOYSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Phytolacca acinosa	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as triterpenoids. These are terpene molecules containing six isoprene units.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Prenol lipids

Sub Class

Triterpenoids

Direct Parent

Triterpenoids

Alternative Parents

Substituents

Triterpenoid
Steroid
Tetracarboxylic acid or derivatives
Methyl ester
Carboxylic acid ester
Carboxylic acid
Carboxylic acid derivative
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Carbonyl group
Aliphatic homopolycyclic compound

Molecular Framework

Aliphatic homopolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	5.86	ALOGPS
logP	5.53	ChemAxon
logS	-6.2	ALOGPS
pKa (Strongest Acidic)	4.39	ChemAxon
pKa (Strongest Basic)	-6.6	ChemAxon
Physiological Charge	-1	ChemAxon
Hydrogen Acceptor Count	5	ChemAxon
Hydrogen Donor Count	1	ChemAxon
Polar Surface Area	116.2 Å²	ChemAxon
Rotatable Bond Count	8	ChemAxon
Refractivity	160.19 m³·mol⁻¹	ChemAxon
Polarizability	67.45 Å³	ChemAxon
Number of Rings	5	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	Yes	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

73810263

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for 10-(acetyloxy)-9-[(acetyloxy)methyl]-4a-(methoxycarbonyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-2-carboxylic acid (NP0245999)

MOL for NP0245999 (10-(acetyloxy)-9-[(acetyloxy)methyl]-4a-(methoxycarbonyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-2-carboxylic acid)

3D MOL for NP0245999 (10-(acetyloxy)-9-[(acetyloxy)methyl]-4a-(methoxycarbonyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-2-carboxylic acid)

3D SDF for NP0245999 (10-(acetyloxy)-9-[(acetyloxy)methyl]-4a-(methoxycarbonyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-2-carboxylic acid)

3D-SDF for NP0245999 (10-(acetyloxy)-9-[(acetyloxy)methyl]-4a-(methoxycarbonyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-2-carboxylic acid)

PDB for NP0245999 (10-(acetyloxy)-9-[(acetyloxy)methyl]-4a-(methoxycarbonyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-2-carboxylic acid)

3D PDB for NP0245999 (10-(acetyloxy)-9-[(acetyloxy)methyl]-4a-(methoxycarbonyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-2-carboxylic acid)

SMILES for NP0245999 (10-(acetyloxy)-9-[(acetyloxy)methyl]-4a-(methoxycarbonyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-2-carboxylic acid)

INCHI for NP0245999 (10-(acetyloxy)-9-[(acetyloxy)methyl]-4a-(methoxycarbonyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-2-carboxylic acid)

Structure for NP0245999 (10-(acetyloxy)-9-[(acetyloxy)methyl]-4a-(methoxycarbonyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-2-carboxylic acid)

3D Structure for NP0245999 (10-(acetyloxy)-9-[(acetyloxy)methyl]-4a-(methoxycarbonyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-2-carboxylic acid)