NP-MRD: Showing NP-Card for methyl (3as,4s,5s,10r,11r,11as)-5-[(2s)-butan-2-yloxy]-11-hydroxy-4-{[(2z)-2-methylbut-2-enoyl]oxy}-3-methylidene-2-oxo-4,5,8,9,11,11a-hexahydro-3ah-spiro[cyclodeca[b]furan-10,2'-oxirane]-6-carboxylate (NP0239560)

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Record Information

Version

2.0

Created at

2022-09-06 23:11:18 UTC

Updated at

2022-09-06 23:11:18 UTC

NP-MRD ID

NP0239560

Secondary Accession Numbers

None

Natural Product Identification

Common Name

methyl (3as,4s,5s,10r,11r,11as)-5-[(2s)-butan-2-yloxy]-11-hydroxy-4-{[(2z)-2-methylbut-2-enoyl]oxy}-3-methylidene-2-oxo-4,5,8,9,11,11a-hexahydro-3ah-spiro[cyclodeca[b]furan-10,2'-oxirane]-6-carboxylate

Description

Methyl (3aS,4S,5S,10R,11R,11aS)-5-[(2S)-butan-2-yloxy]-11-hydroxy-4-{[(2Z)-2-methylbut-2-enoyl]oxy}-3-methylidene-2-oxo-3,3a,4,5,8,9,11,11a-octahydro-2H-spiro[cyclodeca[b]furan-10,2'-oxirane]-6-carboxylate belongs to the class of organic compounds known as germacranolides and derivatives. These are sesquiterpene lactones with a structure based on the germacranolide skeleton, characterized by a gamma lactone fused to a 1,7-dimethylcyclodec-1-ene moiety. Based on a literature review very few articles have been published on methyl (3aS,4S,5S,10R,11R,11aS)-5-[(2S)-butan-2-yloxy]-11-hydroxy-4-{[(2Z)-2-methylbut-2-enoyl]oxy}-3-methylidene-2-oxo-3,3a,4,5,8,9,11,11a-octahydro-2H-spiro[cyclodeca[b]furan-10,2'-oxirane]-6-carboxylate.

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652309072201112D          

 34 36  0  0  1  0            999 V2000
    4.9200    0.6023    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4885    1.1754    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7501    2.0626    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.5445    2.2850    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.1032    2.5747    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.4163    2.1177    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.6387    1.3232    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.0618    0.7334    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.7587    0.2918    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.4896    0.6745    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.5236    1.4988    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.1864    0.2329    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.1524   -0.5914    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9173    0.6155    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9513    1.4398    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2842   -0.0610    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    4.0834   -0.2657    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.3058   -1.0602    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.8055   -1.9915    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
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    5.3273   -2.0593    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7074   -0.6509    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
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    1.4505    2.3094    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.6171    2.3224    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.3948    3.1168    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0  0  0  0
  2  3  1  0  0  0  0
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  8 16  1  0  0  0  0
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 17 18  1  0  0  0  0
 18 19  1  6  0  0  0
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 16 22  1  0  0  0  0
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 31 32  1  0  0  0  0
 30 32  1  6  0  0  0
 30 33  1  0  0  0  0
  6 33  1  0  0  0  0
 33 34  1  6  0  0  0
M  END

     RDKit          3D

 68 70  0  0  0  0  0  0  0  0999 V2000
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M  END


  Mrv1652309072201112D          

 34 36  0  0  1  0            999 V2000
    4.9200    0.6023    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4885    1.1754    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
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 30 33  1  0  0  0  0
  6 33  1  0  0  0  0
 33 34  1  6  0  0  0
M  END
> <DATABASE_ID>
NP0239560

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CC[C@H](C)O[C@@H]1[C@@H](OC(=O)C(\C)=C/C)[C@@H]2[C@H](OC(=O)C2=C)[C@@H](O)[C@]2(CO2)CC\C=C1\C(=O)OC

> <INCHI_IDENTIFIER>
InChI=1S/C25H34O9/c1-7-13(3)22(27)33-19-17-15(5)23(28)34-20(17)21(26)25(12-31-25)11-9-10-16(24(29)30-6)18(19)32-14(4)8-2/h7,10,14,17-21,26H,5,8-9,11-12H2,1-4,6H3/b13-7-,16-10+/t14-,17+,18-,19-,20-,21+,25+/m0/s1

> <INCHI_KEY>
IGZOEDNGFXXMBC-BILXZRRFSA-N

> <FORMULA>
C25H34O9

> <MOLECULAR_WEIGHT>
478.538

> <EXACT_MASS>
478.220282675

> <JCHEM_ACCEPTOR_COUNT>
6

> <JCHEM_ATOM_COUNT>
68

> <JCHEM_AVERAGE_POLARIZABILITY>
49.15895264982127

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
1

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
methyl (3aS,4S,5S,10R,11R,11aS)-5-[(2S)-butan-2-yloxy]-11-hydroxy-4-{[(2Z)-2-methylbut-2-enoyl]oxy}-3-methylidene-2-oxo-3,3a,4,5,8,9,11,11a-octahydro-2H-spiro[cyclodeca[b]furan-10,2'-oxirane]-6-carboxylate

> <JCHEM_LOGP>
3.4831137856666663

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
3

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA_STRONGEST_ACIDIC>
12.936449239445675

> <JCHEM_PKA_STRONGEST_BASIC>
-3.7013971026664594

> <JCHEM_POLAR_SURFACE_AREA>
120.89000000000001

> <JCHEM_REFRACTIVITY>
121.63349999999998

> <JCHEM_ROTATABLE_BOND_COUNT>
8

> <JCHEM_RULE_OF_FIVE>
1

> <JCHEM_TRADITIONAL_IUPAC>
methyl (3aS,4S,5S,10R,11R,11aS)-5-[(2S)-butan-2-yloxy]-11-hydroxy-4-{[(2Z)-2-methylbut-2-enoyl]oxy}-3-methylidene-2-oxo-4,5,8,9,11,11a-hexahydro-3aH-spiro[cyclodeca[b]furan-10,2'-oxirane]-6-carboxylate

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 07-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   07-SEP-22         0                                  
HETATM    1  C   UNK     0       9.184   1.124   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       8.379   2.194   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       8.867   3.850   0.000  0.00  0.00           C+0
HETATM    4  O   UNK     0      10.350   4.265   0.000  0.00  0.00           O+0
HETATM    5  O   UNK     0       7.659   4.806   0.000  0.00  0.00           O+0
HETATM    6  C   UNK     0       6.377   3.953   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       6.792   2.470   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       5.715   1.369   0.000  0.00  0.00           C+0
HETATM    9  O   UNK     0       7.016   0.545   0.000  0.00  0.00           O+0
HETATM   10  C   UNK     0       8.381   1.259   0.000  0.00  0.00           C+0
HETATM   11  O   UNK     0       8.444   2.798   0.000  0.00  0.00           O+0
HETATM   12  C   UNK     0       9.681   0.435   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       9.618  -1.104   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0      11.046   1.149   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0      11.109   2.688   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       6.131  -0.114   0.000  0.00  0.00           C+0
HETATM   17  O   UNK     0       7.622  -0.496   0.000  0.00  0.00           O+0
HETATM   18  C   UNK     0       8.037  -1.979   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       7.104  -3.718   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0       9.529  -2.361   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0       9.944  -3.844   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0       5.054  -1.215   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0       5.469  -2.698   0.000  0.00  0.00           C+0
HETATM   24  O   UNK     0       6.961  -3.080   0.000  0.00  0.00           O+0
HETATM   25  O   UNK     0       4.392  -3.799   0.000  0.00  0.00           O+0
HETATM   26  C   UNK     0       4.807  -5.282   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0       3.562  -0.833   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0       3.147   0.650   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0       4.224   1.751   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0       3.809   3.234   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0       2.325   2.819   0.000  0.00  0.00           C+0
HETATM   32  O   UNK     0       2.708   4.311   0.000  0.00  0.00           O+0
HETATM   33  C   UNK     0       4.885   4.335   0.000  0.00  0.00           C+0
HETATM   34  O   UNK     0       4.470   5.818   0.000  0.00  0.00           O+0
CONECT    1    2                                                            
CONECT    2    1    3    7                                                  
CONECT    3    2    4    5                                                  
CONECT    4    3                                                            
CONECT    5    3    6                                                       
CONECT    6    5    7   33                                                  
CONECT    7    6    2    8                                                  
CONECT    8    7    9   16                                                  
CONECT    9    8   10                                                       
CONECT   10    9   11   12                                                  
CONECT   11   10                                                            
CONECT   12   10   13   14                                                  
CONECT   13   12                                                            
CONECT   14   12   15                                                       
CONECT   15   14                                                            
CONECT   16    8   17   22                                                  
CONECT   17   16   18                                                       
CONECT   18   17   19   20                                                  
CONECT   19   18                                                            
CONECT   20   18   21                                                       
CONECT   21   20                                                            
CONECT   22   16   23   27                                                  
CONECT   23   22   24   25                                                  
CONECT   24   23                                                            
CONECT   25   23   26                                                       
CONECT   26   25                                                            
CONECT   27   22   28                                                       
CONECT   28   27   29                                                       
CONECT   29   28   30                                                       
CONECT   30   29   31   32   33                                             
CONECT   31   30   32                                                       
CONECT   32   31   30                                                       
CONECT   33   30    6   34                                                  
CONECT   34   33                                                            
MASTER        0    0    0    0    0    0    0    0   34    0   72    0
END

View in JSmol

Synonyms

Value	Source
Methyl (3as,4S,5S,10R,11R,11as)-5-[(2S)-butan-2-yloxy]-11-hydroxy-4-{[(2Z)-2-methylbut-2-enoyl]oxy}-3-methylidene-2-oxo-3,3a,4,5,8,9,11,11a-octahydro-2H-spiro[cyclodeca[b]furan-10,2'-oxirane]-6-carboxylic acid	Generator

Chemical Formula

C₂₅H₃₄O₉

Average Mass

478.5380 Da

Monoisotopic Mass

478.22028 Da

IUPAC Name

Not Available

Traditional Name

Not Available

CAS Registry Number

Not Available

SMILES

CC[C@H](C)O[C@@H]1[C@@H](OC(=O)C(\C)=C/C)[C@@H]2[C@H](OC(=O)C2=C)[C@@H](O)[C@]2(CO2)CC\C=C1\C(=O)OC

InChI Identifier

InChI=1S/C25H34O9/c1-7-13(3)22(27)33-19-17-15(5)23(28)34-20(17)21(26)25(12-31-25)11-9-10-16(24(29)30-6)18(19)32-14(4)8-2/h7,10,14,17-21,26H,5,8-9,11-12H2,1-4,6H3/b13-7-,16-10+/t14-,17+,18-,19-,20-,21+,25+/m0/s1

InChI Key

IGZOEDNGFXXMBC-BILXZRRFSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Not Available

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as germacranolides and derivatives. These are sesquiterpene lactones with a structure based on the germacranolide skeleton, characterized by a gamma lactone fused to a 1,7-dimethylcyclodec-1-ene moiety.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Prenol lipids

Sub Class

Terpene lactones

Direct Parent

Germacranolides and derivatives

Alternative Parents

Substituents

Germacranolide
Germacrane sesquiterpenoid
Sesquiterpenoid
Tricarboxylic acid or derivatives
Fatty acid ester
Gamma butyrolactone
Fatty acyl
Alpha,beta-unsaturated carboxylic ester
Enoate ester
Methyl ester
Tetrahydrofuran
Carboxylic acid ester
Secondary alcohol
Lactone
Carboxylic acid derivative
Dialkyl ether
Oxirane
Ether
Oxacycle
Organoheterocyclic compound
Carbonyl group
Alcohol
Organic oxide
Hydrocarbon derivative
Organic oxygen compound
Organooxygen compound
Aliphatic heteropolycyclic compound

Molecular Framework

Aliphatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

162956351

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for methyl (3as,4s,5s,10r,11r,11as)-5-[(2s)-butan-2-yloxy]-11-hydroxy-4-{[(2z)-2-methylbut-2-enoyl]oxy}-3-methylidene-2-oxo-4,5,8,9,11,11a-hexahydro-3ah-spiro[cyclodeca[b]furan-10,2'-oxirane]-6-carboxylate (NP0239560)

MOL for NP0239560 (methyl (3as,4s,5s,10r,11r,11as)-5-[(2s)-butan-2-yloxy]-11-hydroxy-4-{[(2z)-2-methylbut-2-enoyl]oxy}-3-methylidene-2-oxo-4,5,8,9,11,11a-hexahydro-3ah-spiro[cyclodeca[b]furan-10,2'-oxirane]-6-carboxylate)

3D MOL for NP0239560 (methyl (3as,4s,5s,10r,11r,11as)-5-[(2s)-butan-2-yloxy]-11-hydroxy-4-{[(2z)-2-methylbut-2-enoyl]oxy}-3-methylidene-2-oxo-4,5,8,9,11,11a-hexahydro-3ah-spiro[cyclodeca[b]furan-10,2'-oxirane]-6-carboxylate)

3D SDF for NP0239560 (methyl (3as,4s,5s,10r,11r,11as)-5-[(2s)-butan-2-yloxy]-11-hydroxy-4-{[(2z)-2-methylbut-2-enoyl]oxy}-3-methylidene-2-oxo-4,5,8,9,11,11a-hexahydro-3ah-spiro[cyclodeca[b]furan-10,2'-oxirane]-6-carboxylate)

3D-SDF for NP0239560 (methyl (3as,4s,5s,10r,11r,11as)-5-[(2s)-butan-2-yloxy]-11-hydroxy-4-{[(2z)-2-methylbut-2-enoyl]oxy}-3-methylidene-2-oxo-4,5,8,9,11,11a-hexahydro-3ah-spiro[cyclodeca[b]furan-10,2'-oxirane]-6-carboxylate)

PDB for NP0239560 (methyl (3as,4s,5s,10r,11r,11as)-5-[(2s)-butan-2-yloxy]-11-hydroxy-4-{[(2z)-2-methylbut-2-enoyl]oxy}-3-methylidene-2-oxo-4,5,8,9,11,11a-hexahydro-3ah-spiro[cyclodeca[b]furan-10,2'-oxirane]-6-carboxylate)

3D PDB for NP0239560 (methyl (3as,4s,5s,10r,11r,11as)-5-[(2s)-butan-2-yloxy]-11-hydroxy-4-{[(2z)-2-methylbut-2-enoyl]oxy}-3-methylidene-2-oxo-4,5,8,9,11,11a-hexahydro-3ah-spiro[cyclodeca[b]furan-10,2'-oxirane]-6-carboxylate)

SMILES for NP0239560 (methyl (3as,4s,5s,10r,11r,11as)-5-[(2s)-butan-2-yloxy]-11-hydroxy-4-{[(2z)-2-methylbut-2-enoyl]oxy}-3-methylidene-2-oxo-4,5,8,9,11,11a-hexahydro-3ah-spiro[cyclodeca[b]furan-10,2'-oxirane]-6-carboxylate)

INCHI for NP0239560 (methyl (3as,4s,5s,10r,11r,11as)-5-[(2s)-butan-2-yloxy]-11-hydroxy-4-{[(2z)-2-methylbut-2-enoyl]oxy}-3-methylidene-2-oxo-4,5,8,9,11,11a-hexahydro-3ah-spiro[cyclodeca[b]furan-10,2'-oxirane]-6-carboxylate)

Structure for NP0239560 (methyl (3as,4s,5s,10r,11r,11as)-5-[(2s)-butan-2-yloxy]-11-hydroxy-4-{[(2z)-2-methylbut-2-enoyl]oxy}-3-methylidene-2-oxo-4,5,8,9,11,11a-hexahydro-3ah-spiro[cyclodeca[b]furan-10,2'-oxirane]-6-carboxylate)

3D Structure for NP0239560 (methyl (3as,4s,5s,10r,11r,11as)-5-[(2s)-butan-2-yloxy]-11-hydroxy-4-{[(2z)-2-methylbut-2-enoyl]oxy}-3-methylidene-2-oxo-4,5,8,9,11,11a-hexahydro-3ah-spiro[cyclodeca[b]furan-10,2'-oxirane]-6-carboxylate)