NP-MRD: Showing NP-Card for 17?,21?-epoxyhopan-3-one (NP0237330)

Jump To Section:

Identification Spectra BioTaxonomy ChemoTaxonomy Physical properties Links References XML

Record Information

Version

2.0

Created at

2022-09-06 20:26:38 UTC

Updated at

2022-09-06 20:26:38 UTC

NP-MRD ID

NP0237330

Secondary Accession Numbers

None

Natural Product Identification

Common Name

17?,21?-epoxyhopan-3-one

Description

17Beta,21beta-epoxyhopan-3-one belongs to the class of organic compounds known as hopanoids. These are terpenoids containing hopane skeleton(A'-Neogammacerane), a pentacyclic structure with four cyclohexane rings and one cyclopentane ring (and often, a side chain emerging from C30). 17?,21?-epoxyhopan-3-one is found in Gentiana scabra. 17?,21?-epoxyhopan-3-one was first documented in 2011 (PMID: 21438586). Based on a literature review very few articles have been published on 17beta,21beta-epoxyhopan-3-one.

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652309062222262D          

 32 37  0  0  1  0            999 V2000
   -0.2839   -0.4484    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1008    0.2814    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3389    0.9794    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9252    0.3131    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.9798    1.1363    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7796    1.3387    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2192    0.6406    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.6781    1.3262    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.0322    0.5003    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.5603    1.1341    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3732    0.9938    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.6582    0.2195    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    5.4711    0.0792    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    5.1862    0.8534    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9992    0.7130    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.8121    0.5727    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.0971   -0.2016    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.9100   -0.3419    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.5690   -0.8354    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.2850   -1.2454    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.2896   -1.6117    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7561   -0.6951    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    5.2280   -1.3289    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4150   -1.1886    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.1301   -0.4143    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.6021   -1.0482    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3171   -0.2740    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.0926   -1.0678    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7891   -0.9078    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9761   -0.7675    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6912    0.0068    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.0429   -0.5035    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  4  2  1  1  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  1  0  0  0
  7  9  1  0  0  0  0
  9 10  1  1  0  0  0
 10 11  1  0  0  0  0
 12 11  1  6  0  0  0
 12 13  1  0  0  0  0
 13 14  1  6  0  0  0
 13 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  2  0  0  0  0
 17 19  1  0  0  0  0
 19 20  1  0  0  0  0
 19 21  1  0  0  0  0
 19 22  1  0  0  0  0
 13 22  1  0  0  0  0
 22 23  1  6  0  0  0
 23 24  1  0  0  0  0
 24 25  1  0  0  0  0
 12 25  1  0  0  0  0
 25 26  1  6  0  0  0
 25 27  1  0  0  0  0
  9 27  1  0  0  0  0
 27 28  1  1  0  0  0
 27 29  1  0  0  0  0
 29 30  1  0  0  0  0
 30 31  1  0  0  0  0
  4 31  1  0  0  0  0
  7 31  1  0  0  0  0
 31 32  1  6  0  0  0
  4 32  1  0  0  0  0
M  END

     RDKit          3D

 80 85  0  0  0  0  0  0  0  0999 V2000
   -5.7703    1.6818   -1.8778 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.9561    0.7881   -0.6936 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.9381    1.4241    0.2807 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6818    0.3812   -0.0248 C   0  0  1  0  0  0  0  0  0  0  0  0
   -4.8997   -0.5356    1.1880 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4793   -0.6965    1.6867 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7253   -0.8449    0.3513 C   0  0  2  0  0  0  0  0  0  0  0  0
   -2.9781   -2.2062   -0.1334 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3033   -0.4600    0.6420 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.5781   -1.3531    1.5593 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8637   -1.5728    1.3577 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5571   -0.7265    0.3603 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.0347   -0.4773    0.6915 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.2896    0.2266    1.9475 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6149   -1.8927    0.7896 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.1024   -1.9091    0.8089 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.6349   -1.1230   -0.3292 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.5088   -1.6150   -1.0095 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.0966    0.2121   -0.5979 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7048    1.2865    0.2680 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.4680    0.5863   -2.0429 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6071    0.1595   -0.5460 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.9488    1.4943   -0.8288 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5073    1.2230   -1.1555 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8058    0.4857   -0.0594 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.5432    1.4604    1.0453 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5199   -0.0782   -0.6109 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.2852   -1.2447   -1.5180 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2090    0.9816   -1.3961 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6598    0.6594   -1.6500 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4067    0.2513   -0.4356 C   0  0  1  0  0  0  0  0  0  0  0  0
   -3.7801    1.4306    0.3582 O   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3721    1.1428   -2.7402 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.2389    2.6259   -1.6349 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.8060    2.0166   -2.1838 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.4461   -0.1421   -1.0516 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.4970    2.2317    0.8666 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.3732    0.6139    0.9149 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.7976    1.7880   -0.3486 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3899   -1.4688    0.9236 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.5463   -0.0225    1.9382 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2051    0.2700    2.1695 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3345   -1.5624    2.3343 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8670   -2.7024    0.3625 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3018   -2.1410   -1.2146 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1799   -2.9327   -0.0974 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4272    0.5408    1.1677 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0974   -2.3602    1.5277 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7751   -1.0309    2.6289 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.0902   -2.6584    1.1210 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.4137   -1.4349    2.3394 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.6761   -1.3345   -0.5933 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.1828   -0.2440    2.4612 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.5054    0.2440    2.7031 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.6190    1.3005    1.8239 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.2518   -2.2864    1.7785 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.2175   -2.5524    0.0224 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.5565   -1.5788    1.7659 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.4004   -2.9957    0.7190 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.9311    0.9540    1.2927 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.1227    2.2035    0.1867 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.7115    1.5202   -0.1906 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.5278    1.7110   -2.1079 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.6640    0.2948   -2.7483 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.4582    0.1980   -2.2996 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.2866   -0.5076   -1.4031 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.4250    1.8697   -1.7801 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.0999    2.2397   -0.0540 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.4426    0.7778   -2.1438 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.0089    2.2338   -1.2322 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2605    2.1678    0.8092 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.3514    1.0331    2.0215 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.4653    2.1029    1.1560 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1073   -2.1985   -1.0391 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.5059   -1.0292   -2.2317 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2253   -1.3659   -2.1294 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1405    1.9953   -1.0157 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7211    0.9996   -2.4159 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1189    1.5881   -2.0531 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8026   -0.1112   -2.4392 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  4  2  1  6
  4  5  1  0
  5  6  1  0
  6  7  1  0
  7  8  1  6
  7  9  1  0
  9 10  1  0
 10 11  1  0
 11 12  1  0
 12 13  1  0
 13 14  1  1
 13 15  1  0
 15 16  1  0
 16 17  1  0
 17 18  2  0
 17 19  1  0
 19 20  1  0
 19 21  1  0
 19 22  1  0
 22 23  1  0
 23 24  1  0
 24 25  1  0
 25 26  1  1
 25 27  1  0
 27 28  1  6
 27 29  1  0
 29 30  1  0
 30 31  1  0
 31 32  1  1
 31  4  1  0
 32  4  1  0
 31  7  1  0
 27  9  1  0
 25 12  1  0
 22 13  1  0
  1 33  1  0
  1 34  1  0
  1 35  1  0
  2 36  1  0
  3 37  1  0
  3 38  1  0
  3 39  1  0
  5 40  1  0
  5 41  1  0
  6 42  1  0
  6 43  1  0
  8 44  1  0
  8 45  1  0
  8 46  1  0
  9 47  1  1
 10 48  1  0
 10 49  1  0
 11 50  1  0
 11 51  1  0
 12 52  1  6
 14 53  1  0
 14 54  1  0
 14 55  1  0
 15 56  1  0
 15 57  1  0
 16 58  1  0
 16 59  1  0
 20 60  1  0
 20 61  1  0
 20 62  1  0
 21 63  1  0
 21 64  1  0
 21 65  1  0
 22 66  1  6
 23 67  1  0
 23 68  1  0
 24 69  1  0
 24 70  1  0
 26 71  1  0
 26 72  1  0
 26 73  1  0
 28 74  1  0
 28 75  1  0
 28 76  1  0
 29 77  1  0
 29 78  1  0
 30 79  1  0
 30 80  1  0
M  END


  Mrv1652309062222262D          

 32 37  0  0  1  0            999 V2000
   -0.2839   -0.4484    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1008    0.2814    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3389    0.9794    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9252    0.3131    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.9798    1.1363    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7796    1.3387    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2192    0.6406    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.6781    1.3262    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.0322    0.5003    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.5603    1.1341    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3732    0.9938    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.6582    0.2195    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    5.4711    0.0792    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    5.1862    0.8534    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9992    0.7130    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.8121    0.5727    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.0971   -0.2016    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.9100   -0.3419    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.5690   -0.8354    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.2850   -1.2454    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.2896   -1.6117    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7561   -0.6951    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    5.2280   -1.3289    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4150   -1.1886    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.1301   -0.4143    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.6021   -1.0482    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3171   -0.2740    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.0926   -1.0678    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7891   -0.9078    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9761   -0.7675    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6912    0.0068    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.0429   -0.5035    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  4  2  1  1  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  1  0  0  0
  7  9  1  0  0  0  0
  9 10  1  1  0  0  0
 10 11  1  0  0  0  0
 12 11  1  6  0  0  0
 12 13  1  0  0  0  0
 13 14  1  6  0  0  0
 13 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  2  0  0  0  0
 17 19  1  0  0  0  0
 19 20  1  0  0  0  0
 19 21  1  0  0  0  0
 19 22  1  0  0  0  0
 13 22  1  0  0  0  0
 22 23  1  6  0  0  0
 23 24  1  0  0  0  0
 24 25  1  0  0  0  0
 12 25  1  0  0  0  0
 25 26  1  6  0  0  0
 25 27  1  0  0  0  0
  9 27  1  0  0  0  0
 27 28  1  1  0  0  0
 27 29  1  0  0  0  0
 29 30  1  0  0  0  0
 30 31  1  0  0  0  0
  4 31  1  0  0  0  0
  7 31  1  0  0  0  0
 31 32  1  6  0  0  0
  4 32  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0237330

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CC(C)[C@@]12CC[C@]3(C)[C@H]4CC[C@@H]5[C@@]6(C)CCC(=O)C(C)(C)[C@@H]6CC[C@@]5(C)[C@]4(C)CC[C@@]13O2

> <INCHI_IDENTIFIER>
InChI=1S/C30H48O2/c1-19(2)29-17-15-28(8)22-10-9-21-25(5)13-12-23(31)24(3,4)20(25)11-14-26(21,6)27(22,7)16-18-30(28,29)32-29/h19-22H,9-18H2,1-8H3/t20-,21+,22-,25-,26+,27+,28+,29-,30-/m0/s1

> <INCHI_KEY>
CMWZPPYBIGXKPR-LPSJIVJRSA-N

> <FORMULA>
C30H48O2

> <MOLECULAR_WEIGHT>
440.712

> <EXACT_MASS>
440.365430786

> <JCHEM_ACCEPTOR_COUNT>
2

> <JCHEM_ATOM_COUNT>
80

> <JCHEM_AVERAGE_POLARIZABILITY>
54.1575982582179

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
0

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(1R,2R,5S,7S,10R,11S,14R,15R,20R)-1,2,10,15,19,19-hexamethyl-7-(propan-2-yl)-6-oxahexacyclo[12.8.0.0^{2,11}.0^{5,7}.0^{5,10}.0^{15,20}]docosan-18-one

> <JCHEM_LOGP>
7.436185229999999

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
6

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA_STRONGEST_ACIDIC>
19.96217040900073

> <JCHEM_PKA_STRONGEST_BASIC>
-4.255952657600525

> <JCHEM_POLAR_SURFACE_AREA>
29.6

> <JCHEM_REFRACTIVITY>
129.6236

> <JCHEM_ROTATABLE_BOND_COUNT>
1

> <JCHEM_RULE_OF_FIVE>
0

> <JCHEM_TRADITIONAL_IUPAC>
(1R,2R,5S,7S,10R,11S,14R,15R,20R)-7-isopropyl-1,2,10,15,19,19-hexamethyl-6-oxahexacyclo[12.8.0.0^{2,11}.0^{5,7}.0^{5,10}.0^{15,20}]docosan-18-one

> <JCHEM_VEBER_RULE>
1

$$$$

HEADER    PROTEIN                                 06-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   06-SEP-22         0                                  
HETATM    1  C   UNK     0      -0.530  -0.837   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       0.188   0.525   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      -0.633   1.828   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       1.727   0.584   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       1.829   2.121   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       3.322   2.499   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       4.143   1.196   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       4.999   2.476   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       5.660   0.934   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       6.646   2.117   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       8.163   1.855   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       8.695   0.410   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0      10.213   0.148   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       9.681   1.593   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0      11.198   1.331   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0      12.716   1.069   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0      13.248  -0.376   0.000  0.00  0.00           C+0
HETATM   18  O   UNK     0      14.765  -0.638   0.000  0.00  0.00           O+0
HETATM   19  C   UNK     0      12.262  -1.559   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0      13.599  -2.325   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0      11.741  -3.008   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0      10.745  -1.297   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0       9.759  -2.481   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0       8.241  -2.219   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0       7.710  -0.773   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0       6.724  -1.957   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0       6.192  -0.511   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0       5.773  -1.993   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0       5.206  -1.695   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0       3.689  -1.433   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0       3.157   0.013   0.000  0.00  0.00           C+0
HETATM   32  O   UNK     0       1.947  -0.940   0.000  0.00  0.00           O+0
CONECT    1    2                                                            
CONECT    2    1    3    4                                                  
CONECT    3    2                                                            
CONECT    4    2    5   31   32                                             
CONECT    5    4    6                                                       
CONECT    6    5    7                                                       
CONECT    7    6    8    9   31                                             
CONECT    8    7                                                            
CONECT    9    7   10   27                                                  
CONECT   10    9   11                                                       
CONECT   11   10   12                                                       
CONECT   12   11   13   25                                                  
CONECT   13   12   14   15   22                                             
CONECT   14   13                                                            
CONECT   15   13   16                                                       
CONECT   16   15   17                                                       
CONECT   17   16   18   19                                                  
CONECT   18   17                                                            
CONECT   19   17   20   21   22                                             
CONECT   20   19                                                            
CONECT   21   19                                                            
CONECT   22   19   13   23                                                  
CONECT   23   22   24                                                       
CONECT   24   23   25                                                       
CONECT   25   24   12   26   27                                             
CONECT   26   25                                                            
CONECT   27   25    9   28   29                                             
CONECT   28   27                                                            
CONECT   29   27   30                                                       
CONECT   30   29   31                                                       
CONECT   31   30    4    7   32                                             
CONECT   32   31    4                                                       
MASTER        0    0    0    0    0    0    0    0   32    0   74    0
END

View in JSmol

Synonyms

Value	Source
17b,21b-Epoxyhopan-3-one	Generator
17Β,21β-epoxyhopan-3-one	Generator

Chemical Formula

C₃₀H₄₈O₂

Average Mass

440.7120 Da

Monoisotopic Mass

440.36543 Da

IUPAC Name

(1R,2R,5S,7S,10R,11S,14R,15R,20R)-1,2,10,15,19,19-hexamethyl-7-(propan-2-yl)-6-oxahexacyclo[12.8.0.0^{2,11}.0^{5,7}.0^{5,10}.0^{15,20}]docosan-18-one

Traditional Name

(1R,2R,5S,7S,10R,11S,14R,15R,20R)-7-isopropyl-1,2,10,15,19,19-hexamethyl-6-oxahexacyclo[12.8.0.0^{2,11}.0^{5,7}.0^{5,10}.0^{15,20}]docosan-18-one

CAS Registry Number

Not Available

SMILES

CC(C)[C@@]12CC[C@]3(C)[C@H]4CC[C@@H]5[C@@]6(C)CCC(=O)C(C)(C)[C@@H]6CC[C@@]5(C)[C@]4(C)CC[C@@]13O2

InChI Identifier

InChI=1S/C30H48O2/c1-19(2)29-17-15-28(8)22-10-9-21-25(5)13-12-23(31)24(3,4)20(25)11-14-26(21,6)27(22,7)16-18-30(28,29)32-29/h19-22H,9-18H2,1-8H3/t20-,21+,22-,25-,26+,27+,28+,29-,30-/m0/s1

InChI Key

CMWZPPYBIGXKPR-LPSJIVJRSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Gentiana scabra	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as hopanoids. These are terpenoids containing hopane skeleton(A'-Neogammacerane), a pentacyclic structure with four cyclohexane rings and one cyclopentane ring (and often, a side chain emerging from C30).

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Prenol lipids

Sub Class

Hopanoids

Direct Parent

Hopanoids

Alternative Parents

Substituents

Hopane-skeleton
Triterpenoid
Naphthopyran
Naphthalene
Oxane
Pyran
Ketone
Cyclic ketone
Dialkyl ether
Oxirane
Ether
Oxacycle
Organoheterocyclic compound
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Carbonyl group
Organooxygen compound
Aliphatic heteropolycyclic compound

Molecular Framework

Aliphatic heteropolycyclic compounds

External Descriptors

epoxide (CHEBI:67825 )
hopanoid (CHEBI:67825 )
cyclic terpene ketone (CHEBI:67825 )

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	7.44	ChemAxon
pKa (Strongest Acidic)	19.96	ChemAxon
pKa (Strongest Basic)	-4.3	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	2	ChemAxon
Hydrogen Donor Count	0	ChemAxon
Polar Surface Area	29.6 Å²	ChemAxon
Rotatable Bond Count	1	ChemAxon
Refractivity	129.62 m³·mol⁻¹	ChemAxon
Polarizability	54.16 Å³	ChemAxon
Number of Rings	6	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	Yes	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

20057114

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

636694

PDB ID

Not Available

ChEBI ID

67825

Good Scents ID

Not Available

References

General References

Gachet MS, Kunert O, Kaiser M, Brun R, Zehl M, Keller W, Munoz RA, Bauer R, Schuehly W: Antiparasitic compounds from Cupania cinerea with activities against Plasmodium falciparum and Trypanosoma brucei rhodesiense. J Nat Prod. 2011 Apr 25;74(4):559-66. doi: 10.1021/np100415m. Epub 2011 Mar 25. [PubMed:21438586 ]
LOTUS database [Link]

Showing NP-Card for 17?,21?-epoxyhopan-3-one (NP0237330)

MOL for NP0237330 (17?,21?-epoxyhopan-3-one)

3D MOL for NP0237330 (17?,21?-epoxyhopan-3-one)

3D SDF for NP0237330 (17?,21?-epoxyhopan-3-one)

3D-SDF for NP0237330 (17?,21?-epoxyhopan-3-one)

PDB for NP0237330 (17?,21?-epoxyhopan-3-one)

3D PDB for NP0237330 (17?,21?-epoxyhopan-3-one)

SMILES for NP0237330 (17?,21?-epoxyhopan-3-one)

INCHI for NP0237330 (17?,21?-epoxyhopan-3-one)

Structure for NP0237330 (17?,21?-epoxyhopan-3-one)

3D Structure for NP0237330 (17?,21?-epoxyhopan-3-one)