NP-MRD: Showing NP-Card for methyl (1s,4ar,7r,7as)-4'-(4-hydroxy-3-methoxybenzoyl)-5'-oxo-1-{[(2s,3r,4s,5r,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4a,7a-dihydro-1h-spiro[cyclopenta[c]pyran-7,2'-furan]-4-carboxylate (NP0236521)

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Record Information

Version

2.0

Created at

2022-09-06 19:26:30 UTC

Updated at

2022-09-06 19:26:30 UTC

NP-MRD ID

NP0236521

Secondary Accession Numbers

None

Natural Product Identification

Common Name

methyl (1s,4ar,7r,7as)-4'-(4-hydroxy-3-methoxybenzoyl)-5'-oxo-1-{[(2s,3r,4s,5r,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4a,7a-dihydro-1h-spiro[cyclopenta[c]pyran-7,2'-furan]-4-carboxylate

Description

Methyl (1S,4aR,7R,7aS)-4'-(4-hydroxy-3-methoxybenzoyl)-5'-oxo-1-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4a,7a-dihydro-1H,5'H-spiro[cyclopenta[c]pyran-7,2'-furan]-4-carboxylate belongs to the class of organic compounds known as iridoid o-glycosides. These are iridoid monoterpenes containing a glycosyl (usually a pyranosyl) moiety linked to the iridoid skeleton. methyl (1s,4ar,7r,7as)-4'-(4-hydroxy-3-methoxybenzoyl)-5'-oxo-1-{[(2s,3r,4s,5r,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4a,7a-dihydro-1h-spiro[cyclopenta[c]pyran-7,2'-furan]-4-carboxylate is found in Morinda citrifolia and Morinda morindoides. Based on a literature review very few articles have been published on methyl (1S,4aR,7R,7aS)-4'-(4-hydroxy-3-methoxybenzoyl)-5'-oxo-1-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4a,7a-dihydro-1H,5'H-spiro[cyclopenta[c]pyran-7,2'-furan]-4-carboxylate.

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652309062221262D          

 41 45  0  0  1  0            999 V2000
    5.8135    4.4652    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.3069    3.8140    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.6176    3.0497    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4348    2.9366    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.1110    2.3985    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.4217    1.6343    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.9151    0.9831    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.0979    1.0962    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.5913    0.4450    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.9020   -0.3192    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.7192   -0.4323    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.0299   -1.1966    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    5.8471   -1.3097    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.1577   -2.0740    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.5233   -1.8478    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.8339   -2.6121    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.7061   -1.7347    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.1995   -2.3859    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.3954   -0.9704    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.5782   -0.8573    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
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    4.2938    2.5117    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.8310    3.1946    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.0385    2.9656    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.0114    2.1410    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.9843    1.3165    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1918    1.0874    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9112    0.3116    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4429   -0.3193    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
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   -1.3374   -0.2683    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2447    0.6525    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7763    1.2834    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
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    1.7290    1.7704    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9045    1.7975    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.2356    2.4216    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  3  5  1  0  0  0  0
  5  6  2  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  1  0  0  0
 10  9  1  6  0  0  0
 10 11  1  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  6  0  0  0
 13 14  1  0  0  0  0
 12 15  1  0  0  0  0
 15 16  1  6  0  0  0
 15 17  1  0  0  0  0
 17 18  1  6  0  0  0
 17 19  1  0  0  0  0
 10 19  1  0  0  0  0
 19 20  1  1  0  0  0
  8 21  1  0  0  0  0
 21 22  1  6  0  0  0
  5 22  1  0  0  0  0
 22 23  1  1  0  0  0
 23 24  2  0  0  0  0
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 21 25  1  0  0  0  0
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 26 27  2  0  0  0  0
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 35 38  2  0  0  0  0
 30 38  1  0  0  0  0
 27 39  1  0  0  0  0
 39 40  2  0  0  0  0
 39 41  1  0  0  0  0
 25 41  1  1  0  0  0
M  END

     RDKit          3D

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   -1.6759    0.2055   -1.4633 O   0  0  0  0  0  0  0  0  0  0  0  0
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M  END


  Mrv1652309062221262D          

 41 45  0  0  1  0            999 V2000
    5.8135    4.4652    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.3069    3.8140    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.6176    3.0497    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
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    4.9151    0.9831    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.0979    1.0962    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.5913    0.4450    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.9020   -0.3192    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.7192   -0.4323    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
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    0.8185   -0.6092    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0064   -0.7542    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5253   -0.1233    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3374   -0.2683    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2447    0.6525    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7763    1.2834    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4958    2.0592    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5675    0.7975    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7290    1.7704    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9045    1.7975    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.2356    2.4216    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  3  5  1  0  0  0  0
  5  6  2  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  1  0  0  0
 10  9  1  6  0  0  0
 10 11  1  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  6  0  0  0
 13 14  1  0  0  0  0
 12 15  1  0  0  0  0
 15 16  1  6  0  0  0
 15 17  1  0  0  0  0
 17 18  1  6  0  0  0
 17 19  1  0  0  0  0
 10 19  1  0  0  0  0
 19 20  1  1  0  0  0
  8 21  1  0  0  0  0
 21 22  1  6  0  0  0
  5 22  1  0  0  0  0
 22 23  1  1  0  0  0
 23 24  2  0  0  0  0
 24 25  1  0  0  0  0
 21 25  1  0  0  0  0
 25 26  1  0  0  0  0
 26 27  2  0  0  0  0
 27 28  1  0  0  0  0
 28 29  2  0  0  0  0
 28 30  1  0  0  0  0
 30 31  2  0  0  0  0
 31 32  1  0  0  0  0
 32 33  2  0  0  0  0
 33 34  1  0  0  0  0
 33 35  1  0  0  0  0
 35 36  1  0  0  0  0
 36 37  1  0  0  0  0
 35 38  2  0  0  0  0
 30 38  1  0  0  0  0
 27 39  1  0  0  0  0
 39 40  2  0  0  0  0
 39 41  1  0  0  0  0
 25 41  1  1  0  0  0
M  END
> <DATABASE_ID>
NP0236521

> <DATABASE_NAME>
NP-MRD

> <SMILES>
COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)[C@H]2[C@H]1C=C[C@]21OC(=O)C(=C1)C(=O)C1=CC=C(O)C(OC)=C1

> <INCHI_IDENTIFIER>
InChI=1S/C27H28O14/c1-36-16-7-11(3-4-15(16)29)19(30)13-8-27(41-24(13)35)6-5-12-14(23(34)37-2)10-38-25(18(12)27)40-26-22(33)21(32)20(31)17(9-28)39-26/h3-8,10,12,17-18,20-22,25-26,28-29,31-33H,9H2,1-2H3/t12-,17+,18+,20-,21-,22+,25-,26-,27+/m0/s1

> <INCHI_KEY>
RIDIXCFHWOHPTF-QPMXNAJYSA-N

> <FORMULA>
C27H28O14

> <MOLECULAR_WEIGHT>
576.507

> <EXACT_MASS>
576.147905582

> <JCHEM_ACCEPTOR_COUNT>
12

> <JCHEM_ATOM_COUNT>
69

> <JCHEM_AVERAGE_POLARIZABILITY>
54.38608218746547

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
5

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
methyl (1S,4aR,7R,7aS)-4'-(4-hydroxy-3-methoxybenzoyl)-5'-oxo-1-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4a,7a-dihydro-1H,5'H-spiro[cyclopenta[c]pyran-7,2'-furan]-4-carboxylate

> <JCHEM_LOGP>
-0.2878464153333329

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
5

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
12.207069247589573

> <JCHEM_PKA_STRONGEST_ACIDIC>
8.220309023591406

> <JCHEM_PKA_STRONGEST_BASIC>
-2.981084760207743

> <JCHEM_POLAR_SURFACE_AREA>
207.73999999999998

> <JCHEM_REFRACTIVITY>
134.8158

> <JCHEM_ROTATABLE_BOND_COUNT>
8

> <JCHEM_RULE_OF_FIVE>
0

> <JCHEM_TRADITIONAL_IUPAC>
methyl (1S,4aR,7R,7aS)-4'-(4-hydroxy-3-methoxybenzoyl)-5'-oxo-1-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4a,7a-dihydro-1H-spiro[cyclopenta[c]pyran-7,2'-furan]-4-carboxylate

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 06-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   06-SEP-22         0                                  
HETATM    1  C   UNK     0      10.852   8.335   0.000  0.00  0.00           C+0
HETATM    2  O   UNK     0       9.906   7.119   0.000  0.00  0.00           O+0
HETATM    3  C   UNK     0      10.486   5.693   0.000  0.00  0.00           C+0
HETATM    4  O   UNK     0      12.012   5.482   0.000  0.00  0.00           O+0
HETATM    5  C   UNK     0       9.541   4.477   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0      10.120   3.051   0.000  0.00  0.00           C+0
HETATM    7  O   UNK     0       9.175   1.835   0.000  0.00  0.00           O+0
HETATM    8  C   UNK     0       7.649   2.046   0.000  0.00  0.00           C+0
HETATM    9  O   UNK     0       6.704   0.831   0.000  0.00  0.00           O+0
HETATM   10  C   UNK     0       7.284  -0.596   0.000  0.00  0.00           C+0
HETATM   11  O   UNK     0       8.809  -0.807   0.000  0.00  0.00           O+0
HETATM   12  C   UNK     0       9.389  -2.234   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0      10.915  -2.445   0.000  0.00  0.00           C+0
HETATM   14  O   UNK     0      11.494  -3.871   0.000  0.00  0.00           O+0
HETATM   15  C   UNK     0       8.443  -3.449   0.000  0.00  0.00           C+0
HETATM   16  O   UNK     0       9.023  -4.876   0.000  0.00  0.00           O+0
HETATM   17  C   UNK     0       6.918  -3.238   0.000  0.00  0.00           C+0
HETATM   18  O   UNK     0       5.972  -4.454   0.000  0.00  0.00           O+0
HETATM   19  C   UNK     0       6.338  -1.811   0.000  0.00  0.00           C+0
HETATM   20  O   UNK     0       4.813  -1.600   0.000  0.00  0.00           O+0
HETATM   21  C   UNK     0       7.070   3.473   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0       8.015   4.688   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0       7.151   5.963   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0       5.672   5.536   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0       5.621   3.997   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0       5.571   2.457   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0       4.091   2.030   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0       3.568   0.582   0.000  0.00  0.00           C+0
HETATM   29  O   UNK     0       4.560  -0.596   0.000  0.00  0.00           O+0
HETATM   30  C   UNK     0       2.052   0.311   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0       1.528  -1.137   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0       0.012  -1.408   0.000  0.00  0.00           C+0
HETATM   33  C   UNK     0      -0.980  -0.230   0.000  0.00  0.00           C+0
HETATM   34  O   UNK     0      -2.497  -0.501   0.000  0.00  0.00           O+0
HETATM   35  C   UNK     0      -0.457   1.218   0.000  0.00  0.00           C+0
HETATM   36  O   UNK     0      -1.449   2.396   0.000  0.00  0.00           O+0
HETATM   37  C   UNK     0      -0.925   3.844   0.000  0.00  0.00           C+0
HETATM   38  C   UNK     0       1.059   1.489   0.000  0.00  0.00           C+0
HETATM   39  C   UNK     0       3.228   3.305   0.000  0.00  0.00           C+0
HETATM   40  O   UNK     0       1.688   3.355   0.000  0.00  0.00           O+0
HETATM   41  O   UNK     0       4.173   4.520   0.000  0.00  0.00           O+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4    5                                                  
CONECT    4    3                                                            
CONECT    5    3    6   22                                                  
CONECT    6    5    7                                                       
CONECT    7    6    8                                                       
CONECT    8    7    9   21                                                  
CONECT    9    8   10                                                       
CONECT   10    9   11   19                                                  
CONECT   11   10   12                                                       
CONECT   12   11   13   15                                                  
CONECT   13   12   14                                                       
CONECT   14   13                                                            
CONECT   15   12   16   17                                                  
CONECT   16   15                                                            
CONECT   17   15   18   19                                                  
CONECT   18   17                                                            
CONECT   19   17   10   20                                                  
CONECT   20   19                                                            
CONECT   21    8   22   25                                                  
CONECT   22   21    5   23                                                  
CONECT   23   22   24                                                       
CONECT   24   23   25                                                       
CONECT   25   24   21   26   41                                             
CONECT   26   25   27                                                       
CONECT   27   26   28   39                                                  
CONECT   28   27   29   30                                                  
CONECT   29   28                                                            
CONECT   30   28   31   38                                                  
CONECT   31   30   32                                                       
CONECT   32   31   33                                                       
CONECT   33   32   34   35                                                  
CONECT   34   33                                                            
CONECT   35   33   36   38                                                  
CONECT   36   35   37                                                       
CONECT   37   36                                                            
CONECT   38   35   30                                                       
CONECT   39   27   40   41                                                  
CONECT   40   39                                                            
CONECT   41   39   25                                                       
MASTER        0    0    0    0    0    0    0    0   41    0   90    0
END

View in JSmol

Synonyms

Value	Source
Methyl (1S,4ar,7R,7as)-4'-(4-hydroxy-3-methoxybenzoyl)-5'-oxo-1-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4a,7a-dihydro-1H,5'H-spiro[cyclopenta[c]pyran-7,2'-furan]-4-carboxylic acid	Generator

Chemical Formula

C₂₇H₂₈O₁₄

Average Mass

576.5070 Da

Monoisotopic Mass

576.14791 Da

IUPAC Name

Not Available

Traditional Name

Not Available

CAS Registry Number

Not Available

SMILES

COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)[C@H]2[C@H]1C=C[C@]21OC(=O)C(=C1)C(=O)C1=CC=C(O)C(OC)=C1

InChI Identifier

InChI=1S/C27H28O14/c1-36-16-7-11(3-4-15(16)29)19(30)13-8-27(41-24(13)35)6-5-12-14(23(34)37-2)10-38-25(18(12)27)40-26-22(33)21(32)20(31)17(9-28)39-26/h3-8,10,12,17-18,20-22,25-26,28-29,31-33H,9H2,1-2H3/t12-,17+,18+,20-,21-,22+,25-,26-,27+/m0/s1

InChI Key

RIDIXCFHWOHPTF-QPMXNAJYSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Morinda citrifolia	LOTUS Database	35616633
Morinda morindoides	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as iridoid o-glycosides. These are iridoid monoterpenes containing a glycosyl (usually a pyranosyl) moiety linked to the iridoid skeleton.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Prenol lipids

Sub Class

Terpene glycosides

Direct Parent

Iridoid O-glycosides

Alternative Parents

Substituents

Iridoid o-glycoside
Terpene lactone
Hexose monosaccharide
O-glycosyl compound
Iridoid-skeleton
Glycosyl compound
Monoterpenoid
Methoxyphenol
Bicyclic monoterpenoid
Aromatic monoterpenoid
Phenoxy compound
Methoxybenzene
Aryl ketone
Phenol ether
Benzoyl
Anisole
1-hydroxy-2-unsubstituted benzenoid
Phenol
Alkyl aryl ether
Benzenoid
Oxane
Monosaccharide
Dicarboxylic acid or derivatives
2-furanone
Monocyclic benzene moiety
Vinylogous ester
Alpha,beta-unsaturated carboxylic ester
Enoate ester
Methyl ester
Dihydrofuran
Secondary alcohol
Lactone
Ketone
Carboxylic acid ester
Oxacycle
Organoheterocyclic compound
Polyol
Ether
Carboxylic acid derivative
Acetal
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Primary alcohol
Organooxygen compound
Carbonyl group
Alcohol
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

163091609

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for methyl (1s,4ar,7r,7as)-4'-(4-hydroxy-3-methoxybenzoyl)-5'-oxo-1-{[(2s,3r,4s,5r,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4a,7a-dihydro-1h-spiro[cyclopenta[c]pyran-7,2'-furan]-4-carboxylate (NP0236521)

MOL for NP0236521 (methyl (1s,4ar,7r,7as)-4'-(4-hydroxy-3-methoxybenzoyl)-5'-oxo-1-{[(2s,3r,4s,5r,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4a,7a-dihydro-1h-spiro[cyclopenta[c]pyran-7,2'-furan]-4-carboxylate)

3D MOL for NP0236521 (methyl (1s,4ar,7r,7as)-4'-(4-hydroxy-3-methoxybenzoyl)-5'-oxo-1-{[(2s,3r,4s,5r,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4a,7a-dihydro-1h-spiro[cyclopenta[c]pyran-7,2'-furan]-4-carboxylate)

3D SDF for NP0236521 (methyl (1s,4ar,7r,7as)-4'-(4-hydroxy-3-methoxybenzoyl)-5'-oxo-1-{[(2s,3r,4s,5r,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4a,7a-dihydro-1h-spiro[cyclopenta[c]pyran-7,2'-furan]-4-carboxylate)

3D-SDF for NP0236521 (methyl (1s,4ar,7r,7as)-4'-(4-hydroxy-3-methoxybenzoyl)-5'-oxo-1-{[(2s,3r,4s,5r,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4a,7a-dihydro-1h-spiro[cyclopenta[c]pyran-7,2'-furan]-4-carboxylate)

PDB for NP0236521 (methyl (1s,4ar,7r,7as)-4'-(4-hydroxy-3-methoxybenzoyl)-5'-oxo-1-{[(2s,3r,4s,5r,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4a,7a-dihydro-1h-spiro[cyclopenta[c]pyran-7,2'-furan]-4-carboxylate)

3D PDB for NP0236521 (methyl (1s,4ar,7r,7as)-4'-(4-hydroxy-3-methoxybenzoyl)-5'-oxo-1-{[(2s,3r,4s,5r,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4a,7a-dihydro-1h-spiro[cyclopenta[c]pyran-7,2'-furan]-4-carboxylate)

SMILES for NP0236521 (methyl (1s,4ar,7r,7as)-4'-(4-hydroxy-3-methoxybenzoyl)-5'-oxo-1-{[(2s,3r,4s,5r,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4a,7a-dihydro-1h-spiro[cyclopenta[c]pyran-7,2'-furan]-4-carboxylate)

INCHI for NP0236521 (methyl (1s,4ar,7r,7as)-4'-(4-hydroxy-3-methoxybenzoyl)-5'-oxo-1-{[(2s,3r,4s,5r,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4a,7a-dihydro-1h-spiro[cyclopenta[c]pyran-7,2'-furan]-4-carboxylate)

Structure for NP0236521 (methyl (1s,4ar,7r,7as)-4'-(4-hydroxy-3-methoxybenzoyl)-5'-oxo-1-{[(2s,3r,4s,5r,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4a,7a-dihydro-1h-spiro[cyclopenta[c]pyran-7,2'-furan]-4-carboxylate)

3D Structure for NP0236521 (methyl (1s,4ar,7r,7as)-4'-(4-hydroxy-3-methoxybenzoyl)-5'-oxo-1-{[(2s,3r,4s,5r,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4a,7a-dihydro-1h-spiro[cyclopenta[c]pyran-7,2'-furan]-4-carboxylate)