NP-MRD: Showing NP-Card for (2s,3r,4s,5s,6r)-2-{[(1s,4ar,6s,7r,7as)-6-hydroxy-7-methyl-1h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyran-1-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl (2e)-3-(3,4-dimethoxyphenyl)prop-2-enoate (NP0232113)

Jump To Section:

Identification Spectra BioTaxonomy ChemoTaxonomy Physical properties Links References XML

Record Information

Version

2.0

Created at

2022-09-06 13:14:12 UTC

Updated at

2022-09-06 13:14:12 UTC

NP-MRD ID

NP0232113

Secondary Accession Numbers

None

Natural Product Identification

Common Name

(2s,3r,4s,5s,6r)-2-{[(1s,4ar,6s,7r,7as)-6-hydroxy-7-methyl-1h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyran-1-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl (2e)-3-(3,4-dimethoxyphenyl)prop-2-enoate

Description

Alboside II belongs to the class of organic compounds known as iridoid o-glycosides. These are iridoid monoterpenes containing a glycosyl (usually a pyranosyl) moiety linked to the iridoid skeleton. (2s,3r,4s,5s,6r)-2-{[(1s,4ar,6s,7r,7as)-6-hydroxy-7-methyl-1h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyran-1-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl (2e)-3-(3,4-dimethoxyphenyl)prop-2-enoate is found in Chiococca alba. Based on a literature review very few articles have been published on Alboside II.

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652309062215142D          

 37 40  0  0  1  0            999 V2000
    5.4223   -4.1250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7079   -3.7125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.7079   -2.8875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9934   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9934   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7079   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7079   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.4223    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.4223    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.1368    1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.7079    1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.7079    2.0625    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.9934    2.4750    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.2789    2.0625    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.2789    1.2375    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.9934    0.8250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.9934    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2789   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5645    0.0000    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.7798   -0.2549    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2949    0.4125    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.4699    0.4125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.7798    1.0799    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.5249    1.8646    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5645    0.8250    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.9934    3.3000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.7079    3.7125    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.7079    4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.4223    4.9500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.4223    3.3000    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    6.1368    3.7125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.4223    2.4750    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    6.1368    2.0625    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.4223   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.4223   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.1368   -2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.1368   -3.7125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  4  5  1  0  0  0  0
  5  6  2  0  0  0  0
  6  7  1  0  0  0  0
  7  8  2  0  0  0  0
  8  9  1  0  0  0  0
  9 10  2  0  0  0  0
  9 11  1  0  0  0  0
 12 11  1  1  0  0  0
 12 13  1  0  0  0  0
 13 14  1  6  0  0  0
 15 14  1  6  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  2  0  0  0  0
 18 19  1  0  0  0  0
 19 20  1  1  0  0  0
 20 21  1  0  0  0  0
 21 22  1  6  0  0  0
 21 23  1  0  0  0  0
 23 24  1  6  0  0  0
 25 23  1  1  0  0  0
 15 25  1  0  0  0  0
 19 25  1  0  0  0  0
 13 26  1  0  0  0  0
 26 27  1  0  0  0  0
 27 28  1  6  0  0  0
 28 29  1  0  0  0  0
 27 30  1  0  0  0  0
 30 31  1  1  0  0  0
 30 32  1  0  0  0  0
 12 32  1  0  0  0  0
 32 33  1  6  0  0  0
  6 34  1  0  0  0  0
 34 35  2  0  0  0  0
  3 35  1  0  0  0  0
 35 36  1  0  0  0  0
 36 37  1  0  0  0  0
M  END

     RDKit          3D

 71 74  0  0  0  0  0  0  0  0999 V2000
    8.0030   -0.2826   -4.4515 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.8111   -1.0132   -4.4034 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.9073   -0.7918   -3.3972 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.1628    0.1417   -2.4367 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2563    0.3723   -1.4168 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0983   -0.3437   -1.3772 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1144   -0.1626   -0.3562 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2760    0.7140    0.6122 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2140    0.8497    1.6395 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3206    1.6675    2.5788 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.0723    0.0743    1.5885 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.0730    0.2001    2.5536 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.2954    0.4848    1.9627 C   0  0  2  0  0  0  0  0  0  0  0  0
   -1.2585    1.2577    0.8221 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7181    0.6336   -0.3039 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.7339    0.4876   -1.3073 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0624    0.1330   -2.6091 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2316    0.4736   -3.0490 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2020    1.2042   -2.2443 C   0  0  1  0  0  0  0  0  0  0  0  0
   -4.5574    0.4681   -2.3096 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.2808    1.0309   -1.0829 C   0  0  2  0  0  0  0  0  0  0  0  0
   -5.6242    2.3395   -1.3918 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1762    1.0093   -0.0696 C   0  0  2  0  0  0  0  0  0  0  0  0
   -4.4571    1.9880    1.0664 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9365    1.3740   -0.8118 C   0  0  1  0  0  0  0  0  0  0  0  0
   -2.0788    0.9514    2.9827 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3409   -0.0730    3.8547 C   0  0  2  0  0  0  0  0  0  0  0  0
   -3.2079    0.3806    5.0243 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4255    0.8683    4.6191 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1523   -0.7769    4.4076 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.6017   -2.0233    4.8997 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1028   -1.0917    3.3671 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.0584   -1.4631    3.9996 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.8470   -1.2987   -2.3686 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7377   -1.5389   -3.3877 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4641   -2.4777   -4.3408 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.2596   -3.2090   -4.2851 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.8142    0.8254   -4.3567 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.6746   -0.5968   -3.6325 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.4987   -0.5071   -5.4218 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.0780    0.7374   -2.4323 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.5065    1.1336   -0.6659 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.1802   -0.7359   -0.3210 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.1276    1.3403    0.7103 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.3165    0.9745    3.3250 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7186   -0.5215    1.6684 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0423   -0.3911   -0.0389 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3007   -0.4112   -3.1659 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5077    0.2062   -4.0616 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3764    2.2203   -2.7328 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4029   -0.5951   -2.1314 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.0631    0.7335   -3.2496 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1494    0.4083   -0.8133 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.5980    2.4495   -1.5413 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1421   -0.0321    0.3305 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5101    2.5455    1.2316 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.7531    1.4087    1.9390 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.2897    2.6238    0.7480 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7892    2.4881   -0.6201 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9686   -0.8204    3.2960 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6832    1.2224    5.5575 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2906   -0.4321    5.7666 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1109    0.1551    4.5977 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6468   -0.2581    5.2328 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8824   -2.6111    4.1558 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4691   -1.8764    2.6618 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.5233   -2.1270    3.4107 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.9088   -1.8483   -2.2995 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.3641   -4.0645   -5.0103 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.0491   -3.6296   -3.2826 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.4215   -2.5720   -4.6707 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  2  0
  4  5  1  0
  5  6  2  0
  6  7  1  0
  7  8  2  0
  8  9  1  0
  9 10  2  0
  9 11  1  0
 11 12  1  0
 12 13  1  0
 13 14  1  0
 14 15  1  0
 15 16  1  0
 16 17  1  0
 17 18  2  0
 18 19  1  0
 19 20  1  0
 20 21  1  0
 21 22  1  0
 21 23  1  0
 23 24  1  0
 23 25  1  0
 13 26  1  0
 26 27  1  0
 27 28  1  0
 28 29  1  0
 27 30  1  0
 30 31  1  0
 30 32  1  0
 32 33  1  0
  6 34  1  0
 34 35  2  0
 35 36  1  0
 36 37  1  0
 35  3  1  0
 32 12  1  0
 25 15  1  0
 25 19  1  0
  1 38  1  0
  1 39  1  0
  1 40  1  0
  4 41  1  0
  5 42  1  0
  7 43  1  0
  8 44  1  0
 12 45  1  1
 13 46  1  6
 15 47  1  1
 17 48  1  0
 18 49  1  0
 19 50  1  6
 20 51  1  0
 20 52  1  0
 21 53  1  1
 22 54  1  0
 23 55  1  1
 24 56  1  0
 24 57  1  0
 24 58  1  0
 25 59  1  6
 27 60  1  6
 28 61  1  0
 28 62  1  0
 29 63  1  0
 30 64  1  1
 31 65  1  0
 32 66  1  6
 33 67  1  0
 34 68  1  0
 37 69  1  0
 37 70  1  0
 37 71  1  0
M  END


  Mrv1652309062215142D          

 37 40  0  0  1  0            999 V2000
    5.4223   -4.1250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7079   -3.7125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.7079   -2.8875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9934   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9934   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7079   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7079   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.4223    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.4223    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.1368    1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.7079    1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.7079    2.0625    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.9934    2.4750    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.2789    2.0625    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.2789    1.2375    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.9934    0.8250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.9934    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2789   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5645    0.0000    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.7798   -0.2549    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2949    0.4125    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.4699    0.4125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.7798    1.0799    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.5249    1.8646    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5645    0.8250    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.9934    3.3000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.7079    3.7125    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.7079    4.5375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.4223    4.9500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.4223    3.3000    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    6.1368    3.7125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.4223    2.4750    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    6.1368    2.0625    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.4223   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.4223   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.1368   -2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.1368   -3.7125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  4  5  1  0  0  0  0
  5  6  2  0  0  0  0
  6  7  1  0  0  0  0
  7  8  2  0  0  0  0
  8  9  1  0  0  0  0
  9 10  2  0  0  0  0
  9 11  1  0  0  0  0
 12 11  1  1  0  0  0
 12 13  1  0  0  0  0
 13 14  1  6  0  0  0
 15 14  1  6  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  2  0  0  0  0
 18 19  1  0  0  0  0
 19 20  1  1  0  0  0
 20 21  1  0  0  0  0
 21 22  1  6  0  0  0
 21 23  1  0  0  0  0
 23 24  1  6  0  0  0
 25 23  1  1  0  0  0
 15 25  1  0  0  0  0
 19 25  1  0  0  0  0
 13 26  1  0  0  0  0
 26 27  1  0  0  0  0
 27 28  1  6  0  0  0
 28 29  1  0  0  0  0
 27 30  1  0  0  0  0
 30 31  1  1  0  0  0
 30 32  1  0  0  0  0
 12 32  1  0  0  0  0
 32 33  1  6  0  0  0
  6 34  1  0  0  0  0
 34 35  2  0  0  0  0
  3 35  1  0  0  0  0
 35 36  1  0  0  0  0
 36 37  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0232113

> <DATABASE_NAME>
NP-MRD

> <SMILES>
COC1=CC=C(\C=C\C(=O)O[C@H]2[C@H](O[C@@H]3OC=C[C@H]4C[C@H](O)[C@H](C)[C@@H]34)O[C@H](CO)[C@@H](O)[C@@H]2O)C=C1OC

> <INCHI_IDENTIFIER>
InChI=1S/C26H34O11/c1-13-16(28)11-15-8-9-34-25(21(13)15)37-26-24(23(31)22(30)19(12-27)35-26)36-20(29)7-5-14-4-6-17(32-2)18(10-14)33-3/h4-10,13,15-16,19,21-28,30-31H,11-12H2,1-3H3/b7-5+/t13-,15-,16-,19+,21+,22+,23-,24+,25-,26-/m0/s1

> <INCHI_KEY>
ZQSWKWQNHBNVMV-JJOJVLBSSA-N

> <FORMULA>
C26H34O11

> <MOLECULAR_WEIGHT>
522.547

> <EXACT_MASS>
522.210111915

> <JCHEM_ACCEPTOR_COUNT>
10

> <JCHEM_ATOM_COUNT>
71

> <JCHEM_AVERAGE_POLARIZABILITY>
54.33432903167022

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
4

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(2S,3R,4S,5S,6R)-2-{[(1S,4aR,6S,7R,7aS)-6-hydroxy-7-methyl-1H,4aH,5H,6H,7H,7aH-cyclopenta[c]pyran-1-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl (2E)-3-(3,4-dimethoxyphenyl)prop-2-enoate

> <JCHEM_LOGP>
1.0671214623333318

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
4

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
13.9687372759294

> <JCHEM_PKA_STRONGEST_ACIDIC>
12.692653102995457

> <JCHEM_PKA_STRONGEST_BASIC>
-2.8334252515697074

> <JCHEM_POLAR_SURFACE_AREA>
153.37

> <JCHEM_REFRACTIVITY>
129.20020000000002

> <JCHEM_ROTATABLE_BOND_COUNT>
9

> <JCHEM_RULE_OF_FIVE>
0

> <JCHEM_TRADITIONAL_IUPAC>
(2S,3R,4S,5S,6R)-2-{[(1S,4aR,6S,7R,7aS)-6-hydroxy-7-methyl-1H,4aH,5H,6H,7H,7aH-cyclopenta[c]pyran-1-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl (2E)-3-(3,4-dimethoxyphenyl)prop-2-enoate

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 06-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   06-SEP-22         0                                  
HETATM    1  C   UNK     0      10.122  -7.700   0.000  0.00  0.00           C+0
HETATM    2  O   UNK     0       8.788  -6.930   0.000  0.00  0.00           O+0
HETATM    3  C   UNK     0       8.788  -5.390   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       7.454  -4.620   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       7.454  -3.080   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       8.788  -2.310   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       8.788  -0.770   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0      10.122   0.000   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0      10.122   1.540   0.000  0.00  0.00           C+0
HETATM   10  O   UNK     0      11.455   2.310   0.000  0.00  0.00           O+0
HETATM   11  O   UNK     0       8.788   2.310   0.000  0.00  0.00           O+0
HETATM   12  C   UNK     0       8.788   3.850   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       7.454   4.620   0.000  0.00  0.00           C+0
HETATM   14  O   UNK     0       6.121   3.850   0.000  0.00  0.00           O+0
HETATM   15  C   UNK     0       6.121   2.310   0.000  0.00  0.00           C+0
HETATM   16  O   UNK     0       7.454   1.540   0.000  0.00  0.00           O+0
HETATM   17  C   UNK     0       7.454   0.000   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       6.121  -0.770   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       4.787   0.000   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0       3.322  -0.476   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0       2.417   0.770   0.000  0.00  0.00           C+0
HETATM   22  O   UNK     0       0.877   0.770   0.000  0.00  0.00           O+0
HETATM   23  C   UNK     0       3.322   2.016   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0       2.846   3.481   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0       4.787   1.540   0.000  0.00  0.00           C+0
HETATM   26  O   UNK     0       7.454   6.160   0.000  0.00  0.00           O+0
HETATM   27  C   UNK     0       8.788   6.930   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0       8.788   8.470   0.000  0.00  0.00           C+0
HETATM   29  O   UNK     0      10.122   9.240   0.000  0.00  0.00           O+0
HETATM   30  C   UNK     0      10.122   6.160   0.000  0.00  0.00           C+0
HETATM   31  O   UNK     0      11.455   6.930   0.000  0.00  0.00           O+0
HETATM   32  C   UNK     0      10.122   4.620   0.000  0.00  0.00           C+0
HETATM   33  O   UNK     0      11.455   3.850   0.000  0.00  0.00           O+0
HETATM   34  C   UNK     0      10.122  -3.080   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0      10.122  -4.620   0.000  0.00  0.00           C+0
HETATM   36  O   UNK     0      11.455  -5.390   0.000  0.00  0.00           O+0
HETATM   37  C   UNK     0      11.455  -6.930   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4   35                                                  
CONECT    4    3    5                                                       
CONECT    5    4    6                                                       
CONECT    6    5    7   34                                                  
CONECT    7    6    8                                                       
CONECT    8    7    9                                                       
CONECT    9    8   10   11                                                  
CONECT   10    9                                                            
CONECT   11    9   12                                                       
CONECT   12   11   13   32                                                  
CONECT   13   12   14   26                                                  
CONECT   14   13   15                                                       
CONECT   15   14   16   25                                                  
CONECT   16   15   17                                                       
CONECT   17   16   18                                                       
CONECT   18   17   19                                                       
CONECT   19   18   20   25                                                  
CONECT   20   19   21                                                       
CONECT   21   20   22   23                                                  
CONECT   22   21                                                            
CONECT   23   21   24   25                                                  
CONECT   24   23                                                            
CONECT   25   23   15   19                                                  
CONECT   26   13   27                                                       
CONECT   27   26   28   30                                                  
CONECT   28   27   29                                                       
CONECT   29   28                                                            
CONECT   30   27   31   32                                                  
CONECT   31   30                                                            
CONECT   32   30   12   33                                                  
CONECT   33   32                                                            
CONECT   34    6   35                                                       
CONECT   35   34    3   36                                                  
CONECT   36   35   37                                                       
CONECT   37   36                                                            
MASTER        0    0    0    0    0    0    0    0   37    0   80    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₂₆H₃₄O₁₁

Average Mass

522.5470 Da

Monoisotopic Mass

522.21011 Da

IUPAC Name

(2S,3R,4S,5S,6R)-2-{[(1S,4aR,6S,7R,7aS)-6-hydroxy-7-methyl-1H,4aH,5H,6H,7H,7aH-cyclopenta[c]pyran-1-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl (2E)-3-(3,4-dimethoxyphenyl)prop-2-enoate

Traditional Name

(2S,3R,4S,5S,6R)-2-{[(1S,4aR,6S,7R,7aS)-6-hydroxy-7-methyl-1H,4aH,5H,6H,7H,7aH-cyclopenta[c]pyran-1-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl (2E)-3-(3,4-dimethoxyphenyl)prop-2-enoate

CAS Registry Number

Not Available

SMILES

COC1=CC=C(\C=C\C(=O)O[C@H]2[C@H](O[C@@H]3OC=C[C@H]4C[C@H](O)[C@H](C)[C@@H]34)O[C@H](CO)[C@@H](O)[C@@H]2O)C=C1OC

InChI Identifier

InChI=1S/C26H34O11/c1-13-16(28)11-15-8-9-34-25(21(13)15)37-26-24(23(31)22(30)19(12-27)35-26)36-20(29)7-5-14-4-6-17(32-2)18(10-14)33-3/h4-10,13,15-16,19,21-28,30-31H,11-12H2,1-3H3/b7-5+/t13-,15-,16-,19+,21+,22+,23-,24+,25-,26-/m0/s1

InChI Key

ZQSWKWQNHBNVMV-JJOJVLBSSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Chiococca alba	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as iridoid o-glycosides. These are iridoid monoterpenes containing a glycosyl (usually a pyranosyl) moiety linked to the iridoid skeleton.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Prenol lipids

Sub Class

Terpene glycosides

Direct Parent

Iridoid O-glycosides

Alternative Parents

Substituents

Iridoid o-glycoside
Cinnamic acid ester
Hexose monosaccharide
Coumaric acid or derivatives
Cinnamic acid or derivatives
O-glycosyl compound
Iridoid-skeleton
Glycosyl compound
O-dimethoxybenzene
Dimethoxybenzene
Monoterpenoid
Bicyclic monoterpenoid
Aromatic monoterpenoid
Phenoxy compound
Methoxybenzene
Styrene
Phenol ether
Anisole
Fatty acid ester
Alkyl aryl ether
Fatty acyl
Benzenoid
Oxane
Monosaccharide
Monocyclic benzene moiety
Alpha,beta-unsaturated carboxylic ester
Enoate ester
Cyclic alcohol
Secondary alcohol
Carboxylic acid ester
Oxacycle
Organoheterocyclic compound
Monocarboxylic acid or derivatives
Ether
Carboxylic acid derivative
Acetal
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Primary alcohol
Organooxygen compound
Carbonyl group
Alcohol
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	1.07	ChemAxon
pKa (Strongest Acidic)	12.69	ChemAxon
pKa (Strongest Basic)	-2.8	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	10	ChemAxon
Hydrogen Donor Count	4	ChemAxon
Polar Surface Area	153.37 Å²	ChemAxon
Rotatable Bond Count	9	ChemAxon
Refractivity	129.2 m³·mol⁻¹	ChemAxon
Polarizability	54.33 Å³	ChemAxon
Number of Rings	4	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	Yes	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

C00038402

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

100982916

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for (2s,3r,4s,5s,6r)-2-{[(1s,4ar,6s,7r,7as)-6-hydroxy-7-methyl-1h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyran-1-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl (2e)-3-(3,4-dimethoxyphenyl)prop-2-enoate (NP0232113)

MOL for NP0232113 ((2s,3r,4s,5s,6r)-2-{[(1s,4ar,6s,7r,7as)-6-hydroxy-7-methyl-1h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyran-1-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl (2e)-3-(3,4-dimethoxyphenyl)prop-2-enoate)

3D MOL for NP0232113 ((2s,3r,4s,5s,6r)-2-{[(1s,4ar,6s,7r,7as)-6-hydroxy-7-methyl-1h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyran-1-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl (2e)-3-(3,4-dimethoxyphenyl)prop-2-enoate)

3D SDF for NP0232113 ((2s,3r,4s,5s,6r)-2-{[(1s,4ar,6s,7r,7as)-6-hydroxy-7-methyl-1h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyran-1-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl (2e)-3-(3,4-dimethoxyphenyl)prop-2-enoate)

3D-SDF for NP0232113 ((2s,3r,4s,5s,6r)-2-{[(1s,4ar,6s,7r,7as)-6-hydroxy-7-methyl-1h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyran-1-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl (2e)-3-(3,4-dimethoxyphenyl)prop-2-enoate)

PDB for NP0232113 ((2s,3r,4s,5s,6r)-2-{[(1s,4ar,6s,7r,7as)-6-hydroxy-7-methyl-1h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyran-1-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl (2e)-3-(3,4-dimethoxyphenyl)prop-2-enoate)

3D PDB for NP0232113 ((2s,3r,4s,5s,6r)-2-{[(1s,4ar,6s,7r,7as)-6-hydroxy-7-methyl-1h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyran-1-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl (2e)-3-(3,4-dimethoxyphenyl)prop-2-enoate)

SMILES for NP0232113 ((2s,3r,4s,5s,6r)-2-{[(1s,4ar,6s,7r,7as)-6-hydroxy-7-methyl-1h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyran-1-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl (2e)-3-(3,4-dimethoxyphenyl)prop-2-enoate)

INCHI for NP0232113 ((2s,3r,4s,5s,6r)-2-{[(1s,4ar,6s,7r,7as)-6-hydroxy-7-methyl-1h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyran-1-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl (2e)-3-(3,4-dimethoxyphenyl)prop-2-enoate)

Structure for NP0232113 ((2s,3r,4s,5s,6r)-2-{[(1s,4ar,6s,7r,7as)-6-hydroxy-7-methyl-1h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyran-1-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl (2e)-3-(3,4-dimethoxyphenyl)prop-2-enoate)

3D Structure for NP0232113 ((2s,3r,4s,5s,6r)-2-{[(1s,4ar,6s,7r,7as)-6-hydroxy-7-methyl-1h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyran-1-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl (2e)-3-(3,4-dimethoxyphenyl)prop-2-enoate)