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Showing NP-Card for (2r)-8-benzoyl-2-methyl-2-(4-methylpent-3-en-1-yl)chromene-5,7-diol (NP0225345)

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Record Information
Version2.0
Created at2022-09-06 04:02:17 UTC
Updated at2022-09-06 04:02:17 UTC
NP-MRD IDNP0225345
Secondary Accession NumbersNone
Natural Product Identification
Common Name(2r)-8-benzoyl-2-methyl-2-(4-methylpent-3-en-1-yl)chromene-5,7-diol
Description8-Benzoyl-2beta-methyl-2-(4-methyl-3-pentenyl)-2H-1-benzopyran-5,7-diol belongs to the class of organic compounds known as benzophenones. These are organic compounds containing a ketone attached to two phenyl groups. (2r)-8-benzoyl-2-methyl-2-(4-methylpent-3-en-1-yl)chromene-5,7-diol is found in Clusia multiflora. Based on a literature review very few articles have been published on 8-Benzoyl-2beta-methyl-2-(4-methyl-3-pentenyl)-2H-1-benzopyran-5,7-diol.
Structure
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MOLSDFPDBSMILESInChI

MOL for NP0225345 ((2r)-8-benzoyl-2-methyl-2-(4-methylpent-3-en-1-yl)chromene-5,7-diol)


  Mrv1652309062206022D          

 27 29  0  0  1  0            999 V2000
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   -1.7229   -0.8077    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1926   -0.1757    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4408   -1.5830    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6283   -1.7262    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0980   -1.0942    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -1.2375    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.4323   -2.0127    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.8250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
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    4.2868   -1.6500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
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    2.1434   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -1.6500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  2  4  2  0  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  7  6  1  6  0  0  0
  7  8  1  1  0  0  0
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 10 11  1  0  0  0  0
 11 12  2  0  0  0  0
 12 13  1  0  0  0  0
 12 14  1  0  0  0  0
 14 15  2  0  0  0  0
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 18 20  1  0  0  0  0
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 11 26  1  0  0  0  0
 26 27  1  0  0  0  0
  7 27  1  0  0  0  0
M  END
Download

3D MOL for NP0225345 ((2r)-8-benzoyl-2-methyl-2-(4-methylpent-3-en-1-yl)chromene-5,7-diol)

Download
3D SDF for NP0225345 ((2r)-8-benzoyl-2-methyl-2-(4-methylpent-3-en-1-yl)chromene-5,7-diol)

  Mrv1652309062206022D          

 27 29  0  0  1  0            999 V2000
   -2.5354   -0.6645    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7229   -0.8077    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1926   -0.1757    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4408   -1.5830    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6283   -1.7262    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0980   -1.0942    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -1.2375    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.4323   -2.0127    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.8250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868   -1.6500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -2.8875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -3.7125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -4.1250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -3.7125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -2.8875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -1.6500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  2  4  2  0  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  7  6  1  6  0  0  0
  7  8  1  1  0  0  0
  7  9  1  0  0  0  0
  9 10  2  0  0  0  0
 10 11  1  0  0  0  0
 11 12  2  0  0  0  0
 12 13  1  0  0  0  0
 12 14  1  0  0  0  0
 14 15  2  0  0  0  0
 15 16  1  0  0  0  0
 15 17  1  0  0  0  0
 17 18  1  0  0  0  0
 18 19  2  0  0  0  0
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 21 22  1  0  0  0  0
 22 23  2  0  0  0  0
 23 24  1  0  0  0  0
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 20 25  1  0  0  0  0
 17 26  2  0  0  0  0
 11 26  1  0  0  0  0
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  7 27  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0225345

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CC(C)=CCC[C@@]1(C)OC2=C(C(=O)C3=CC=CC=C3)C(O)=CC(O)=C2C=C1

> <INCHI_IDENTIFIER>
InChI=1S/C23H24O4/c1-15(2)8-7-12-23(3)13-11-17-18(24)14-19(25)20(22(17)27-23)21(26)16-9-5-4-6-10-16/h4-6,8-11,13-14,24-25H,7,12H2,1-3H3/t23-/m1/s1

> <INCHI_KEY>
VHBOXYDOVCZHPH-HSZRJFAPSA-N

> <FORMULA>
C23H24O4

> <MOLECULAR_WEIGHT>
364.441

> <EXACT_MASS>
364.167459253

> <JCHEM_ACCEPTOR_COUNT>
4

> <JCHEM_ATOM_COUNT>
51

> <JCHEM_AVERAGE_POLARIZABILITY>
40.39604304957406

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
2

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(2R)-8-benzoyl-2-methyl-2-(4-methylpent-3-en-1-yl)-2H-chromene-5,7-diol

> <JCHEM_LOGP>
6.113759617000001

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
3

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
8.65804151631101

> <JCHEM_PKA_STRONGEST_ACIDIC>
7.312866213445777

> <JCHEM_PKA_STRONGEST_BASIC>
-4.975952057863301

> <JCHEM_POLAR_SURFACE_AREA>
66.76

> <JCHEM_REFRACTIVITY>
108.7143

> <JCHEM_ROTATABLE_BOND_COUNT>
5

> <JCHEM_RULE_OF_FIVE>
0

> <JCHEM_TRADITIONAL_IUPAC>
(2R)-8-benzoyl-2-methyl-2-(4-methylpent-3-en-1-yl)chromene-5,7-diol

> <JCHEM_VEBER_RULE>
0

$$$$

Download
3D-SDF for NP0225345 ((2r)-8-benzoyl-2-methyl-2-(4-methylpent-3-en-1-yl)chromene-5,7-diol)
Download
PDB for NP0225345 ((2r)-8-benzoyl-2-methyl-2-(4-methylpent-3-en-1-yl)chromene-5,7-diol)
HEADER    PROTEIN                                 06-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   06-SEP-22         0                                  
HETATM    1  C   UNK     0      -4.733  -1.240   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      -3.216  -1.508   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      -2.226  -0.328   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      -2.689  -2.955   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      -1.173  -3.222   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0      -0.183  -2.043   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       1.334  -2.310   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       0.807  -3.757   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       1.334  -0.770   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       2.667   0.000   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       4.001  -0.770   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       5.335   0.000   0.000  0.00  0.00           C+0
HETATM   13  O   UNK     0       5.335   1.540   0.000  0.00  0.00           O+0
HETATM   14  C   UNK     0       6.668  -0.770   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       6.668  -2.310   0.000  0.00  0.00           C+0
HETATM   16  O   UNK     0       8.002  -3.080   0.000  0.00  0.00           O+0
HETATM   17  C   UNK     0       5.335  -3.080   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       5.335  -4.620   0.000  0.00  0.00           C+0
HETATM   19  O   UNK     0       6.668  -5.390   0.000  0.00  0.00           O+0
HETATM   20  C   UNK     0       4.001  -5.390   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0       4.001  -6.930   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0       2.667  -7.700   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0       1.334  -6.930   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0       1.334  -5.390   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0       2.667  -4.620   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0       4.001  -2.310   0.000  0.00  0.00           C+0
HETATM   27  O   UNK     0       2.667  -3.080   0.000  0.00  0.00           O+0
CONECT    1    2                                                            
CONECT    2    1    3    4                                                  
CONECT    3    2                                                            
CONECT    4    2    5                                                       
CONECT    5    4    6                                                       
CONECT    6    5    7                                                       
CONECT    7    6    8    9   27                                             
CONECT    8    7                                                            
CONECT    9    7   10                                                       
CONECT   10    9   11                                                       
CONECT   11   10   12   26                                                  
CONECT   12   11   13   14                                                  
CONECT   13   12                                                            
CONECT   14   12   15                                                       
CONECT   15   14   16   17                                                  
CONECT   16   15                                                            
CONECT   17   15   18   26                                                  
CONECT   18   17   19   20                                                  
CONECT   19   18                                                            
CONECT   20   18   21   25                                                  
CONECT   21   20   22                                                       
CONECT   22   21   23                                                       
CONECT   23   22   24                                                       
CONECT   24   23   25                                                       
CONECT   25   24   20                                                       
CONECT   26   17   11   27                                                  
CONECT   27   26    7                                                       
MASTER        0    0    0    0    0    0    0    0   27    0   58    0
END

Download
3D PDB for NP0225345 ((2r)-8-benzoyl-2-methyl-2-(4-methylpent-3-en-1-yl)chromene-5,7-diol)
Download
SMILES for NP0225345 ((2r)-8-benzoyl-2-methyl-2-(4-methylpent-3-en-1-yl)chromene-5,7-diol)
CC(C)=CCC[C@@]1(C)OC2=C(C(=O)C3=CC=CC=C3)C(O)=CC(O)=C2C=C1
Download
INCHI for NP0225345 ((2r)-8-benzoyl-2-methyl-2-(4-methylpent-3-en-1-yl)chromene-5,7-diol)
InChI=1S/C23H24O4/c1-15(2)8-7-12-23(3)13-11-17-18(24)14-19(25)20(22(17)27-23)21(26)16-9-5-4-6-10-16/h4-6,8-11,13-14,24-25H,7,12H2,1-3H3/t23-/m1/s1
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View in JSmol
Synonyms
ValueSource
8-Benzoyl-2b-methyl-2-(4-methyl-3-pentenyl)-2H-1-benzopyran-5,7-diolGenerator
8-Benzoyl-2β-methyl-2-(4-methyl-3-pentenyl)-2H-1-benzopyran-5,7-diolGenerator
Chemical FormulaC23H24O4
Average Mass364.4410 Da
Monoisotopic Mass364.16746 Da
IUPAC Name(2R)-8-benzoyl-2-methyl-2-(4-methylpent-3-en-1-yl)-2H-chromene-5,7-diol
Traditional Name(2R)-8-benzoyl-2-methyl-2-(4-methylpent-3-en-1-yl)chromene-5,7-diol
CAS Registry NumberNot Available
SMILES
CC(C)=CCC[C@@]1(C)OC2=C(C(=O)C3=CC=CC=C3)C(O)=CC(O)=C2C=C1
InChI Identifier
InChI=1S/C23H24O4/c1-15(2)8-7-12-23(3)13-11-17-18(24)14-19(25)20(22(17)27-23)21(26)16-9-5-4-6-10-16/h4-6,8-11,13-14,24-25H,7,12H2,1-3H3/t23-/m1/s1
InChI KeyVHBOXYDOVCZHPH-HSZRJFAPSA-N
Experimental Spectra
Not Available
Predicted Spectra
Not Available
Chemical Shift Submissions
Not Available
Species
Species of Origin
Species NameSourceReference
Clusia multifloraLOTUS Database
Chemical Taxonomy
Description Belongs to the class of organic compounds known as benzophenones. These are organic compounds containing a ketone attached to two phenyl groups.
KingdomOrganic compounds  
Super ClassBenzenoids  
ClassBenzene and substituted derivatives  
Sub ClassBenzophenones  
Direct ParentBenzophenones  
Alternative Parents
Substituents
  • Benzophenone
    • 

  • Aryl-phenylketone
    • 

  • Benzopyran
    • 

  • 1-benzopyran
    • 

  • Benzoyl
    • 

  • Aryl ketone
    • 

  • Alkyl aryl ether
    • 

  • 1-hydroxy-2-unsubstituted benzenoid
    • 

  • Vinylogous acid
    • 

  • Ketone
    • 

  • Organoheterocyclic compound
    • 

  • Ether
    • 

  • Oxacycle
    • 

  • Organic oxide
    • 

  • Organooxygen compound
    • 

  • Organic oxygen compound
    • 

  • Hydrocarbon derivative
    • 

  • Aromatic heteropolycyclic compound
Molecular FrameworkAromatic heteropolycyclic compounds
External DescriptorsNot Available
Physical Properties
StateNot Available
Experimental Properties
PropertyValueReference
Melting PointNot AvailableNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogPNot AvailableNot Available
Predicted Properties
PropertyValueSource
logP6.11ChemAxon
pKa (Strongest Acidic)7.31ChemAxon
pKa (Strongest Basic)-5ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count4ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area66.76 ŲChemAxon
Rotatable Bond Count5ChemAxon
Refractivity108.71 m³·mol⁻¹ChemAxon
Polarizability40.4 ųChemAxon
Number of Rings3ChemAxon
BioavailabilityYesChemAxon
Rule of FiveNoChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
HMDB IDNot Available
DrugBank IDNot Available
Phenol Explorer Compound IDNot Available
FoodDB IDNot Available
KNApSAcK IDNot Available
Chemspider IDNot Available
KEGG Compound IDNot Available
BioCyc IDNot Available
BiGG IDNot Available
Wikipedia LinkNot Available
METLIN IDNot Available
PubChem Compound25765598  
PDB IDNot Available
ChEBI IDNot Available
Good Scents IDNot Available
References
General References
  1. LOTUS database [Link]