NP-MRD: Showing NP-Card for 4,7,9-trimethoxy-6-(3,4,5-trimethoxyphenyl)-2h-[1,3]dioxolo[4,5-g]chromen-8-one (NP0219279)

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Record Information

Version

2.0

Created at

2022-09-05 20:13:15 UTC

Updated at

2022-09-05 20:13:15 UTC

NP-MRD ID

NP0219279

Secondary Accession Numbers

None

Natural Product Identification

Common Name

4,7,9-trimethoxy-6-(3,4,5-trimethoxyphenyl)-2h-[1,3]dioxolo[4,5-g]chromen-8-one

Description

4,7,9-Trimethoxy-6-(3,4,5-trimethoxyphenyl)-2H,8H-[1,3]dioxolo[4,5-g]chromen-8-one belongs to the class of organic compounds known as 8-o-methylated flavonoids. These are flavonoids with methoxy groups attached to the C8 atom of the flavonoid backbone. 4,7,9-trimethoxy-6-(3,4,5-trimethoxyphenyl)-2h-[1,3]dioxolo[4,5-g]chromen-8-one is found in Persicaria orientalis. 4,7,9-Trimethoxy-6-(3,4,5-trimethoxyphenyl)-2H,8H-[1,3]dioxolo[4,5-g]chromen-8-one is an extremely weak basic (essentially neutral) compound (based on its pKa).

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1533004231515102D          

 32 35  0  0  0  0            999 V2000
    0.0000   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -1.6500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.0000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.8250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3570   -0.1576    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.8419   -0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3570   -1.4924    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -2.4750    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -2.8875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -2.4750    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1434   -0.4125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8579   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1434    1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8579    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    2.0625    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000    2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  6  7  2  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  7 10  1  0  0  0  0
 10 11  1  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 10 14  2  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 15 18  2  0  0  0  0
  6 18  1  0  0  0  0
 18 19  1  0  0  0  0
  3 19  1  0  0  0  0
 19 20  2  0  0  0  0
  4 21  1  0  0  0  0
 21 22  2  0  0  0  0
 22 23  1  0  0  0  0
 23 24  1  0  0  0  0
 24 25  1  0  0  0  0
 23 26  2  0  0  0  0
 26 27  1  0  0  0  0
 27 28  1  0  0  0  0
 26 29  1  0  0  0  0
 29 30  1  0  0  0  0
 30 31  1  0  0  0  0
 29 32  2  0  0  0  0
 21 32  1  0  0  0  0
M  END

     RDKit          3D

 54 57  0  0  0  0  0  0  0  0999 V2000
   -2.6445    3.7404    0.4532 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5989    2.7094    0.3840 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2552    1.3732    0.2287 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9512    0.9955    0.1347 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5212   -0.3310   -0.0229 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1213   -0.6016   -0.1475 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6806    0.4505   -0.3263 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.9563    0.4141   -0.4598 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6237    1.6286   -0.6387 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9042    2.8359   -0.6680 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.6566    3.5733    0.5159 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9854    1.5738   -0.7800 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.6703    0.3786   -0.7480 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9840   -0.8027   -0.5700 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.6229   -2.0448   -0.5290 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.0759   -2.5645    0.7068 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6225   -0.7891   -0.4250 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8594   -1.9089   -0.2433 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4167   -3.0358   -0.2035 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.4760   -1.8097   -0.1026 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2357   -2.9891    0.0890 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4273   -3.5276    1.3973 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0008    0.6615   -0.9159 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.2161    2.0741   -0.8061 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.9265    2.5876   -0.9706 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5246   -1.2732   -0.0817 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8538   -0.9302    0.0102 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.8202   -1.9049   -0.0523 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4358   -3.2518   -0.2108 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.2240    0.3940    0.1658 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.5714    0.7177    0.2564 O   0  0  0  0  0  0  0  0  0  0  0  0
   -6.2396    1.0002   -0.9763 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1769    4.6724    0.7827 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8489    3.4841    1.1680 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2761    3.9245   -0.5761 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2100    1.8019    0.1892 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.6882    4.1216    0.4741 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.6660    2.8269    1.3504 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.4870    4.2795    0.6493 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.1510   -2.2638    0.7893 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.4712   -2.2009    1.5566 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.0879   -3.6793    0.6869 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3472   -4.1560    1.3426 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5312   -2.6691    2.0730 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.4014   -4.2107    1.6618 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.6662    2.3278    0.1853 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.9292    2.4283   -1.5995 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3196   -2.3141   -0.2252 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7132   -3.5783    0.5891 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8359   -3.3040   -1.1662 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.2812   -3.9429   -0.2898 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1017    2.0390   -1.2852 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.8594    0.3465   -1.7991 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.2998    0.7229   -0.8253 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  2  0
  4  5  1  0
  5 26  2  0
 26 27  1  0
 27 28  1  0
 28 29  1  0
 27 30  2  0
 30 31  1  0
 31 32  1  0
  5  6  1  0
  6 20  2  0
 20 21  1  0
 21 22  1  0
 20 18  1  0
 18 19  2  0
 18 17  1  0
 17 14  2  0
 14 15  1  0
 15 16  1  0
 14 13  1  0
 13 12  2  0
 12 25  1  0
 25 24  1  0
 24 23  1  0
 12  9  1  0
  9 10  1  0
 10 11  1  0
  9  8  2  0
  8  7  1  0
 30  3  1  0
  7  6  1  0
  8 17  1  0
 23 13  1  0
  1 33  1  0
  1 34  1  0
  1 35  1  0
  4 36  1  0
 26 48  1  0
 29 49  1  0
 29 50  1  0
 29 51  1  0
 32 52  1  0
 32 53  1  0
 32 54  1  0
 22 43  1  0
 22 44  1  0
 22 45  1  0
 16 40  1  0
 16 41  1  0
 16 42  1  0
 24 46  1  0
 24 47  1  0
 11 37  1  0
 11 38  1  0
 11 39  1  0
M  END


  Mrv1533004231515102D          

 32 35  0  0  0  0            999 V2000
    0.0000   -2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -1.6500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.0000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.8250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3570   -0.1576    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.8419   -0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3570   -1.4924    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -2.4750    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -2.8875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -2.4750    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1434   -0.4125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8579   -0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1434    1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8579    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    2.0625    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000    2.4750    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  6  7  2  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  7 10  1  0  0  0  0
 10 11  1  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 10 14  2  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 15 18  2  0  0  0  0
  6 18  1  0  0  0  0
 18 19  1  0  0  0  0
  3 19  1  0  0  0  0
 19 20  2  0  0  0  0
  4 21  1  0  0  0  0
 21 22  2  0  0  0  0
 22 23  1  0  0  0  0
 23 24  1  0  0  0  0
 24 25  1  0  0  0  0
 23 26  2  0  0  0  0
 26 27  1  0  0  0  0
 27 28  1  0  0  0  0
 26 29  1  0  0  0  0
 29 30  1  0  0  0  0
 30 31  1  0  0  0  0
 29 32  2  0  0  0  0
 21 32  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0219279

> <DATABASE_NAME>
NP-MRD

> <SMILES>
COC1=CC(=CC(OC)=C1OC)C1=C(OC)C(=O)C2=C(OC)C3=C(OCO3)C(OC)=C2O1

> <INCHI_IDENTIFIER>
InChI=1S/C22H22O10/c1-24-11-7-10(8-12(25-2)16(11)26-3)15-19(28-5)14(23)13-17(27-4)21-22(31-9-30-21)20(29-6)18(13)32-15/h7-8H,9H2,1-6H3

> <INCHI_KEY>
HJYMRTVKQHJJQW-UHFFFAOYSA-N

> <FORMULA>
C22H22O10

> <MOLECULAR_WEIGHT>
446.408

> <EXACT_MASS>
446.121296908

> <JCHEM_ACCEPTOR_COUNT>
10

> <JCHEM_ATOM_COUNT>
54

> <JCHEM_AVERAGE_POLARIZABILITY>
44.93911650370438

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
0

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
4,7,9-trimethoxy-6-(3,4,5-trimethoxyphenyl)-2H,8H-[1,3]dioxolo[4,5-g]chromen-8-one

> <ALOGPS_LOGP>
2.07

> <JCHEM_LOGP>
1.6682652793333337

> <ALOGPS_LOGS>
-4.01

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
4

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA_STRONGEST_BASIC>
-4.089722841700493

> <JCHEM_POLAR_SURFACE_AREA>
100.14000000000003

> <JCHEM_REFRACTIVITY>
111.77269999999997

> <JCHEM_ROTATABLE_BOND_COUNT>
7

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
4.37e-02 g/l

> <JCHEM_TRADITIONAL_IUPAC>
4,7,9-trimethoxy-6-(3,4,5-trimethoxyphenyl)-2H-[1,3]dioxolo[4,5-g]chromen-8-one

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 23-APR-15   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   23-APR-15         0                                  
HETATM    1  C   UNK     0       0.000  -4.620   0.000  0.00  0.00           C+0
HETATM    2  O   UNK     0       0.000  -3.080   0.000  0.00  0.00           O+0
HETATM    3  C   UNK     0       1.334  -2.310   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       1.334  -0.770   0.000  0.00  0.00           C+0
HETATM    5  O   UNK     0       2.667   0.000   0.000  0.00  0.00           O+0
HETATM    6  C   UNK     0       4.001  -0.770   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       5.335   0.000   0.000  0.00  0.00           C+0
HETATM    8  O   UNK     0       5.335   1.540   0.000  0.00  0.00           O+0
HETATM    9  C   UNK     0       6.668   2.310   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       6.668  -0.770   0.000  0.00  0.00           C+0
HETATM   11  O   UNK     0       8.133  -0.294   0.000  0.00  0.00           O+0
HETATM   12  C   UNK     0       9.038  -1.540   0.000  0.00  0.00           C+0
HETATM   13  O   UNK     0       8.133  -2.786   0.000  0.00  0.00           O+0
HETATM   14  C   UNK     0       6.668  -2.310   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       5.335  -3.080   0.000  0.00  0.00           C+0
HETATM   16  O   UNK     0       5.335  -4.620   0.000  0.00  0.00           O+0
HETATM   17  C   UNK     0       4.001  -5.390   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       4.001  -2.310   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       2.667  -3.080   0.000  0.00  0.00           C+0
HETATM   20  O   UNK     0       2.667  -4.620   0.000  0.00  0.00           O+0
HETATM   21  C   UNK     0       0.000   0.000   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0      -1.334  -0.770   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0      -2.667  -0.000   0.000  0.00  0.00           C+0
HETATM   24  O   UNK     0      -4.001  -0.770   0.000  0.00  0.00           O+0
HETATM   25  C   UNK     0      -5.335  -0.000   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0      -2.667   1.540   0.000  0.00  0.00           C+0
HETATM   27  O   UNK     0      -4.001   2.310   0.000  0.00  0.00           O+0
HETATM   28  C   UNK     0      -5.335   1.540   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0      -1.334   2.310   0.000  0.00  0.00           C+0
HETATM   30  O   UNK     0      -1.334   3.850   0.000  0.00  0.00           O+0
HETATM   31  C   UNK     0      -0.000   4.620   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0       0.000   1.540   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4   19                                                  
CONECT    4    3    5   21                                                  
CONECT    5    4    6                                                       
CONECT    6    5    7   18                                                  
CONECT    7    6    8   10                                                  
CONECT    8    7    9                                                       
CONECT    9    8                                                            
CONECT   10    7   11   14                                                  
CONECT   11   10   12                                                       
CONECT   12   11   13                                                       
CONECT   13   12   14                                                       
CONECT   14   13   10   15                                                  
CONECT   15   14   16   18                                                  
CONECT   16   15   17                                                       
CONECT   17   16                                                            
CONECT   18   15    6   19                                                  
CONECT   19   18    3   20                                                  
CONECT   20   19                                                            
CONECT   21    4   22   32                                                  
CONECT   22   21   23                                                       
CONECT   23   22   24   26                                                  
CONECT   24   23   25                                                       
CONECT   25   24                                                            
CONECT   26   23   27   29                                                  
CONECT   27   26   28                                                       
CONECT   28   27                                                            
CONECT   29   26   30   32                                                  
CONECT   30   29   31                                                       
CONECT   31   30                                                            
CONECT   32   29   21                                                       
MASTER        0    0    0    0    0    0    0    0   32    0   70    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₂₂H₂₂O₁₀

Average Mass

446.4080 Da

Monoisotopic Mass

446.12130 Da

IUPAC Name

4,7,9-trimethoxy-6-(3,4,5-trimethoxyphenyl)-2H,8H-[1,3]dioxolo[4,5-g]chromen-8-one

Traditional Name

4,7,9-trimethoxy-6-(3,4,5-trimethoxyphenyl)-2H-[1,3]dioxolo[4,5-g]chromen-8-one

CAS Registry Number

Not Available

SMILES

COC1=CC(=CC(OC)=C1OC)C1=C(OC)C(=O)C2=C(OC)C3=C(OCO3)C(OC)=C2O1

InChI Identifier

InChI=1S/C22H22O10/c1-24-11-7-10(8-12(25-2)16(11)26-3)15-19(28-5)14(23)13-17(27-4)21-22(31-9-30-21)20(29-6)18(13)32-15/h7-8H,9H2,1-6H3

InChI Key

HJYMRTVKQHJJQW-UHFFFAOYSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Persicaria orientalis	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as 8-o-methylated flavonoids. These are flavonoids with methoxy groups attached to the C8 atom of the flavonoid backbone.

Kingdom

Organic compounds

Super Class

Phenylpropanoids and polyketides

Class

Flavonoids

Sub Class

O-methylated flavonoids

Direct Parent

8-O-methylated flavonoids

Alternative Parents

Substituents

8-methoxyflavonoid-skeleton
5-methoxyflavonoid-skeleton
4p-methoxyflavonoid-skeleton
3-methoxyflavonoid-skeleton
3p-methoxyflavonoid-skeleton
Flavone
3-methoxychromone
Chromone
Benzopyran
1-benzopyran
Benzodioxole
Methoxybenzene
Phenol ether
Anisole
Phenoxy compound
Alkyl aryl ether
Pyranone
Monocyclic benzene moiety
Benzenoid
Pyran
Heteroaromatic compound
Vinylogous ester
Oxacycle
Organoheterocyclic compound
Acetal
Ether
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Organic oxygen compound
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	2.07	ALOGPS
logP	1.67	ChemAxon
logS	-4	ALOGPS
pKa (Strongest Basic)	-4.1	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	10	ChemAxon
Hydrogen Donor Count	0	ChemAxon
Polar Surface Area	100.14 Å²	ChemAxon
Rotatable Bond Count	7	ChemAxon
Refractivity	111.77 m³·mol⁻¹	ChemAxon
Polarizability	44.94 Å³	ChemAxon
Number of Rings	4	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	Yes	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

Not Available

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for 4,7,9-trimethoxy-6-(3,4,5-trimethoxyphenyl)-2h-[1,3]dioxolo[4,5-g]chromen-8-one (NP0219279)

MOL for NP0219279 (4,7,9-trimethoxy-6-(3,4,5-trimethoxyphenyl)-2h-[1,3]dioxolo[4,5-g]chromen-8-one)

3D MOL for NP0219279 (4,7,9-trimethoxy-6-(3,4,5-trimethoxyphenyl)-2h-[1,3]dioxolo[4,5-g]chromen-8-one)

3D SDF for NP0219279 (4,7,9-trimethoxy-6-(3,4,5-trimethoxyphenyl)-2h-[1,3]dioxolo[4,5-g]chromen-8-one)

3D-SDF for NP0219279 (4,7,9-trimethoxy-6-(3,4,5-trimethoxyphenyl)-2h-[1,3]dioxolo[4,5-g]chromen-8-one)

PDB for NP0219279 (4,7,9-trimethoxy-6-(3,4,5-trimethoxyphenyl)-2h-[1,3]dioxolo[4,5-g]chromen-8-one)

3D PDB for NP0219279 (4,7,9-trimethoxy-6-(3,4,5-trimethoxyphenyl)-2h-[1,3]dioxolo[4,5-g]chromen-8-one)

SMILES for NP0219279 (4,7,9-trimethoxy-6-(3,4,5-trimethoxyphenyl)-2h-[1,3]dioxolo[4,5-g]chromen-8-one)

INCHI for NP0219279 (4,7,9-trimethoxy-6-(3,4,5-trimethoxyphenyl)-2h-[1,3]dioxolo[4,5-g]chromen-8-one)

Structure for NP0219279 (4,7,9-trimethoxy-6-(3,4,5-trimethoxyphenyl)-2h-[1,3]dioxolo[4,5-g]chromen-8-one)

3D Structure for NP0219279 (4,7,9-trimethoxy-6-(3,4,5-trimethoxyphenyl)-2h-[1,3]dioxolo[4,5-g]chromen-8-one)