NP-MRD: Showing NP-Card for 2'-butylidene-9'-propyl-6,7-dihydro-3'-oxaspiro[2-benzofuran-1,8'-tricyclo[5.2.2.0¹,⁵]undecan]-5'-ene-3,4'-dione (NP0219222)

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Record Information

Version

2.0

Created at

2022-09-05 20:08:53 UTC

Updated at

2022-09-05 20:08:53 UTC

NP-MRD ID

NP0219222

Secondary Accession Numbers

None

Natural Product Identification

Common Name

2'-butylidene-9'-propyl-6,7-dihydro-3'-oxaspiro[2-benzofuran-1,8'-tricyclo[5.2.2.0¹,⁵]undecan]-5'-ene-3,4'-dione

Description

2'-Butylidene-9'-propyl-6,7-dihydro-3H-3'-oxaspiro[2-benzofuran-1,8'-tricyclo[5.2.2.0¹,⁵]Undecan]-5'-ene-3,4'-dione belongs to the class of organic compounds known as isobenzofurans. These are organic aromatic compounds containing an isobenzofuran moiety. 2'-butylidene-9'-propyl-6,7-dihydro-3'-oxaspiro[2-benzofuran-1,8'-tricyclo[5.2.2.0¹,⁵]undecan]-5'-ene-3,4'-dione is found in Angelica sinensis. 2'-Butylidene-9'-propyl-6,7-dihydro-3H-3'-oxaspiro[2-benzofuran-1,8'-tricyclo[5.2.2.0¹,⁵]Undecan]-5'-ene-3,4'-dione is an extremely weak basic (essentially neutral) compound (based on its pKa).

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1533004171517032D          

 28 32  0  0  0  0            999 V2000
   -1.3307   -1.6551    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7153   -1.1056    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0682   -1.3638    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6836   -0.8144    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5154   -0.0067    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2903    0.2518    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2264    1.0903    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8551    1.6246    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.6162    1.2946    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9150    2.1790    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8460    2.3539    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3641    1.7808    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6705    1.0991    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1549    0.5553    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1054    0.7438    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6584    0.1316    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4048   -0.6534    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5982   -0.8263    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3755    1.6261    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7250    2.3734    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.5437    2.2719    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.1070    2.8747    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.7002    1.4619    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.9782    1.0628    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.9629    0.2379    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6696   -0.1878    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3916    0.2114    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4069    1.0362    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  4  3  1  4  0  0  0
  4  5  2  0  0  0  0
  5  6  1  0  0  0  0
  6  7  1  0  0  0  0
  7  8  2  0  0  0  0
  7  9  1  0  0  0  0
  9 10  2  0  0  0  0
 10 11  1  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
  5 14  1  0  0  0  0
  9 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  1  0  0  0  0
 15 19  1  0  0  0  0
 11 19  1  0  0  0  0
 19 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  2  0  0  0  0
 21 23  1  0  0  0  0
 23 24  2  0  0  0  0
 19 24  1  0  0  0  0
 24 25  1  0  0  0  0
 25 26  1  0  0  0  0
 26 27  1  0  0  0  0
 27 28  2  0  0  0  0
 23 28  1  0  0  0  0
M  END

     RDKit          3D

 56 60  0  0  0  0  0  0  0  0999 V2000
    6.1100   -1.2888   -1.6630 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7506   -0.6638   -1.3575 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3169   -1.0867    0.0107 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.0247   -0.5604    0.4561 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2285    0.2578   -0.2367 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5842    0.6995   -1.5032 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.6225    1.5807   -1.9801 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6223    2.1843   -3.1095 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.5870    1.7210   -0.9800 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5477    2.3742   -0.7906 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1926    2.1471    0.5361 C   0  0  2  0  0  0  0  0  0  0  0  0
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   -1.3935    0.6270    0.6630 C   0  0  1  0  0  0  0  0  0  0  0  0
   -1.7744    0.3150    2.0007 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0859    0.8122    2.1349 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6797    1.1848    3.1761 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6216    0.7996    0.7551 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6738    0.3325   -0.0501 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0609   -0.3012   -1.3092 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0641    0.5637   -2.0291 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1092    1.0792   -1.1212 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9089    1.1945    0.1959 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.6870   -0.6763   -2.3827 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.9479   -2.2784   -2.0933 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.7251   -1.3045   -0.7255 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.0143   -0.9962   -2.1387 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.8925    0.4224   -1.4795 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.1018   -0.6925    0.7229 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.3855   -2.1959    0.0771 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.7127   -0.8770    1.4659 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9850    3.0309   -1.5423 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1313    2.6570    0.6597 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.2742    3.5282    1.2022 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5640    2.6351    2.5671 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.7952    0.7581    2.2604 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.9607    2.0122    1.6430 H   0  0  0  0  0  0  0  0  0  0  0  0
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    0.2362   -1.2369    1.9300 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.9318   -1.9850    0.4395 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0191   -1.8093    1.2896 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4894   -2.5000   -0.2793 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0850   -3.6187    2.1487 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7803   -4.4085    0.6976 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8808   -3.9873    2.0272 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4928   -1.3235   -1.1350 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2144   -0.4594   -2.0052 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4721   -0.0184   -2.8715 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5538    1.4460   -2.4701 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.0588    1.3756   -1.4936 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.6931    1.5761    0.8370 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  1  0
  4  5  2  0
  5  6  1  0
  6  7  1  0
  7  8  2  0
  7  9  1  0
  9 10  2  0
 10 11  1  0
 11 12  1  0
 12 13  1  0
 13 14  1  0
 14 15  1  0
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 17 18  1  0
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 19 20  1  1
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 23 24  2  0
 24 25  1  0
 25 26  1  0
 26 27  1  0
 27 28  2  0
 14  5  1  6
 24 19  1  0
 14  9  1  0
 28 23  1  0
 19 11  1  0
  1 29  1  0
  1 30  1  0
  1 31  1  0
  2 32  1  0
  2 33  1  0
  3 34  1  0
  3 35  1  0
  4 36  1  0
 10 37  1  0
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 18 50  1  0
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 27 55  1  0
 28 56  1  0
M  END


  Mrv1533004171517032D          

 28 32  0  0  0  0            999 V2000
   -1.3307   -1.6551    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7153   -1.1056    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0682   -1.3638    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6836   -0.8144    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5154   -0.0067    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2903    0.2518    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2264    1.0903    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8551    1.6246    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.6162    1.2946    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9150    2.1790    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8460    2.3539    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3641    1.7808    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6705    1.0991    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1549    0.5553    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1054    0.7438    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6584    0.1316    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4048   -0.6534    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5982   -0.8263    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3755    1.6261    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7250    2.3734    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.5437    2.2719    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.1070    2.8747    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.7002    1.4619    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.9782    1.0628    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.9629    0.2379    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6696   -0.1878    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3916    0.2114    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4069    1.0362    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  4  3  1  4  0  0  0
  4  5  2  0  0  0  0
  5  6  1  0  0  0  0
  6  7  1  0  0  0  0
  7  8  2  0  0  0  0
  7  9  1  0  0  0  0
  9 10  2  0  0  0  0
 10 11  1  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
  5 14  1  0  0  0  0
  9 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  1  0  0  0  0
 15 19  1  0  0  0  0
 11 19  1  0  0  0  0
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 19 24  1  0  0  0  0
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 25 26  1  0  0  0  0
 26 27  1  0  0  0  0
 27 28  2  0  0  0  0
 23 28  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0219222

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CCCC=C1OC(=O)C2=CC3CCC12C(CCC)C31OC(=O)C2=C1CCC=C2

> <INCHI_IDENTIFIER>
InChI=1S/C24H28O4/c1-3-5-11-20-23-13-12-15(14-18(23)22(26)27-20)24(19(23)8-4-2)17-10-7-6-9-16(17)21(25)28-24/h6,9,11,14-15,19H,3-5,7-8,10,12-13H2,1-2H3

> <INCHI_KEY>
WEQUVWKUIZCSNI-UHFFFAOYSA-N

> <FORMULA>
C24H28O4

> <MOLECULAR_WEIGHT>
380.484

> <EXACT_MASS>
380.198759382

> <JCHEM_ACCEPTOR_COUNT>
2

> <JCHEM_ATOM_COUNT>
56

> <JCHEM_AVERAGE_POLARIZABILITY>
42.23417218919465

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
0

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
2'-butylidene-9'-propyl-6,7-dihydro-3H-3'-oxaspiro[2-benzofuran-1,8'-tricyclo[5.2.2.0¹,⁵]undecan]-5'-ene-3,4'-dione

> <ALOGPS_LOGP>
5.69

> <JCHEM_LOGP>
4.890623324

> <ALOGPS_LOGS>
-4.84

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
5

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA_STRONGEST_BASIC>
-6.6875329812409054

> <JCHEM_POLAR_SURFACE_AREA>
52.6

> <JCHEM_REFRACTIVITY>
109.70989999999999

> <JCHEM_ROTATABLE_BOND_COUNT>
4

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
5.44e-03 g/l

> <JCHEM_TRADITIONAL_IUPAC>
2'-butylidene-9'-propyl-6,7-dihydro-3'-oxaspiro[2-benzofuran-1,8'-tricyclo[5.2.2.0¹,⁵]undecan]-5'-ene-3,4'-dione

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 17-APR-15   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   17-APR-15         0                                  
HETATM    1  C   UNK     0      -2.484  -3.090   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      -1.335  -2.064   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       0.127  -2.546   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       1.276  -1.520   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       0.962  -0.012   0.000  0.00  0.00           C+0
HETATM    6  O   UNK     0      -0.542   0.470   0.000  0.00  0.00           O+0
HETATM    7  C   UNK     0      -0.423   2.035   0.000  0.00  0.00           C+0
HETATM    8  O   UNK     0      -1.596   3.033   0.000  0.00  0.00           O+0
HETATM    9  C   UNK     0       1.150   2.417   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       1.708   4.068   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       3.446   4.394   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       2.546   3.324   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       3.118   2.052   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       2.156   1.037   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       3.930   1.388   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       4.962   0.246   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       4.489  -1.220   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       2.983  -1.543   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       4.434   3.035   0.000  0.00  0.00           C+0
HETATM   20  O   UNK     0       5.087   4.430   0.000  0.00  0.00           O+0
HETATM   21  C   UNK     0       6.615   4.241   0.000  0.00  0.00           C+0
HETATM   22  O   UNK     0       7.666   5.366   0.000  0.00  0.00           O+0
HETATM   23  C   UNK     0       6.907   2.729   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0       5.559   1.984   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0       5.531   0.444   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0       6.850  -0.351   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0       8.198   0.395   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0       8.226   1.934   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4                                                       
CONECT    4    3    5                                                       
CONECT    5    4    6   14                                                  
CONECT    6    5    7                                                       
CONECT    7    6    8    9                                                  
CONECT    8    7                                                            
CONECT    9    7   10   14                                                  
CONECT   10    9   11                                                       
CONECT   11   10   12   19                                                  
CONECT   12   11   13                                                       
CONECT   13   12   14                                                       
CONECT   14   13    5    9   15                                             
CONECT   15   14   16   19                                                  
CONECT   16   15   17                                                       
CONECT   17   16   18                                                       
CONECT   18   17                                                            
CONECT   19   15   11   20   24                                             
CONECT   20   19   21                                                       
CONECT   21   20   22   23                                                  
CONECT   22   21                                                            
CONECT   23   21   24   28                                                  
CONECT   24   23   19   25                                                  
CONECT   25   24   26                                                       
CONECT   26   25   27                                                       
CONECT   27   26   28                                                       
CONECT   28   27   23                                                       
MASTER        0    0    0    0    0    0    0    0   28    0   64    0
END

View in JSmol

Synonyms

Not Available

Chemical Formula

C₂₄H₂₈O₄

Average Mass

380.4840 Da

Monoisotopic Mass

380.19876 Da

IUPAC Name

2'-butylidene-9'-propyl-6,7-dihydro-3H-3'-oxaspiro[2-benzofuran-1,8'-tricyclo[5.2.2.0¹,⁵]undecan]-5'-ene-3,4'-dione

Traditional Name

2'-butylidene-9'-propyl-6,7-dihydro-3'-oxaspiro[2-benzofuran-1,8'-tricyclo[5.2.2.0¹,⁵]undecan]-5'-ene-3,4'-dione

CAS Registry Number

Not Available

SMILES

CCCC=C1OC(=O)C2=CC3CCC12C(CCC)C31OC(=O)C2=C1CCC=C2

InChI Identifier

InChI=1S/C24H28O4/c1-3-5-11-20-23-13-12-15(14-18(23)22(26)27-20)24(19(23)8-4-2)17-10-7-6-9-16(17)21(25)28-24/h6,9,11,14-15,19H,3-5,7-8,10,12-13H2,1-2H3

InChI Key

WEQUVWKUIZCSNI-UHFFFAOYSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Angelica sinensis	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as isobenzofurans. These are organic aromatic compounds containing an isobenzofuran moiety.

Kingdom

Organic compounds

Super Class

Organoheterocyclic compounds

Class

Isobenzofurans

Sub Class

Not Available

Direct Parent

Isobenzofurans

Alternative Parents

Substituents

Isobenzofuran
2-furanone
Dicarboxylic acid or derivatives
Dihydrofuran
Alpha,beta-unsaturated carboxylic ester
Enoate ester
Tetrahydrofuran
Enol ester
Carboxylic acid ester
Lactone
Carboxylic acid derivative
Oxacycle
Hydrocarbon derivative
Organic oxide
Carbonyl group
Organic oxygen compound
Organooxygen compound
Aliphatic heteropolycyclic compound

Molecular Framework

Aliphatic heteropolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	5.69	ALOGPS
logP	4.89	ChemAxon
logS	-4.8	ALOGPS
pKa (Strongest Basic)	-6.7	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	2	ChemAxon
Hydrogen Donor Count	0	ChemAxon
Polar Surface Area	52.6 Å²	ChemAxon
Rotatable Bond Count	4	ChemAxon
Refractivity	109.71 m³·mol⁻¹	ChemAxon
Polarizability	42.23 Å³	ChemAxon
Number of Rings	5	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

72733121

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for 2'-butylidene-9'-propyl-6,7-dihydro-3'-oxaspiro[2-benzofuran-1,8'-tricyclo[5.2.2.0¹,⁵]undecan]-5'-ene-3,4'-dione (NP0219222)

MOL for NP0219222 (2'-butylidene-9'-propyl-6,7-dihydro-3'-oxaspiro[2-benzofuran-1,8'-tricyclo[5.2.2.0¹,⁵]undecan]-5'-ene-3,4'-dione)

3D MOL for NP0219222 (2'-butylidene-9'-propyl-6,7-dihydro-3'-oxaspiro[2-benzofuran-1,8'-tricyclo[5.2.2.0¹,⁵]undecan]-5'-ene-3,4'-dione)

3D SDF for NP0219222 (2'-butylidene-9'-propyl-6,7-dihydro-3'-oxaspiro[2-benzofuran-1,8'-tricyclo[5.2.2.0¹,⁵]undecan]-5'-ene-3,4'-dione)

3D-SDF for NP0219222 (2'-butylidene-9'-propyl-6,7-dihydro-3'-oxaspiro[2-benzofuran-1,8'-tricyclo[5.2.2.0¹,⁵]undecan]-5'-ene-3,4'-dione)

PDB for NP0219222 (2'-butylidene-9'-propyl-6,7-dihydro-3'-oxaspiro[2-benzofuran-1,8'-tricyclo[5.2.2.0¹,⁵]undecan]-5'-ene-3,4'-dione)

3D PDB for NP0219222 (2'-butylidene-9'-propyl-6,7-dihydro-3'-oxaspiro[2-benzofuran-1,8'-tricyclo[5.2.2.0¹,⁵]undecan]-5'-ene-3,4'-dione)

SMILES for NP0219222 (2'-butylidene-9'-propyl-6,7-dihydro-3'-oxaspiro[2-benzofuran-1,8'-tricyclo[5.2.2.0¹,⁵]undecan]-5'-ene-3,4'-dione)

INCHI for NP0219222 (2'-butylidene-9'-propyl-6,7-dihydro-3'-oxaspiro[2-benzofuran-1,8'-tricyclo[5.2.2.0¹,⁵]undecan]-5'-ene-3,4'-dione)

Structure for NP0219222 (2'-butylidene-9'-propyl-6,7-dihydro-3'-oxaspiro[2-benzofuran-1,8'-tricyclo[5.2.2.0¹,⁵]undecan]-5'-ene-3,4'-dione)

3D Structure for NP0219222 (2'-butylidene-9'-propyl-6,7-dihydro-3'-oxaspiro[2-benzofuran-1,8'-tricyclo[5.2.2.0¹,⁵]undecan]-5'-ene-3,4'-dione)