NP-MRD: Showing NP-Card for (2r,4as,6br,8ar,12ar,12br,14ar,14bs)-2,6b,9,9,12a,14b-hexamethyl-10-oxo-3,4,5,7,8,8a,11,12,12b,13,14,14a-dodecahydro-1h-picene-2,4a-dicarboxylic acid (NP0217005)

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Record Information

Version

1.0

Created at

2022-09-05 17:11:39 UTC

Updated at

2022-09-05 17:11:39 UTC

NP-MRD ID

NP0217005

Secondary Accession Numbers

None

Natural Product Identification

Common Name

(2r,4as,6br,8ar,12ar,12br,14ar,14bs)-2,6b,9,9,12a,14b-hexamethyl-10-oxo-3,4,5,7,8,8a,11,12,12b,13,14,14a-dodecahydro-1h-picene-2,4a-dicarboxylic acid

Description

18-Methyl-3-oxo-27-norolean-14-ene-28,29-dioic acid belongs to the class of organic compounds known as triterpenoids. These are terpene molecules containing six isoprene units. (2r,4as,6br,8ar,12ar,12br,14ar,14bs)-2,6b,9,9,12a,14b-hexamethyl-10-oxo-3,4,5,7,8,8a,11,12,12b,13,14,14a-dodecahydro-1h-picene-2,4a-dicarboxylic acid is found in Schefflera bodinieri. It was first documented in 2016 (PMID: 27066716). Based on a literature review a significant number of articles have been published on 18-Methyl-3-oxo-27-norolean-14-ene-28,29-dioic acid (PMID: 30987109) (PMID: 30445878) (PMID: 29950074) (PMID: 27866320).

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1652309052219112D          

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M  END

     RDKit          3D

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M  END


  Mrv1652309052219112D          

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    9.1263   -2.0625    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    8.7138   -2.7770    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.3013   -2.0625    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    7.8888   -2.7770    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.0638   -2.7770    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.6513   -2.0625    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  2  4  1  0  0  0  0
  4  5  2  0  0  0  0
  4  6  1  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  6  0  0  0
  8 10  1  0  0  0  0
  2 10  1  0  0  0  0
 10 11  1  6  0  0  0
 11 12  1  0  0  0  0
 12 13  1  0  0  0  0
 13 14  1  6  0  0  0
 13 15  1  0  0  0  0
 15 16  2  0  0  0  0
 16 17  1  0  0  0  0
 17 18  1  0  0  0  0
 18 19  1  6  0  0  0
 19 20  2  0  0  0  0
 19 21  1  0  0  0  0
 18 22  1  0  0  0  0
 22 23  1  0  0  0  0
 23 24  1  0  0  0  0
 24 25  1  6  0  0  0
 24 26  1  1  0  0  0
 26 27  2  0  0  0  0
 26 28  1  0  0  0  0
 24 29  1  0  0  0  0
 29 30  1  0  0  0  0
 18 30  1  0  0  0  0
 30 31  1  6  0  0  0
 30 32  1  0  0  0  0
 32 15  1  1  0  0  0
 32 33  1  0  0  0  0
 33 34  1  0  0  0  0
 35 34  1  6  0  0  0
 13 35  1  0  0  0  0
  8 35  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0217005

> <DATABASE_NAME>
NP-MRD

> <SMILES>
CC1(C)[C@@H]2CC[C@]3(C)[C@H](CC[C@H]4C3=CC[C@]3(CC[C@](C)(C[C@@]43C)C(O)=O)C(O)=O)[C@@]2(C)CCC1=O

> <INCHI_IDENTIFIER>
InChI=1S/C30H44O5/c1-25(2)20-10-12-27(4)18-9-14-30(24(34)35)16-15-26(3,23(32)33)17-29(30,6)19(18)7-8-21(27)28(20,5)13-11-22(25)31/h9,19-21H,7-8,10-17H2,1-6H3,(H,32,33)(H,34,35)/t19-,20-,21-,26+,27-,28-,29-,30-/m0/s1

> <INCHI_KEY>
XHBPSUZBMFZPRC-ACEHZZNRSA-N

> <FORMULA>
C30H44O5

> <MOLECULAR_WEIGHT>
484.677

> <EXACT_MASS>
484.318874517

> <JCHEM_ACCEPTOR_COUNT>
5

> <JCHEM_ATOM_COUNT>
79

> <JCHEM_AVERAGE_POLARIZABILITY>
55.13043051839376

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
2

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(2R,4aS,6bR,8aR,12aR,12bR,14aR,14bS)-2,6b,9,9,12a,14b-hexamethyl-10-oxo-1,2,3,4,4a,5,6b,7,8,8a,9,10,11,12,12a,12b,13,14,14a,14b-icosahydropicene-2,4a-dicarboxylic acid

> <JCHEM_LOGP>
6.350053737999998

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
5

> <JCHEM_PHYSIOLOGICAL_CHARGE>
-2

> <JCHEM_PKA>
4.784316634487698

> <JCHEM_PKA_STRONGEST_ACIDIC>
4.114529863663858

> <JCHEM_PKA_STRONGEST_BASIC>
-7.470885037743603

> <JCHEM_POLAR_SURFACE_AREA>
91.67

> <JCHEM_REFRACTIVITY>
134.51939999999996

> <JCHEM_ROTATABLE_BOND_COUNT>
2

> <JCHEM_RULE_OF_FIVE>
0

> <JCHEM_TRADITIONAL_IUPAC>
(2R,4aS,6bR,8aR,12aR,12bR,14aR,14bS)-2,6b,9,9,12a,14b-hexamethyl-10-oxo-3,4,5,7,8,8a,11,12,12b,13,14,14a-dodecahydro-1H-picene-2,4a-dicarboxylic acid

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 05-SEP-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   05-SEP-22         0                                  
HETATM    1  C   UNK     0       7.119  -1.990   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       8.566  -2.516   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       8.833  -1.000   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       7.796  -3.850   0.000  0.00  0.00           C+0
HETATM    5  O   UNK     0       6.256  -3.850   0.000  0.00  0.00           O+0
HETATM    6  C   UNK     0       8.566  -5.184   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0      10.106  -5.184   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0      10.876  -3.850   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0      11.646  -5.184   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0      10.106  -2.516   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0      10.876  -1.183   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0      12.416  -1.183   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0      13.186  -2.516   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0      13.956  -1.183   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0      14.726  -2.516   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0      15.496  -1.183   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0      17.036  -1.183   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0      17.806  -2.516   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0      18.576  -1.183   0.000  0.00  0.00           C+0
HETATM   20  O   UNK     0      20.116  -1.183   0.000  0.00  0.00           O+0
HETATM   21  O   UNK     0      17.806   0.151   0.000  0.00  0.00           O+0
HETATM   22  C   UNK     0      19.346  -2.516   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0      20.116  -3.850   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0      19.346  -5.184   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0      20.793  -5.710   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0      19.078  -6.700   0.000  0.00  0.00           C+0
HETATM   27  O   UNK     0      20.258  -7.690   0.000  0.00  0.00           O+0
HETATM   28  O   UNK     0      17.631  -7.227   0.000  0.00  0.00           O+0
HETATM   29  C   UNK     0      17.806  -5.184   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0      17.036  -3.850   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0      16.266  -5.184   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0      15.496  -3.850   0.000  0.00  0.00           C+0
HETATM   33  C   UNK     0      14.726  -5.184   0.000  0.00  0.00           C+0
HETATM   34  C   UNK     0      13.186  -5.184   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0      12.416  -3.850   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3    4   10                                             
CONECT    3    2                                                            
CONECT    4    2    5    6                                                  
CONECT    5    4                                                            
CONECT    6    4    7                                                       
CONECT    7    6    8                                                       
CONECT    8    7    9   10   35                                             
CONECT    9    8                                                            
CONECT   10    8    2   11                                                  
CONECT   11   10   12                                                       
CONECT   12   11   13                                                       
CONECT   13   12   14   15   35                                             
CONECT   14   13                                                            
CONECT   15   13   16   32                                                  
CONECT   16   15   17                                                       
CONECT   17   16   18                                                       
CONECT   18   17   19   22   30                                             
CONECT   19   18   20   21                                                  
CONECT   20   19                                                            
CONECT   21   19                                                            
CONECT   22   18   23                                                       
CONECT   23   22   24                                                       
CONECT   24   23   25   26   29                                             
CONECT   25   24                                                            
CONECT   26   24   27   28                                                  
CONECT   27   26                                                            
CONECT   28   26                                                            
CONECT   29   24   30                                                       
CONECT   30   29   18   31   32                                             
CONECT   31   30                                                            
CONECT   32   30   15   33                                                  
CONECT   33   32   34                                                       
CONECT   34   33   35                                                       
CONECT   35   34   13    8                                                  
MASTER        0    0    0    0    0    0    0    0   35    0   78    0
END

View in JSmol

Synonyms

Value	Source
18-Methyl-3-oxo-27-norolean-14-ene-28,29-dioate	Generator

Chemical Formula

C₃₀H₄₄O₅

Average Mass

484.6770 Da

Monoisotopic Mass

484.31887 Da

IUPAC Name

(2R,4aS,6bR,8aR,12aR,12bR,14aR,14bS)-2,6b,9,9,12a,14b-hexamethyl-10-oxo-1,2,3,4,4a,5,6b,7,8,8a,9,10,11,12,12a,12b,13,14,14a,14b-icosahydropicene-2,4a-dicarboxylic acid

Traditional Name

(2R,4aS,6bR,8aR,12aR,12bR,14aR,14bS)-2,6b,9,9,12a,14b-hexamethyl-10-oxo-3,4,5,7,8,8a,11,12,12b,13,14,14a-dodecahydro-1H-picene-2,4a-dicarboxylic acid

CAS Registry Number

Not Available

SMILES

CC1(C)[C@@H]2CC[C@]3(C)[C@H](CC[C@H]4C3=CC[C@]3(CC[C@](C)(C[C@@]43C)C(O)=O)C(O)=O)[C@@]2(C)CCC1=O

InChI Identifier

InChI=1S/C30H44O5/c1-25(2)20-10-12-27(4)18-9-14-30(24(34)35)16-15-26(3,23(32)33)17-29(30,6)19(18)7-8-21(27)28(20,5)13-11-22(25)31/h9,19-21H,7-8,10-17H2,1-6H3,(H,32,33)(H,34,35)/t19-,20-,21-,26+,27-,28-,29-,30-/m0/s1

InChI Key

XHBPSUZBMFZPRC-ACEHZZNRSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Heptapleurum bodinieri	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as triterpenoids. These are terpene molecules containing six isoprene units.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Prenol lipids

Sub Class

Triterpenoids

Direct Parent

Triterpenoids

Alternative Parents

Substituents

Triterpenoid
Oxosteroid
17-oxosteroid
Steroid
Dicarboxylic acid or derivatives
Cyclic ketone
Ketone
Carboxylic acid
Carboxylic acid derivative
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Carbonyl group
Aliphatic homopolycyclic compound

Molecular Framework

Aliphatic homopolycyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	6.35	ChemAxon
pKa (Strongest Acidic)	4.11	ChemAxon
pKa (Strongest Basic)	-7.5	ChemAxon
Physiological Charge	-2	ChemAxon
Hydrogen Acceptor Count	5	ChemAxon
Hydrogen Donor Count	2	ChemAxon
Polar Surface Area	91.67 Å²	ChemAxon
Rotatable Bond Count	2	ChemAxon
Refractivity	134.52 m³·mol⁻¹	ChemAxon
Polarizability	55.13 Å³	ChemAxon
Number of Rings	5	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

102445408

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

Lee JS, Maarisit W, Abdjul DB, Yamazaki H, Takahashi O, Kirikoshi R, Kanno S, Namikoshi M: Structures and biological activities of triterpenes and sesquiterpenes obtained from Russula lepida. Phytochemistry. 2016 Jul;127:63-8. doi: 10.1016/j.phytochem.2016.03.014. Epub 2016 Apr 8. [PubMed:27066716 ]
Zhang G, Geng H, Zhao C, Li F, Li ZF, Lun B, Wang C, Yu H, Bie S, Li Z: Chemical Constituents with Inhibitory Activity of NO Production from a Wild Edible Mushroom, Russula vinosa Lindbl, May Be Its Nutritional Ingredients. Molecules. 2019 Apr 3;24(7). pii: molecules24071305. doi: 10.3390/molecules24071305. [PubMed:30987109 ]
Wei X, Gao DF, Abe Y, Tanaka Y, Zhu HT, Wang D, Yang CR, Zhang YJ: Triterpenoid saponins with hepatoprotective effects from the fresh leaves of Metapanax delavayi. Nat Prod Res. 2020 May;34(10):1373-1379. doi: 10.1080/14786419.2018.1512987. Epub 2018 Nov 16. [PubMed:30445878 ]
Du L, Wang JX, Chen CD, Wang F, Zhou HY, Du W: [Triterpenoid saponins from roots of Phytolacca acinosa]. Zhongguo Zhong Yao Za Zhi. 2018 Jun;43(12):2552-2556. doi: 10.19540/j.cnki.cjcmm.20180129.001. [PubMed:29950074 ]
Maarisit W, Yamazaki H, Kanno SI, Tomizawa A, Lee JS, Namikoshi M: Protein tyrosine phosphatase 1B inhibitory properties of seco-cucurbitane triterpenes obtained from fruiting bodies of Russula lepida. J Nat Med. 2017 Jan;71(1):334-337. doi: 10.1007/s11418-016-1061-6. Epub 2016 Nov 19. [PubMed:27866320 ]
LOTUS database [Link]

Showing NP-Card for (2r,4as,6br,8ar,12ar,12br,14ar,14bs)-2,6b,9,9,12a,14b-hexamethyl-10-oxo-3,4,5,7,8,8a,11,12,12b,13,14,14a-dodecahydro-1h-picene-2,4a-dicarboxylic acid (NP0217005)

MOL for NP0217005 ((2r,4as,6br,8ar,12ar,12br,14ar,14bs)-2,6b,9,9,12a,14b-hexamethyl-10-oxo-3,4,5,7,8,8a,11,12,12b,13,14,14a-dodecahydro-1h-picene-2,4a-dicarboxylic acid)

3D MOL for NP0217005 ((2r,4as,6br,8ar,12ar,12br,14ar,14bs)-2,6b,9,9,12a,14b-hexamethyl-10-oxo-3,4,5,7,8,8a,11,12,12b,13,14,14a-dodecahydro-1h-picene-2,4a-dicarboxylic acid)

3D SDF for NP0217005 ((2r,4as,6br,8ar,12ar,12br,14ar,14bs)-2,6b,9,9,12a,14b-hexamethyl-10-oxo-3,4,5,7,8,8a,11,12,12b,13,14,14a-dodecahydro-1h-picene-2,4a-dicarboxylic acid)

3D-SDF for NP0217005 ((2r,4as,6br,8ar,12ar,12br,14ar,14bs)-2,6b,9,9,12a,14b-hexamethyl-10-oxo-3,4,5,7,8,8a,11,12,12b,13,14,14a-dodecahydro-1h-picene-2,4a-dicarboxylic acid)

PDB for NP0217005 ((2r,4as,6br,8ar,12ar,12br,14ar,14bs)-2,6b,9,9,12a,14b-hexamethyl-10-oxo-3,4,5,7,8,8a,11,12,12b,13,14,14a-dodecahydro-1h-picene-2,4a-dicarboxylic acid)

3D PDB for NP0217005 ((2r,4as,6br,8ar,12ar,12br,14ar,14bs)-2,6b,9,9,12a,14b-hexamethyl-10-oxo-3,4,5,7,8,8a,11,12,12b,13,14,14a-dodecahydro-1h-picene-2,4a-dicarboxylic acid)

SMILES for NP0217005 ((2r,4as,6br,8ar,12ar,12br,14ar,14bs)-2,6b,9,9,12a,14b-hexamethyl-10-oxo-3,4,5,7,8,8a,11,12,12b,13,14,14a-dodecahydro-1h-picene-2,4a-dicarboxylic acid)

INCHI for NP0217005 ((2r,4as,6br,8ar,12ar,12br,14ar,14bs)-2,6b,9,9,12a,14b-hexamethyl-10-oxo-3,4,5,7,8,8a,11,12,12b,13,14,14a-dodecahydro-1h-picene-2,4a-dicarboxylic acid)

Structure for NP0217005 ((2r,4as,6br,8ar,12ar,12br,14ar,14bs)-2,6b,9,9,12a,14b-hexamethyl-10-oxo-3,4,5,7,8,8a,11,12,12b,13,14,14a-dodecahydro-1h-picene-2,4a-dicarboxylic acid)

3D Structure for NP0217005 ((2r,4as,6br,8ar,12ar,12br,14ar,14bs)-2,6b,9,9,12a,14b-hexamethyl-10-oxo-3,4,5,7,8,8a,11,12,12b,13,14,14a-dodecahydro-1h-picene-2,4a-dicarboxylic acid)