NP-MRD: Showing NP-Card for 2-[1-carboxy-2-({2-[3-ethylidene-5-(methoxycarbonyl)-2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,4-dihydropyran-4-yl]acetyl}oxy)ethyl]-5-methylcyclopentane-1-carboxylic acid (NP0213146)

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Record Information

Version

2.0

Created at

2022-09-05 12:02:24 UTC

Updated at

2022-09-05 12:02:25 UTC

NP-MRD ID

NP0213146

Secondary Accession Numbers

None

Natural Product Identification

Common Name

2-[1-carboxy-2-({2-[3-ethylidene-5-(methoxycarbonyl)-2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,4-dihydropyran-4-yl]acetyl}oxy)ethyl]-5-methylcyclopentane-1-carboxylic acid

Description

2-[1-Carboxy-2-({2-[3-ethylidene-5-(methoxycarbonyl)-2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3,4-dihydro-2H-pyran-4-yl]acetyl}oxy)ethyl]-5-methylcyclopentane-1-carboxylic acid belongs to the class of organic compounds known as terpene glycosides. These are prenol lipids containing a carbohydrate moiety glycosidically bound to a terpene backbone. 2-[1-carboxy-2-({2-[3-ethylidene-5-(methoxycarbonyl)-2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,4-dihydropyran-4-yl]acetyl}oxy)ethyl]-5-methylcyclopentane-1-carboxylic acid is found in Fraxinus americana and Syringa persica. 2-[1-Carboxy-2-({2-[3-ethylidene-5-(methoxycarbonyl)-2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3,4-dihydro-2H-pyran-4-yl]acetyl}oxy)ethyl]-5-methylcyclopentane-1-carboxylic acid is an extremely weak basic (essentially neutral) compound (based on its pKa).

Structure

MOL 3D MOL SDF PDB SMILES InChI


  Mrv1533004171502112D          

 42 44  0  0  0  0            999 V2000
   -1.2375   -7.6974    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6500   -6.9829    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2375   -6.2684    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4125   -6.2684    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6500   -5.5539    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4750   -5.5539    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8875   -4.8395    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4750   -4.1250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8875   -3.4105    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7125   -3.4105    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1250   -4.1250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9500   -4.1250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3625   -4.8395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1875   -4.8395    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3625   -3.4105    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1875   -3.4105    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9500   -2.6961    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3625   -1.9816    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
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    2.0625   -4.8395    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
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  5  6  2  0  0  0  0
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  9 10  1  0  0  0  0
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  8 21  1  0  0  0  0
 21 22  2  0  0  0  0
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 21 24  1  0  0  0  0
  5 24  1  0  0  0  0
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 36 37  1  0  0  0  0
 37 38  2  0  0  0  0
 37 39  1  0  0  0  0
 30 40  1  0  0  0  0
 40 41  2  0  0  0  0
 40 42  1  0  0  0  0
M  END

     RDKit          3D

 80 82  0  0  0  0  0  0  0  0999 V2000
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   -3.1908    0.5805   -0.4714 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.2190    1.0403    0.0447 C   0  0  2  0  0  0  0  0  0  0  0  0
   -4.9246    0.2315    0.9937 O   0  0  0  0  0  0  0  0  0  0  0  0
   -5.5782    1.0906    1.8396 C   0  0  2  0  0  0  0  0  0  0  0  0
   -6.0992    0.4623    3.0866 C   0  0  0  0  0  0  0  0  0  0  0  0
   -7.0090   -0.5521    2.7919 O   0  0  0  0  0  0  0  0  0  0  0  0
   -6.6839    1.8628    1.1575 C   0  0  2  0  0  0  0  0  0  0  0  0
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    3.8359    2.2909   -1.4876 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.8729    2.4359   -2.7500 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.1416    3.2422   -0.7594 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.6501    1.6297   -0.0249 C   0  0  1  0  0  0  0  0  0  0  0  0
    5.2803    2.5169    1.1168 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9283    1.9796    2.3500 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.0050    1.0702    1.8512 C   0  0  1  0  0  0  0  0  0  0  0  0
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    6.5607    0.5482    0.4911 C   0  0  2  0  0  0  0  0  0  0  0  0
    7.7913    0.4155   -0.3321 C   0  0  0  0  0  0  0  0  0  0  0  0
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 42 80  1  0
 33 69  1  0
M  END


  Mrv1533004171502112D          

 42 44  0  0  0  0            999 V2000
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   -4.1250   -4.1250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
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   -4.1250   -2.6961    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7125   -1.9816    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6500   -4.1250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2375   -3.4105    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6500   -2.6961    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2375   -4.8395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4125   -4.8395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -4.1250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4125   -3.4105    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.8250   -4.1250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.2375   -3.4105    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0625   -3.4105    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4750   -2.6961    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2955   -2.6098    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4670   -1.8029    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7525   -1.3904    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6663   -0.5699    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1394   -1.9424    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3325   -1.7709    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7804   -2.3840    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.0775   -0.9862    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.4750   -4.1250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3000   -4.1250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.0625   -4.8395    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  3  5  1  0  0  0  0
  5  6  2  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  1  0  0  0  0
 10 11  1  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 12 15  1  0  0  0  0
 15 16  1  0  0  0  0
 15 17  1  0  0  0  0
 17 18  1  0  0  0  0
 17 19  1  0  0  0  0
 10 19  1  0  0  0  0
 19 20  1  0  0  0  0
  8 21  1  0  0  0  0
 21 22  2  0  0  0  0
 22 23  1  4  0  0  0
 21 24  1  0  0  0  0
  5 24  1  0  0  0  0
 24 25  1  0  0  0  0
 25 26  1  0  0  0  0
 26 27  2  0  0  0  0
 26 28  1  0  0  0  0
 28 29  1  0  0  0  0
 29 30  1  0  0  0  0
 30 31  1  0  0  0  0
 31 32  1  0  0  0  0
 32 33  1  0  0  0  0
 33 34  1  0  0  0  0
 34 35  1  0  0  0  0
 34 36  1  0  0  0  0
 31 36  1  0  0  0  0
 36 37  1  0  0  0  0
 37 38  2  0  0  0  0
 37 39  1  0  0  0  0
 30 40  1  0  0  0  0
 40 41  2  0  0  0  0
 40 42  1  0  0  0  0
M  END
> <DATABASE_ID>
NP0213146

> <DATABASE_NAME>
NP-MRD

> <SMILES>
COC(=O)C1=COC(OC2OC(CO)C(O)C(O)C2O)C(=CC)C1CC(=O)OCC(C1CCC(C)C1C(O)=O)C(O)=O

> <INCHI_IDENTIFIER>
InChI=1S/C27H38O15/c1-4-12-14(7-18(29)39-9-15(23(33)34)13-6-5-11(2)19(13)24(35)36)16(25(37)38-3)10-40-26(12)42-27-22(32)21(31)20(30)17(8-28)41-27/h4,10-11,13-15,17,19-22,26-28,30-32H,5-9H2,1-3H3,(H,33,34)(H,35,36)

> <INCHI_KEY>
HKHBHJCGEATJFY-UHFFFAOYSA-N

> <FORMULA>
C27H38O15

> <MOLECULAR_WEIGHT>
602.586

> <EXACT_MASS>
602.221070524

> <JCHEM_ACCEPTOR_COUNT>
13

> <JCHEM_ATOM_COUNT>
80

> <JCHEM_AVERAGE_POLARIZABILITY>
58.28823225746859

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
6

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
2-[1-carboxy-2-({2-[3-ethylidene-5-(methoxycarbonyl)-2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3,4-dihydro-2H-pyran-4-yl]acetyl}oxy)ethyl]-5-methylcyclopentane-1-carboxylic acid

> <ALOGPS_LOGP>
-0.22

> <JCHEM_LOGP>
-0.3699828020000012

> <ALOGPS_LOGS>
-2.52

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
3

> <JCHEM_PHYSIOLOGICAL_CHARGE>
-2

> <JCHEM_PKA>
4.345892415541076

> <JCHEM_PKA_STRONGEST_ACIDIC>
3.622621933762219

> <JCHEM_PKA_STRONGEST_BASIC>
-2.9810849052288235

> <JCHEM_POLAR_SURFACE_AREA>
235.80999999999997

> <JCHEM_REFRACTIVITY>
137.58520000000001

> <JCHEM_ROTATABLE_BOND_COUNT>
13

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
1.81e+00 g/l

> <JCHEM_TRADITIONAL_IUPAC>
2-[1-carboxy-2-({2-[3-ethylidene-5-(methoxycarbonyl)-2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,4-dihydropyran-4-yl]acetyl}oxy)ethyl]-5-methylcyclopentane-1-carboxylic acid

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 17-APR-15   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   17-APR-15         0                                  
HETATM    1  C   UNK     0      -2.310 -14.368   0.000  0.00  0.00           C+0
HETATM    2  O   UNK     0      -3.080 -13.035   0.000  0.00  0.00           O+0
HETATM    3  C   UNK     0      -2.310 -11.701   0.000  0.00  0.00           C+0
HETATM    4  O   UNK     0      -0.770 -11.701   0.000  0.00  0.00           O+0
HETATM    5  C   UNK     0      -3.080 -10.367   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0      -4.620 -10.367   0.000  0.00  0.00           C+0
HETATM    7  O   UNK     0      -5.390  -9.034   0.000  0.00  0.00           O+0
HETATM    8  C   UNK     0      -4.620  -7.700   0.000  0.00  0.00           C+0
HETATM    9  O   UNK     0      -5.390  -6.366   0.000  0.00  0.00           O+0
HETATM   10  C   UNK     0      -6.930  -6.366   0.000  0.00  0.00           C+0
HETATM   11  O   UNK     0      -7.700  -7.700   0.000  0.00  0.00           O+0
HETATM   12  C   UNK     0      -9.240  -7.700   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0     -10.010  -9.034   0.000  0.00  0.00           C+0
HETATM   14  O   UNK     0     -11.550  -9.034   0.000  0.00  0.00           O+0
HETATM   15  C   UNK     0     -10.010  -6.366   0.000  0.00  0.00           C+0
HETATM   16  O   UNK     0     -11.550  -6.366   0.000  0.00  0.00           O+0
HETATM   17  C   UNK     0      -9.240  -5.033   0.000  0.00  0.00           C+0
HETATM   18  O   UNK     0     -10.010  -3.699   0.000  0.00  0.00           O+0
HETATM   19  C   UNK     0      -7.700  -5.033   0.000  0.00  0.00           C+0
HETATM   20  O   UNK     0      -6.930  -3.699   0.000  0.00  0.00           O+0
HETATM   21  C   UNK     0      -3.080  -7.700   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0      -2.310  -6.366   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0      -3.080  -5.033   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0      -2.310  -9.034   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0      -0.770  -9.034   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0       0.000  -7.700   0.000  0.00  0.00           C+0
HETATM   27  O   UNK     0      -0.770  -6.366   0.000  0.00  0.00           O+0
HETATM   28  O   UNK     0       1.540  -7.700   0.000  0.00  0.00           O+0
HETATM   29  C   UNK     0       2.310  -6.366   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0       3.850  -6.366   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0       4.620  -5.033   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0       6.152  -4.872   0.000  0.00  0.00           C+0
HETATM   33  C   UNK     0       6.472  -3.365   0.000  0.00  0.00           C+0
HETATM   34  C   UNK     0       5.138  -2.595   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0       4.977  -1.064   0.000  0.00  0.00           C+0
HETATM   36  C   UNK     0       3.994  -3.626   0.000  0.00  0.00           C+0
HETATM   37  C   UNK     0       2.487  -3.306   0.000  0.00  0.00           C+0
HETATM   38  O   UNK     0       1.457  -4.450   0.000  0.00  0.00           O+0
HETATM   39  O   UNK     0       2.011  -1.841   0.000  0.00  0.00           O+0
HETATM   40  C   UNK     0       4.620  -7.700   0.000  0.00  0.00           C+0
HETATM   41  O   UNK     0       6.160  -7.700   0.000  0.00  0.00           O+0
HETATM   42  O   UNK     0       3.850  -9.034   0.000  0.00  0.00           O+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4    5                                                  
CONECT    4    3                                                            
CONECT    5    3    6   24                                                  
CONECT    6    5    7                                                       
CONECT    7    6    8                                                       
CONECT    8    7    9   21                                                  
CONECT    9    8   10                                                       
CONECT   10    9   11   19                                                  
CONECT   11   10   12                                                       
CONECT   12   11   13   15                                                  
CONECT   13   12   14                                                       
CONECT   14   13                                                            
CONECT   15   12   16   17                                                  
CONECT   16   15                                                            
CONECT   17   15   18   19                                                  
CONECT   18   17                                                            
CONECT   19   17   10   20                                                  
CONECT   20   19                                                            
CONECT   21    8   22   24                                                  
CONECT   22   21   23                                                       
CONECT   23   22                                                            
CONECT   24   21    5   25                                                  
CONECT   25   24   26                                                       
CONECT   26   25   27   28                                                  
CONECT   27   26                                                            
CONECT   28   26   29                                                       
CONECT   29   28   30                                                       
CONECT   30   29   31   40                                                  
CONECT   31   30   32   36                                                  
CONECT   32   31   33                                                       
CONECT   33   32   34                                                       
CONECT   34   33   35   36                                                  
CONECT   35   34                                                            
CONECT   36   34   31   37                                                  
CONECT   37   36   38   39                                                  
CONECT   38   37                                                            
CONECT   39   37                                                            
CONECT   40   30   41   42                                                  
CONECT   41   40                                                            
CONECT   42   40                                                            
MASTER        0    0    0    0    0    0    0    0   42    0   88    0
END

View in JSmol

Synonyms

Value	Source
2-[1-Carboxy-2-({2-[3-ethylidene-5-(methoxycarbonyl)-2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3,4-dihydro-2H-pyran-4-yl]acetyl}oxy)ethyl]-5-methylcyclopentane-1-carboxylate	Generator

Chemical Formula

C₂₇H₃₈O₁₅

Average Mass

602.5860 Da

Monoisotopic Mass

602.22107 Da

IUPAC Name

2-[1-carboxy-2-({2-[3-ethylidene-5-(methoxycarbonyl)-2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3,4-dihydro-2H-pyran-4-yl]acetyl}oxy)ethyl]-5-methylcyclopentane-1-carboxylic acid

Traditional Name

2-[1-carboxy-2-({2-[3-ethylidene-5-(methoxycarbonyl)-2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,4-dihydropyran-4-yl]acetyl}oxy)ethyl]-5-methylcyclopentane-1-carboxylic acid

CAS Registry Number

Not Available

SMILES

COC(=O)C1=COC(OC2OC(CO)C(O)C(O)C2O)C(=CC)C1CC(=O)OCC(C1CCC(C)C1C(O)=O)C(O)=O

InChI Identifier

InChI=1S/C27H38O15/c1-4-12-14(7-18(29)39-9-15(23(33)34)13-6-5-11(2)19(13)24(35)36)16(25(37)38-3)10-40-26(12)42-27-22(32)21(31)20(30)17(8-28)41-27/h4,10-11,13-15,17,19-22,26-28,30-32H,5-9H2,1-3H3,(H,33,34)(H,35,36)

InChI Key

HKHBHJCGEATJFY-UHFFFAOYSA-N

Experimental Spectra

Not Available

Predicted Spectra

Spectrum Type	Description	Depositor ID	Depositor Organization	Depositor	Deposition Date	View
1D NMR	¹³C NMR Spectrum (1D, 25 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 252 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 50 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 75 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 101 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 126 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 151 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 176 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 201 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 226 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	Wishart Lab	Wishart Lab	David Wishart	2021-06-20	View Spectrum

Chemical Shift Submissions

Not Available

Species

Species of Origin

Species Name	Source	Reference
Fraxinus americana	LOTUS Database	35616633
Syringa persica	LOTUS Database	35616633

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as terpene glycosides. These are prenol lipids containing a carbohydrate moiety glycosidically bound to a terpene backbone.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Prenol lipids

Sub Class

Terpene glycosides

Direct Parent

Terpene glycosides

Alternative Parents

Substituents

Terpene glycoside
Tetracarboxylic acid or derivatives
Glycosyl compound
Secoiridoid-skeleton
O-glycosyl compound
Monocyclic monoterpenoid
Monoterpenoid
Monosaccharide
Oxane
Alpha,beta-unsaturated carboxylic ester
Vinylogous ester
Enoate ester
Methyl ester
Secondary alcohol
Carboxylic acid ester
Polyol
Carboxylic acid derivative
Carboxylic acid
Acetal
Oxacycle
Organoheterocyclic compound
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Carbonyl group
Primary alcohol
Alcohol
Organooxygen compound
Aliphatic heteromonocyclic compound

Molecular Framework

Aliphatic heteromonocyclic compounds

External Descriptors

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	-0.22	ALOGPS
logP	-0.37	ChemAxon
logS	-2.5	ALOGPS
pKa (Strongest Acidic)	3.62	ChemAxon
pKa (Strongest Basic)	-3	ChemAxon
Physiological Charge	-2	ChemAxon
Hydrogen Acceptor Count	13	ChemAxon
Hydrogen Donor Count	6	ChemAxon
Polar Surface Area	235.81 Å²	ChemAxon
Rotatable Bond Count	13	ChemAxon
Refractivity	137.59 m³·mol⁻¹	ChemAxon
Polarizability	58.29 Å³	ChemAxon
Number of Rings	3	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	Yes	ChemAxon

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

73157045

PDB ID

Not Available

ChEBI ID

Not Available

Good Scents ID

Not Available

References

General References

LOTUS database [Link]

Showing NP-Card for 2-[1-carboxy-2-({2-[3-ethylidene-5-(methoxycarbonyl)-2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,4-dihydropyran-4-yl]acetyl}oxy)ethyl]-5-methylcyclopentane-1-carboxylic acid (NP0213146)

MOL for NP0213146 (2-[1-carboxy-2-({2-[3-ethylidene-5-(methoxycarbonyl)-2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,4-dihydropyran-4-yl]acetyl}oxy)ethyl]-5-methylcyclopentane-1-carboxylic acid)

3D MOL for NP0213146 (2-[1-carboxy-2-({2-[3-ethylidene-5-(methoxycarbonyl)-2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,4-dihydropyran-4-yl]acetyl}oxy)ethyl]-5-methylcyclopentane-1-carboxylic acid)

3D SDF for NP0213146 (2-[1-carboxy-2-({2-[3-ethylidene-5-(methoxycarbonyl)-2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,4-dihydropyran-4-yl]acetyl}oxy)ethyl]-5-methylcyclopentane-1-carboxylic acid)

3D-SDF for NP0213146 (2-[1-carboxy-2-({2-[3-ethylidene-5-(methoxycarbonyl)-2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,4-dihydropyran-4-yl]acetyl}oxy)ethyl]-5-methylcyclopentane-1-carboxylic acid)

PDB for NP0213146 (2-[1-carboxy-2-({2-[3-ethylidene-5-(methoxycarbonyl)-2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,4-dihydropyran-4-yl]acetyl}oxy)ethyl]-5-methylcyclopentane-1-carboxylic acid)

3D PDB for NP0213146 (2-[1-carboxy-2-({2-[3-ethylidene-5-(methoxycarbonyl)-2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,4-dihydropyran-4-yl]acetyl}oxy)ethyl]-5-methylcyclopentane-1-carboxylic acid)

SMILES for NP0213146 (2-[1-carboxy-2-({2-[3-ethylidene-5-(methoxycarbonyl)-2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,4-dihydropyran-4-yl]acetyl}oxy)ethyl]-5-methylcyclopentane-1-carboxylic acid)

INCHI for NP0213146 (2-[1-carboxy-2-({2-[3-ethylidene-5-(methoxycarbonyl)-2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,4-dihydropyran-4-yl]acetyl}oxy)ethyl]-5-methylcyclopentane-1-carboxylic acid)

Structure for NP0213146 (2-[1-carboxy-2-({2-[3-ethylidene-5-(methoxycarbonyl)-2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,4-dihydropyran-4-yl]acetyl}oxy)ethyl]-5-methylcyclopentane-1-carboxylic acid)

3D Structure for NP0213146 (2-[1-carboxy-2-({2-[3-ethylidene-5-(methoxycarbonyl)-2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,4-dihydropyran-4-yl]acetyl}oxy)ethyl]-5-methylcyclopentane-1-carboxylic acid)